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San Francisco 49ers left tackle Trent Williams (hamstring) exited during the first quarter of Sunday Night Football against the Chicago Bears in Week 17. He is officially listed as questionable to return. Williams had only missed 13 snaps during the 2025 season prior to Week 17. He is widely regarded as one of the best offensive linemen in NFL history, so the 49ers will hope his absence is brief. Similarly, fantasy managers who roster Brock Purdy and Christian McCaffrey will hope that Williams can get back into the game very soon. In the meantime, Austin Pleasants will take over at left tackle, protecting Purdy's blindside.--Andersen Pickard
Source: San Francisco 49ers
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