X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Daily Stats & Leaders
All Pitcher Matchups
Compare Any Players
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

FanDuel MLB DFS Lineup Picks (4/21/21): Daily Fantasy Baseball Advice

Mike Marteny highlights the top FanDuel MLB DFS lineup picks for 4/21/21, and a couple of sleepers to consider while building daily rosters.

It's getaway day in MLB, so only six games permeate the main night slate. Only one pitcher tips the five-figure scale. Can we get away with a fade here? Are there enough other options to gain an advantage by using a cheaper pitcher? We'll get into that.

Rain could affect the start time of the Yankees game, but they should be able to get the game in after an initial delay. The only thing to worry about would be if they can't keep the field in good shape when it rains throughout the afternoon. I do expect it to play and the wind should be blowing heavily out to right. Use pitching at your own risk in that one. They are going to have problems getting the Boston game in. It's possible that the rain will miss Boston, but right now it doesn't look promising.

I'll be providing you with my daily fantasy baseball lineup picks for the FanDuel main slate on 4/21/2021. Be sure to also check out all the MLB player news, including late scratches, and the projected and confirmed daily MLB lineups for each DFS slate. You can also check out today's DraftKings MLB DFS lineup picks, and read more DFS advice and lineup picks for other sports too. Let's get to it!

 

FanDuel DFS Pitchers

Cash Game/GPP Anchor Play:

Aaron Civale – CWS at CLE($10,200)

Civale beat the White Sox just five days ago, but he only picked up four strikeouts. The lack of strikeout potential is a bit of a ding on him, but he is 3-0 with a 2.18 ERA so far this year. Civale hasn't gone less than six innings in any start this year. That alone gives him the highest floor on this slate. Civale isn't a high strikeout guy so I can get on board with a fade here. The big issue is that there aren't many good secondary options.

Potential Alternate Play

Tyler Mahle – CIN vs. ARI($8,800)   

The issue with Mahle over the course of his career has been his ability to get through the order a second time. He simply doesn't go deep into games. Over the course of 64 career starts, Mahle averages just a shade over five innings per start. That's not much time to accumulate points. This season has been much of the same with Mahle only pitching 14 innings across three starts. It has nothing to do with his effectiveness because in the start in which he only lasted four innings, Mahle did not give up a run. That was against tonight's opponent, Arizona. Mahle still picked up 30 FanDuel points in that game. The thing that has me leaning towards Mahle is the 22 strikeouts in 14 innings. That's something I can work with.

 

Want more MLB DFS tools and content? Our MLB Premium package includes our daily DFS Cheat Sheets, Research Station, Optimizer, and access to our Premium Slack Chatrooms where members can chat with our MLB analysts. Check out this recent big win from RotoBaller's RealTalkRaph on DraftKings - join in on the winning!

 

FanDuel DFS Infielders

Joey Votto – 1B, CIN vs. AZ ($2,800)

It has been a rough start for Merrill Kelly again this year. A small ballpark with the wind blowing out wont help him either. Votto has only been shut out in one game this season and just got done with a series in which he destroyed Cleveland pitching. The Arizona staff and bullpen is significantly worse. Votto makes a lot of hard contact against the fastball and changeup that Kelly throws, which comprises almost 70% of his pitches to lefties. He should be able to stay hot here.

Ozzie Albies – 2B, ATL at NYY ($3,000)

Corey Kluber has really struggled this year and this is a terrible matchup for him anyway. Kluber's fastball velocity is down a bit which could explain the struggles. Still, this is not a team you want to struggle against. I'm not going hard after Kluber since the Yankees bullpen has one again been a strength. Albies profiles well and is reasonably priced.

Jose Ramirez – 3B, CLE vs. CWS ($3,300)

This feels cheap for Ramirez, especially when you consider that the White Sox basically turning this into a bullpen game. Ramirez started slowly, but he has 78.4 FanDuel points over the last five games. I'm not scared of Jonathan Stiever or the White Sox bullpen. Stiever struggled in his cup of coffee in 2020 and he didn't have a strong spring either. ATTACK!

Javier Baez – SS, CHC vs. NYM ($3,800)

Kris Bryant has been the talk of the Cubs this year and for good reason. However, he doesn't profile nearly as well as Baez does. Baez absolutely destroys sliders with a 72.7% hard contact rate. The only thing he doesn't profile well against is changeups. All eight home runs that David Peterson has allowed in his career have been given up to righties. If anyone is hitting one in Wrigley tonight, the metrics strongly suggest that it will be Baez.

 

FanDuel DFS Outfielders

Jesse Winker – OF, CIN vs. AZ ($3,700)

Winker is leading off a potent offense against a pitcher that has given up a run per inning so far this year in a small ballpark with the wind blowing out. The Arizona bullpen has been one of the better units so far this year, but I'm banking on the Reds putting up some big numbers against Kelly before they knock him out of the game.

Franmil Reyes – OF, CLE vs. CWS ($3,200)

Reyes has the rawest power of anyone on the team. Reyes made up for his cold series on the Southside last week in which he went 0-13 by picking up three hits and a walk in the first game of the series in Cleveland. We don't really know who or what the White Sox are going to throw at Cleveland tonight. We only know that Jonathan Stievers will be part of it. That's good enough for me knowing he has a bullpen with an ERA on the wrong side of 4 backing him up.

