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Dennis Clausen highlights the top FanDuel NFL DFS lineup picks for Week 12 of the 2022 season, and some value sleepers for your daily fantasy football rosters.
Week 12 began with a three-game Thanksgiving showdown, although the day didn't go exactly as planned for many DFS participants. While most had expected the Bills to take down the Lions easily, Detroit kept things close for the entire contest. In the end, Buffalo managed to squeak out a victory courtesy of a Tyler Bass field goal.
That game was followed by Dallas and New York meeting in an NFC East clash, with the Cowboys taking the win. After Tony Pollard's monster Week 11 showing, Ezekiel Elliott was surprisingly the more productive back versus the Giants. To close out the evening, the Patriots and Vikings had a shootout that nobody saw coming, with Mac Jones and Kirk Cousins combining for five touchdowns and nearly 700 passing yards. With the win, Minnesota got back on track after losing its previous one to Dallas to remain one of the top teams in the NFC.
In this article, I will be providing you with my Week 12 daily fantasy football lineup picks for FanDuel. These lineups can vary from higher-priced players and elite options to lower-priced players and value picks on FanDuel. Be sure to also check out our weekly DraftKings DFS lineup picks and lots of other great NFL DFS articles and NFL DFS tools to help you win big! Also, feel free to give me a follow on Twitter @DennisMClausen. Let's get started!
Be sure to check all of our fantasy football rankings for 2025:- 2025 fantasy football rankings
- Running back (RB) fantasy football rankings
- Wide receiver (WR) fantasy football rankings
- Tight end (TE) fantasy football rankings
- Quarterback (QB) fantasy football rankings
- FLEX fantasy football rankings
- Defense (D/ST) fantasy football rankings
- Kicker (K) fantasy football rankings
- Dynasty fantasy football rankings
FanDuel Quarterbacks - Week 12 DFS Lineup Picks
Joe Burrow - @ TEN ($8,600)
Burrow threw two touchdowns and four interceptions during the season opener against the Steelers. However, he reversed those numbers in last Sunday's rematch and accumulated 355 yards in the process. Cincy will next take on the Titans, a squad that has done a fine job getting to the quarterback.
At the same time, the Bengals' offensive line has recently been better at keeping Burrow upright, which is a plus. Ja'Marr Chase, who's been out with a hip injury, could return for this one, which would be a bigger plus for Burrow and his fantasy potential.
Justin Herbert - @ ARI ($7,900)
After tossing 38 touchdowns last season, Herbert doesn't appear to have a chance at coming close to that mark. In all fairness, he's been without Mike Williams and Keenan Allen for a good portion of the 2022 campaign, so it's not all his fault. Fortunately, the Chargers will face a Cardinals' defense that has surrendered nine touchdowns through the air over the last four weeks, tying with Green Bay and Pittsburgh for the worst total in the National Football League.
While Williams may not be available in Week 12, Allen will be, which is undoubtedly good news for the signal-caller. Joshua Palmer, who had eight catches for 106 yards and two touchdowns in Week 11, will also be on the field to help make life easier for Herbert versus Arizona.
Also Consider: Patrick Mahomes ($9,000), Tua Tagovailoa ($8,300), Tom Brady ($7,400)
FanDuel Running Backs - Week 12 DFS Lineup Picks
Kenneth Walker III - vs. LV ($8,400)
Walker has had a fantastic inaugural year. The rookie totaled seven touchdowns throughout the five games leading up to the Week 10 outing versus the Buccaneers.
While he only had 17 rushing yards against Tampa Bay, he demonstrated his versatility by amassing 55 yards off a career-high six receptions. The Raiders haven't done much of anything right in 2022-23, so DFS participants need to look in Walker's direction.
Jeff Wilson Jr. - vs. HOU ($7,700)
Wilson made his Dolphins debut in the Week 9 meeting with the Chicago Bears, ending with 51 yards off nine carries. However, he shined in the win over the Browns heading into the bye, recording 119 yards off 17 carries for a potent 7.0 YPC.
He also scored a touchdown in that one. Wilson has a fantastic outlook with the Texans on tap, a team that has been atrocious against the run all year. His ceiling will increase even more if Raheem Mostert (knee) can't suit up.
Isiah Pacheco - vs. LAR ($6,300)
Clyde Edwards-Helaire has a high-ankle sprain, and an injury like that is never good. As a result, CEH landed on injured reserve and won't be on the field for a while. Pacheco, who has now combined for 31 touches over the last two games, was already working toward a more prominent role.
Yet, his path to production is much clearer without the possibility of Edwards-Helaire being involved. Granted, Jerick McKinnon remains in the mix, but the rookie should be the featured option out of the backfield in Week 12 against the Rams. Either way, both McKinnon and Pacheco have upsides that can't be ignored.
Also Consider: Austin Ekeler ($8,800), Josh Jacobs ($8,700), Samaje Perine ($6,600)
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FanDuel Wide Receivers - Week 12 DFS Lineup Picks
Tyreek Hill - vs. HOU ($9,200)
Hill has (arguably) been the league's top wide receiver throughout the 2022-23 campaign. He leads the league in several areas, including in catches (81) and receiving yards (1,148).
He also trails Justin Jefferson for the most receptions of at least 20 yards or more. Vegas has the Dolphins as the highest-scoring team on the slate, so Hill should remain involved against a horrid Texans' defense.
DeAndre Hopkins - vs. LAC ($8,400)
Hopkins has looked good since returning from suspension. Kyler Murray has missed the last two games due to a hamstring issue. That said, it hasn't stopped Hopkins from being a pivotal piece of the offense.
The wideout has at least nine catches in four of his five appearances in 2022-23 while totaling 53 targets during that span. With Marquise Brown and Zach Ertz sidelined due to injury, Hopkins should continue to produce on the fantasy end.
Also Consider: Jaylen Waddle ($8,100), Terry McLaurin ($7,500), Keenan Allen ($7,300), Chris Godwin ($7,000), Joshua Palmer ($6,800)
FanDuel Tight Ends - Week 12 DFS Lineup Picks
Travis Kelce - vs. LAR ($8,200)
At only $8,200, there's no way Kelce shouldn't be in every DFS lineup. The 33-year-old hasn't had fewer than seven targets in any game this season, with Patrick Mahomes looking in his direction 34 times over the last three games
Kelce is coming off a three-touchdown performance in Week 11 against the Chargers. He has a fantastic chance to keep producing against that other L.A. team in Week 12.
Tyler Higbee - @ KC ($5,700)
The Rams continue to search for answers offensively, especially now that Cooper Kupp won't be on the field for the foreseeable future. That leaves Allen Robinson II as the official No. 1 receiving option on the depth chart.
Yet, Higbee could be Matthew Stafford's top targets down the stretch. Higbee had a team-high eight targets in the Week 11 loss to New Orleans. While he finished with only 45 yards, he'll clearly play a pivotal role moving forward. Higbee is dealing with a knee injury. But if the veteran can go, he deserves some DFS consideration.
Also Consider: Mark Andrews ($7,300)
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