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Who Should I Start for Week 16? Fantasy Football outlooks for Travis Etienne Jr., DK Metcalf, George Pickens, Tetairoa McMillan, Luther Burden III, Emeka Egbuka, Rashee Rice, DeVonta Smith, Zay Flowers.
Who Should I Start? Who Should I Sit? Some of the most common Week 16 fantasy football lineup decisions involve players like Travis Etienne Jr., DK Metcalf, George Pickens, Tetairoa McMillan, Luther Burden III, Emeka Egbuka, Rashee Rice, DeVonta Smith, Zay Flowers. However, don't worry, we are here to help you make these decisions and build winning lineups in Week 16. Set your optimal fantasy football lineups for Week 16 of the 2025 NFL season. Our free Who Should I Start? tool will help make your fantasy football lineup decisions. Compare up to four NFL players, and we tell you who to start... all free! Get your winning lineups set, and make the right decisions.
Compare up to four players and we'll tell you who to start...
Fantasy Football Matchup Outlooks
Below are some fantasy football outlooks written by our NFL team here at RotoBaller, bringing you their fantasy football analysis and advice on which players to consider starting in Week 16:
Travis Etienne Jr., RB, Jacksonville Jaguars
Jacksonville Jaguars running back Travis Etienne Jr. exploded for three receiving touchdowns in the Week 15 blowout win over the New York Jets. Etienne added 12 carries for 32 yards and three catches for 73 yards on four targets in the game. The 26-year-old continued his breakout campaign, becoming the eighth player this season and the first running back with three receiving scores. Etienne entered the game with only three career receiving touchdowns, but he doubled that mark on Sunday.
There have only been four other running backs to record three touchdown catches in a game since 2015. Despite averaging just 3.0 yards per carry over the last three games, Etienne has totalled the fourth-most PPR points among running backs (57.8) during that stretch. He is firmly entrenched as one of the best weekly running back options in fantasy, even in a tough Week 16 matchup against the Denver Broncos.
Tetairoa McMillan, WR, Carolina Panthers
Carolina Panthers rookie first-round wide receiver Tetairoa McMillan logged his worst performance of the year in the Panthers' loss to the Saints in Week 15. The first-round rookie caught two passes for 25 yards, totaling 4.5 PPR points in the first round of the fantasy playoffs in most leagues. This was the first time this year that McMillan posted less than 5.0 PPR points, and it was also the first time he had not scored a touchdown since Week 10. The Carolina Panthers take on the Tampa Bay Buccaneers in Week 16.
In the last four weeks leading up to Week 15, Tampa Bay ranked 18th in fantasy points per game allowed to WRs. McMillan has been targeted less than five times in each of his last two games, but he has a decent matchup for Week 16. He has averaged 7.2 targets per game this season. McMillan's possible volume still makes him startable as a WR3 or flex option for Week 16. He could see more targets in the major NFC South showdown against the Buccaneers.
Luther Burden III, WR, Chicago Bears
With Odunze sidelined in Week 15, Burden III recorded six catches for 84 yards on seven targets despite being limited to just 29 offensive snaps due to the ankle injury. Burden III's role has been steadily growing over the second half of the season, as he's earned at least five straight targets in five straight games after failing to hit that mark in any of his first eight contests. Depending on Odunze's return timeline and his own health, Burden III could emerge as a league-winner over the final weeks of the fantasy season.
Who Should I Start Tool
You can also see the Who Should I Start tool here.
Week 16 Player Decisions. Today's focus is on specific players - Travis Etienne Jr., DK Metcalf, George Pickens, Tetairoa McMillan, Luther Burden III, Emeka Egbuka, Rashee Rice, DeVonta Smith, Zay Flowers. These are some of the most common searches for fantasy football lineups in Week 16.
Using The Tool. This is a simple tool but very powerful. The first step is to enter the player names that you want to compare. In the first box, search for the first player name. In the second box, search for the second player name. Compare up to four NFL players at once, and then click the Who To Start? button to see who the recommended starts are based on weekly fantasy football matchups.
Improvements For Who Should I Start? You may have noticed that our 'Who Should I Start?' tool has gotten an overhaul. We've added lots of great features for you to give you as much information as possible to win your fantasy football matchups each week. You'll see NFL player tiles with headshots and bye weeks, stats, projections, strength of schedule, players news, and enhanced search results with data to compare with a slick new interface. We hope you enjoy!
How It Works. Each week our RotoBaller staff puts together their weekly fantasy football rankings and projections based on their research. That information is the core data that is powering the decision-making in this tool. When you search for player names, you will only see those players who are ranked. If someone is out for the week, they will not appear in the search results.
Scoring Formats. Fantasy football managers play in various types of leagues, and this tool allows you to choose whether it's PPR scoring, Half-PPR scoring, or Standard (Non-PPR) scoring. The second thing you want to do, is to select the scoring format. There are three small radio buttons (small circle), so click on the scoring format you prefer. The results may vary based on the scoring format you select.
Popular Week 16 Searches. Curious to see some tough lineup decisions for Week 16 (2025)? Below you will find a list of some popular Who Should I Start? searches that RotoBaller readers are looking at this week. Click any of the links to see the result and recommendation.
Popular Week 16 Searches - Start/Sit Player Comparisons
Below are some popular searches and comparisons from our Who To Start tool for Week 16 for Travis Etienne Jr., DK Metcalf, George Pickens, Tetairoa McMillan, Luther Burden III, Emeka Egbuka, Rashee Rice, DeVonta Smith, Zay Flowers:
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