Jorge Soler – OF, KC vs. TB($2,600)

Soler is quite familiar with Michael Wacha. He started his career with the Cubs when Wacha was with the Cardinals. Then Soler moved to Kansas City where they play the Cardinals in the I-70 series every year. Wacha is 5-12 with three homers, seven runs, and seven RBI in his career against Wacha. BvP worked for those of us last night who threw a struggling Mitch Moreland out there against Matt Shoemaker. This could work for a struggling Soler as well.

 

FanDuel DFS Stacks Options

  • Cincinnati Reds
  • Kansas City Royals
  • Cleveland Indians
  • Chicago Cubs right-handers



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy baseball app for iPhone and Android with 24x7 player news, injury alerts, sleepers, prospects & more. All free!




MLB DFS News and Injury Alerts


More DFS Lineup Picks and Analysis




POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Daily Stats & Leaders
All Pitcher Matchups
Compare Any Players
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

REAL-TIME FANTASY NEWS

T.J. Sanders

Bills Sign T.J. Sanders to Rookie Deal
Christian Wilkins

Raiders Put Christian Wilkins on PUP List
Jabari Small

Lions Add Jabari Small to Backfield
Quinshon Judkins

Remains Unsigned, Won't Report With Rest of Rookies
Mason Taylor

Agrees to Rookie Contract with Jets
Hendon Hooker

Leading Lions QB2 Battle Entering Training Camp
Ozzy Trapilo

Agrees to Rookie Contract with Bears
Tate Ratledge

Agrees to Rookie Contract with Lions
Jack Bech

Signs Rookie Contract with Raiders
Yegor Chinakhov

Requests Trade
Dakota Joshua

Maple Leafs Acquire Dakota Joshua
Lukas Dostal

Signs Five-Year Extension with Ducks
Shemar Stewart

Not Practicing With College Team
Uchenna Nwosu

Seahawks Place Uchenna Nwosu on PUP List
Taylor Decker

Alim McNeill, Taylor Decker Placed on PUP List
Tyrion Davis-Price

Titans Waive Tyrion Davis-Price
Tre Harris

Chargers Relying on Tre Harris to Be Starting X Receiver
Eugenio Suárez

Eugenio Suarez Expected Back Friday
Micah Parsons

Will Become Highest-Paid Non-QB
MarShawn Lloyd

Vying for RB2 Role
Keandre Lambert-Smith

KeAndre Lambert-Smith Finds End Zone in First Training Camp Practice
Tyler Shough

Pushing for Fully Guaranteed Rookie Deal
Ar'Darius Washington

Goes on PUP List
Lamar Jackson

to be Even Better in 2025?
Tre Harris

Agrees to Terms on Rookie Deal
Damian Lillard

Returning to Portland
Paul Skenes

Pirates Could Preserve Paul Skenes in Second Half
Brooks Barnhizer

Grabs 19 Points, Nine Boards in Summer League Win
Jeremiah Fears

Scores 22 Points in Summer League Loss to Thunder
Isaiah Collier

Collects 17 Points In Summer League Win
Caleb Houstan

Joins Hawks
AJ Johnson

Erupts for 25 Points in Summer League Loss
Washington Wizards

Leaky Black Logs Double-Double in Loss to Jazz
Connor Norby

Undergoes Surgery, Expected to Miss 6-8 Weeks
Trey Alexander

Tallies 25 Points in Losing Effort
Johni Broome

Records Second Consecutive Double-Double
Jahmir Young

Has Historic Summer League Outing
Rob Dillingham

Plays Big Role in Wednesday's Win
Tyrese Proctor

Erupts for 35 Points Against Kings
Cody Williams

Leads Jazz to Victory Against Wizards
LeBron James

Mavs Not Interested in "Gutting its Roster" For LeBron James
Josh Hart

Undergoes a Procedure on Right Finger
Jake Burger

Goes on 10-Day Injured List With Quad Strain
Sal Frelick

Dealing With Grade 1 Hamstring Strain, TBD for Start of Second Half
Chris Sale

Plays Catch
Los Angeles Clippers

Bradley Beal Heading to Los Angeles to Join Clippers After Contract Buyout
Rayan Rupert

Scores 24 Points in Summer League Win
Derik Queen

Collects Third Consecutive Double-Double in Summer League Loss
GG Jackson II

Records 13 Points in Summer League Action on Tuesday
Johni Broome

Logs Double-Double Against Wizards
DaRon Holmes II

Records Double-Double in Summer League Loss to Raptors
Kyle Schwarber

Named All-Star Game MVP
Harris English

Takes Stellar 2025 Performance to The Open Championship
Aldrich Potgieter

Seeks Better Result in Northern Ireland
Cameron Young

Likely to Hang Around at The Open Championship
Cameron Smith

Just Trying to Make the Cut at Royal Portrush
Jordan Spieth

Is Jordan Spieth Still a Natural for Links Style Golf?
Patrick Reed

a Viable Option at The Open Championship
PGA

Sungjae Im Wants to Rebound from Last Experience at Royal Portrush
Xander Schauffele

