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DraftKings Daily Fantasy Baseball Picks (8/21/18): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on August 21st, 2018. Tom Vecchio's MLB DFS analysis and sleepers for building optimal DFS rosters.

We have a monster 15-game slate to break down today, and there are some great options across the board. There are a few high-priced pitchers on the slate you should be looking to pay up for, along with plenty of bats you want to jam into your lineups.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 8/21/18. The lineup picks will range from some of the elite players to mid-priced options and value plays.

You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @DFS_Tom.

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DraftKings DFS Starting Pitchers

Jose Berrios – P, MIN @ CWS (DK - $10,900)

Berrios is one of the more expensive pitchers on today’s slate, but he comes in with a very favorable matchup, so he’s worth spending up for. Tonight, he faces off against the Chicago White Sox, who come in with a 25.8% strikeout rate vs right0handed pitchers this season, which is dead last in the league. Berrios has faced the White Sox three times this season, with a total of 22 innings pitched, 23 strikeouts and has only allowed six earned runs.

Masahiro Tanaka – P, NYY @ MIA (DK - $10,200)

Tanaka is up against the Marlins tonight, who come in with a team wOBA sitting at .294 and a team ISO of .123, both of which are bottom five in the league. Tanaka has six or more strikeouts in three of his last four starts while allowing two or fewer earned runs in those same three games. Solid price and a great cash game option on the slate.

 

DraftKings DFS Infielders

Alex Avila – C, ARI vs LAA (DK - $3,300)

Love the savings on Avila today, especially for the fact he is up against a weak pitcher who struggles with lefties. That pitcher is Felix Pena, who is giving up a .364 wOBA and 1.23 HR/9 to lefties this season.

Justin Smoak – 1B, TOR vs BAL (DK - $4,000)

Smoak is facing off against Dylan Bundy tonight, who is giving up a .385 wOBA to lefties this season, along with 1.75 HR/9. Really like the power upside for Smoak with his massive .246 ISO vs right-handed pitchers this season. Price is good on him and up against a struggling pitcher.

DJ LeMahieu – 2B, COL vs SD (DK - $5,100)

Any time there is a game Coors Field you want some exposure to the players there and LeMahieu is a great option to do so. He comes in with a .376 wOBA and a .183 ISO vs left-handed pitchers this season and will have a strong platoon advantage vs Erlin. The Rockies clearly make a great stack tonight but are very expensive.

Tommy La Stella – 3B, CHC @ DET (DK - $2,700)

La Stella is a cheap option from the Cubs offense, who are in a great spot for a big night. The Cubs are up against Jordan Zimmerman, who is giving up a .349 wOBA and a 1.99 HR/9 to lefties this season. La Stella comes in with a .321 wOBA vs righties this season, along with a super low 11% strikeout rate.

Asdrubal Cabrera – SS, PHI @ WAS (DK - $3,800)

Cabrera is up against Tanner Roark, who is giving up a 39% fly ball rate and 1.11 HR/9 to lefties this season. This lines up nicely for Cabrera since he has a .358 wOBA and a .239 ISO vs right-handed pitchers this season. He also comes in with a 43% hard contact rate vs RHP, so certainly showing the power upside.

 

DraftKings DFS Outfielders

Jose Pirela – OF, SD @ COL (DK - $4,000)

Pirela gets a massive positive park shift going to Coors Field tonight, but makes more of a GPP option. He has a .319 wOBA and a .136 ISO vs left-handed pitchers this season, which aren't stellar numbers, but the park shift should help him tonight. Use him in a stack rather than a one-off.

Christian Yelich – OF, MIL vs CIN (DK - $5,200)

Love Yelich and the Brewers as a stack tonight, since they are up against Sal Romano, who is giving up a .387 wOBA, a 1.64 HR/9, a 35% hard contact rate and a 42% hard contact rate to lefties this season. Yelich has a .371 wOBA and a .200 ISO vs right-handed pitchers this season, which line up perfectly with how bad Romano is this season.

 

MLB DFS News and Injury Alerts

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REAL-TIME FANTASY NEWS

Brandon Sproat

Dealt to Brewers in Four-Player Trade
Jett Williams

Brewers Acquire Jett Williams From Mets
Freddy Peralta

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Jonas Valančiūnas

Jonas Valanciunas Questionable Versus the Wizards
Seth Jones

to Miss Olympics
Christian Braun

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Martin Pospisil

Makes Season Debut Wednesday
Jalen Suggs

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Teddy Blueger

Available Wednesday Night
Tom Wilson

Comes Off Injured Reserve
Luke Hughes

Devils Place Luke Hughes on Long-Term Injured Reserve
Valeri Nichushkin

Returns to Action Wednesday
Kris Letang

a Game-Time Call Wednesday
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Out of Action Again on Wednesday
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Collin Murray-Boyles

