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The San Francisco 49ers defense, which leads the league in sacks, is facing the Carolina Panthers offense, which has allowed the 10thh-most sacks. Defensive end Nick Bosa, who has had a sack or more in each game, faces his old college rival Baker Mayfield. The last time the two of them squared off was in Bosa's rookie season, two years removed from Mayfield's infamous flag-planting incident, and Bosa came up with two sacks. Bosa refrained from trash talking this time but was quoted by Kyle Terada of KNBR as saying, "I do have a lot of pretty valuable experiences so far, and there are some young guys in the D-line room that I like to share that with." The 49ers are an elite defense that can limit any offense, and the Panthers are a subpar offense, so the 49ers are a clear start in Week 5.--Mitchell Blatt - RotoBaller
Source: Team Rankings
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