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San Francisco 49ers running back Isaac Guerendo (shoulder) is expected to miss a couple of weeks, according to Matt Maiocco of NBC Sports. Guerendo will miss time after getting injured during Saturday's training camp practice. While the 25-year-old still has time to get ready for the start of the regular season, he will miss important reps during practice and the preseason as he gets ready to serve as Christian McCaffrey's primary backup in 2025. With Guerendo now out for a few weeks, it will give rookie Jordan James more opportunities to run with the first-team offense when CMC needs a breather. In addition to James, Patrick Taylor Jr. and Ameer Abdullah should see more work in practices. When healthy, Guerendo's raw athletic abilities make him an intriguing handcuff if you take the leap on McCaffrey.--Keith Hernandez
Source: NBC Sports Bay Area - Matt Maiocco
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