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Dallas Cowboys quarterback Dak Prescott is coming off back-to-back fantasy finishes outside the top 12 at the position, and in Week 16, he faces a Chargers defense that has been the third-toughest matchup for opposing quarterbacks. While the deck may seem stacked against him, Prescott remains a strong play for the fantasy semifinals. Both CeeDee Lamb (illness) and Javonte Williams (neck) were able to log full participation at Friday's practice after beginning the week limited, giving Prescott his full complement of offensive weapons for a game with the second-highest over/under of the week. Notwithstanding his recent mini-slump, in which he's thrown only one touchdown over the past two weeks, Prescott is still averaging 336 passing yards per game across his last four outings, despite facing three of the league's five best passing defenses in that span. He is RotoBaller's QB4 for the week.--Patrick McGrath
Source: RotoBaller
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REAL-TIME FANTASY NEWS

Rui Hachimura

Questionable Versus the Clippers
Al Horford

to Miss More Time With Back Injury
Seth Curry

Ruled Out vs Suns
Peyton Watson

Questionable Saturday Against Rockets
Tristan da Silva

Uncertain for Saturday Against Jazz
Jrue Holiday

Ruled Out Against Sacramento
Tari Eason

Still Sidelined Saturday vs Nuggets
Zach Bogosian

Unavailable Saturday
Marcus Johansson

Questionable for Saturday
Bo Horvat

to Miss Fourth Straight Game Saturday
Seth Jarvis

to Be "Out for a While"
Phillip Danault

Rejoins Canadiens for Draft Pick
Mason Marchment

Blue Jackets Acquire Mason Marchment
Ja Morant

to Miss Second Straight Game Saturday
Brandon Lowe

Pirates Acquire Brandon Lowe in Three-Team Trade
RJ Barrett

to Remain Out Saturday
Jakob Poeltl

Facing Another Potential Absence Saturday
Jerami Grant

Picks Up Questionable Tag
Deandre Ayton

to Miss Matchup Against Clippers Saturday
Lauri Markkanen

Unlikely to Play Saturday
Klay Thompson

Iffy for Saturday
Anthony Davis

Expected to Play Saturday
James Harden

Available Saturday
Domantas Sabonis

to Miss 4-5 More Weeks
Anthony Edwards

Returns Without Minutes Restriction Friday
Zach Collins

Upgraded to Available Friday
Tre Jones

Available With Minutes Restriction
Ayo Dosunmu

Returns From Three-Game Absence
Shane Baz

Orioles Acquire Shane Baz From the Rays
Jonathan Marchessault

Out Day-to-Day
Tristan Jarry

Oilers Place Tristan Jarry on Injured Reserve
Patrick Kane

to Remain Out Saturday
Shea Theodore

Considered Week-to-Week
Jack Eichel

to Miss at Least Two More Games
Davante Adams

Likely Won't Play in Week 17
Jordan Martinook

Misses Friday's Contest
Evan Rodrigues

Available Against Hurricanes
Tyler Seguin

Undergoes Surgery, to Be Re-Evaluated After Olympics
Marvin Harrison Jr.

Listed as Questionable for Week 16
Drake London

Expected to Play Sunday
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Questionable to Play in Week 16
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Will Start at RB in Week 16
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Will Practice on Friday, Expected to Play on Sunday
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Shelved for Remainder of 2025
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Darian Mensah Returning to Duke Next Season
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Josh Hoover Linked to Indiana in Transfer Portal
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Arch Manning Agrees to Reduced Compensation for 2026 Season
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Collects Second Shutout of the Season
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Blanks Penguins Thursday
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to Miss 6-8 Weeks With Broken Leg
Tristan Jarry

Sustains Lower-Body Injury Versus Bruins
Anthony Cirelli

Injured in Thursday's Loss
Kenneth Walker III

Breaks Off Long Touchdown in Comeback Win vs. Rams
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Racks Up Highest Yardage Total in Over a Decade
Puka Nacua

Delivers Career-Best Performance on Thursday Night Football
Michael King

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Logan Webb

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Tarik Skubal

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Jakobi Meyers

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Davante Adams

Officially Out on Thursday Night
Devin Neal

Placed on Injured Reserve, Will Not Return in 2025
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Will Muschamp Becoming Next Texas Defensive Coordinator
Christian Watson

Questionable for Week 16
Josh Jacobs

Listed as Questionable for Saturday Night
T.J. Watt

Unlikely to Play in Week 16
D'Andre Swift

Questionable to Face the Packers
Rome Odunze

Ruled Out for Week 16
Jawhar Jordan

Could be in for Significant Workload Against Raiders
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Expected to Miss Third Straight Game
CFB

Beau Pribula Set to Enter Transfer Portal
Josh Jacobs

Expected to Play in Week 16
Bo Bichette

Willing to Make the Move to Second Base
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Jeremiyah Love Officially Heading to NFL Draft
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Jake Merklinger Leaving Tennessee for Transfer Portal
Mike Trout

Angels Open to Mike Trout Playing Center Field in 2026
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Kansas State's Jayce Brown Intends to Transfer
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Nation's Leading Passer Drew Mestemaker to Enter Transfer Portal
Justin Crawford

Phillies Planning to Start Justin Crawford in Center Field
CFB

Jayden Maiava Signs New Deal to Return to USC
CFB

Aidan Mizell Won't Return to Florida, Entering Transfer Portal
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East Carolina Targeting Jordan Davis as Next Offensive Coordinator
CFB

Michigan QB Jadyn Davis Set to Enter Transfer Portal
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Travis Williams Joining Texas A&M Defensive Staff
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Dylan Raiola Entering His Name into Transfer Portal
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Cincinnati's Brendan Sorsby Plans to Transfer When Portal Opens
Adolis García

Adolis Garcia, Phillies Finalizing One-Year Deal on Monday
Brandon Royval

Suffers First-Round TKO Loss
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Baylor, LSU, Miami Among Potential Suitors for DJ Lagway
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Aidan Chiles Will Enter Transfer Portal
Manel Kape

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Gets Second-Round Knockout Win
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Suffers His First Career Knockout Loss
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Quarterback DJ Lagway Entering Transfer Portal
Cesar Almeida

Gets Dominated
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Wins Sixth Fight In A Row
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Morgan Charriere Suffers First-Round Knockout Loss
Melquizael Costa

Gets First-Round Knockout Win
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