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DraftKings Daily Fantasy Baseball Picks (4/22/19): MLB DFS Lineups

The top daily fantasy baseball lineup picks for DraftKings on April 22nd, 2019. Daniel E. Dobish's MLB DFS analysis and sleepers for building optimal DFS rosters.

For Monday's slate of Major League Baseball games, I'll focus on the contests (first pitch of 7:05 PM EST and later). Be sure to double-check the weather and the lineups before finalizing your roster.

There will be some possible light rain affecting the start of the Philadelphia Phillies-New York Mets battle, although the game should get started with minimal interruption. At Fenway Park, the Detroit Tigers-Boston Red Sox game has a 70 percent or greater chance of rain all day, so it's likely we'll have a postponement in that game. If they do get underway they will face a stiff 11-14 mph wind blowing in directly from center field to home plate. It's best to avoid all Tigers and Red Sox just to be on the same side. Wind will be a factor at Busch Stadium for the Milwaukee Brewers-St. Louis Cardinals battle, blowing 12-15 mph out to left field.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 4/22/19. The lineup picks will range from some of the elite players to mid-priced options and value plays. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. Be sure to also check out all the Vegas Odds for today's slate. If you have any questions or comments, contact me on Twitter @danieledobish.

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DraftKings DFS Starting Pitchers

Yonny Chirinos - P, TB vs. KC ($7,400)

Chirinos has piled up 17.5 Fantasy Points Per Game (FPPG), yet he flies under the radar with a low salary. Take advantage. While he was torched in a start April 12 in Toronto, allowing six earned runs in just 2 1/3 innings, he has won his other three appearances while allowing a total of just one earned run and five hits in 17 innings. Overall he has posted a 0.83 WHIP, and he has just four walks to 19 strikeouts over 19 1/3 innings.

Brad Peacock - P HOU vs. MIN ($8,200)

The Astros enter play with a 7-3 mark across their past 10 games against right-handed starting pitching, and they're 6-1 in Peacocks' past seven starts overall, and 6-1 in his past seven home outings, too. Conversely, the Twins are just 1-8 in their past nine road outings, and 1-10 in his past 11 road starts against teams with a winning overall mark. That bodes well for Peacock's outlook on Monday night, and his 0.81 WHIP across two starts and four outings doesn't hurt, either.

 

DraftKings DFS Infielders

Yasmani Grandal - C, MIL at STL ($4,100)

Grandal has been raking, checking in fifth among all catchers with a .338 average (22-for-65) with two doubles, five homers and 10 RBI. He also ranks second among all backstops in runs scored (14), behind only Seattle's Omar Narvaez, and Grandal is one of just two catchers with an OPS over 1.013 or higher.

Trey Mancini - 1B, BAL vs. CWS ($4,900)

Mancini will get a crack at LHP Manny Banuelos, and that should bode well for him and his owners. He is slashing a robust .379/.455/.759 with five doubles and two homers in 29 at-bats against left-handed starting pitchers.

Kolten Wong - 2B, STL vs. MIL ($4,400)

You'll want plenty of Cards and Brewers with a Jetstream blowing out to left field. Wong has managed a solid .320/.444/.600 slash line vs. right-handed pitching, collected seven extra-base hits with 10 RBI, 10 walks and 10 strikeouts while also adding 10 runs scored.

Yoan Moncada - 3B, CWS at BAL ($4,900)

Moncada has been one of the most consistent hitters from the hot corner, posting a .322 average with three doubles, six homers and 13 RBI vs. RHP, also posting 13 runs scored. While he has managed 18 strikeouts in just 59 at-bats, the power numbers make him worth using most nights. That's especially true against O's RHP David Hess, who enters with a subpar 5.57 ERA across 21 innings.

 Gleyber Torres - SS, NYY at LAA ($3,900)

Torres has rolled up some decent numbers vs. RHP. While his .269 average is just so-so, he has four doubles, four homers and eight RBI in 67 at-bats against righties, and he could be in for a productive night against Angels RHP Matt Harvey, who has an ugly 0-2 record, 9.64 ERA and 1.82 WHIP, while opponents are hitting a collective .333 against him through 18 2/3 innings across four outings.

