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MLB DFS Picks for 4/15/26: Daily Fantasy Baseball Strategy and Tips For FanDuel, DraftKings

Ben Rice - Fantasy Baseball Prospects, Waiver Wire Pickups, Draft Sleepers

Casey Wilson's top DraftKings and FanDuel MLB DFS picks for today, Wednesday, 4/15/26. His favorite daily fantasy baseball lineup sleepers and value picks for DFS on DraftKings and FanDuel.

We have another split slate with DraftKings and FanDuel, but we finally have a Wednesday with only three day games, making for an awesome Wednesday night slate of baseball. We have good hitting weather again across the country, making it important to nail down our pitching as always.

I have updated my model to include the actual projections for strikeouts and moneylines for each team. This is important for fantasy points to accumulate predictions on strikeout points and wins. I will be referring to the model throughout today's article.

This article will provide my daily fantasy baseball lineup picks for DraftKings and FanDuel on 4/15/2026, with the slate starting at 7:05 p.m. ET on DraftKings and 6:40 p.m. ET on FanDuel. The lineup picks will showcase elite players, mid-priced options, and value plays. You can also read more DFS advice and lineup picks for other sports here. Monitoring injury news and today's MLB starting lineups is always essential.

 

Top MLB DFS Pitcher for DraftKings, FanDuel

Spencer Arrighetti, SP - HOU ($7.0K DK/$7.3K FD)

Spencer Arrighetti makes his season debut tonight for the Astros against the Colorado Rockies at Daikin Park. Arrighetti has been great in Triple-A in his three starts. He has a 1.74 ERA, with 16 Ks in 10.1 IP.

My model projects him for 4.31 Ks and the Rockies for a 4.4 implied run total, but he still looks good to me given his price on both sites. In 2025, Arrighetti posted a 5.03 xFIP, 19.9% K%, and 10.7% SwStr%. 2026 projections have him posting a 4.80 xFIP, 21.5% K%, and 10.8% SwStr%.

The Rockies this season against RHP have a 26.3% K%, .695 OPS, and an 82 wRC+. I don't love this spot, but when you bake in the price, he's too cheap and should be considered, in all formats, a SP1.

 

Top MLB DFS Stack for DraftKings, FanDuel

New York Yankees (Model Projected IRT (Implied Run Total)- 5.9) vs. Jack Kochanowicz

I said this multiple times last year, and I will say it again. I have no idea how Jack Kochanowicz is still pitching in the big leagues, but here we are. He will square off against the New York Yankees tonight at Yankee Stadium, with the weather being in the mid-80s and a 10+ mph wind blowing out to dead center.

My model projects the Yankees for a 5.9 implied run total, which is the highest on tonight's slate. Kochanowicz has allowed a 5.03 xFIP, 16.7% K%, 1.26 WHIP, and a 34.7% Hard Hit% this season. He has been lucky this season, pitching to a 3.24 ERA but a 5.41 SIERA. This is the negative regression spot.

I have highlighted the Yankees' struggles against LHP, but the opposite is true against RHP. They have a .763 OPS and a 121 wRC+ against RHP in 2026. Fire up the Yankees.

Favorite Targets: Ben Rice, Cody Bellinger, Trent Grisham, Jazz Chisholm Jr., Aaron Judge, Giancarlo Stanton

 

Top MLB DFS Hitter for DraftKings, FanDuel

Ben Rice, 1B/C (FD Only) - NYY ($5.5K DK/$4.2K FD)

Ben Rice is an elite play tonight and my favorite play from the Yankees. I will be overexposed to him in all formats. Kochanowicz allowed LHH to slash .309/.393/.489 with 17 HRs against him last season. Rice is white hot, slashing .400/.551/.914 with a 1.465 OPS and four HRs against RHP already this season.

 

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