September 7, 2025
Indianapolis Colts quarterback
Daniel Jones completed 22 of his 29 pass attempts for 272 yards, one touchdown, and zero interceptions during Sunday's Week 1 victory over the Miami Dolphins. He also added 26 rushing yards and two rushing touchdowns. The former first-round pick played clean, turnover-free football and took just one sack in his Colts debut. Some of his productivity may have been aided by a matchup against Miami's poor defense, but it's also possible that Jones is embarking on a career resurgence in Indianapolis. He'll get a much tougher test next week when he faces the Denver Broncos. Heading into Week 2, Jones ranks as a mid-to-low QB2 option in fantasy football.
--Andersen PickardSource: RotoBaller
September 7, 2025
Los Angeles Rams tight end
Colby Parkinson (shoulder) returned during the second quarter of Sunday's Week 1 contest against the Houston Texans. Parkinson had briefly exited the contest and was listed as questionable, but he was able to check back into the contest shortly thereafter. So far, he is the only Rams tight end with a reception, but he figures to face some positional competition from
Tyler Higbee and
Terrance Ferguson going forward.
--Andersen PickardSource: Nate Atkins
September 7, 2025
Los Angeles Rams wide receiver
Puka Nacua (head) returned to Sunday's game after being evaluated for a concussion. Nacua was on the receiving end of a head-to-head hit that left him bleeding, but he cleared the mandatory concussion check and was able to get back into the game. His return puts the Rams' offense at full strength. He and
Davante Adams will continue to form one of the NFL's best wide receiver tandems, providing significant passing game support to
Matthew Stafford in Week 1 and beyond. Nacua and Adams both have top-15 upside at the wide receiver position in fantasy football.
--Andersen PickardSource: Sarah Barshop
September 7, 2025
Los Angeles Rams tight end
Colby Parkinson (shoulder) exited during the first half of Sunday's Week 1 contest against the Houston Texans. He is questionable to return. At the time of his departure, he had been targeted just once, resulting in a one-yard reception. Parkinson's injury comes at a time when the Rams couldn't afford to lose another pass-catcher. Moments earlier,
Puka Nacua (head) exited to be evaluated for a concussion.
Davante Adams remains
Matthew Stafford's top target with Nacua and Parkinson sidelined, while players like
Tyler Higbee and
Tutu Atwell should also see additional opportunities in the passing game.
--Andersen PickardSource: Los Angeles Rams
September 7, 2025
San Francisco 49ers tight end
George Kittle (hamstring) has been ruled out for the remainder of Sunday's Week 1 contest against the Seattle Seahawks. At the time of his departure, he had caught four passes for 25 yards and one touchdown. The star tight end is one of the focal points of San Francisco's offense, and he has been able to stay relatively healthy, missing just two games in 2024. His injury represents a major concern for the Niners in Week 1 and beyond. Fantasy managers should monitor Kittle's practice status next week, as it's too early to tell whether this might be a multi-week absence.
Luke Farrell will operate as the 49ers' primary tight end until Kittle can return.
--Andersen PickardSource: Field Yates
September 7, 2025
Los Angeles Rams wide receiver
Puka Nacua (head) was taken to the locker room to be evaluated for a concussion during the first quarter of Sunday's Week 1 contest against the Houston Texans. He is questionable to return. The injury appeared quite serious as Nacua had blood running down his face after taking a hit to the head from Henry To'oTo'o. At the time of his departure, Nacua had four targets, three catches, and 23 receiving yards. When healthy, he is a low-end fantasy WR1 in fantasy football.
Davante Adams will operate as
Matthew Stafford's primary target with Nacua sidelined, while
Colby Parkinson,
Tyler Higbee, and
Tutu Atwell also get involved in the passing game.
--Andersen PickardSource: Adam Grosbard
September 7, 2025
Tennessee Titans running back
Kalel Mullings (ankle) exited during the first quarter of Sunday's game against the Denver Broncos. He is officially questionable to return. The rookie had not registered a statistic prior to his departure. Mullings entered this weekend listed as questionable with an ankle injury, so it's possible that he re-aggravated an existing ailment. With
Tyjae Spears (ankle) on IR and Mullings sidelined for the moment, Tennessee's only healthy running backs are
Tony Pollard and
Julius Chestnut.
--Andersen PickardSource: Chris Tomasson
September 7, 2025
Las Vegas Raiders tight end
Brock Bowers (knee) told NFL Network's Tom Pelissero that he's fine and has no concerns about his injury going forward. The star tight end originally exited Sunday's game against the Patriots with a knee injury and was listed as questionable, but it sounds like he won't have any lingering effects going forward. Bowers finished Week 1 with eight targets, five catches, and 103 yards. He'll rank as a high-end TE1 heading into Week 2 against the Los Angeles Chargers. In two games against the Chargers last year, Bowers totaled 10 catches, 108 yards, and one touchdown.
--Andersen PickardSource: Tom Pelissero
September 7, 2025
Atlanta Falcons wide receiver
Drake London (shoulder) exited during the fourth quarter of Sunday's Week 1 contest against the Tampa Bay Buccaneers. He is officially questionable to return. At the time of his departure, he had caught eight of 15 targets for 55 yards. The Falcons were already playing without
Darnell Mooney (shoulder), so London's exit from the contest is a loss that Atlanta cannot afford.
Ray-Ray McCloud III,
Kyle Pitts Sr., and
Bijan Robinson will operate as
Michael Penix Jr.'s primary targets until London can return.
--Andersen PickardSource: Tori McElhaney
September 7, 2025
Minnesota Vikings safety Harrison Smith (illness) has been downgraded to out ahead of Monday Night Football against the Chicago Bears. Smith had been listed as doubtful after logging a limited practice on Friday. He will not travel with the team. The 36-year-old will have to wait at least one more week before kicking off his 14th NFL season. He made 16 starts last season, totaling 87 tackles, three interceptions, one fumble recovery, and one sack. Theo Jackson and Jay Ward should earn more defensive snaps in Smith's absence.
--Andersen PickardSource: Minnesota Vikings
September 7, 2025
New Orleans Saints wide receiver
Chris Olave (chest) exited during the fourth quarter of Sunday's Week 1 contest against the Arizona Cardinals. The team announced that he was questionable, but he quickly returned to the contest. Olave will re-assume his role as the Saints' No. 1 wide receiver ahead of
Rashid Shaheed. Given his role in a subpar
Spencer Rattler-led offense, Olave should merely be viewed as a high-end WR3/FLEX option in fantasy football.
--Andersen PickardSource: New Orleans Saints PR
September 7, 2025
Las Vegas Raiders tight end
Brock Bowers (knee) exited during the fourth quarter of Sunday's Week 1 contest against the New England Patriots. He is officially listed as questionable to return. The star second-year tight end was seen entering and exiting the medical tent, and he eventually returned to the sideline wearing his helmet. At the time of his departure, Bowers had caught five of his eight targets for 103 yards. Fantasy managers should continue to monitor for updates on the consensus TE1 in this year's drafts. For the time being,
Michael Mayer will operate as the Raiders' No. 1 tight end.
--Andersen PickardSource: Las Vegas Raiders
September 7, 2025
Indianapolis Colts running back
Jonathan Taylor (undisclosed) exited Sunday's game against the Miami Dolphins and was seen chatting with medical personnel on the sideline, according to Kevin Bowen of 1075 The Fan. After playing 100 percent of the offensive snaps in the first half, Taylor was not on the field for a scoring drive in the fourth quarter of Week 1. The severity of Taylor's injury is unknown, and it's possible that the Colts are being extra cautious with his management because they are leading by four possessions in the final quarter. Nevertheless, fantasy managers should continue to monitor his status. At the time of Taylor's departure, he had 18 carries for 71 rushing yards, plus 27 receiving yards.
D.J. Giddens has been handling backfield snaps in his absence.
--Andersen PickardSource: Kevin Bowen
September 7, 2025
Tennessee Titans running back
Kalel Mullings (ankle) is officially active for Sunday's Week 1 contest against the Denver Broncos. He had been listed as questionable after logging a limited practice session on Friday. The Michigan product rushed for 948 yards and 12 touchdowns during his final collegiate season last year. Although he was drafted as the Titans' projected No. 4 running back, he will carve out a larger role for the time being with
Tyjae Spears (ankle) on injured reserve. Mullings and
Julius Chestnut will likely rotate in as the backup options behind clear-cut starter
Tony Pollard on Sunday afternoon.
--Andersen PickardSource: Turron Davenport
September 7, 2025
San Francisco 49ers running back
Jordan James (finger) is officially inactive for Week 1 against the Seattle Seahawks. He had been listed as doubtful after logging three consecutive limited practices. James will have to wait at least one more week before making his NFL debut. The Oregon product was an effective runner in college, totaling 1,476 yards and 15 touchdowns during his final collegiate season. For now, San Francisco will operate with
Brian Robinson Jr. and
Isaac Guerendo in depth roles behind
Christian McCaffrey.
--Andersen PickardSource: Rob Lowder
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