DraftKings NFL DFS Picks for Week 3 - Top Plays, Value Picks, Lineup Advice for Main Slate (2025)

September 19, 2025

Jamie's DraftKings NFL DFS Week 3 picks, value plays, DFS sleepers for the main slate (2025). His top DK plays and value picks for daily fantasy football lineups.

Did you survive the madness of Week 2, RotoBallers?? How about that Giants-Cowboys game that featured 77 points and 984 yards of total offense? There were several other explosions (hi, Detroit) and another week of worry for some players (where have you gone, Brian Thomas Jr.?). With my cash lineup and Lions stacks in GPP, I had a lucrative week.

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DraftKings Quarterbacks - Week 3 DFS Picks

TOP PLAY

Caleb Williams, CHI vs. DAL ($5,600)

This is a HIGHLY unusual week where the "high-end" quarterbacks aren't at all necessary. You'll obviously want to give them a look in GPPs, but Caleb Williams' price tag is about the limit you have to reach for in most contests. In addition, Williams has the matchup and the potential volume to match those top guys in raw score.

Williams is currently the QB9 in fantasy through the first two weeks with 21.1 FPPG, and there are encouraging signs that he's going to take that next step. Williams has thrown the ball 65 times and rushed 11, and his efficiency has been solid. This week, he gets a Dallas squad that looks like the team to attack.

Last week, Russell Wilson was the QB, Malik Nabers was the WR2, and Wan'Dale Robinson was the WR8. This was all against a Dallas defense that traded away Micah Parsons and now doesn't have DaRon Bland, either. Chicago has beefed up its offensive line to protect Caleb and company, and Rome Odunze looks like a legit WR1.

If you're not dipping ALL the way down to Carson Wentz (see below), Williams is carrying the ownership and upside for cash.

VALUE PLAY

Carson Wentz, MIN vs. CIN ($4,000)

For the second week in a row, we have a bottom-priced QB who is more than usable in all formats. Mac Jones had enough talent and supporting cast in Week 2 to provide more than enough value, and Carson Wentz would seem to be in the same boat here. Even without Aaron Jones Sr. (also out this week), Wentz is surrounded by weapons.

The only real question is if you'll want to pair Wentz with Jordan Mason, who will likely be the most-owned player on the slate and rightfully so. With Jones out, Mason should see enough of the passing work that Wentz won't cannibalize his value. The matchup is prime, as Cincinnati allowed 25.5 PPG last year, and its defense projects to be terrible all year.

Other options - Justin Herbert, Dak Prescott, Drake Maye

DraftKings Running Backs - Week 3 DFS Picks

TOP PLAY

Bijan Robinson, ATL @ CAR ($7,900)

It looks like I'm against the grain with this pick, as Christian McCaffrey seems like the consensus top choice again. I want Bijan Robinson, though, who gets the dream matchup against Carolina, which is one he's already more than exploited. Last year, Robinson absolutely trucked the Panthers for 43/265/4 (6.2 YPC).

Just want to let yall know ... Bijan Robinson gets the Panthers next week pic.twitter.com/hHYkA4Kc7i

— Michael F. Florio (@MichaelFFlorio) September 16, 2025

Carolina's defense against the run is no better this year, as it has already allowed 5.7 YPC. Robinson is a volume monster who's already averaging 21.5 touches and 146 YPG, and the Tyler Allgeier TD should cause you no worry. If you really like McCaffrey and are torn, Wentz allows for both!

VALUE PLAY

Jordan Mason, MIN vs. CIN ($5,400)

Jordan Mason to the moon! He was already showing out as the better runner in Minnesota, and now Jones will be out for at least the next four games. Mason sets up for an every-down role, and is simply not priced that way when you look at his counterparts in that range.

This is the perfect matchup, as Cincinnati has already allowed the second-most FPPG to RBs. Mason is fourth in missed tackles forced per attempt, and getting Christian Darrisaw back on the line is going to be a HUGE difference. Mason has 20-25 touch upside in this one, and is a cash lock and someone you should be overweight on in GPP.

Other options - Christian McCaffrey, Jonathan Taylor, Jaylen Warren

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DraftKings Wide Receivers - Week 3 DFS Picks

TOP PLAY

Jaxon Smith-Njigba, SEA vs. NO ($6,500)

We all knew Jaxon Smith-Njigba's 57% target share and 91% air yards share in Week 1 were beyond unsustainable, but that doesn't mean he's not a WR1 this year. He still had a 30.3% target share in Week 2 and parlayed it into an 8-103-0 day on nine targets.

JSN's price tag has risen $500 since last week, and $700 since Week 1. That's not near enough, however, as his weekly floor/ceiling combination should be well into the $7K range. New Orleans is not a formidable defense, and Smith-Njigba should feast again. Can he sustain a 42% target share? No, but he's a high-end WR1. Both things can be true.

VALUE PLAY

Rome Odunze, CHI vs. DAL ($5,300)

It looks like the Bears have found their new WR1 in Rome Odunze, and he's a perfect pairing with Williams against Dallas. Odunze is already at 13/165/3 on 20 targets and is seventh in the NFL in air yards through two weeks. DJ Moore is only at 8/104/0 and is still priced ahead of Odunze.

Rome Odunze's second TD today! @ChicagoBears

CHIvsDET on FOX/FOX Onehttps://t.co/HkKw7uXVnt pic.twitter.com/j37eTa8tjV

— NFL (@NFL) September 14, 2025

Williams and Odunze will get to take shots at the aforementioned Dallas defense, which gave up one big play after another last Sunday against the Giants. The Bears have a slate-high implied team total of 26 points after the Cowboys gave up 506 total yards to the Giants. Grabbing Chicago exposure is the right path in all formats.

Other options - Puka Nacua, Jakobi Meyers, Keenan Allen

DraftKings Tight Ends - Week 3 DFS Picks

TOP PLAY

Trey McBride - ARI @ SF ($5,700)

Trey McBride checks in as my top TE stud for the third week in a row. Two weeks in, and we're still waiting for that TD spike we've been calling for last year. After scoring only two TDs all of last year, McBride has still been kept out of the end zone this season despite having a 25.8% target share on a 96.7% snap rate.

San Francisco is generally a tough defense against TEs, and it is better than average so far this season. However, this projects as a back-and-forth game with the injuries to San Francisco on offense, and McBride is a target monster. There are cheaper guys for cash, but McBride's price tag dropped $300 on DK, which makes him perfect for GPPs.

VALUE PLAY

Juwan Johnson, NO @ SEA ($3,900)

I had a real dilemma between Juwan Johnson and Harold Fannin Jr. last week as my "best cheap TE." I had Johnson projected more, but ultimately decided to eat the chalk on Fannin. Johnson did wind up outscoring him, but it didn't hurt me (plus the extra money would have cost me Amon-Ra St. Brown, which would have been catastrophic).

This week, I have no issue calling Johnson the best value, even if he costs a little more money than Fannin. Johnson has 21 targets and 144 air yards through the first two weeks, both of which lead all tight ends. He should not be priced under $4K, and his savings allow you big-time studs at the skill positions. Seattle has also allowed the second-most FPPG to TEs, and the Saints should be playing from behind.

Other options - Tucker Kraft, Tyler Warren, Harold Fannin Jr.

DraftKings D/ST - Week 3 DFS Picks

Top 5 Defenses For Cash Games

1. Pittsburgh Steelers ($2,800)
2. Atlanta Falcons ($3,200)
3. Green Bay Packers ($3,700)
4. Cleveland Browns ($2,200)
5. Jacksonville Jaguars ($2,800)

Thanks for reading, and good luck in your contests this weekend!

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