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DraftKings Daily Fantasy Baseball Picks (4/22/19): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on April 22nd, 2019. Daniel E. Dobish's MLB DFS analysis and sleepers for building optimal DFS rosters.

For Monday's slate of Major League Baseball games, I'll focus on the contests (first pitch of 7:05 PM EST and later). Be sure to double-check the weather and the lineups before finalizing your roster.

There will be some possible light rain affecting the start of the Philadelphia Phillies-New York Mets battle, although the game should get started with minimal interruption. At Fenway Park, the Detroit Tigers-Boston Red Sox game has a 70 percent or greater chance of rain all day, so it's likely we'll have a postponement in that game. If they do get underway they will face a stiff 11-14 mph wind blowing in directly from center field to home plate. It's best to avoid all Tigers and Red Sox just to be on the same side. Wind will be a factor at Busch Stadium for the Milwaukee Brewers-St. Louis Cardinals battle, blowing 12-15 mph out to left field.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 4/22/19. The lineup picks will range from some of the elite players to mid-priced options and value plays. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. Be sure to also check out all the Vegas Odds for today's slate. If you have any questions or comments, contact me on Twitter @danieledobish.

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DraftKings DFS Starting Pitchers

Yonny Chirinos - P, TB vs. KC ($7,400)

Chirinos has piled up 17.5 Fantasy Points Per Game (FPPG), yet he flies under the radar with a low salary. Take advantage. While he was torched in a start April 12 in Toronto, allowing six earned runs in just 2 1/3 innings, he has won his other three appearances while allowing a total of just one earned run and five hits in 17 innings. Overall he has posted a 0.83 WHIP, and he has just four walks to 19 strikeouts over 19 1/3 innings.

Brad Peacock - P HOU vs. MIN ($8,200)

The Astros enter play with a 7-3 mark across their past 10 games against right-handed starting pitching, and they're 6-1 in Peacocks' past seven starts overall, and 6-1 in his past seven home outings, too. Conversely, the Twins are just 1-8 in their past nine road outings, and 1-10 in his past 11 road starts against teams with a winning overall mark. That bodes well for Peacock's outlook on Monday night, and his 0.81 WHIP across two starts and four outings doesn't hurt, either.

 

DraftKings DFS Infielders

Yasmani Grandal - C, MIL at STL ($4,100)

Grandal has been raking, checking in fifth among all catchers with a .338 average (22-for-65) with two doubles, five homers and 10 RBI. He also ranks second among all backstops in runs scored (14), behind only Seattle's Omar Narvaez, and Grandal is one of just two catchers with an OPS over 1.013 or higher.

Trey Mancini - 1B, BAL vs. CWS ($4,900)

Mancini will get a crack at LHP Manny Banuelos, and that should bode well for him and his owners. He is slashing a robust .379/.455/.759 with five doubles and two homers in 29 at-bats against left-handed starting pitchers.

Kolten Wong - 2B, STL vs. MIL ($4,400)

You'll want plenty of Cards and Brewers with a Jetstream blowing out to left field. Wong has managed a solid .320/.444/.600 slash line vs. right-handed pitching, collected seven extra-base hits with 10 RBI, 10 walks and 10 strikeouts while also adding 10 runs scored.

Yoan Moncada - 3B, CWS at BAL ($4,900)

Moncada has been one of the most consistent hitters from the hot corner, posting a .322 average with three doubles, six homers and 13 RBI vs. RHP, also posting 13 runs scored. While he has managed 18 strikeouts in just 59 at-bats, the power numbers make him worth using most nights. That's especially true against O's RHP David Hess, who enters with a subpar 5.57 ERA across 21 innings.

 Gleyber Torres - SS, NYY at LAA ($3,900)

Torres has rolled up some decent numbers vs. RHP. While his .269 average is just so-so, he has four doubles, four homers and eight RBI in 67 at-bats against righties, and he could be in for a productive night against Angels RHP Matt Harvey, who has an ugly 0-2 record, 9.64 ERA and 1.82 WHIP, while opponents are hitting a collective .333 against him through 18 2/3 innings across four outings.

 

DraftKings DFS Outfielders

Joey Gallo - OF, TEX at OAK ($5,000)

Gallo doesn't have a great average, but that's not why you grab him in DFS. You grab him for his tremendous power, and it could be on full display against RHP Chris Bassitt, who makes his first start of the season. Gallo has 10 extra-base hits, including six homers, vs. RHP, and he has a .755 slugging percentage and 1.162 OPS.

Tommy Pham - OF, TB vs. KC ($4,300)

Pham enters play with four homers, 10 RBI, nine walks and a solid .297/.387/.484 slash line against right-handed pitching.

MLB DFS News and Injury Alerts




REAL-TIME FANTASY NEWS

Jackson Holliday

Orioles Reinstate Jackson Holliday From Injured List on Monday
Ronald Acuña Jr.

Braves Reinstate Ronald Acuna Jr. From Injured List on Monday
Jose Altuve

Astros Put Jose Altuve on Injured List With Oblique Strain
Larry Nance Jr.

is Questionable for Game 1 on Tuesday
OG Anunoby

is Probable for Tuesday's Game 1
Luke Kornet

is Cleared for Game 1
New Orleans Pelicans

Jamahl Mosley Agrees to Become Pelicans Next Head Coach
De'Aaron Fox

is Ruled Out for Game 1 on Monday
Ukko-Pekka Luukkonen

Set to Start Game 7
Corey Seager

Going on Injured List With Back Injury
Tage Thompson

Can Match Franchise Record With Another Multi-Point Game
Nick Suzuki

Seeks More Road Success Monday
Lane Hutson

Riding a Five-Game Assist Streak Into Game 7
Filip Gustavsson

Needs Offseason Surgery
Jeremy Peña

Jeremy Pena Reinstated and Starting on Monday Against Twins
Cam Skattebo

Dynasty Stock Rising Following NFL Draft
Kaleb Johnson

Logging First-Team Reps in OTAs
Evan Engram

Dynasty Value Fading After Production Decline in 2025
TreVeyon Henderson

Dynasty Outlook Clouded By Split Backfield in New England
Caleb Williams

' Dynasty Upside Remains Sky-High Entering 2026
Bijan Robinson

Is Bijan Robinson the No. 1 Overall Player in Dynasty Formats?
Woody Marks

Should Have Plenty of Opportunities to Catch Passes
Drew Allar

Working as QB4 in First OTA Session
Aaron Rodgers

Reports to Steelers Facilities on Monday
Alvin Kamara

Saints Remain Non-Committal on Alvin Kamara's Future
Chris Olave

Saints Continue to Work on Extension With Chris Olave
Parker Washington

a Sneaky Trade Target in Dynasty Leagues?
Melquizael Costa

Drops Decision At UFC Vegas 117
Jarquez Hunter

Can Jarquez Hunter's Dynasty Outlook Improve in Year 2?
Arnold Allen

Bounces Back
James Conner

Off the Dynasty Radar Entirely?
Elijah Arroyo

Will Elijah Arroyo Continue to Have Trouble Getting on the Field?
Daniel Santos

Suffers Second-Round TKO Loss
Tre Tucker

Not a Long-Term Solution in Dynasty Leagues
MMA

Dohoo Choi Wins His Third Consecutive Fight
Malcolm Wellmaker

Suffers His Second Loss In A Row
Juan Diaz

Scores Second-Round Submission
Christian Edwards

Defeated At UFC Vegas 117
CFB

Transfer Running Back Arnold Barnes Visiting Iowa State on Monday
Modestas Bukauskas

Gets Split-Decision Win
Jack Bech

a Dynasty Hold as New-Look Raiders Offense Takes Shape
Jaydon Blue

a Low-Value Dynasty Stash Until Depth Charts are Settled
Makai Lemon

a Top-Five Pick in Dynasty Rookie Drafts
George Kittle

a Dynasty Buy with League-Winning Potential
Jhostynxon Garcia

Expected to Join the Pirates on Tuesday
Chris Rodriguez Jr.

a Dynasty Sleeper with High Touchdown Potential
Tobias Harris

Goes Cold in Game 7 Loss
Quinn Hughes

Open to Signing Extension This Offseason
Jalen Duren

Finishes Game 7 with Quiet Line
Cade Cunningham

Endures Cold Shooting Night Sunday
Joel Eriksson Ek

Misses Second Round Due to Heel Injury
Sam Merrill

Catches Fire in Game 7 Win
Evan Mobley

Posts Versatile Double-Double in Game 7
Jonas Brodin

Sits Out Round 2 Due to Toe Injury
Donovan Mitchell

Guides Cavaliers Into East Finals
Sam Malinski

Practices Fully Sunday
Jarrett Allen

Scores 23 Points in Cavs' Game 7 Rout of Pistons
Josh Manson

Rejoins Practice
Kevin Huerter

Active on Sunday Night
Caris LeVert

Duncan Robinson, Caris LeVert Available Sunday
Dean Wade

Max Strus Replaces Dean Wade in Starting Lineup Sunday
Luke Kornet

Iffy for Monday
Larry Nance Jr.

Won't Play Sunday
De'Aaron Fox

Listed as Questionable for Monday's Action
Jalen Williams

Officially Available for Game 1 Against Spurs
Shai Gilgeous-Alexander

Named MVP for Second Straight Year
Colt Emerson

Mariners Promoting Top Prospect Colt Emerson to Major Leagues
Bones Hyland

Wants to Stay in Minnesota
Munetaka Murakami

Fantastic First Season Continues With Two More Homers
Cristopher Sánchez

Cristopher Sanchez Dazzles With 13-Strikeout Complete Game on Saturday
Blake Snell

to Undergo Elbow Surgery on Tuesday
Clay Holmes

Could Miss Around Three Months
Jose Altuve

Exits After Swing
Corey Seager

Absent With Back Spasms on Saturday
Jeremy Lauzon

Misses Saturday's Practice
Mark Stone

Doesn't Practice Saturday
Josh Manson

Misses Practice, Considered Day-to-Day
Brent Burns

Day-to-Day Ahead of Conference Finals
Cale Makar

Considered Day-to-Day
Alex Lyon

Likely to Start Game 6 Against Canadiens
Owen Power

Available Saturday
Trevor Story

Hits the Injured List With Groin Injury
Blake Snell

Likely to Need Elbow Surgery
Kyle Schwarber

on a Heater, Hits Two More Homers to Take Major-League Lead
Clay Holmes

Suffers Fractured Fibula on Friday Night
Blake Snell

Heads to 15-Day Injured List
Blake Snell

Scratched From Start on Friday for Undisclosed Reasons
Max Fried

Heading to Injured List With Elbow Bone Bruise
CFB

Julian Sayin Looking To Build Off Of Strong Debut Season
CFB

College GameDay Set for First Three Weeks
CFB

Jeremiah Smith Aiming For Ohio State Receiving Records
CFB

Keshaun Singleton Projects as Auburn's WR1
CFB

Jeremiah Cobb Impresses New Auburn Staff
CFB

Alberto Mendoza Very Likely to Start for Georgia Tech
CFB

Charles Woodson Jr. Commits to Michigan
Jordan Westburg

to Have Season-Ending Elbow Surgery
Melquizael Costa

Set For UFC Vegas 117 Main Event
Arnold Allen

A Favorite At UFC Vegas 117
Daniel Santos

Set For UFC Vegas 117 Co-Main Event
MMA

Dohoo Choi Returns At UFC Vegas 117
Juan Diaz

Set To Make His UFC Debut
Malcolm Wellmaker

Looks To Bounce Back
Christian Edwards

Set For His UFC Debut
Modestas Bukauskas

Looks To Get Back In The Win Column
Lane Hutson

Contributes Two Assists in Game 5 Victory
Nick Suzuki

Amasses Three Points in Crucial Victory Thursday
Juraj Slafkovsky

Dishes Out Three Assists in Game 5 Win
Carter Hart

Stops 31 Pucks in Series-Clinching Win
CFB

Virginia Tech Lands Commitment from Four-Star QB Peter Bourque
CFB

NFL Veteran Tom Moore Joins Iowa Coaching Staff
CFB

Can Cam Cook Dominate in Return to Big 12?
CFB

ACC, Big 12 Support 24-Team College Football Playoff
CFB

Anthony Colandrea Looking to Elevate Nebraska Back to National Contention
CFB

Kwazi Gilmer Set for Big Impact at Nebraska
Justin Thomas

Trending Well Ahead of PGA Championship Despite Concerning Form
J.J. Spaun

Trending Up Ahead of PGA Championship
Adam Scott

Riding Strong Form Into PGA Championship
Patrick Reed

Looking to Make Another Run at PGA Championship
PGA

Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

Looks to Complete Career Grand Slam at Aronimink
Brandt Snedeker

Not the Best Option for the PGA Championship
Rasmus Hojgaard

a Volatile Option at PGA Championship
Maverick McNealy

Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
Hideki Matsuyama

Attempts to Improve Over 2025 PGA Championship
Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Ben Griffin

Attempting to Bounce Back After Truist Championship
CFB

Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Harris English

Will Need His Putter to Thrive at Aronimink
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF