November 23, 2025
Detroit Lions right tackle Penei Sewell (ankle) is officially active for Sunday's Week 12 contest against the New York Giants. He had been listed as questionable after logging back-to-back limited practices. The 25-year-old will suit up for his 11th game of the 2025 season, providing key protection to
Jared Goff,
Jahmyr Gibbs, and
David Montgomery. Sewell has allowed zero sacks this season, so his presence is quite important as the Lions look to slow down a Giants pass rush headlined by Brian Burns, who has 13 sacks.
--Andersen PickardSource: Madelyn Burke
November 23, 2025
Minnesota Vikings edge rusher Jonathan Greenard (shoulder) is officially inactive for Sunday's Week 12 contest against the Green Bay Packers. He had been listed as questionable after logging a pair of limited practice sessions. The 28-year-old Florida product will ultimately miss his second consecutive game, leaving a large void within Minnesota's defensive front. After all, he had 31 tackles, two sacks, and one forced fumble through his first nine contests this year. Dallas Turner is expected to earn the start in Greenard's absence. Turner was a productive fill-in last week, amassing seven tackles and one sack.
--Andersen PickardSource: Tanner Weber
November 23, 2025
NFL Network's Ian Rapoport reports that the Baltimore Ravens will consider resting quarterback
Lamar Jackson every Wednesday to keep him fresh for the rest of the 2025 season. Jackson missed a few games earlier this year with a hamstring injury and has missed the last two Wednesday practices due to minor ankle and knee injuries. The 28-year-old figures to be a non-participant on Monday, too, but he should be just fine for the Thanksgiving Day game against the division-rival Cincinnati Bengals next Thursday (as long as he comes out of Week 12 without any injuries). Jackson hasn't looked the same on the ground this year, which has kept him from the elite tier of QB1 options in fantasy football. However, the two-time MVP is still a set-and-forget QB1 in fantasy football and could be primed for a bounce-back performance on Sunday against the visiting New York Jets.
--Keith HernandezSource: NFL Network - Ian Rapoport
November 23, 2025
Detroit Lions wide receiver
Isaac TeSlaa (oblique) is officially active for Sunday's Week 12 contest against the New York Giants. He had been listed as questionable after practicing in a limited capacity. The rookie has merely occupied a depth role in his first pro season, catching four of his eight targets for 65 yards and two touchdowns through 10 games. Not only has TeSlaa been operating behind standout receivers
Amon-Ra St. Brown and
Jameson Williams, but he's also been far less involved than
Kalif Raymond. As long as those three pass catchers remain healthy, TeSlaa can be avoided in fantasy football. He should be stashed in dynasty leagues and left on waivers in redraft formats.
--Andersen PickardSource: Tim Twentyman
November 23, 2025
The Pittsburgh Steelers defense will be without linebacker Alex Highsmith (pectoral) for their Week 12 tilt on the road in Chicago against the Bears on Sunday. Highsmith was listed as doubtful coming into this game, and he will officially miss a second straight game. However, the 28-year-old was able to practice in a limited fashion on Thursday and Friday, which means he could return in Week 13 against the Buffalo Bills. With Highsmith out again on Sunday, Nick Herbig and rookie Jack Sawyer will see more reps at linebacker for Pittsburgh. The Steelers' defense hasn't been the lockdown unit that most people are accustomed to seeing, but they will still be in play as a low-end fantasy option this weekend, despite missing Highsmith. Through 11 weeks this year, Highsmith has 24 tackles (15 solo), 5.5 sacks, six tackles for loss, 10 QB hits, and a forced fumble in seven games.
--Keith HernandezSource: Pittsburgh Steelers
November 23, 2025
Tennessee Titans rookie running back
Kalel Mullings (ankle) was activated from Injured Reserve on Saturday and is officially active on Sunday against the visiting Seattle Seahawks in Week 12. Mullings, who was selected in the sixth round in April out of Michigan, will be playing for the first time since injuring his ankle back on Sept. 21 in the loss to the Indianapolis Colts. The 23-year-old wideout will most likely be limited to a special teams role in his return this weekend while also serving as backfield depth behind
Tony Pollard and
Tyjae Spears. He is not a realistic starting option in any fantasy football leagues and probably won't be for the rest of his first year in the NFL. Mullings has only played in two games in 2025 and has not seen a carry or caught a pass on offense for the Titans.
--Keith HernandezSource: Titans PR
November 23, 2025
San Francisco 49ers wide receiver
Brandon Aiyuk (knee) continues to recover from last year's ACL injury, and NFL Network's Mike Garafolo reports that Aiyuk is "close to being cleared" for a return. The receiver's 21-day practice window hasn't been opened yet, but the 49ers remain hopeful that he'll get back on the field in the near future. San Francisco's receiving corps could use the help as
Jauan Jennings and
Ricky Pearsall have been underwhelming, combining for 53 catches, 705 yards, and three touchdowns while managing their respective injuries. Aiyuk could become an instant WR2 or WR3 in fantasy football upon his return, but an exact timetable for his activation remains unclear. This isn't the only news story we've seen about Aiyuk this week, though. A few days ago, Dianna Russini and Michael Silver of The Athletic reported that Aiyuk and the Niners were headed for a "stunning split" after the team voided his 2026 guarantees for a failure to meet contractual obligations, creating a clear path to his release next offseason. While Russini and Silver wrote that Aiyuk has likely played his final game for the 49ers, Garafolo's report seems to clarify that he'll have a good chance to get back on the field in 2025 before the team makes a decision on his future during the offseason.
--Andersen PickardSource: Mike Garafolo
November 23, 2025
Cincinnati Bengals running back
Samaje Perine (ankle), who was listed as doubtful for Sunday's game, is officially out in Week 12 versus the visiting New England Patriots. Perine will be missing a second straight game. The 30-year-old veteran's absence will mean more change-of-pace work for rookie
Tahj Brooks behind starter
Chase Brown, but it won't be enough to make Brooks a standalone option in fantasy lineups this weekend in a tough matchup. It's unclear if Perine will be ready to return on a quick turnaround next week when the team squares off against the division-rival Baltimore Ravens on Thanksgiving Day on Thursday. Perine hasn't been anything more than a deep-league PPR handcuff for those who have Brown rostered. In nine games in 2025, he has 198 rushing yards and one touchdown on 32 carries, adding seven receptions for another 30 yards.
--Keith HernandezSource: Cincinnati Bengals
November 23, 2025
Detroit Lions left tackle Taylor Decker (shoulder) is officially active for Sunday's Week 12 contest against the New York Giants. He had been listed as questionable after missing a pair of practices this past week. Despite the two missed sessions, Detroit's veteran lineman will suit up to help protect
Jared Goff's blindside on Sunday afternoon. In general, the 31-year-old's availability is great news for the entire offense, including running backs
Jahmyr Gibbs and
David Montgomery, in addition to Goff and the rest of the passing game.
--Andersen PickardSource: Paula Pasche
November 23, 2025
Green Bay Packers wide receiver
Savion Williams (foot) is officially active for Sunday's Week 12 contest against the Minnesota Vikings. He was listed as questionable after missing two practices this past week. With
Matthew Golden (shoulder, wrist) sidelined, Williams could push to carve out a larger role behind
Romeo Doubs,
Christian Watson, and
Dontayvion Wicks. The 24-year-old rookie has been dependable when called upon, catching all 10 of his targets for 78 yards and a touchdown through 10 games. Despite his potentially increased workload on Sunday, Williams is still lower on the depth chart and can be left on waivers in most fantasy leagues. He ranks as RotoBaller's WR99 for Week 12.
