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DraftKings Daily Fantasy Baseball Picks (4/22/19): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on April 22nd, 2019. Daniel E. Dobish's MLB DFS analysis and sleepers for building optimal DFS rosters.

For Monday's slate of Major League Baseball games, I'll focus on the contests (first pitch of 7:05 PM EST and later). Be sure to double-check the weather and the lineups before finalizing your roster.

There will be some possible light rain affecting the start of the Philadelphia Phillies-New York Mets battle, although the game should get started with minimal interruption. At Fenway Park, the Detroit Tigers-Boston Red Sox game has a 70 percent or greater chance of rain all day, so it's likely we'll have a postponement in that game. If they do get underway they will face a stiff 11-14 mph wind blowing in directly from center field to home plate. It's best to avoid all Tigers and Red Sox just to be on the same side. Wind will be a factor at Busch Stadium for the Milwaukee Brewers-St. Louis Cardinals battle, blowing 12-15 mph out to left field.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 4/22/19. The lineup picks will range from some of the elite players to mid-priced options and value plays. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. Be sure to also check out all the Vegas Odds for today's slate. If you have any questions or comments, contact me on Twitter @danieledobish.

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DraftKings DFS Starting Pitchers

Yonny Chirinos - P, TB vs. KC ($7,400)

Chirinos has piled up 17.5 Fantasy Points Per Game (FPPG), yet he flies under the radar with a low salary. Take advantage. While he was torched in a start April 12 in Toronto, allowing six earned runs in just 2 1/3 innings, he has won his other three appearances while allowing a total of just one earned run and five hits in 17 innings. Overall he has posted a 0.83 WHIP, and he has just four walks to 19 strikeouts over 19 1/3 innings.

Brad Peacock - P HOU vs. MIN ($8,200)

The Astros enter play with a 7-3 mark across their past 10 games against right-handed starting pitching, and they're 6-1 in Peacocks' past seven starts overall, and 6-1 in his past seven home outings, too. Conversely, the Twins are just 1-8 in their past nine road outings, and 1-10 in his past 11 road starts against teams with a winning overall mark. That bodes well for Peacock's outlook on Monday night, and his 0.81 WHIP across two starts and four outings doesn't hurt, either.

 

DraftKings DFS Infielders

Yasmani Grandal - C, MIL at STL ($4,100)

Grandal has been raking, checking in fifth among all catchers with a .338 average (22-for-65) with two doubles, five homers and 10 RBI. He also ranks second among all backstops in runs scored (14), behind only Seattle's Omar Narvaez, and Grandal is one of just two catchers with an OPS over 1.013 or higher.

Trey Mancini - 1B, BAL vs. CWS ($4,900)

Mancini will get a crack at LHP Manny Banuelos, and that should bode well for him and his owners. He is slashing a robust .379/.455/.759 with five doubles and two homers in 29 at-bats against left-handed starting pitchers.

Kolten Wong - 2B, STL vs. MIL ($4,400)

You'll want plenty of Cards and Brewers with a Jetstream blowing out to left field. Wong has managed a solid .320/.444/.600 slash line vs. right-handed pitching, collected seven extra-base hits with 10 RBI, 10 walks and 10 strikeouts while also adding 10 runs scored.

Yoan Moncada - 3B, CWS at BAL ($4,900)

Moncada has been one of the most consistent hitters from the hot corner, posting a .322 average with three doubles, six homers and 13 RBI vs. RHP, also posting 13 runs scored. While he has managed 18 strikeouts in just 59 at-bats, the power numbers make him worth using most nights. That's especially true against O's RHP David Hess, who enters with a subpar 5.57 ERA across 21 innings.

 Gleyber Torres - SS, NYY at LAA ($3,900)

Torres has rolled up some decent numbers vs. RHP. While his .269 average is just so-so, he has four doubles, four homers and eight RBI in 67 at-bats against righties, and he could be in for a productive night against Angels RHP Matt Harvey, who has an ugly 0-2 record, 9.64 ERA and 1.82 WHIP, while opponents are hitting a collective .333 against him through 18 2/3 innings across four outings.

 

DraftKings DFS Outfielders

Joey Gallo - OF, TEX at OAK ($5,000)

Gallo doesn't have a great average, but that's not why you grab him in DFS. You grab him for his tremendous power, and it could be on full display against RHP Chris Bassitt, who makes his first start of the season. Gallo has 10 extra-base hits, including six homers, vs. RHP, and he has a .755 slugging percentage and 1.162 OPS.

Tommy Pham - OF, TB vs. KC ($4,300)

Pham enters play with four homers, 10 RBI, nine walks and a solid .297/.387/.484 slash line against right-handed pitching.

MLB DFS News and Injury Alerts




REAL-TIME FANTASY NEWS

Isaac Guerendo

Suffers Torn Pec, Could be Ready by End of Training Camp
Noah Fant

Profiles as a Dynasty Drop Candidate Entering 2026
Rashee Rice

Andy Reid Expects Rashee Rice to be Ready for Training Camp
Jordyn Tyson

Remains Limited in OTAs on Thursday
Tank Dell

Not Participating in Texans OTAs
Jacoby Brissett

Mike LaFleur Not Concerned by Jacoby Brissett's Absence From OTAs
Darnell Washington

Participating in OTAs
Jaylen Warren

Slims Down Over the Offseason
Jaxson Dart

Addresses Teammates to Discuss his Involvement With President Trump
Garrett Wilson

Back at OTAs With Jets
Brock Bowers

Taking Part in OTA Workouts
MLB

MLB Proposes Hard Salary Cap as Part of Next CBA
Xavier Worthy

Limited in OTAs After Having Shoulder Surgery
Patrick Mahomes

Limited to 7-on-7 Drills at OTAs
Joe Burrow

Solidified as a Top Dynasty Quarterback?
Jordan Love

Does Jordan Love Still Have Top-12 Upside in Dynasty?
Dalton Schultz

Can Dalton Schultz Have Another Top-10 Season?
Jayden Higgins

Hype Brewing for a Jayden Higgins Breakout in Year 2
Luther Burden III

Ben Johnson Suggests Buying Stock in Luther Burden III
Kenley Jansen

Tigers Place Kenley Jansen on Injured List With Pelvic Inflammation
A.J. Brown

Eagles, Patriots "Not Particularly Close" to A.J. Brown Deal
Kenyon Sadiq

has Hernia Surgery, Expected to be Ready for Training Camp
Teoscar Hernández

Teoscar Hernandez Heading to Injured List With Hamstring Strain
Treylon Burks

A Treylon Burks Dynasty Resurgence Looking Highly Unlikely
Cedric Coward

Aims to Improve Ball-Handling Ability
Jonas Valančiūnas

Jonas Valanciunas Attracting Interest From Europe
Giannis Antetokounmpo

Celtics Reportedly Not Interested in Giannis Antetokounmpo
LeBron James

Reportedly Waiting for Lakers Approach
MON

Lane Hutson Struggles in Game 4 Loss
CAR

Logan Stankoven Nets Eighth Postseason Goal
CAR

Sebastian Aho Pots Game-Winner on Power Play
CAR

Nikolaj Ehlers Tallies Two Helpers in Impressive Road Win
CAR

Shayne Gostisbehere Records Two Assists in Game 4 Win
CAR

Frederik Andersen Establishes Hurricanes New Postseason Shutout Record
Yordan Alvarez

Continues Homer Barrage With Two More Long Balls on Wednesday
Cristopher Sánchez

Cristopher Sanchez Makes History With Seven More Shutout Innings Against Padres
Teoscar Hernández

Teoscar Hernandez Lifted From Wednesday's Game Early With Hamstring Strain
Kenley Jansen

Exits Relief Appearance on Wednesday With Groin Injury
Mason Plumlee

NBA Upgrades Mason Plumlee's Foul to a Flagrant 1
Victor Wembanyama

Receives Warning From NBA
Atlanta Hawks

Hawks Promote Onsi Saleh to President of Basketball Operations
Jalen Williams

Listed as Questionable for Game 6
Ajay Mitchell

Ruled Out for Game 6
Eury Pérez

Eury Perez Pulled Early on Wednesday With Hamstring Issue
CFB

Drew Mestemaker a Top Big 12 Quarterback Right Away?
PGA

Sungjae Im Remains Boom-or-Bust at Colonial
PGA

Michael Thorbjornsen Trending in Wrong Direction Entering Colonial
De'Aaron Fox

Limited to Nine Points in Game 5 Loss
Russell Henley

a Top Option at Colonial
Harry Hall

Hoping Putter Carries Him at Colonial
Julian Champagnie

Notches 22 Points With Four Triples Tuesday
Stephon Castle

Leads Spurs in Scoring Tuesday Night
Rickie Fowler

Looks to Regain Momentum at Colonial
Victor Wembanyama

Struggles in Game 5 Loss to Thunder
Alex Caruso

a Difference-Maker Again in Game 5
Pierceson Coody

Looking to Stay Hot at Colonial
Jared McCain

Produces 20 Points in First Playoff Start
Shai Gilgeous-Alexander

Scores Game-High 32 Points in Game 5 Win
Martin Necas

Collects an Assist in Game 4 Loss to Golden Knights
Gabriel Landeskog

Scores Only Avalanche Goal in Season-Ending Loss
Carter Hart

Finishes Series-Clincher With 20 Saves
Dylan Coghlan

Continues Unlikely Success Story
Cole Smith

Scores Series-Clincher Tuesday Night
Mark Stone

Nets Another Goal as Golden Knights Finish Off Avalanche
Ludvig Aberg

Looking to Exchange Momentum for a Victory in Fort Worth
Stephan Jaeger

Trending Upward as PGA Heads to Fort Worth
Max Homa

Comes Off Awful Putting Performance at PGA Championship
Tony Finau

Faces Different Test at the Colonial
Robert MacIntyre

Seeks Better Beginning in Fort Worth
Tom Hoge

Ups and Downs Could Continue at Colonial
Brian Harman

Not Having the Best Golf Season in 2026
Austin Eckroat

Struggling Too Often Heading to Charles Schwab Challenge
Zach Bauchou

Tries to Keep Momentum Rolling at Colonial
Keegan Bradley

Looking to Rebound at Colonial
Jared McCain

Moves into Starting Five
Boston Celtics

Joe Mazzulla Wins Coach of the Year
Jalen Williams

is Ruled Out for Game 5 on Tuesday
Zion Williamson

to See More Versatile Role
Cleveland Cavaliers

Kenny Atkinson to Remain Cavaliers Head Coach Next Season
Claude Giroux

Planning to Return for 20th NHL Campaign
Carter Hart

Aiming for Sixth Consecutive Win Tuesday
Evgeni Malkin

Inks New One-Year Deal With Penguins
Mackenzie Blackwood

in Net for Game 4 Against Golden Knights
Valeri Nichushkin

a Game-Time Call Tuesday
Nathan MacKinnon

Will Suit Up Tuesday
Ben Griffin

Looking to Repeat This Week at Colonial
Rasmus Hojgaard

a Player to Avoid at Charles Schwab Challenge
Hideki Matsuyama

Needs Solid Driving Week at Charles Schwab Challenge
Justin Thomas

Trending Well Ahead of Charles Schwab Challenge
Akshay Bhatia

Lacking Driving Prowess Needed at Colonial Country Club
CFB

DJ Lagway Looking to Rebound at Baylor
CFB

Josh Hoover Tasked With Leading Indiana Back to the Playoffs
CFB

Braylon Staley the Next 1,000-Yard Tennessee Receiver?
CFB

Ahmad Hardy's Return Timeline Remains Unclear
Ivan Demidov

Contributes an Assist in Losing Effort
Lane Hutson

Records Power-Play Goal in Game 3 Loss
Frederik Andersen

Enjoys Another Easy Night at the Office in Game 3
Gage Jump

Athletics to Promote Top Pitching Prospect Gage Jump to Major Leagues
Tatsuya Imai

Two Relievers Combine to No-Hit the Rangers on Monday
Dylan Cease

Heading to Injured List With Hamstring Injury
Daniel Suarez

Wins at Charlotte in Rain-Shortened Coca-Cola 600
Christopher Bell

Finishes as the Runner-Up in the Coca-Cola 600 at Charlotte
Denny Hamlin

Falls Short of Winning and Places Third at Charlotte
Tyler Reddick

Places Fourth After Leading Laps at Charlotte
Kyle Larson

Strong and Consistent Day Ends in Fifth at Charlotte
Dylan Cease

Removed From Sunday's Start With Hamstring Discomfort
Vladimir Guerrero Jr.

Exits Sunday's Game Early with Elbow Contusion
MLB

Reds-Cardinals Game Postponed on Sunday
Edward Cabrera

Cubs Place Edward Cabrera on the 15-Day Injured List
Denny Hamlin

the Favorite to Win at Charlotte
Tyler Reddick

on Pole for Coca-Cola 600
Christopher Bell

Could Break Out of Slump
Kyle Larson

May have A Solid Day at Charlotte
Ryan Blaney

Is A DFS Risk for Charlotte Lineups
William Byron

Could have A Great DFS Performance at Charlotte
Chase Briscoe

Is A Solid Tournament Option for Charlotte DFS Lineups
Ty Gibbs

May not be Worth his Salary for Charlotte DFS Lineups
Chris Buescher

May be a Sneaky Tournament Option for Charlotte Lineups
NASCAR

Bubba Wallace Has Favorable Upside for Charlotte DFS Lineups
Ross Chastain

Is A Strong Addition for DFS Lineups at Charlotte
Austin Dillon

Should Fantasy Managers Roster Austin Dillon for Charlotte DFS Lineups?
Chase Elliott

Should Be Strong at Charlotte
Carson Hocevar

Confident for Coca-Cola 600
Corey Heim

a Chalk DFS Pick at Charlotte
Michael McDowell

Is Michael McDowell A Tournament Option for Charlotte Lineups?
MLB

Orioles-Tigers Game Postponed on Saturday
MLB

Rays-Yankees Postponed on Saturday
Mickey Moniak

Heads to Injured List With Ankle Sprain
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF