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Week 16 Starts & Sits - All Starting Pitcher Matchups

Nick Mariano's recommended fantasy baseball starts and sits for all Week 16 starting pitcher matchups. Unearth potential streamers, two-start SPs and sleepers.

With the All-Star week in our rearview mirror, we as fantasy owners are now on a nonstop train towards late September's championship weeks. We here at RotoBaller offer our analysis and dynamic pitching scores for each matchup to frame your start/sit decisions and get you on top of that podium. In case you missed it, this is our sixth year now writing this weekly column, helping fantasy baseball managers pick the best pitchers weekly.

Below are the projected starting pitching matchups for Week 16 -- July 15th through July 21st -- which will be updated as rotations are announced and tweaked. This column will be continuously updated and adjusted for any postponements or rotation shuffles, reflecting official beat writer speculation for as many unconfirmed rotation slots as possible.

For every week of the fantasy baseball season, we look to analyze all of the projected starting pitcher matchups and put together our optimal lineups. Here at RotoBaller, we believe that it’s key to analyze every SP matchup, each and every week, to help determine which SPs to start/sit and identify some sneaky streams. Let's win some leagues!

Be sure to check all of our fantasy baseball lineup tools and resources:

 

SP Matchups & Start/Sit Recommendations

This weekly piece considers the pitcher’s opponents, their outlook against lefties and righties, some ballpark factors and historical splits. With all of this information, we then provide our start/sit recommendations for each starting pitcher matchup for the approaching week of fantasy baseball.

Score values typically range from about 40-60, with higher values being superior. A 50 is the theoretical "Start/Sit" cutoff, but you should use the color-coded scores for valuable context to make your own decisions. Streamers and those relying on counting stats more than all-around ratios can target 48s and 49s, for example. Those set for two-start weeks are highlighted in yellow. Openers will have an asterisk if no "true" starter is announced by team beat writers.

This column will be updated daily as more rotations and starters are announced through July 21st.

More Fantasy Baseball Analysis




POPULAR FANTASY TOOLS

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Import Your Leagues
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All Pitcher Matchups
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24x7 News and Alerts

REAL-TIME FANTASY NEWS

CFB

Five-Star Quarterback Jared Curtis Flips Commitment From Georgia to Vanderbilt
CFB

Florida Hiring Brad White as Defensive Coordinator
Kyle Schwarber

Giants Have Checked in on Kyle Schwarber
Willson Contreras

Willing to Waive his Full No-Trade Clause?
Brandon Aiyuk

49ers "Hopeful" Brandon Aiyuk Will Play in 2025
Zach Edey

CBB DFS: DraftKings Daily Fantasy College Basketball Picks - Today's Top Lineups (12/2/25)
Brayden Point

Without Timetable for Return
Jake Walman

Still Out Tuesday
Mason Appleton

Misses Tuesday's Contest
Oliver Ekman-Larsson

Good to Go Tuesday
Conor Garland

Out on Tuesday
Petr Mrazek

Considered Day-to-Day
Tyson Foerster

Hurt in Monday's Loss
Trey Murphy III

May Skip Another Game Tuesday
Zion Williamson

Back in Pelicans Lineup Tuesday
Draymond Green

Probable for Tuesday Night
Jimmy Butler III

Questionable to Play Tuesday
Jakob Poeltl

Daily NBA Prop Bets - Top Player Props, Value Picks and Quick Odds (12/2/25)
Derrick White

Likely Available Tuesday
Paul George

Listed as Questionable for Tuesday
Joel Embiid

Won't Play Against Wizards
NHL

NHL DFS Picks and Heat Map (Premium Content) - December 2, 2025
Viktor Arvidsson

NHL DFS Lineup Picks for DraftKings: Goalies, Value Plays, Stacks, and Power Plays Picks (12/2/25)
Tyrone Tracy Jr.