--Andersen PickardSource: Green Bay Packers
November 23, 2025
Kansas City Chiefs wide receiver
Xavier Worthy (ankle) is officially active on Sunday against the visiting Indianapolis Colts in Week 12, according to Matt McMullen of Chiefs.com. Worthy is dealing with an ankle injury that he suffered in practice back on Nov. 13. The Chiefs listed him as questionable this weekend, but he will be out there as the team looks to avoid falling below .500 on the season. The 22-year-old second-year wideout has taken a back seat in the offense since
Rashee Rice returned from his suspension. Worthy has only found the end zone once this year, too, and it came back on Oct. 12 in the win over the Detroit Lions. Since then, Worthy has gone over 50 receiving yards once in four games. On the year, the Texas product has an uninspiring 27-281-1 line in eight games played. He missed two games earlier this season with a dislocated shoulder.
--Keith HernandezSource: Chiefs.com - Matt McMullen
November 23, 2025
Green Bay Packers wide receiver
Dontayvion Wicks (calf) is officially active for Sunday's Week 12 contest against the Minnesota Vikings. He was listed as questionable after being a limited participant in practice. The 24-year-old should occupy a larger role with rookie receiver
Matthew Golden (shoulder, wrist) ruled out for this divisional battle. Wicks has 18 catches for 181 yards through eight games this season. However, he has come on particularly strong in his last two contests, tallying 10 targets and five receptions during that span. Still, he's off the fantasy radar for now, ranking as the overall WR73 in RotoBaller's Week 12 fantasy rankings.
--Andersen PickardSource: Green Bay Packers
November 23, 2025
Seattle Seahawks running back
Kenneth Walker III (glute) is officially active for Sunday's Week 12 contest against the Tennessee Titans. He had been listed as questionable after popping up on the injury report as a limited participant this past Friday. Despite the last-minute injury scare, Walker will suit up as the Seahawks' primary back. He's coming off an impressive game against the Los Angeles Rams in which he had 16 carries for 67 rushing yards and one touchdown, plus three catches for an additional 44 receiving yards. Amid a relatively inconsistent campaign in which he has shared the workload with
Zach Charbonnet, Walker finds himself as the overall RB23 in fantasy scoring this season. He has a great opportunity to strengthen his fantasy value against a Titans defense that has allowed the fifth-most fantasy points to running backs in 2025. Walker ranks as the overall RB18 in RotoBaller's Week 12 fantasy rankings.
--Andersen PickardSource: Seattle Seahawks
November 23, 2025
New England Patriots running back
Rhamondre Stevenson (toe) is officially active for Sunday's Week 12 contest against the hosting Cincinnati Bengals. Stevenson will return to the Patriots' backfield after a three-game absence due to a toe injury. With the 27-year-old out, rookie
TreVeyon Henderson thrived in the team's lead-back role, scoring five total touchdowns (four rushing, one receiving) while also averaging 88 rushing yards per game. New England has been non-committal on what Stevenson's role will be upon his return. Before getting hurt, Stevenson was operating as the RB1 and had 83 carries for 279 yards and three touchdowns on the ground while adding 169 receiving yards. However, after Henderson's strong performances the last three weeks, Stevenson will likely see his role reduced. Treat him as more of a shaky RB3/flex in his return this weekend.
--Keith HernandezSource: New England Patriots
November 23, 2025
Green Bay Packers wide receiver
Matthew Golden (shoulder, wrist) is officially inactive for Sunday's Week 12 contest against the Minnesota Vikings. He was listed as questionable after being a limited participant in practice. The rookie has been disappointing during his first pro season, catching just 24 passes for 286 yards through nine games. He is also still looking for his first career touchdown. Golden's second absence in three weeks will lead to more opportunities for
Dontayvion Wicks (calf) in his role behind
Christian Watson and
Romeo Doubs.
--Andersen PickardSource: Green Bay Packers
November 23, 2025
Green Bay Packers wide receiver
Matthew Golden (shoulder, wrist) is not expected to play in Sunday's Week 12 contest against the Minnesota Vikings, according to NFL Network's Tom Pelissero. He was listed as questionable after being a limited participant in practice all week long. The rookie has been disappointing during his first pro season, catching just 24 passes for 286 yards through nine games. He's also still looking for his first career touchdown. Golden's absence on Sunday will lead to more opportunities for
Dontayvion Wicks (calf) in his role behind
Christian Watson and
Romeo Doubs.