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Domantas Sabonis

Sidelined Wednesday
Kyle Tucker

Expected to Bat Second or Third in Dodgers' Lineup
Brandon Aiyuk

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Adam Scott

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Billy Horschel

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Josh Allen

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Jason Day

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Sam Burns

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Akshay Bhatia

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Christiaan Bezuidenhout

Looking to Build on Strong Fall in Season Debut
Kurt Kitayama

Hopes To Continue Strong Start to 2026 Season at American Express
CFB

Princewill Umanmielen Expected to Sign with LSU
Scottie Scheffler

Returns To American Express After Missing Last Year's Edition
Robert MacIntyre

Keeps Momentum Rolling Heading Into American Express
Brian Harman

Can Challenge at American Express if His Putter Stays Hot
Ben Griffin

Outstanding Form Continues Heading Into American Express
Matt Fitzpatrick

Continues Playing Well Following Outstanding Finish to 2025 Season
Patrick Cantlay

Looks to Get a Jump Start on His 2026 Season
Blades Brown

Set to Make First PGA Tour Appearance of 2026
Kevin Roy

Has Some Confidence Heading to Southern California
Josh Morrissey

Has Three-Point Night Against Blues
Min Woo Lee

Poised to Make Bigger Impact in 2026
Miro Heiskanen

Records Three Helpers Tuesday
Brandon Hagel

Stays Hot Tuesday Night
Ryan O'Reilly

Extends Scoring Streak With Three-Point Effort
Max Homa

Needs a Better Start for 2026
Konsta Helenius

Bags Three Points In Tuesday's Win
Tony Finau

Trying to Reverse Disturbing Trend
Anthony Cirelli

Injured Versus Sharks
Cam Davis

Aims for More Accuracy at American Express
Darcy Kuemper

Hurt on Tuesday Night
Isaiah Hartenstein

Unavailable Against Bucks
Myles Turner

Uncertain for Wednesday Night
Luisangel Acuña

Luisangel Acuna Sent to White Sox in Trade
Kevin Porter Jr.

Questionable Wednesday
Luis Robert Jr.

Mets Acquire Luis Robert Jr. from White Sox
Cam Thomas

Rejoins Nets Lineup for Meeting With Knicks
Jaylen Brown

Considered Probable Wednesday
Steven Adams

Out Indefinitely With Ankle Sprain
Deandre Ayton

Exits Early With Eye Injury
CFB

Justin Joly Bringing Strong Resume of Production to NFL
Los Angeles Chargers

Mike McDaniel Expected to Become Chargers Offensive Coordinator
Kel'el Ware

Unavailable on Tuesday
Mikko Rantanen

Out Tuesday
Andrew Peeke

Returns to Action Tuesday
Rodrigo Abols

Expected to Miss Several Months
Luke Hughes

Out Tuesday
Jonas Brodin

Will Miss Olympics
Carlos Beltran

Andruw Jones Elected to Baseball Hall of Fame
Alexandre Texier

Won't Play Tuesday
Kirby Dach

Rejoins Canadiens Lineup
Mark Williams

Active On Tuesday
Brice Sensabaugh

Unavailable Tuesday
De'Anthony Melton

In for Back End of Back-To-Back
CFB

Alberto Mendoza Expected to Land at Georgia Tech
Malik Nabers

Giants Hope Malik Nabers Will be Back for Start of Training Camp
CFB

Duke Suing Quarterback Darian Mensah
Cam Skattebo

Should be Ready by OTAs
George Kittle

Expects to Return "Well Before November"
CFB

Alberto Mendoza Entering Transfer Portal
Mookie Betts

Plans to Retire at the End of his Current Contract
Tennessee Titans

Titans Set to Hire Robert Saleh as Next Head Coach
Miami Dolphins

Dolphins Expected to Hire Jeff Hafley as Next Head Coach
Zach Charbonnet

has Torn ACL
Zach Charbonnet

Needs Knee Surgery, Out for Rest of Playoffs
Tennessee Titans

Mike McCarthy a Finalist for Titans Head-Coaching Job?
Colston Loveland

Suffers Concussion in Divisional Round Loss
Kyren Williams

Scores Two Touchdowns in Divisional Round Win
Buffalo Bills

Bills Fire Head Coach Sean McDermott
Rhamondre Stevenson

Returns in Sunday's AFC Divisional Round Game
Ha-Seong Kim

has Finger Surgery, Out 4-5 Months
Rhamondre Stevenson

Questionable to Return on Sunday With Eye Injury
Woody Marks

Returns Following Brief Exit on Sunday
Dalton Schultz

Won't Return in Sunday's AFC Divisional Round Game
Aaron Rodgers

Steelers Open to Aaron Rodgers Returning in 2026?
Jarrett Stidham

to Start AFC Championship Game
Zach Charbonnet

Questionable to Return Against 49ers
CFB

Darian Mensah Entering Transfer Portal
J.T. Realmuto

Signs Three-Year Deal to Return to Phillies
Bo Bichette

Agrees to Three-Year Contract With Mets
CFB

Weber State Signs former Ohio State, Cal Quarterback Devin Brown
Bo Bichette

Phillies the "Overwhelming" Favorite to Sign Bo Bichette

RANKINGS

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RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP