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Fantasy football rankings and Thursday Night Football injury updates for Week 16 of the 2021 NFL season including Dalvin Cook, Alexander Mattison and more.
Week 16 is here RotoBallers -- the fantasy football playoff semi-finals in most leagues. In this article you will see our early fantasy football rankings for Week 16. The Thursday Night Football matchup kicks things off tonight, so make sure to set your optimal lineups!
There are once again many injuries and COVID issues to deal with that will affect our fantasy football rankings. For those who are not familiar, three of RotoBaller's lead fantasy football analysts - Nick Mariano, Pierre Camus and Brandon Murchison - put together their constantly-updated rankings each week, and you will find those rankings below.
Before the rankings, below you will find a running list of significant fantasy football injuries and COVID updates. Be sure to check back throughout the week, and good luck in Week 16 RotoBallers!
Be sure to check all of our fantasy football rankings for 2025:- 2025 fantasy football rankings
- Running back (RB) fantasy football rankings
- Wide receiver (WR) fantasy football rankings
- Tight end (TE) fantasy football rankings
- Quarterback (QB) fantasy football rankings
- Defense (D/ST) fantasy football rankings
- NFL rookie fantasy football rankings
- Best ball fantasy football rankings
- Superflex fantasy football rankings
- Dynasty fantasy football rankings
Week 16 Fantasy Football Injury Report
- Dalvin Cook Placed On COVID-19 List, Will Not Play
- Taysom Hill On COVID List, Ian Book To Start Monday
- Austin Ekeler Placed On The COVID-19 List
- Brandin Cooks Placed On COVID-19 List
- Elijah Mitchell Ruled Out For Thursday's Game
- D'Andre Swift Returns To Practice
- Tyreek Hill Headed To COVID-19 List
- Joe Mixon Battling Sprained Ankle Ahead Of Week 16
- Travis Kelce Lands On COVID-19 List
- Jared Goff Lands On COVID-19 List
- Packers Put Marquez Valdes-Scantling On COVID-19 List
- Buccaneers Signing Le'Veon Bell
- Leonard Fournette May Go On Injured Reserve
- Austin Hooper Back From COVID-19 List
- Kareem Hunt Not Expected To Play On Christmas Day
- Lamar Jackson Misses Another Practice
- D.J. Moore Likely To Be Game-Time Decision In Week 16
- Taylor Heinicke Clears COVID-19 Protocols, Returns To Practice
Week 16 Rankings for Fantasy Football
You can also see our Week 16 ranks for PPR and Half-PPR scoring.
Last updated on Thursday 12/23 at 12:30 pm ET:
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More Weekly Lineup Prep
Check out all of RotoBaller's fantasy football rankings. Staff rankings are updated regularly for all positions and include standard formats, PPR scoring, tiered rankings and dynasty leagues.
