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San Francisco 49ers pass-rusher Nick Bosa (knee) will not return to Sunday's Week 3 contest against the Arizona Cardinals. The team initially listed him as questionable before downgrading him to out during the second half. At the time of his departure, he had made two tackles and also forced a fumble. Bosa is the heart and soul of the 49ers' defense, so the unit might take a step backward for the duration of his absence. To make matters worse, San Francisco is also without Mykel Williams (wrist, questionable). Yetur Gross-Matos and Bryce Huff should earn more defensive snaps for the time being.--Andersen Pickard
Source: Adam Schefter
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REAL-TIME FANTASY NEWS

Colston Loveland

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Tre Tucker

Explodes for Three Touchdowns in Absurd Outing Sunday
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Questionable to Return Against Raiders in Week 3
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Active for Week 3
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Officially Ruled Out for Week 3
Cedric Coward

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Trevor Megill

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Goes on 15-Day Injured List With Lat Strain
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Back in Lineup on Sunday
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Jaxon Smith-Njigba

Expected To Play In Week 3
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Targeting Week 7 Return
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