Looks to Defend His Claret Jug at Royal Portrush
Tony Finau

Trying to Turn Tide at Royal Portrush
Daniel Brown

Seeks a Rebound at The Open Championship
Rory McIlroy

Will be the Most Watched Player This Week at Royal Portrush
Daniel Berger

Trending Poorly as The Open Championship Looms
Clayton Kershaw

Retires Both Batters In ASG Appearance
Eugenio Suárez

Eugenio Suarez Hit In Pinky In All-Star Game, X-Rays Negative
MLB

NL All-Stars Win On Tie-Breaker Home Run Swing-Off
Robert MacIntyre

Hoping to Bounce Back at Open Championship
Shane Lowry

Hopes to Repeat at Royal Portrush
Brian Harman

Hopes to Rekindle Some Magic at the 153rd Open
UTA

Michael Carcone Returns to Utah on One-Year Contract
Bowen Byram

Signs Two-Year Deal with Sabres
Morgan Barron

Jets Re-Sign Morgan Barron for Two Years
PGA

Chris Gotterup Punches Ticket to Royal Portrush With Win at Scottish Open
Bryson DeChambeau

Hopes to Reverse Links Golf Struggle at the 153rd Open
Keegan Bradley

Needs to Find The Weekend at Royal Portrush for Ryder Cup Hopes
Oneil Cruz

Ties Home Run Derby Distance Record
Cal Raleigh

Wins 2025 Home Run Derby
Justin Thomas

Finishes Tied For 22nd at Genesis Scottish Open
Scottie Scheffler

Finishes Tied For Eighth at Genesis Scottish Open
Jon Rahm

Finishes in Second at LIV Andalucia
Tallison Teixeira

Suffers First-Round TKO
Derrick Lewis

Scores First-Round TKO
Michael Lorenzen

Royals Put Michael Lorenzen on Injured List With Oblique Strain
Stephen Thompson

Loses Controversial Split Decision
Gabriel Bonfim

Wins Controversial Split Decision
Calvin Kattar

Gets Outclassed At UFC Nashville
Steve Garcia

Extends His Win Streak
Nate Landwehr

Gets Knocked Out
Morgan Charrière

Morgan Charriere Scores Third-Round Knockout
Austen Lane

Suffers Submission Loss
Vitor Petrino

Scores First-Round Submission In Heavyweight Debut
Tuco Tokkos

Earns His First UFC Win
Junior Tafa

Unsuccessful in his Light-Heavyweight Debut
Chase Elliott

Charges to A Finish of Third At Sonoma
Chase Briscoe

Finishes Second With his First Career Road-Course Top-Five at Sonoma
Christopher Bell

Rollercoaster Day Ends With Top-5 Finish at Sonoma
William Byron

Maintains the Regular-Season Points Lead
Kyle Busch

Earns A Hard-Fought Top-10 Finish At Sonoma
Alex Ovechkin

Not Thinking About Retirement
PIT

Penguins Acquire Arturs Silovs
NHL

Nikolai Kovalenko Returns to Russia
Yoshinobu Yamamoto

Tosses Gem Against Giants
Shota Imanaga

Shuts Down Yankees on Sunday
Nathan Eovaldi

Dominant Again in Seventh Win
Tyler Reddick

Evades Near Upset to Remain Alive in In-Season Challenge
Ty Gibbs

One of Three Tylers to Make In-Season Challenge Semifinals
Kyle Larson

Curiously Mediocre at Sonoma Before Late-Race Crash
NASCAR

John H. Nemechek Edges Out Teammate to Make In-Season Challenge Semifinal
Alex Bowman

Ty Dillon Bumps Alex Bowman to Advance to In-Season Challenge Semifinal
Chicago White Sox

Billy Carlson Goes 10th Overall to White Sox
Cincinnati Reds

Steele Hall Selected Ninth by Cincinnati
Toronto Blue Jays

Blue Jays Select JoJo Parker with Eighth Overall Pick
Miami Marlins

Marlins Select Aiva Arquette With Seventh Overall Pick
Pittsburgh Pirates

Pirates Select Seth Hernandez with Sixth Overall Pick
Shane Van Gisbergen

Can Anyone Beat Shane van Gisbergen at Sonoma?
Tyler Reddick

Better at Sonoma Than Record Shows
Chase Elliott

a Prime DFS Option at Sonoma
Michael McDowell

Struggling a Bit at Sonoma
NASCAR

Christopher Bell Has Never Finished Better Than Ninth at Sonoma
Ryan Blaney

Has Top-10 Upside at Sonoma
NASCAR

Sunday at Sonoma Will Likely Be a Long Race for Bubba Wallace
Kyle Larson

Is A Likely Top-Five Contender for Sonoma
Ryan Preece

Points Position Could Affect Race at Sonoma
Todd Gilliland

Struggling to Find Speed at Sonoma
Ty Gibbs

May be an Underrated Favorite to Compete for the Win at Sonoma
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF