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Cleveland Browns quarterback Deshaun Watson (shoulder) will not play in Week 6 against the undefeated San Francisco 49ers on Sunday, according to a source. Watson missed another day of practice on Thursday and is set to miss his second straight game due to a rotator-cuff contusion in his right shoulder that he sustained in Week 3. The 28-year-old missed Week 4 and still isn't ready to suit up after a bye in Week 5. Watson's absence is once again a huge downgrade for all of Cleveland's offensive skill players in fantasy, most notably receiver Amari Cooper. Rookie Dorian Thompson-Robinson made his first career start in Week 4, but the Browns will go with P.J. Walker this time around. The 49ers defense could feast in Week 6.--Keith Hernandez
Source: CBS Sports - Josina Anderson
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REAL-TIME FANTASY NEWS

Jared McCain

on Track to Make Season Debut Tuesday
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Has Multi-Point Outing Monday
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Notches Three Points in Overtime Victory
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Continues Home Success Monday
Connor McDavid

Surpasses 1,100 Career Points
Auston Matthews

Sparks Maple Leafs Comeback
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Sustains Upper-Body Injury
Atlanta Braves

Braves Hire Walt Weiss as Their Next Manager
Kris Bubic

Cleared to Begin a Throwing Program
Brandon Woodruff

Declines Mutual Option for 2026
Freddy Peralta

Brewers Exercise 2026 Option on Freddy Peralta
Lucas Giolito

Declines his 2026 Player Option
Daniel Gafford

to be Limited on Monday
Jabari Smith Jr.

Sidelined on Monday Night
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Available to Play on Monday
Walker Kessler

Out Again on Monday Night
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Unavailable on Monday
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Officially Inactive on Monday Night
Johnny Furphy

Ready to Go on Monday
RayJ Dennis

Cleared for Monday
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Available on Monday
Dylan Harper

to "Miss Multiple Weeks"
J.J. Spaun

Finishes Sixth at Procore Championship
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Finishes Tied for 10th at Baycurrent Classic
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Finishes Tied for 56th at Baycurrent Classic
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Finishes Tied for 56th at Bank of Utah Championship
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Ready for Season Debut Tuesday
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to Miss "Extended Period of Time"
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Not Expected to Return to Practice Until After Week 12 Bye
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Set to Return Monday
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Luka Doncic Sitting Out On Monday
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to Play Monday Despite Questionable Tag
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Dennis Schroder Available for Kings on Monday Night
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Opts Out of his Contract With Boston
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Edwin Diaz on the Open Market This Winter
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Becomes Free Agent After Opting Out
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Opts Out, Becomes Free Agent
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Concludes the 2025 Season with A Win at Phoenix
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Done for the Year With Torn ACL
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Scores First-Round TKO Win
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Dylan Raiola Suffers Season-Ending Injury
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Remains Undefeated
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Gets Dealt to Eagles for a Third-Round Pick
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Still Winless In The UFC
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Dominates Daniel Frunza
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Stays Hot on Sunday
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