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Oct 17, 2026, 9:16 PM ET

Oregon star wide receiver Evan Stewart (undisclosed) has been ruled out of Saturday night's game against Nebraska. Stewart was downgraded to doubtful on Thursday's injury report. The senior wide receiver is leading the Ducks with 27 catches, 352 receiving yards, and four touchdowns. It's unclear whether Stewart will miss any additional games because of this injury.--Chris Blomstrand
Source: Big 10 Availability Report
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Oct 17, 2026, 9:15 PM ET

Orlando Magic forward Franz Wagner (shoulder) remains under evaluation after leaving Friday's preseason finale against Miami with right shoulder soreness, according to the Orlando Sentinel's Jason Beede. Wagner appeared bothered by the shoulder after a three-point attempt in the third quarter and finished with 11 points, six rebounds, and six assists in 19 minutes. The 25-year-old averaged 20.6 points and 5.2 rebounds in only 34 games last season, so another injury is worth monitoring. If Wagner can't play Wednesday against Atlanta, Tristan da Silva should be in line for more minutes with Noah Penda (hamstring) also sidelined.--Brian Dailisan
Source: Jason Beede
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Oct 17, 2026, 9:13 PM ET

San Francisco 49ers wide receiver Mike Evans (ribs, Achilles) is currently listed as questionable ahead of Monday's Week 6 matchup against the Washington Commanders. Evans has been working on the side during each of the last two practices while nursing ribs and Achilles injuries. According to Larry Krueger, Evans looks like he's on the wrong side of questionable heading into Monday's game. The 49ers should give another update on his status soon. If Evans is unable to play, Brandin Cooks, Jacob Cowing, and Jordan Watkins would be the starting wideouts for Monday's game. Fantasy managers should stay tuned for more updates ahead of Monday's game.--Andy Webb
Source: Larry Krueger
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Oct 17, 2026, 9:09 PM ET

Orlando Magic forward Noah Penda (hamstring) is expected to miss significant time after partially tearing his right hamstring in Friday's preseason finale against Miami, according to the Orlando Sentinel's Jason Beede. The 21-year-old left late in the first quarter after just two minutes, finishing with one steal. The tear is reportedly a separate injury from the hamstring issue that slowed him earlier in camp. Penda averaged 3.8 points and 3.2 rebounds in 12.8 minutes as a rookie. Tristan da Silva and Jamal Cain could see more wing minutes while Penda is out, especially if Franz Wagner (shoulder) also misses time.--Brian Dailisan
Source: Jason Beede
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Oct 17, 2026, 9:01 PM ET

Los Angeles Clippers center Isaiah Jackson will open the season as the team's starting center, according to The Athletic's Law Murray. Head coach Tyronn Lue named Jackson the Week 1 starter, with Brook Lopez moving into the backup role. The 24-year-old averaged 7.5 points, 4.6 rebounds, and 1.2 blocks in 15.9 minutes across 17 games with the Clippers last season while shooting 76.4% from the field. Lue likes the speed Jackson brings at center, and a jump in minutes could make him useful for rebounds, blocks, and efficient scoring starting Wednesday against Sacramento.--Brian Dailisan
Source: Law Murray
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Oct 17, 2026, 8:52 PM ET

Florida State sophomore running back Ousmane Kromah (lower body) was carted off the field Saturday night with a lower-body injury in the game against No. 3 Miami. The injury appears severe; the entire Florida State team came onto the field to comfort the star running back. This season, Kromah led the Seminoles' backfield, taking 100 carries for 565 rushing yards and five touchdowns. He also added 11 catches for 97 receiving yards. Florida State will likely turn to transfer senior Quintrevion Wisner in Kromah's absence. This season, Wisner has 29 carries for 141 rushing yards and 8 catches for 95 receiving yards.--Chris Blomstrand
Source: ACC Network
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Oct 17, 2026, 8:30 PM ET

Alabama junior cornerback Zabien Brown (lower body) left Saturday's 10-26 loss to No. 14 Tennessee early due to a lower-body injury. Brown left the game in the first half and was evaluated at halftime; he returned in the second half wearing street clothes. After the game, Alabama head coach Kalen DeBoer stated he is dealing with a lower-extremity injury and did not discuss a timeline for his return. This season, Brown has 17 tackles, one fumble recovery, and four pass deflections; he is a consensus top-10 cornerback prospect for the 2027 draft.--Chris Blomstrand
Source: Mike Rodak Of CBS Sports
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Oct 17, 2026, 7:55 PM ET

Notre Dame star cornerback Leonard Moore (head) cleared concussion protocol just in time to play against No. 8 BYU on Saturday night. The junior missed last week's game against Stanford due to the concussion, but he is back in action for the Fighting Irish on Saturday. Moore is expected to be the first cornerback off the board in the 2027 NFL draft if he decides to forgo his senior season. This season, Moore has eight tackles, four pass deflections, and has yet to record an interception, likely because opposing quarterbacks avoid his side of the field entirely.--Chris Blomstrand
Source: Pete Nakos Of On3
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Oct 17, 2026, 7:14 PM ET

