X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Daily Stats & Leaders
All Pitcher Matchups
Compare Any Players
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

Free MLB Betting Picks - Today's Best Bets, Expert Predictions, Odds (9/28/22)

justin verlander fantasy baseball rankings pitchers draft sleepers MLB injury news

John Brubaker's top MLB betting picks and best bets for today's MLB games on 9/28/22. His free picks against the spread, teasers, parlays, and MLB player props.

Happy Wednesday, RotoBallers, we're back for another day of MLB betting picks! Make sure you're following my Twitter, as I can't guarantee that I'll always be able to get the added plays written here in the article, but I will typically add whatever else I'm playing throughout the day. The entire RotoBaller team has been working around the clock to make sure we can get you guys the best betting picks, props, and lineups throughout the season. We're happy you're here with us and are looking forward to an extremely profitable 2022 season!

Attention fellow sports bettors! We have some exciting news to share as we are now officially partnered with various sportsbooks and have some sweet sports betting promo offers! Get your deposit bonus, as well as a year of free RotoBaller Premium access, when you sign up with a new account today! After you're signed up, use our picks in this article for spreads, totals, and props to win big.

If you're new, or just a refresher to those who read my articles last season, I'm John Brubaker. I've been betting MLB baseball games for four years now, and this is my second MLB season working with the great folks at RotoBaller. I've created my own betting model to help me create and identify value on run lines, totals, and money lines. In this article, I'll be providing my favorite betting picks for the MLB games on Wednesday, September 28, 2022.

Featured Promo: New Novig users get a $25 purchase match (50% discount up to $25) on your first Novig deposit, and 3 free months of RotoBaller's "Big-4" Premium Pass (NFL, NBA, MLB, NHL) which includes exclusive tools for Betting, Props, DFS and more! CLAIM IT NOW

 

LucidMedia's 2022 MLB Betting Picks

  • Season to Date: 74-77-2, -19.95 units
  • Sides: 35-37-1, -13.96 units
  • Totals: 38-40-1, -7.69 units
  • Props: 1-0 +1.70 units

 

Today's MLB Betting Picks - Cardinals @ Brewers

O/U: 7.5 | Moneyline: MIL -142

STL: Jose Quintana | MIL: Brandon Woodruff

I don't even want to get into yesterday's frustrating day, but we'll look to bounce back today. I'll be running back the first inning under in this Cardinals/Brewers series. The Cardinals clinched the NL Central with their victory last night, so I can't expect to see their top studs in the lineup this evening.

The visiting Cardinals will send Jose Quintana (6-6, 3.03 ERA). Quintana is having an awesome 2022, split between his time in Pittsburgh and St. Louis. He's also been great in the first inning, allowing a run in just two of 14 starts on the road as well as just five of 32 starts overall. Quintana will be making his third start against the Brew Crew this season, allowing a run in one of the two. That was all the way back on April 28th, when Quintana was with Pittsburgh.

The Brewers will be sending Brandon Woodruff (12-4, 3.18 ERA) to the mound. While it seemed like every time I either bet on Woodruff or played him in DFS he did poorly, he's actually having another excellent season for Milwaukee. He's been great in the first inning as well, allowing a run in just one of 11 starts at home, and just four of 25 starts overall. He's a perfect 2-0 to the first inning under against St. Louis this season, and I have to imagine he won't be facing their top lineup this afternoon.

FanDuel Sportsbook has the first inning under at just -136, which is great value in my estimation. Albeit we lost this play last night, every day is a different matchup. My model gives the first inning under a 63.11% chance of hitting, good for "true" odds of -171.

Pick: Under 0.5 First-Inning Runs (-136) FanDuel Sportsbook, 1 unit

 

Sports Betting Promo Offers

Featured Promo: Get any Betting Premium Pass for 50% off using code THANKS. Win more with exclusive betting picks from proven winners across 9 sports! Find optimal bets with our Betting Picks Tool and Bet Weighting Tool and follow along in our VIP chat rooms! Go Premium, Win More!

 

Today's MLB Betting Picks - Diamondbacks @ Astros

O/U: 6.5 | Moneyline: HOU -200

ARI: Zac Gallen | HOU: Justin Verlander

We'll head to Houston for our second first inning under tonight. The Astros have been very good offensively in the opening frame all season, but shouldn't be so lucky tonight against one of the best pitchers in the league this season, Zac Gallen.  

Gallen (12-3, 2.46 ERA) has had an absolutely remarkable season in 2022. Many said it was just a matter of him staying healthy to put together a season like this season, and they were correct. He's been great in the first inning this year as well, allowing a run in just two of 14 starts on the road, and just four of 30 starts overall. It'll be one of his more difficult matchups this season, but he's faced daunting lineups like the Dodgers and Padres all season, as well as making multiple starts at Coors Field.

On the other hand, the Astros will be sending heavy AL Cy Young favorite Justin Verlander (17-4, 1.82 ERA) to the mound. I've said it before but it is absolutely incredible what JV has done this year, putting up career bests in WHIP, ERA, and ERA+ at age 39 and coming off of Tommy John surgery. He's obviously been fantastic in the first inning also, coming into this one a perfect at home, holding opponents off the board in each of his 13 starts, as well as in 25 of 26 starts overall.

FanDuel Sportsbook has the first inning under at a relatively juiced price of -160. While I do feel like that number is high on a relatively volatile bet, we're still getting pretty good value here. My model gives the first inning under a 63.86% chance of hitting, good for "true" odds of -177. I'll also be taking a look at the F5 under 3.5 runs in this one.

Pick: Under 0.5 First-Inning Runs (-160) FanDuel Sportsbook, 1 unit

Good luck, RotoBallers, and make sure to follow my Twitter for more plays. Talk to you tomorrow!



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy baseball app for iPhone and Android with 24x7 player news, injury alerts, sleepers, prospects & more. All free!



More Fantasy Baseball Analysis




POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Daily Stats & Leaders
All Pitcher Matchups
Compare Any Players
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

REAL-TIME FANTASY NEWS

New York Jets

Jets Not Expected to Fire Aaron Glenn
Kyle Pitts Sr.

Suiting Up Against Saints in Week 18
Drake London

Will Play Against Saints on Sunday
Josh Jacobs

Packers Resting Josh Jacobs in Week 18
CFB

Transfer QB Billy Edwards Commits to North Carolina
CFB

Sam Leavitt Visiting Texas Tech on Saturday
Jaylin Noel

Jayden Higgins and Jaylin Noel Projected for Larger Roles in Week 18
Green Bay Packers

Packers Resting Key Players in Week 18
Nico Collins

Won't Play Against Colts in Week 18
Jamal Murray

Expected to Play Against Nets
Giannis Antetokounmpo

Listed as Probable for Sunday
Tobias Harris

Out at Least Two Weeks with Hip Sprain
Jalen Duren

to Miss at Least One Week with Ankle Injury
Vince Williams Jr.

Misses Eighth Straight Game
Maxime Raynaud

Cleared to Play Sunday After Knee Scare
Isaiah Hartenstein

Remains Out Versus Suns
Nathan MacKinnon

Takes Over Scoring Lead With Four-Point Effort
Herbert Jones

Misses Seventh Straight Game
Nikita Kucherov

Bags Five Points Against Sharks
Saddiq Bey

Ruled Out Versus Heat
Darren Raddysh

Celebrates Hat Trick in Big Win
Jordan Binnington

Logs First Shutout of Season
Nicolas Claxton

Sidelined Versus Nuggets
Bennedict Mathurin

Ruled Out Sunday with Thumb Sprain
Auston Matthews

Becomes Maple Leafs' All-Time Goals Leader
Kyshawn George

Misses Fifth Straight Game
Jake McCabe

Exits Loss Early
Philip Rivers

Expected to Interview for NFL Head-Coaching Jobs
Tom Wilson

Escapes Serious Injury
Brock Purdy

Suffers a Stinger in Week 18 Loss
Jaylen Waddle

Not Expected to Suit Up in Week 18
De'Von Achane

Not Expected to Play Against Patriots in Week 18
Lauri Markkanen

Back on Saturday Night
Keyonte George

Available Versus Golden State
PJ Hall

Starting Again on Saturday Night
Joel Embiid

Upgraded to Available on Saturday
Karl-Anthony Towns

Returning on Saturday Night
George Kittle

Officially Active for Week 18
Ricky Pearsall

Inactive for Saturday's Game
Joel Kiviranta

Misses Road Trip
Gavin Brindley

Out Saturday
Casey DeSmith

Granted Leave of Absence
Tanner Jeannot

Remains Absent Saturday
Trevor Moore

Won't Play Saturday Night
Shayne Gostisbehere

Set to Return Saturday
William Nylander

Misses Fourth Straight Game
Wan'Dale Robinson

Giants Place Wan'Dale Robinson on Injured Reserve
Breece Hall

Ruled Out, Ending His Season
CFB

DJ Lagway Expected To Visit Florida State
Kyle Tucker

Blue Jays "Remain the Favorite" to Sign Kyle Tucker
Jalen Suggs

to Undergo Further Testing on Knee Injury
Devin Vassell

to Miss "More Than a Few Games"
Davante Adams

Unlikely to Play in Regular-Season Finale
Jusuf Nurkić

Jusuf Nurkic Dealing with Toe Injury Ahead of Saturday
Lauri Markkanen

Could Miss Second Straight Game
Jake DeBrusk

Records Season-High Three Points Friday
NHL

NHL DFS Picks and Heat Map (Premium Content) - January 3, 2026
Danila Yurov

Scores Twice in Friday's Win
Alexis Lafrenière

Alexis Lafreniere Sets Up Three Goals in Winter Classic Win
Mika Zibanejad

Produces Historic Winter Classic Performance
Mackenzie Blackwood

Placed on Injured Reserve
Seth Jones

Sustains Upper-Body Injury in Winter Classic Loss
T.J. Watt

Cleared to Play in Week 18
Isiah Pacheco

Could be Rested Against Raiders
Amon-Ra St. Brown

Officially Questionable for Week 18
De'Von Achane

Doubtful to Face the Patriots
Aaron Jones Sr.

Won't Play in Week 18
CFB

Joey Aguilar Undergoes Surgery to Remove Tumor on Friday
CFB

Texas the "Team to Beat" for Transfer Running Back Isaac Brown
CFB

Rocco Becht to Follow Matt Campbell to Penn State?
CFB

Texas Targeting Cam Coleman in Transfer Portal
CFB

Former Texas Running Back CJ Baxter Visiting Kentucky
CFB

Beau Pribula Visiting Virginia Tech, Georgia Tech
Bo Bichette

Yankees Showing Interest in Bo Bichette
Houston Astros

Astros Sign Tatsuya Imai to Three-Year Deal
CFB

Lane Kiffin Interested in Sam Leavitt, Brendan Sorsby at LSU
CFB

Deuce Knight Officially Entering Transfer Portal
CFB

Kewan Lacy Expected to Be Full-Go Against Georgia
CFB

Chip Kelly Named Northwestern Offensive Coordinator
CFB

Penn State Working to Hire D'Anton Lynn as Next Defensive Coordinator
CFB

Omar Cooper Expected to be Full-Go for Rose Bowl
CFB

Marcus Freeman Staying with Notre Dame for 2026 Season
CFB

Star Wideout Cam Coleman Entering Transfer Portal

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP