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Sep 23, 2026, 9:10 PM ET

Georgia running back Nate Frazier (undisclosed) is questionable to play in the Bulldogs' Week 4 meeting with SEC foe Oklahoma, per the SEC availability report. Frazier has been highly productive to start the season, recording five touchdowns rushing over his team's first three games. He is averaging 8.4 yards per carry while totaling 202 yards rushing entering this Saturday's game. Frazier is RotoBaller's 39th-ranked running back and is projected to score 11.8 fantasy points against the Sooners this weekend. Oklahoma has allowed 111 yards rushing per game this season. Last week, the Sooners gave up just 69 yards on the ground during a slim 14-6 win over New Mexico.--Alex Brasky
Source: SEC availability report
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Sep 23, 2026, 9:10 PM ET

Seattle Seahawks wide receiver Cooper Kupp (back) was a limited participant during Wednesday's practice, John Boyle of the Seahawks' official site reports. Kupp was dealing with a back issue last week as well, but he still managed to suit up on Sunday. He hauled in both his targets for 20 yards in the win over the Arizona Cardinals. The expectation is that the Seahawks are just being careful with the veteran wideout to begin the week. Barring any setbacks, Kupp should be ready to go for the Week 3 matchup against the Washington Commanders. Kupp has four receptions for 55 yards through the first two games of the season. He offers some deep league appeal, but he isn't someone who must be started right now.--Andy Webb
Source: John Boyle
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Sep 23, 2026, 9:07 PM ET

New York Knicks center Karl-Anthony Towns is unlikely to agree to an extension before training camp, according to ESPN's Shams Charania and Vincent Goodwill. The 30-year-old is eligible for a four-year deal worth up to roughly $273 million, while Stefan Bondy of the New York Post reports that the Knicks are seeking a discount from the max. Towns averaged 20.1 points, 11.9 rebounds, and 3.0 assists across 75 games last season and enters the final guaranteed year of his current deal, with a player option for 2027-28. The contract situation should not affect his role, leaving Towns in position for another high-volume fantasy season.--Brian Dailisan
Source: Shams Charania
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Sep 23, 2026, 9:05 PM ET

Boston Red Sox outfielder Ceddanne Rafaela (hamstring) left Wednesday's game early against the Cleveland Guardians due to tightness in his right hamstring, according to Tim Healey of The Boston Globe. Before Rafaela was replaced in center field by Jarren Duran, he went 1-for-1 at the plate in his first game back from a stay on the 10-day injured list this month due to a right-quadriceps injury. The Red Sox initially reported that Rafaela left the game at Fenway Park due to cramping, so hopefully it is nothing serious with the playoffs set to start next week. The 26-year-old's next chance to return to the starting lineup will be for Thursday's series finale against Cleveland. If Rafaela cannot finish out the final week of the 2026 regular season, he could be up in the air for the wild-card series next week against the division-rival New York Yankees. He was an All-Star for the first time this year and came into Wednesday's tilt hitting a nice .282/.317/.443 with a .760 OPS, career-high-tying 16 home runs, 70 RBI, 17 steals, and 67 runs scored across 135 games played and 569 plate appearances in his third full season in the majors.--Keith Hernandez
Source: The Boston Globe - Tim Healey
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Sep 23, 2026, 9:00 PM ET

Texas running back Hollywood Smothers' status for Saturday's SEC matchup with Tennessee is up in the air, as he is questionable with a lower-body injury, according to On3's Pete Nakos. Smothers has led the Longhorns with 198 yards rushing on 41 carries this season, scoring two rushing touchdowns, which is tied for the team lead with fellow running back Raleek Brown. Smothers averaged 5.4 yards per carry during a win over UTSA this past week, adding two receptions for 11 yards. He has seven receptions for 54 yards and a touchdown receiving on the year. Tennessee limited Kennesaw State's leading ball-carrier, quarterback Rickie Collins, to just 2.6 yards per carry a week ago. --Alex Brasky
Source: Pete Nakos
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Sep 23, 2026, 8:55 PM ET

The Toronto Blue Jays announced on Wednesday that they placed right-hander Dylan Cease (shoulder) on the 15-day injured list (retroactive to Sept. 20) with inflammation in his right shoulder and recalled right-handers Chase Lee and CJ Van Eyk from Triple-A Buffalo in corresponding moves. With the Blue Jays eliminated from postseason contention, they will shut Cease down for the final week of the regular season. The Blue Jays already announced this week that the 30-year-old All-Star will not need surgery on his shoulder, so he should be ready in plenty of time for spring training next year. Cease really liked pitching north of the border in his first year with the Jays in 2026, as he went 11-6 with a 2.40 ERA (league-best 2.55 FIP) and 1.10 WHIP with a career-high 239 strikeouts and 78 walks in 169 innings across 29 starts in his eighth season in the majors. He now has six straight seasons with 200-plus strikeouts, making Cease an extremely attractive strikeout arm in fantasy baseball drafts next spring.--Keith Hernandez
Source: Toronto Blue Jays
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Sep 23, 2026, 8:53 PM ET

Florida wide receiver Eric Singleton (ankle) has a chance to suit up in Week 4, as he has been listed as questionable and will be a game-time decision for the Gators against Ole Miss, per ESPN's Pete Thamel. Singleton injured his ankle in Week 1 before he could record a reception, but the Auburn transfer finished the 2025 campaign with 58 catches for 534 yards and three touchdowns. Before his injury, it was expected he would be a key element of Florida's passing game this season. The Gators' leading receiver, Vernell Brown III, has 4 receptions for 246 yards and two touchdowns this year. This weekend, Florida takes on a Rebels defense that is fresh off a solid effort against LSU quarterback Sam Leavitt, who was limited to just 5.9 yards per attempt in a 32-24 defeat.--Alex Brasky
Source: Pete Thamel
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Sep 23, 2026, 8:47 PM ET

Houston Astros shortstop Jeremy Pena (wrist) is not in the starting lineup for Wednesday's game on the road against the division-rival Seattle Mariners, per MLB.com. Nick Allen is getting the start at shortstop and will hit ninth against Mariners right-hander George Kirby. Pena was pulled late in Tuesday's contest against the Mariners after he was hit by a pitch on his right wrist earlier in the game. It is unclear if X-rays came back negative for the 29-year-old, so for now, fantasy managers should consider him day-to-day. Check back to see if Pena is available to return for Thursday's series opener against the division-rival Athletics in Sacramento. It is bad timing for the Astros for Pena to be dinged up with the Astros battling the Texas Rangers for the American League West division with just five games left to play. Pena has been great for Houston when he has been healthy in 2026, hitting .275/.325/.469 with 20 home runs, 51 RBI, 77 runs scored, and 10 stolen bases in 426 at-bats. Hopefully, he will be ready for the final series of the regular season this weekend in Sacramento.--Keith Hernandez
Source: MLB.com
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Sep 23, 2026, 8:46 PM ET

Atlanta Falcons quarterback Michael Penix Jr. (knee) is set to make his season debut in Week 3 on Thursday Night Football, which will be a road contest against the Green Bay Packers. The former first-rounder represents an upgrade at quarterback, with backup QBs Cooper Rush and Jack Strand filling in at quarterback for the Falcons' first two contests. While it is an upgrade for Atlanta, fantasy expectations should be tempered, as the left-handed QB averaged only 225 yards passing in the eight full games he played last year while posting a 9:3 TD:INT in those contests. The University of Washington product wasn't a factor in the run game with his legs either, and there's no reason to believe that will be any different after the return from his knee injury. Green Bay's defense yielded three passing scores in Week 1, but just one in Week 2, and has given up just 175 passing yards per game, which is top 10 in the league. As it stands, the 26-year-old sits at the bottom of the barrel in terms of QB rankings for Week 3 at RotoBaller, so there are likely better streaming options available on waiver wires and he'd be quite the gamble in DFS contests.--Jarod Rupp
Source: RotoBaller
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Sep 23, 2026, 8:41 PM ET

Ole Miss running back Kewan Lacy (shoulder) has been marked questionable and will be a game-time decision for the Rebels' Week 4 contest against Florida, according to On3's Pete Nakos. Lacy left this past week's win over LSU with a shoulder injury and did not return. He finished the game with nine carries for 43 yards and a touchdown, while also recording two receptions for -2 yards. He is RotoBaller's RB26 and is projected to score 14.1 fantasy points against the Gators this week. The Florida defense has been stout against the run this season, allowing just 94.7 yards rushing per game.--Alex Brasky
Source: Pete Nakos
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Sep 23, 2026, 8:36 PM ET

The whirlwind week at Royal Birkdale for Ryan Fox inevitably punched his ticket to this week's President's Cup at Medinah, as the Champion Golfer of the Year is a solid asterisk for a team that needs all the help it can get. There's still a major question of how the New Zealander will handle himself in this atmosphere and, like most other pairings for this team, who will be an optimal partner to earn points. Players who inconsistently thrive in all four major facets aren't always easy teammates, especially when he ranked no higher than 77th in any strokes gained metric. Outside of his length off the tee, the rest of his game is hard to trust. No one would be surprised to see Fox struggle this week.--Todd McGill
Source: PGA Tour
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Sep 23, 2026, 8:35 PM ET

Washington Commanders tight end Chig Okonkwo (hamstring) was not at the team's first practice of the week on Wednesday, according to Tashan Reed of The Athletic. Okonkwo suffered a hamstring injury in the Week 1 loss to the division-rival Philadelphia Eagles and was unable to play in last week's loss to the division-rival Dallas Cowboys. In Okonkwo's absence on Sunday in Dallas, tight ends Ben Sinnott and Colson Yankoff combined for two catches for 20 yards, while John Bates did not see a single pass-game target. The 27-year-old Okonkwo had a case for a 2026 breakout in his move to D.C. with quarterback Jayden Daniels (elbow), but that is not looking so hot after Okonkwo's hamstring injury in Week 1 and Daniels' dislocated left elbow in Week 2. Even if Okonkwo makes his return in Week 3 this Sunday against the Seattle Seahawks, he will be best left on the bench in deeper leagues with veteran Marcus Mariota taking over at QB.--Keith Hernandez
Source: The Athletic - Tashan Reed
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Sep 23, 2026, 8:32 PM ET

Oregon tight end Jamari Johnson (undisclosed) is questionable for the Ducks entering Saturday's matchup with USC, per the Big Ten availability report. Oregon head coach Dan Lanning said earlier this week that Johnson is "likely to play," according to 247 Sports' Matt Prehm, though a final decision regarding his status has yet to be reached as of Wednesday night. Johnson has missed each of the Ducks' previous two games after finishing a thrilling Week 1 win over Boise State with four receptions for 57 yards and a touchdown. USC allowed Rutgers to gain 292 yards through the air last week during a high-scoring 42-35 win over the Scarlet Knights.--Alex Brasky
Source: Matt Prehm
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Sep 23, 2026, 8:30 PM ET

Buffalo Bills wide receiver Keon Coleman (ankle) was listed as a non-participant in practice on Wednesday due to an ankle injury, according to the team. After catching just one pass for one yard in the season-opening win over the Houston Texans, Coleman caught all six of his targets for 63 yards in last Thursday's win over the Detroit Lions in a game in which fellow wideout DJ Moore went down with a serious-looking shoulder injury. Moore was diagnosed with an AC joint sprain and was limited in practice on Wednesday, so he might not end up missing any time at all. Meanwhile, the 23-year-old Coleman is dealing with an ankle injury of his own that could have him up in the air to face the visiting Los Angeles Chargers this Sunday in Week 3. Coleman's waiver-wire case basically hinges on Moore's health, and with Moore potentially not missing any time, Coleman is no longer very attractive. If he cannot play against the Chargers, Khalil Shakir and Joshua Palmer could see more involvement behind Moore (assuming he plays).--Keith Hernandez
Source: Buffalo Bills PR
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Sep 23, 2026, 8:20 PM ET

USC wide receiver Trent Mosley (undisclosed) is doubtful to play on Saturday against Oregon, according to the Big Ten availability report. Mosley missed this past week's win over Rutgers after he started the season with 255 yards receiving and four touchdowns through the Trojans' first three games. In his absence, Kayden Dixon-Wyatt led USC in yards receiving and receptions with five catches for 77 yards, while Corey Simms finished a 42-35 win over the Scarlet Knights with four receptions for 72 yards and a touchdown. It was just two weeks ago that Oregon's pass defense allowed Oklahoma State wide receiver Wyatt Young to break out with five receptions for 121 yards and a touchdown during an uncharacteristically poor performance for the Ducks' resistance.--Alex Brasky
Source: Big Ten availability report
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