Seattle Seahawks Zach Charbonnet (knee) has a legitimate chance to make his season debut in Week 7 against the Kansas City Chiefs, according to Jeremy Fowler of ESPN, who cited multiple sources. Charbonnet tore his ACL during Seattle's divisional-round playoff win over San Francisco in January, and the team opened his 21-day practice window on October 1. With the Seattle backfield in a mess, Charbonnet has a chance to swoop in and take the lead role. Charbonnet has always been viewed as a talented running back, but his value was capped when Kenneth Walker III was on the roster. With Walker in Kansas City, Charbonnet has an opportunity to show the Seahawks he can be the guy. The team did use the No. 32 overall pick on running back Jadarian Price (chest), but he is on Injured Reserve with a chest injury and didn't establish himself as the lead back when healthy. If Charbonnet is on the waiver wire, he should be a priority add and needs to be rostered in all fantasy leagues.--Wyatt McClintock
Source: ESPN - Jeremy Fowler
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Oct 17, 2026, 6:53 PM ET

Arizona Cardinals running back Tyler Allgeier is set to be the team's lead back on Sunday in their Week 6 matchup against the Los Angeles Rams. Jeremiyah Love (ankle) was ruled out, according to team reporter Darren Urban. Love missed Wednesday and Thursday practices, prompting Mike LaFleur to tell reporters that the rookie's injured ankle will require further rest. Allgeier instantly becomes a waiver-wire pickup and can be slotted into fantasy lineups as an RB2. The 26-year-old enters Week 6 as RotoBaller's PPR RB24 against the Rams. The Rams' defense has allowed the sixth-most rushing yards this season and recently surrendered 111 rushing yards to James Cook on Monday Night Football. Allgeier is no stranger to fantasy points when given heavy volume and should be in fantasy lineups in Week 6.--Wyatt McClintock
Source: ESPN.com - Darren Urban
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Oct 17, 2026, 6:36 PM ET

Minnesota Vikings running back Jordan Mason (thumb) is expected to return to action after the team's Week 6 bye, according to ESPN's Kevin Seifert. The 27-year-old was placed on Injured Reserve with a fractured thumb after the team's Week 1 victory over the Green Bay Packers. Mason has missed his required four games after landing on Injured Reserve and will get an additional week because of the bye. During Mason's absence, Aaron Jones Sr. has handled the majority of the work and has been the PPR RB11 in overall scoring, averaging 15.1 points per game. Jones' production should give Mason managers hope that he can become a solid fantasy asset for the remainder of the season. However, it will be interesting to see how the team utilizes both backs when Mason returns. If Mason is on the waiver wire, he is a worthy bench stash until he returns to the lineup.--Wyatt McClintock
Source: ESPN.com - Kevin Seifert
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Oct 17, 2026, 6:19 PM ET

Carolina Panthers wideout Brycen Tremayne has made the most of his expanded role over the last two games. The 26-year-old has hauled in six of his nine targets for 115 receiving yards and has seen over an 80 percent snap percentage during that stretch. However, Tremayne likely saw his role increase because Jalen Coker missed time with a quad injury. Coker is set to return to action in Week 6 and will cut into Tremayne's workload. Tremayne enters Week 6 as RotoBaller's PPR WR81 in a matchup against the Philadelphia Eagles. The Eagles defense has been thrown on the seventh-most and allowed the 11th-most receiving yards this season. Tremayne should be out of lineups because of a tough defensive matchup and more target competition for Week 6.--Wyatt McClintock
Source: NFL.com
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Oct 17, 2026, 5:59 PM ET

The San Francisco 49ers' D/ST put up their best fantasy production to date in Week 5 despite giving up 29 points in the team's win over the Seahawks. The unit's success was driven by San Francisco's five sacks, one interception, and two fumble recoveries, including one in Seattle's end zone for a touchdown. A boom week like that will be hard to follow, especially with the losses in personnel the 49ers will have in Week 6. Linebacker Dre Greenlaw will serve a one-game suspension for an illegal headbutt last week, and Joey Bosa (knee, calf) will need at least one more week to recover before returning to action. Additionally, defensive back Upton Stout (shoulder) and lineman Mykel Williams (knee) are questionable. The Commanders have done well at protecting the ball but allowed five sacks last week and are in the middle of the pack with 23 points scored per game. San Francisco doesn't make for an elite option, but they will be a serviceable streamer in Week 6.--Dan Stephens
Source: NFL.com
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Oct 17, 2026, 5:55 PM ET

San Francisco 49ers kicker Eddy Pineiro missed a field goal attempt from 52 yards out but was good on his 44-yard try that ended up being the difference in last week's 32-29 win over the Seahawks. He was 3-for-3 on extra point attempts, as well. The 49ers' efficiency on offense has eaten into Pineiro's production in 2026, allowing him just eight field goal attempts (with five makes) through the first five weeks. Pineiro could see more action this week, though. The 49ers' upcoming meeting with the Commanders has one of the highest point totals on the Week 6 slate. If the offensive bonanza comes to fruition, it will put Pineiro in a good spot for some extra chances to put points on the board. Pineiro has a top-12 projection in Week 6, and fantasy managers can feel good about including him in starting lineups.--Dan Stephens
Source: NFL.com
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Oct 17, 2026, 5:52 PM ET

Ole Miss running back Kewan Lacy (lower body) is back in against Missouri on Saturday. Lacy has been in and out of the medical tent all game and missed a full drive for the Rebels, but he's back in. Lacy has turned eight carries for 64 rushing yards and one catch for four yards on Saturday, and with the Rebels up 21-3 midway through the third quarter, they may sit Lacy as a precaution if they think they've got the game locked up.--Chris Blomstrand
Source: Pete Nakos Of On3
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