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FanDuel MLB DFS Lineup Picks (6/25/21): Daily Fantasy Baseball Advice

juan soto fantasy baseball rankings outfield MLB injury news

Juan Carlos Blanco highlights the top FanDuel MLB DFS lineup picks for 6/25/21, and a couple of sleepers to consider while building daily rosters.

FanDuel’s main slate Friday features 13 games, as there are two afternoon games and Game 2 of the Phillies-Mets doubleheader is also off the slate. However, we naturally have plenty of choices to work on both the pitching and hitting side, even though there are only a handful of what could be considered aces in action.

Salaries are such that it’s possible to put together a lineup that exploits some of the numerous advantageous matchups/venues while still rolling out a solid pitcher.

I'll be providing you with my daily fantasy baseball lineup picks for the FanDuel main slate on 6/25/2021. Be sure to also check out all the MLB player news, including late scratches, and the projected and confirmed daily MLB lineups for each DFS slate. You can also read more DFS advice and lineup picks for sites like DraftKings, and other sports.

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FanDuel DFS Pitchers

Cash Game/GPP Anchor Play:

Carlos Rodon – vs. SEA ($11,200)

Rodon carries the highest salary on the slate for good reason, considering he’s averaging 46.3 FD points and has posted 46 to 61 FD points in four of the last six starts alone. The left-hander has also allowed either one or zero earned runs in five of his trips to the mound during that sample, and he owns a 1.99 ERA, 0.73 WHIP and 0.6 HR/9 across 31.2 innings at home. The Mariners came up empty and produced just two hits while striking out nine times against Rodon back on Opening Day, and Seattle comes in with a .304 wOBA and -0.9 wRAA against lefties on the road in the last month.

Potential Alternate Play

Jon Lester – at MIA ($6,900)   

Lester still has his usual trouble with both location and the long ball on occasion, but he’s been solid thus far in DC with a 3.96 ERA. He’s also coming into Friday’s matchup with plenty of steam, as he owns a 2.55 ERA over the 24.2 innings covering his last five starts. The veteran southpaw has been more hittable on the road and has allowed a bloated 3.1 HR/9 when traveling, but the Marlins don’t exactly shape up as the type of team that can exploit that. Miami checks in with a 28.4 percent strikeout rate, .213 average, .269 OBP, -5.8 wRAA and MLB-low .257 wOBA, along with an anemic 72 wRC+, against left-handers at home over the last month.

ALSO CONSIDER: Sean Manaea ($9,400)

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FanDuel DFS Infielders

Max Muncy- 1B, vs. CHC ($3,900)

Muncy went into Thursday’s no-hit loss to the Cubs with a .266 average and .954 OPS, as well as a .292 average and 1.077 OPS over 124 plate appearances at Dodger Stadium. The lefty-swinging slugger will take aim at a familiar target in Jake Arrieta on Friday, who he’s touched up for a .400 average and a pair of homers in 10 career encounters. The success isn’t surprising, considering Arrieta has allowed a .310 average, .989 OPS and .412 wOBA to left-handed hitters on the road. Meanwhile, Muncy has eviscerated right-handed pitching at home, where he’s battered that handedness for a 1.033 OPS, .435 wOBA and .302 ISO.

Marcus Semien – 2B, vs. BAL ($4,100)

The Blue Jays get the gift of facing Matt Harvey in their hitter-friendly home park Friday, meaning rolling out a stack of their right-handed bats certainly wouldn’t be a bad idea. In this case, I’ll spotlight Semien, who’s tallied a .917 OPS, .391 wOBA, .280 ISO and 148 wRC+ against right-handed pitching at home. Harvey makes about the perfect target for him, as the quickly fading right-hander has given up a .373 average, .887 OPS and .383 wOBA to right-handed hitters on the road, and a .413 wOBA to that handedness overall. Semien also has an .890 OPS at home, enhancing his already strong case.

Abraham Toro– 3B, at DET ($2,500)

Toro’s season slash line now sits at a rock-solid .282/.378/.436 following a pair of walks over three plate appearances in Thursday’s blowout win over the Tigers, and he makes for an excellent value consideration Friday against a highly vulnerable pitcher in Wily Peralta. The 32-year-old right-hander allowed five earned runs, including two homers, in his first start of the season against the Angels on Saturday. Peralta has given up a .375 average and .669 wOBA to the nine left-handed hitters he’s faced thus far this season, and a .278 average and .363 wOBA over his much larger career sample. In the meantime, Toro has hit both his homers off right-handed pitching this season and owns a .504 wOBA against the four-seam fastball, which is Peralta’s most often-thrown pitch in this season’s small sample.

Wander Franco – SS, vs. LAA ($3,000)

Franco reached safely in his first two games before going 0-for-4 with three strikeouts in Thursday’s 1-0 win, but there’s no doubting the phenom’s prodigious ability. The switch-hitting Franco was tormenting pitchers of either handedness at Triple-A Durham to the tune of a .315/.367/.586 slash line before his promotion. Angels starter Griffin Canning has struggled against left-handed hitters on the road, as he’s given up a .289 average, .847 OPS and .373 wOBA in that split.

 

FanDuel DFS Outfielders

Adolis Garcia– vs. KC ($3,500)

Garcia has been a breakout star, as he’ll enter Friday’s matchup with 28 XBH, 52 RBI and an .846 OPS. The slugging outfielder has been better against right-handed pitching, but he’s still tagged southpaws for eight extra-base hits, including seven home runs, over 23 total hits versus that handedness. He also boasts a .354 wOBA and .288 ISO at home, and Royals starter Mike Minor has given up 13 of his 14 homers on the season to righty bats, leading to a 1.6 HR/9 in that split. The Royals bullpen could also be good targets for Garcia once Minor exits, considering they’ve allowed a .330 wOBA to right-handed hitters in June.

Juan Soto- at MIA ($3,800)

Soto has a tough matchup on paper against Marlins right-hander Pablo Lopez, who has an impressive 2.86 ERA, including a 1.89 ERA, .192 BAA and .246 wOBA at LoanDepot Park. Nevertheless, it’s a matchup Soto has conquered before, as he’s punished Lopez for a .471 average, three doubles and five home runs across 21 career encounters. Additionally, Soto has been absolutely lethal against right-handed pitching, furnishing a .354 average and .432 wOBA against that handedness on the road, along with a 41.7 percent HR/FB rate and 45.2 percent hard-contact rate in that split.

Whit Merrifield – at TEX ($3,600)

Merrifield makes for an interesting option against Rangers starter Dane Dunning, who’s allowed a .294 average, .347 wOBA and 1.5 HR/9 to right-handed hitters. Merrifield boasts a .322 average, .812 OPS and .348 wOBA in June, along with a stellar 25.4 percent line-drive rate. Merrifield also happens to do very well against Dunning’s trademark sinker, as he’s posted a .391 wOBA against the pitch this season (and a .439 one for his career) while Dunning has given up a .360 wOBA when throwing the pitch this season.

ALSO CONSIDER: Tommy Pham ($3,400)



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REAL-TIME FANTASY NEWS

Cade Cunningham

Ready to End Two-Game Absence
Devin Booker

Questionable for Thursday Night
Giannis Antetokounmpo

Probable to Face Spurs
Brandon Williams

Available Wednesday
Max Christie

Out Wednesday
P.J. Washington

Returns to Action Wednesday
Scotty Pippen Jr.

Season Debut Delayed for at Least Four More Weeks
Brandon Clarke

to Miss 4-6 More Weeks
Josh Giddey

Starting Ramp-Up Period, Could Return Soon
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Unavailable Thursday
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Out Wednesday
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to Be Limited to 28-30 Minutes Wednesday
Paul George

Active Against Cavaliers
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Cleared to Play Wednesday
Kelly Oubre Jr.

Available Wednesday
VJ Edgecombe

Active Versus Cavs
Herbert Jones

Misses Wednesday's Action
Christian Braun

Out Wednesday
Sandro Mamukelashvili

Out Versus Pacers on Wednesday
Ivica Zubac

Won't Play Wednesday
Lauri Markkanen

Misses Wednesday's Game Due to Illness
Mackenzie Blackwood

Activated From Injured Reserve
Ben Griffin

Looks To Stay Hot In 2026
Tom Wilson

Cleared for Contact, Could Return Thursday
Neal Pionk

Lands on Injured Reserve, Out Week-to-Week
Jamie Drysdale

Activated From Injured Reserve
Corey Perry

Unavailable Wednesday
Teuvo Teravainen

to Miss at Least One Game
Connor Bedard

Returns to Practice
Alexandre Texier

Canadiens Sign Alexandre Texier to Two-Year Extension
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Giants Making "Massive Push" to Hire John Harbaugh on Wednesday
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Expected to Play More Defense in 2026
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FBS Coaches Unanimously Vote to Expand Redshirt Eligibility to Nine Games
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Ohio State Transfer Mylan Graham Signs with Notre Dame
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Caden Durham Withdraws from Transfer Portal, Will Stay at LSU
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Jordan Spieth

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Chandler Stephenson

Available Wednesday
Aaron Rai

Looking For Putting Confidence at Waialae Country Club
Jonathan Marchessault

Moved to Injured Reserve
Brayden Point

Labeled Week-to-Week
Collin Morikawa

Isn't The Safe Play He Used to Be Ahead of Sony Open
Kurt Kitayama

Needs His Putting to Turn Around For Success at Year's First Event
Ryan Weathers

Yankees Add Rotation Depth, Acquire Ryan Weathers in Four-Player Deal
Robert Thomas

Out Tuesday
Jake Walman

Available Against Predators
Troy Terry

a Game-Time Decision Tuesday
Justin Sourdif

Won't Play Tuesday
Jakob Chychrun

a Game-Time Call Tuesday
Morgan Geekie

Available Tuesday
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Chargers Fire Offensive Coordinator Greg Roman
Pittsburgh Steelers

Mike Tomlin Stepping Down as Steelers Head Coach
CFB

Georgia Tech the Favorite to Land Justice Haynes?
Nolan Arenado

Cardinals Trade Nolan Arenado to Diamondbacks
Tom Kim

Desperately Needs a Solid Week at Sony Open
Billy Horschel

Hoping For a Fast Start to New Season at Sony Open
Corey Conners

Looks to Have a Return to Form in 2026
PGA

Chris Gotterup a Decent Play at Sony Open
Gary Woodland

Could Prosper at the Sony Open
Keith Mitchell

Unlikely to Contend at Sony Open
Robert MacIntyre

Looking for a Good Performance at the Sony Open
Michael Kim

Hopes to Start Sony Open Better This Week
Tom Hoge

Tries to Erase Poor 2025 Second Half in Hawaii
Brian Harman

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Looks to Last Year for Success at Sony Open
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Carted to Locker Room for Concussion Evaluation
Kyle Tucker

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Tucker Kraft

Hopes to be Ready for Week 1 of Next Season
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Georgia Lands Kentucky Transfer Dante Dowdell
Matthew Stafford

has "Little Sprain," Should be "Good to Go"
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Sam Leavitt Expected to Sign with LSU
Green Bay Packers

Packers Expected to Work Out New Deal With Matt LaFleur in the "Coming Days"
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Dylan Raiola Commits to Oregon
CFB

Isaiah Horton Landing with Texas A&M
George Kittle

Suffers Torn Achilles on Sunday
Omarion Hampton

Active for Wild-Card Round Against Patriots
George Kittle

Ruled Out After Non-Contact Achilles Injury
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Raiders Request Interview With Ejiro Evero
Los Angeles Rams

Mike LaFleur to Interview With Raiders and Cardinals
Aaron Rodgers

Steelers Open to Re-Signing Aaron Rodgers?
Matthew Stafford

X-Rays Come Back Negative
MacKenzie Gore

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Alex Bregman

Cubs Sign Alex Bregman to Five-Year, $175 Millon Contract
Freddie Freeman

Withdraws from World Baseball Classic
Max Kepler

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Cam Coleman Visiting Alabama on Friday
Omarion Hampton

Expects to Play Sunday Night
CFB

Eric Singleton Jr. Enters Transfer Portal, Trending to Land at Florida
CFB

NCAA Denies Trinidad Chambliss a Sixth Year of Eligibility
Omarion Hampton

Questionable for Wild-Card Weekend
Kyle Tucker

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Ketel Marte

Will Remain With Diamondbacks
Rashee Rice

to be Reviewed Under League's Conduct Policy

RANKINGS

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RB
WR
TE
K
DEF
RANKINGS
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1B
2B
3B
SS
OF
SP
RP