--Andersen PickardSource: Tom Pelissero
November 23, 2025
Green Bay Packers running back
Emanuel Wilson is expected to start Sunday's Week 12 game against the Minnesota Vikings after
Josh Jacobs (knee) was ruled out for the contest. Jacobs was a game-time decision coming into this weekend, and the Packers ultimately decided to hold him out. Wilson will remain the Packers' primary running back, which is the role he occupied after Jacobs departed last Sunday's game early in the second quarter. The 26-year-old finished that game with 11 carries, 40 rushing yards, and one rushing touchdown, plus a nine-yard reception. The trip to the end zone salvaged his fantasy performance, and he'll look to contribute even more this Sunday with greater volume, more passing-down work, and perhaps more goal-line opportunities. He ranks as a fringe top-24 fantasy running back against a Vikings defense that has allowed the 10th-most rushing yards to running backs in 2025, but the 11th-fewest fantasy points to the position.
--Andersen PickardSource: Tom Pelissero
November 23, 2025
Dallas Cowboys wide receiver
George Pickens is headed for unrestricted free agency next March, but the team wants to bring him back following a career-best season. NFL Network's Ian Rapoport reports that the Cowboys are "more likely" to franchise tag Pickens than allow him to test unrestricted free agency. By tagging him, the team would lock him into a one-year deal worth more than $28 million while gaining the exclusive rights to negotiate a longer-term extension with him. The 24-year-old is worth every penny, catching 58 passes for 908 yards and seven touchdowns in his first season with the Cowboys after being acquired from the Pittsburgh Steelers. He ranks as the overall WR4 in PPR leagues and has complemented
CeeDee Lamb quite nicely in Dallas' high-powered offense.
--Andersen PickardSource: Ian Rapoport
November 23, 2025
Green Bay Packers running back
Josh Jacobs (knee) is inactive for Sunday's Week 12 contest against the Minnesota Vikings, according to Tom Pelissero of NFL.com. Jacobs was listed as questionable and deemed to be a true game-time decision on Sunday morning. In the end, he won't be able to suit up for a key divisional battle at home. Jacobs, who first suffered the injury during the second quarter of last week's game against the New York Giants, will be replaced in the first-team offense by
Emanuel Wilson. Wilson led the Packers' backfield after Jacobs departed last Sunday, tallying 40 rushing yards, nine receiving yards, and one touchdown through the final three quarters. This week, he ranks as a fringe top-24 running back in fantasy football.
Chris Brooks and
Pierre Strong Jr. should also earn some touches in their respective depth roles.
--Andersen PickardSource: Tom Pelissero
November 23, 2025
Pittsburgh Steelers quarterback
Mason Rudolph will earn the start against the Chicago Bears in Week 12 after
Aaron Rodgers (wrist) was ruled out pregame, according to Ian Rapoport of NFL.com. Rodgers was pushing to play, but the team decided to hold him out. This will be Rudolph's first start of the season, but he also earned significant snaps after Rodgers exited last Sunday. In that game, he completed 12 of 16 pass attempts for 127 yards, one touchdown, and zero interceptions. This week, the veteran will face off against a Bears defense that leads the league in interceptions but has also allowed the eighth-most fantasy points to opposing quarterbacks in 2025. He's a low-end QB2 for fantasy purposes.
--Andersen PickardSource: Ian Rapoport
November 23, 2025
Pittsburgh Steelers quarterback
Aaron Rodgers (wrist) won't play in Sunday's Week 12 contest against the Chicago Bears, according to NFL.com's Ian Rapoport. Rodgers was listed as questionable, and although he had "been pushing to play," the team has decided to hold him out. The 41-year-old has been the QB17 in fantasy football this season, completing 66.4% of his passes for 1,969 yards, 19 touchdowns, and seven interceptions.
Mason Rudolph will earn the start in his absence, facing off against a Bears defense that leads the NFL in interceptions but has also allowed the eighth-most fantasy points to quarterbacks in 2025.
--Andersen PickardSource: Ian Rapoport
November 23, 2025
Tampa Bay Buccaneers wide receiver
Chris Godwin (leg) will return to action for just his third game of the season during Sunday's Week 12 contest against the Los Angeles Rams. Godwin reportedly suffered a hairline fibula fracture back in Week 5, resulting in a five-game absence. He's now back in action for Sunday's game and will operate as the Bucs' No. 2 receiver alongside
Emeka Egbuka. Godwin has just six catches for 52 yards across his two healthy games earlier this season, so he'll look to return to his 2024 form from before his season-ending ankle injuries. He was off to an otherworldly start last year, catching 50 passes for 576 yards and five touchdowns over seven games. If Godwin can return to that level of play, he'll be a weekly top-10 receiver in fantasy football. For now, though, he ranks as the overall WR48 in RotoBaller's Week 12 fantasy rankings.
--Andersen PickardSource: RotoBaller
November 23, 2025
Tennessee Titans wide receiver
Chimere Dike should carve out a large role against the Seattle Seahawks in Week 12 after
Elic Ayomanor (hamstring) was ruled out and
Calvin Ridley (leg) was placed on injured reserve for the remainder of the season. Dike has looked like the Titans' best receiver at various times this year, playing 89% and 87% of the snaps in his two games before the bye, respectively. The rookie had two catches on three targets early in last week's game, but a promising start to his Sunday was abruptly cut short due to a chest injury and concussion evaluation. Dike is now healthy again and will return to action as Tennessee's top receiver against Seattle. The Seahawks have defended the pass quite well, allowing the sixth-fewest fantasy points to wide receivers in 2025. However, they've been even better against the run and are heavy favorites against the Titans, so we expect Tennessee to throw quite often. As a result, Dike remains in the mix as a high-volume WR3/flex for Week 12.
--Andersen PickardSource: RotoBaller
November 23, 2025
Cleveland Browns quarterback
Deshaun Watson (Achilles) made his first road trip of the regular season and will be on the sideline for Sunday's Week 12 game against the Las Vegas Raiders, according to Mary Kay Cabot of Cleveland.com. Watson has reportedly offered plenty of help to
Dillon Gabriel (concussion) and
Shedeur Sanders this season, and he worked closely with Sanders to help him understand the game plan before his first NFL start on Sunday. However, Sanders' start isn't the only reason why Watson made the trip. According to Cabot, it's also the first time the veteran quarterback was healthy enough to travel this season. In fact, he could be nearing a return to game action. Watson remains on the PUP list and might have his 21-day practice window activated soon, according to Cabot. The 30-year-old has been sidelined for over a year, but it appears his return could be coming in the near future.
--Andersen PickardSource: Mary Kay Cabot
November 23, 2025
Cleveland Cavaliers guard
Lonzo Ball (knee) will sit Sunday against the Clippers for left knee injury management, extending a rest pattern that has kept him in and out of the rotation. Ball has produced 5.9 points, 4.1 rebounds, and 5.1 assists in 23.3 minutes, with 1.2 steals over his last five games, but his 32.5 percent shooting and ongoing maintenance make him difficult to trust in standard formats. With Ball and
Craig Porter Jr. (hamstring) both out,
Jaylon Tyson and
Tyrese Proctor should see additional ballhandling work behind
Darius Garland, while
Donovan Mitchell remains the primary creator. Ball stays in the mix as an assists-and-steals streamer, though managers should anticipate continued volatility tied to his rest schedule.
--Brian DailisanSource: NBA Injury Report
November 23, 2025
Portland Trail Blazers guard/forward
Shaedon Sharpe (calf) will remain out Sunday in Oklahoma City, marking his third straight absence. Sharpe was averaging 22.6 points, 5.0 rebounds, 2.1 assists, and 1.4 steals in 28.6 minutes before the strain, and the Blazers have replaced his usage with a mix of
Deni Avdija and former Arizona standout
Caleb Love. Love just logged 26 points, seven rebounds, and five assists, while Avdija produced 26 points and 13 assists. Managers should hold Sharpe in leagues with an IR slot, as his scoring and steal output remain valuable, while Love offers short-term stability for managers needing immediate guard production.
--Brian DailisanSource: NBA Injury Report
November 23, 2025
Cincinnati Bengals quarterback
Joe Flacco will get one more opportunity to start after
Joe Burrow (toe) was ruled out for Sunday's Week 12 contest against the New England Patriots. While Burrow was trending in the right direction for this week, the Bengals have ultimately decided to keep him on injured reserve for at least a few more days. As a result, Flacco will remain installed as Cincinnati's starting quarterback for Week 12. He's coming off an uninspiring 199-yard clunker against the Steelers, and although he has five touchdowns over his last two games, he also has four turnovers during that span. To make matters worse, he'll be without
Ja'Marr Chase (suspension), shifting
Tee Higgins to the top receiver role. New England's defense has been strong this season, but it's best at stopping the run. The Patriots have allowed the ninth-most passing yards, seventh-most passing touchdowns, and 12th-most fantasy points to opposing quarterbacks in 2025. This matchup and situation are best defined as "good, not great." That sentiment is reflected in RotoBaller's ranking of Burrow as the overall QB17 this week.
--Andersen PickardSource: RotoBaller
November 23, 2025
Arizona Cardinals wide receiver
Michael Wilson remains atop the depth chart after
Marvin Harrison Jr. (appendix) was ruled out for Sunday's Week 12 contest against the Jacksonville Jaguars. This will be Wilson's second consecutive game as the top wide receiver in Arizona. He dominated last week's contest, catching a whopping 15 of 18 targets for 185 yards. Quarterback
Jacoby Brissett set the NFL's all-time single-game completion record in that outing, so perhaps Wilson's volume will drop a little in Week 12. Still, he's a strong candidate to fetch double-digit targets. He'll also have a decent chance to score his first touchdown since Week 2, especially against a Jaguars defense allowing the eighth-most touchdowns to wide receivers in 2025. Wilson is a strong fantasy starter in most leagues on Sunday, checking in as the overall WR18 in RotoBaller's latest Week 12 fantasy rankings.
--Andersen PickardSource: RotoBaller
November 23, 2025
Atlanta Falcons wide receiver
Darnell Mooney will jump to the top of the depth chart after teammate
Drake London (knee) was ruled out for Sunday's Week 12 contest against the New Orleans Saints. Even as the de facto No. 1 receiver, Mooney's productivity isn't guaranteed. In the other game that London missed earlier this season, Mooney caught just one of four targets for 11 yards. With that said, there's optimism that this week's increased workload will lead to better results. After all, he's already trending up with 15 targets over his last two games. Plus, he gets a softer matchup against the Saints, who rank near the middle of the league in fantasy points and have allowed the eighth-most touchdowns to opposing receivers in 2025. This week, Mooney will be catching passes from
Kirk Cousins, since
Michael Penix Jr. (knee) is on injured reserve. The veteran receiver's game was elevated with Cousins under center last year, as the veteran signal-caller was responsible for most of Mooney's volume and yardage during his 64-catch, 992-yard campaign in 2024. Managers should feel comfortable starting the 28-year-old as a WR3/flex this week. He ranks as the overall WR26 in RotoBaller's latest fantasy rankings for Week 12.
--Andersen PickardSource: RotoBaller
November 23, 2025
Portland Trail Blazers guard
Jrue Holiday (calf) will miss at least 1-2 weeks with a right calf strain, extending an absence that has already reached four games. The veteran was producing 16.7 points, 5.3 rebounds, 8.3 assists, and 1.6 steals in 33.4 minutes on 44.6 percent shooting before the setback. His absence forces Portland to lean heavily on
Deni Avdija for initiation, while
Caleb Love gains the clearest path to minutes and shot volume.
Sidy Cissoko also becomes a deeper-league consideration with multiple starters sidelined. Holiday remains a firm hold in all competitive formats, but shallow-league managers may need to evaluate IL constraints until he is cleared.
--Brian DailisanSource: NBA Injury Report
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