 

DraftKings DFS Outfielders

Joey Gallo - OF, TEX at OAK ($5,000)

Gallo doesn't have a great average, but that's not why you grab him in DFS. You grab him for his tremendous power, and it could be on full display against RHP Chris Bassitt, who makes his first start of the season. Gallo has 10 extra-base hits, including six homers, vs. RHP, and he has a .755 slugging percentage and 1.162 OPS.

Tommy Pham - OF, TB vs. KC ($4,300)

Pham enters play with four homers, 10 RBI, nine walks and a solid .297/.387/.484 slash line against right-handed pitching.

MLB DFS News and Injury Alerts




REAL-TIME FANTASY NEWS

Philadelphia Eagles

Eagles Offense to Borrow From Kyle Shanahan, Sean McVay in 2026?
Taysom Hill

Saints Haven't Offered a Contract to Taysom Hill
Kayshon Boutte

Working Out Away From the Team
Lamar Jackson

Expected to Return to OTAs Soon
Dalton Kincaid

Taking Part in OTAs This Week
Josh Allen

"Good to Go" for Offseason Workouts
Yandy Díaz

Yandy Diaz Exits Early on Tuesday After Being Hit By Pitch
Rashee Rice

to Miss Two Months After Clean-Up Surgery on his Knee
Dean Wade

Returns to Starting Unit Tuesday
OG Anunoby

Starting on Tuesday
Tobias Harris

May Remain in Motown
Jalen Duren

Pistons Eager to Keep Jalen Duren
Chris Kirk

Continues Search For Putting Form at TPC Craig Ranch
Dallas Mavericks

Jason Kidd Fired as Mavericks Head Coach
De'Aaron Fox

Officially Listed as Questionable for Game 2 Against Thunder
Rasmus Hojgaard

Looking to Shake Off Poor Major Showing at TPC Craig Ranch
Joel Dahmen

is of No DFS Consideration This Week in Dallas
Pierceson Coody

is Not The Fun DFS Play He Used to Be
Tank Bigsby

Is Tank Bigsby a Worthy Dynasty Stash Entering 2026?
Hunter Henry

Profiles as a Dynasty Sell-High Candidate Entering 2026
Gerrit Cole

to Make Season Debut on Friday Against Rays
Matthew Golden

Can Matthew Golden Re-Establish His Dynasty Value in 2026?
Jalen Coker

a Prime Buy-Low Dynasty Target
Dak Prescott

Remains a High-Floor Dynasty Quarterback
CeeDee Lamb

Is CeeDee Lamb's Dynasty Value Poised to Rise in 2026?
Keon Coleman

Joe Brady Likes What he's Seen From Keon Coleman
Deshaun Watson

Hitting it Off With Todd Monken?
Jacoby Brissett

Not Present for First OTA Practice
Tua Tagovailoa

Michael Penix Jr. Splitting First-Team Reps at OTAs
Rashee Rice

Tests Positive for Marijuana, Violating his Probation
Cam Skattebo

Says he'll be Ready for Week 1
De'Von Achane

Present for Start of OTAs This Week
Malik Washington

an Affordable Trade Target in Dynasty Leagues
Drake Baldwin

Braves Place Drake Baldwin on Injured List With Oblique Strain
CFB

Ezavier Crowell has Immediate Opportunity at Alabama
CFB

Mark Bowman a Day 1 Impact Player for USC?
CFB

Bill Belichick Says Relationship with First North Carolina Team "Wasn't Great"
Alex Caruso

Erupts for 31 Points in Game 1 Loss to Spurs
CFB

Kemario Taylor a Breakout Candidate at Quarterback
Jalen Williams

Productive in Comeback Game
CFB

Trinidad Chambliss the Undisputed Top SEC Quarterback Entering 2026?
Shai Gilgeous-Alexander

Records First Double-Double of Postseason
CFB

Rocco Becht The "Unifier" of Penn State's Roster
Stephon Castle

Opens Conference Finals With Double-Double
Dylan Harper

Makes Outstanding Two-Way Impact in Game 1 Win
Victor Wembanyama

Dominates Game 1 Against Thunder
Mattias Samuelsson

Picks Up an Assist in Season-Ending Loss
Rasmus Dahlin

Nets Fourth Postseason Goal
Jakub Dobes

Records 37 Saves in Game 7 Win
Lane Hutson

Contributes Power-Play Assist in Game 7 Victory
Nick Suzuki

Extends Road Point Streak
Alex Newhook

Scores Series-Clincher in Overtime
Jackson Holliday

Orioles Reinstate Jackson Holliday From Injured List on Monday
Ronald Acuña Jr.