Carted Off With Hip Injury on Monday Night
Edwin Díaz

Mets Still Interested in Re-Signing Edwin Diaz
Devin Williams

Agrees to Three-Year Deal With Mets
Cole Ragans

Red Sox Targeting Cole Ragans in a Trade?
CFB

Kentucky Hires Oregon Offensive Coordinator Will Stein As Head Coach
Davante Adams

Not Dealing With a Serious Injury
Brandon Miller

Unavailable on Monday
Kyler Murray

Surgery Not on the Table for Kyler Murray
Duncan Robinson

Absent Against Atlanta
Marvin Harrison Jr.

in Danger of Missing Week 14?
Jalen Duren

Back in the Lineup on Monday Evening
Noah Clowney

Cleared to Play Versus Charlotte
Giannis Antetokounmpo

Active On Monday
Danila Yurov

Won't Play on Tuesday
Michael Porter Jr.

Back in Action on Monday
Sam Merrill

Unavailable Versus Pacers
David Pastrnak

to Remain Out Tuesday
Alexandre Sarr

Won't Play Versus Milwaukee
Adam Gaudette

Iffy for Monday
CFB

Kalani Sitake the Top Target for Penn State Coaching Job
Logan Cooley

a Game-Time Decision Monday
Josh Norris

Available Monday
Neal Pionk

Remains Out Monday
Lonzo Ball

Ruled Out on Monday
Jimmy Snuggerud

to Miss Six Weeks After Wrist Surgery
Justin Herbert

Having Hand Surgery on Monday
Steven Adams

Out Against Jazz
Kyler Murray

Cardinals Won't Open Kyler Murray's Practice Window This Week
Darius Garland

Unavailable Monday
Sauce Gardner

Not a Candidate to Go on Injured Reserve
Kristaps Porzingis

Out of Action Versus Pistons
Jayden Daniels

Not Cleared for Contact, Decision on Week 14 Status Delayed
CFB

Josh Heupel Says He's Not a Candidate for Penn State Head Coach Job
Trey Hendrickson

Doubtful to Return in Week 14
Tee Higgins

Still in the Concussion Protocol
Drake London

"has a Chance" to Play in Week 14
J.J. McCarthy

in Line to Start in Week 14?
Aaron Jones Sr.

Not Dealing With Serious Shoulder Injury, Likely Day-to-Day
Sam Darnold

Dealing With Ankle Injury, "Should be Good" for Week 14
CFB

Will Stein, Brian Hartline the Top Candidates for Kentucky Job?
CFB

Nebraska Fires Defensive Coordinator John Butler After One Season
CFB

UCLA Expected to Hire Bob Chesney as Next Head Coach
Sauce Gardner

Officially Week-to-Week with Strained Calf
CFB

Lane Kiffin to Make $13 Million Salary, Ties Kirby Smart
CFB

Buster Faulkner, Joey Halzle Candidates for Florida Offensive Coordinator Job?
CFB

Kentucky Officially Fires Mark Stoops
Justin Herbert

Has Metacarpal Fracture in Left Hand
Amon-Ra St. Brown

Week 14 Availability Up in the Air
VEG

Carter Hart Expected to Make Golden Knights Debut Tuesday
Pyotr Kochetkov

Remains Without Timeline For Return
Boone Jenner

Close to Returning
Lian Bichsel

Exits With Injury Sunday
Petr Mrazek

Injured in Sunday's Loss
Zach Ertz

Leads Washington in Receiving in Overtime Loss
James Cook

Handles Career-High 32 Carries for 144 Yards in Win
Justin Herbert

Planning to Play Through Broken Bone in Left Hand in Week 14
CFB

Lane Kiffin to be Introduced as LSU's Next Head Coach on Monday
CFB

Florida Poised to Land Jon Sumrall as Next Head Coach
CFB

Alex Golesh Taking Over Auburn Head-Coaching Job
CFB

Arkansas Expected to Hire Ryan Silverfield as Next Head Coach
Zack Wheeler

Likely to Return in May
Ryan Helsley

Agrees to Two-Year Deal With Orioles
Dylan Cease

Agrees With Blue Jays on Seven-Year, $210 Million Deal
Anthony Rendon

Angels Could Buy Out Final Year of Anthony Rendon's Contract
Josh Hader

Says his Shoulder is "Back to Normal"
Ketel Marte

Diamondbacks "Actively Listening" on Ketel Marte

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