Braves Reinstate Ronald Acuna Jr. From Injured List on Monday
Jose Altuve

Astros Put Jose Altuve on Injured List With Oblique Strain
Larry Nance Jr.

is Questionable for Game 1 on Tuesday
OG Anunoby

is Probable for Tuesday's Game 1
Luke Kornet

is Cleared for Game 1
New Orleans Pelicans

Jamahl Mosley Agrees to Become Pelicans Next Head Coach
De'Aaron Fox

is Ruled Out for Game 1 on Monday
Ukko-Pekka Luukkonen

Set to Start Game 7
Corey Seager

Going on Injured List With Back Injury
Tage Thompson

Can Match Franchise Record With Another Multi-Point Game
Nick Suzuki

Seeks More Road Success Monday
Lane Hutson

Riding a Five-Game Assist Streak Into Game 7
Filip Gustavsson

Needs Offseason Surgery
Jeremy Peña

Jeremy Pena Reinstated and Starting on Monday Against Twins
Melquizael Costa

Drops Decision At UFC Vegas 117
Arnold Allen

Bounces Back
Daniel Santos

Suffers Second-Round TKO Loss
MMA

Dohoo Choi Wins His Third Consecutive Fight
Malcolm Wellmaker

Suffers His Second Loss In A Row
Juan Diaz

Scores Second-Round Submission
Christian Edwards

Defeated At UFC Vegas 117
CFB

Transfer Running Back Arnold Barnes Visiting Iowa State on Monday
Modestas Bukauskas

Gets Split-Decision Win
Jhostynxon Garcia

Expected to Join the Pirates on Tuesday
Tobias Harris

Goes Cold in Game 7 Loss
Quinn Hughes

Open to Signing Extension This Offseason
Jalen Duren

Finishes Game 7 with Quiet Line
Cade Cunningham

Endures Cold Shooting Night Sunday
Joel Eriksson Ek

Misses Second Round Due to Heel Injury
Sam Merrill

Catches Fire in Game 7 Win
Jonas Brodin

Sits Out Round 2 Due to Toe Injury
Sam Malinski

Practices Fully Sunday
Josh Manson

Rejoins Practice
Colt Emerson

Mariners Promoting Top Prospect Colt Emerson to Major Leagues
Munetaka Murakami

Fantastic First Season Continues With Two More Homers
Cristopher Sánchez

Cristopher Sanchez Dazzles With 13-Strikeout Complete Game on Saturday
Blake Snell

to Undergo Elbow Surgery on Tuesday
Clay Holmes

Could Miss Around Three Months
Jose Altuve

Exits After Swing
Corey Seager

Absent With Back Spasms on Saturday
Jeremy Lauzon

Misses Saturday's Practice
Mark Stone

Doesn't Practice Saturday
Josh Manson

Misses Practice, Considered Day-to-Day
Brent Burns

Day-to-Day Ahead of Conference Finals
Cale Makar

Considered Day-to-Day
Trevor Story

Hits the Injured List With Groin Injury
Blake Snell

Likely to Need Elbow Surgery
Kyle Schwarber

on a Heater, Hits Two More Homers to Take Major-League Lead
Clay Holmes

Suffers Fractured Fibula on Friday Night
Blake Snell

Heads to 15-Day Injured List
CFB

Julian Sayin Looking To Build Off Of Strong Debut Season
CFB

College GameDay Set for First Three Weeks
CFB

Jeremiah Smith Aiming For Ohio State Receiving Records
CFB

Keshaun Singleton Projects as Auburn's WR1
CFB

Jeremiah Cobb Impresses New Auburn Staff
CFB

Alberto Mendoza Very Likely to Start for Georgia Tech
CFB

Charles Woodson Jr. Commits to Michigan
Melquizael Costa

Set For UFC Vegas 117 Main Event
Arnold Allen

A Favorite At UFC Vegas 117
Daniel Santos

Set For UFC Vegas 117 Co-Main Event
MMA

Dohoo Choi Returns At UFC Vegas 117
Juan Diaz

Set To Make His UFC Debut
Malcolm Wellmaker

Looks To Bounce Back
Christian Edwards

Set For His UFC Debut
Modestas Bukauskas

Looks To Get Back In The Win Column
CFB

Virginia Tech Lands Commitment from Four-Star QB Peter Bourque
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF