X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

#1 Expert Projections
Save 30% Now
Import Your Leagues
Top-Rated Accuracy
Draft Simulator
Enter League Settings
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

DraftKings, FanDuel Daily Fantasy Baseball Picks (9/17/22): Today's Top MLB DFS Lineups

Yordan Alvarez - Fantasy Baseball Rankings, Draft Sleepers, MLB Injury News

The top daily fantasy baseball lineup picks for FanDuel and DraftKings on September 17, 2022. Mike Marteny's MLB DFS analysis and sleepers for building optimal DFS rosters.

Today's MLB slates are split up as is the norm for September baseball. Half the guys I think will play will not, so you have to be as flexible as Gumby to play MLB DFS in September, but that also means that there is a lot of money out there should you dare to dive in those waters. That's why we're here.

There are nine games on the main slate for tonight's action. Two pitchers tip the scales on DraftKings at five figures. Five of them weigh in over that mark on FanDuel. So, hey...at least we have some nice pitching on this slate! That makes it easier.

As always, this article will provide my daily fantasy baseball lineup picks for DraftKings and FanDuel. Saturday's main slate locks at 7:10 pm EST on 9/17/2022. The lineup picks will range from some elite high-priced players to mid-priced options and value plays. I'll give you a few of my top pitching options and then some infielders, outfielders, and teams to stack! You can also read more DFS advice and lineup picks for other sports here. It's also essential to monitor injury news and today's MLB starting lineups. Now that we got all of that out of the way, it's onto the picks!

Featured Promo! Save 30% on any Premium Pass using discount code NEW. Win more with our DFS, Betting and Season-Long Pass, get expert tools and advice from proven winners! GAIN ACCESS

 

DraftKings, FanDuel Pitchers - MLB DFS Lineup Picks

Shohei Ohtani vs. SEA ($10,400 DK and FD)

It should come as a surprise to no one that Seattle has not hit Ohtani well. Not this year. Not ever. This year the M's have been even worse against Ohtani though. Ohtani boasts 14 strikeouts with just two runs allowed on ten hits in 12 innings against Seattle. That low WHIP counts for more on DK, but those K ratios play big on both sites. Don't overthink this. In cash, you need Ohtani.

George Kirby at LAA ($8,000 DK, $9,300 FD)

It's counterintuitive to use pitchers against each other on DraftKings, but I'm seriously considering it. Kirby has dominated the Angels this year, striking out 21 Halos in 17.2 innings while allowing six runs. I particularly like the high strikeout numbers and will pivot to Kirby in GPP formats. I prefer the larger savings on DraftKings, but you can't argue with the results. Kirby's ERA is still below 3 on the season.

Also consider: Chris Bassitt, Joe Musgrove, Jose Urquidy

 

Want more MLB DFS tools and content? Our MLB Premium package includes our daily DFS Cheat Sheets, Research Station, Optimizer, and access to our Premium Slack Chatrooms, where members can chat with our MLB analysts. Check out this recent big win from RotoBaller's Jon Anderson on DraftKings - join in on the winning!

DraftKings, FanDuel Infielders - MLB DFS Lineup Picks

Freddie Freeman - 1B, LAD at John Brebbia ($5,600 DK, $4,300 FD)

Brebbia is just the opener, but it's not like it matters. Freeman is running hot right now. Freeman is hitting .395 with four homers, ten RBI, and just five strikeouts to seven walks over the last ten games. Freeman is having a September to remember so far. He should keep it up against the Giants in a bullpen game for them.

Eduardo Escobar - 3B, NYM vs. Bryse Wilson ($4,000 DK, $3,100 FD)

Escobar had a rough August, but he is on a roll of late with five homers already in September to go with a .373 average and nine RBI. Since Austin Riley is in the midst of a God-awful slump, I'll save some pennies and drop down to the red-hot Escobar.

Willy Adames - SS, MIL vs. Jameson Taillon ($5,000 DK, $3,400 FD)

Adames comes at a nice discount on FanDuel, but again, he's running so hot I'll use him anywhere. The former Rays prospect is hitting .351 with three homers and 10 RBI in the last week! Taillon has been had a few times this year. In fact, his last start was the first time since July 28 that he didn't allow a homer. I'll say Adames gets him today.

 

DraftKings, FanDuel Outfielders - MLB DFS Lineup Picks

Yordan Alvarez - OF, HOU vs. Cole Irvin ($6,400 DK, $4,300 FD)

I really love the price drop on Alvarez on FD, but I'll use him anywhere right now. He has double-digit fantasy points in each of the last five games he has played in. He homered in his first three at-bats last night. The odds of him doing that again? Not terrible. Yordan is 8-for-17 with a pair of homers in his career against Irvin. By the way, he is hitting .426 with six homers and 12 RBI against anyone unfortunate enough to wear an A's uniform against him this year.

Ronald Acuna Jr. -OF, ATL vs. Aaron Nola ($5,600 DK, $3,700 FD)

There are a few Braves that hit Nola well. One of them is Austin Riley, who is colder than Antarctica in January right now. The other is Acuna, who is 11-for-32 with three homers and seven walks in his career against Nola. I don't make it a point to go after pitchers like Nola, but I do when it offers leverage. Most will ignore the Braves here, but Acuna gets on base and hasn't struck out much against Nola. That's a good combination.

Aristides Aquino - OF, CIN at Jose Quintana ($2,100 DK, $2,500 FD)

Aquino is too cheap on DraftKings. He is hitting .306 with a pair of homers and four RBI this week. Quintana usually isn't a victim of gopher balls, but Aquino's raw power is among the best in the league. He just can't hit righties. Fortunately for us and our budget, Quintana is a lefty. I'll ride a warm Aquino against a lefty any day.

 

DraftKings, FanDuel MLB DFS Stacks

Here are my top stacks for tonight (in the order in which I like them):

Los Angeles Dodgers - Any time an offense like this goes up against any team's bullpen, they have my attention. The Dodgers are expensive for a reason. Try some Cody Bellinger or Justin Turner for some much-needed salary relief to afford the rest of this stack.

New York Mets - Bryse Wilson has allowed at least three runs in every start for the last six weeks. I already talked about Escobar's hot streak, but Pete Alonso, Jeff McNeil, and Francisco Lindor are also running hot.

Honorable mention: Arizona Diamondbacks

I hope I gave you a head start on your research today and I wish you the best of luck! If you ever have questions about DFS or fantasy baseball, my DMs are always open and I appreciate you taking the time to read my picks today.



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy baseball app for iPhone and Android with 24x7 player news, injury alerts, sleepers, prospects & more. All free!




MLB DFS News and Injury Alerts


More DFS Lineup Picks and Analysis




POPULAR FANTASY TOOLS

#1 Expert Projections
Save 30% Now
Import Your Leagues
Top-Rated Accuracy
Draft Simulator
Enter League Settings
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Khris Middleton

Sits Out Friday's Game
Tre Johnson

Back From Three-Game Absence Friday
Isiah Pacheco

Can Isiah Pacheco Bounce Back in RB2 Role in Detroit?
Jarace Walker

Won't Return Friday
Tristan Vukcevic

Active Friday Night
Tanner Bibee

Day-to-Day, Could Make his Next Start
Alexandre Sarr

Returns to Action Friday
Ausar Thompson

Questionable Against Minnesota
Bilal Coulibaly

Available Against Warriors
Tobias Harris

Listed Questionable Saturday
Stephen Curry

to Sit Out At Least Two More Games
Noah Clowney

Cleared to Return From Four-Game Absence
Jalen Duren

May Sit Saturday
Kyle Filipowski

Available Friday
Rui Hachimura

Available After Two-Game Absence
Tyrese Maxey

Has Chance to Play Saturday
Jahmai Mashack

Remains Out Friday
Jaden McDaniels

Not Playing Saturday
De'Anthony Melton

Won't Play Friday Night
Anthony Edwards

Remains Sidelined Saturday
Rob Dillingham

is Available to Play on Friday
Luka Dončić

Luka Doncic Ready to Rock Friday
Isaac Okoro

to Suit up on Friday
Nnamdi Madubuike

Optimism That Nnamdi Madubuike Will Return From Neck Injury
Dylan Garand

Starts Friday
Noah Ostlund

Won't Play Friday
Connor Zary

Returns to Practice
Samuel Honzek

Won't Return This Season
Damon Severson

Labeled Week-to-Week
Sam Steel

Leaves Road Trip Due to Injury
Mikko Rantanen

Could Return Saturday
NFL

Jordyn Tyson to Hold A Workout for Teams in April
New York Jets

Jets Unlikely to Draft Ty Simpson in the First Round?
Shane Baz

Orioles Agree to Five-Year Extension
Jeremy Peña

Jeremy Pena Making Season Debut on Friday Against Angels
Tiger Woods

Involved In Rollover Car Crash
Bhayshul Tuten

Remains a Clear Breakout Candidate Heading into 2026
NFL

Can Jonah Coleman Develop into a Starting NFL Running Back?
Rico Dowdle

Remains Likely to Split Carries in Pittsburgh
NFL

Can KC Concepcion Be a Dynamic Playmaker in the NFL?
Rashid Shaheed

Is Rashid Shaheed Limited to a Downfield Role in Seattle?
Marcus Mariota

Remains an Injury Away from Playing Time in Washington
Najee Harris

to Meet With Raiders Next Thursday
Damar Hamlin

Bills Re-Sign Safety Damar Hamlin to One-Year Deal
Tanner Bibee

Shoulder Issue Not Considered Serious
NFL

Nicholas Singleton Relying on Traits Over Tape for Early Draft Capital
J.K. Dobbins

Positioned for Another Strong Season in Denver
NFL

Malachi Fields' Draft Stock Looks to Be Sliding
Barrett Hayton

Out Week-to-Week
Travis Etienne Jr.

Should See Feature Role Following Big-Market Deal
Tony DeAngelo

to Miss 1-2 Weeks
Sam Steel

Makes Early Exit Against Islanders
NFL

Ty Simpson Garnering First-Round Buzz
Damon Severson

Exits With Upper-Body Injury Thursday
Joe Pyfer

Set For UFC Seattle Main Event
Yaroslav Askarov

Suffers New Injury Blow
Israel Adesanya

Returns At UFC Seattle
Evan Rodrigues

Breaks Finger Thursday
Maycee Barber

Looks To Extend Her Win Streak To Eight
Sidney Crosby

Suffers Lower-Body Injury Thursday
Alexa Grasso

Looks To Get Back In The Win Column
Dominic Canzone

a Top Pickup After Two-Homer Game
Niko Price

In Dire Need Of Victory
Michael Chiesa

Set For Retirement Fight
Chase DeLauter

Launches Two Home Runs, Emerges as Top Waiver-Wire Target
Lerryan Douglas

Set For His UFC Debut
Julian Erosa

Looks To Bounce Back
Tanner Bibee

Leaves Opening Day Start Early With Shoulder Inflammation
Tyler Allgeier

Joins a Crowded Backfield in Arizona
Kenneth Gainwell

Can Kenneth Gainwell Maintain PPR Prowess in New Digs in Tampa?
Jakub Dobes

Defeats the Blue Jackets on Thursday
NFL

Zachariah Branch a Day 2 Receiver With Game-Changing Speed
Cade Otton

Quietly Due for a Bigger Workload?
Noah Cates

has Two-Point Game on Thursday
Cristopher Sánchez

Cristopher Sanchez Makes a Statement on Opening Day With 10 Strikeouts
Kevin McGonigle

has Four Hits in Impressive MLB Debut
Nico Hoerner

Cubs Agree to Six-Year Deal With Nico Hoerner
Jacob Misiorowski

Shows Off his High-Strikeout Upside in Opening Day Win
Marcus Foligno

Available Against Panthers
Tony DeAngelo

Unavailable Thursday
Anthony Mantha

Good to Go Thursday
Paul Skenes

Greeted Harshly by Mets on Opening Day
Thomas Chabot

Out 4-8 Weeks After Surgery
Robert Thomas

Sits Out Thursday's Action
Brandon Lowe

Hits Two Home Runs on Opening Day
Ketel Marte

Active, Leading Off on Opening Day
Kevin McGonigle

Batting Sixth in MLB Debut
Jeremy Peña

Jeremy Pena Not in the Lineup on Opening Day
JJ Wetherholt

Batting Leadoff in MLB Debut
Jackson Chourio

Placed on Injured List with Fractured Hand
Francisco Lindor

Officially Starting on Opening Day
Rickie Fowler

PGA DFS Expert Roundtable and Survey - 2026 Texas Children's Houston Open (Premium) - RotoBaller Team Picks
Sean Murphy

Lands on 10-Day Injured List
Brooks Koepka

PGA Betting Expert Roundtable: RotoBaller Staff Picks - 2026 Texas Children's Houston Open (Premium)
Bryce Miller

Placed on 15-Day Injured List With Oblique Strain
Brooks Koepka

RotoBaller's One And Done Picks To Consider - Texas Children's Houston Open (Premium Content)
Brooks Koepka

DraftKings Core Four: PGA DFS - 2026 Texas Children's Houston Open (Premium Content)
Dustin Johnson

PGA Course Preview and Betting Picks: 2026 Texas Children's Houston Open
Ryan Fox

a High-Upside Value in Houston
Marco Penge

a Boom-or-Bust Option in Houston
Aaron Rai

Looks to Bounce Back in Houston
Jason Day

a Volatile Option at the Texas Children's Houston Open
Harris English

Eyes a Bounce-Back at the Texas Children's Houston Open
Ben Griffin

Looks for Turnaround at the Texas Children's Houston Open
Rickie Fowler

Brings Strong Form Into Texas Children's Houston Open
Brooks Koepka

Patrick's Picks: Top Betting Plays for 2026 Texas Children's Houston Open (Premium)
Ryan Gerard

Can Continue Rolling at Texas Children's Houston Open
Pierceson Coody

Bounces Back at Valspar Championship
Rasmus Hojgaard

Trying to Get Back on Track at Texas Children's Houston Open
Michael Thorbjornsen

Playing Well Heading to Texas Children's Houston Open
Harry Hall

Looking for Consistency at Texas Children's Houston Open
Brooks Koepka

Continues Building Momentum
Brooks Koepka

PGA Best Bets: Novig Matchup Picks and Finishing Position Props for Texas Children's Houston Open
Lerone Murphy

Suffers His First Loss
Movsar Evloev

Edges Out Lerone Murphy
CFB

Notre Dame Ranks No. 1 in Returning Production for 2026
Michael Aswell

Jr. Drops Decision At UFC London
Michael Aswell

Luke Riley Outclasses Michael Aswell Jr.
Sam Patterson

Suffers Unanimous-Decision Loss
Michael Page

Wins Lackluster Decision
Austen Lane

Suffers First-Round TKO Loss
Iwo Baraniewski

Delivers 28-Second TKO
Tyler Reddick

Overcomes Adversity for Fourth Victory of the Season At Darlington
Brad Keselowski

Falls Short of Darlington Victory Despite Domination
Ryan Blaney

Recovers From Pit-Road Struggles to Score Career-Best Darlington Finish
Carson Hocevar

Rallies to Finish Fourth at Darlington
Kyle Larson

Decent Performance Ends with Technical Issues At Darlington
Tyler Reddick

the Clear Favorite at Darlington
Kyle Larson

a High-Risk, High-Reward Driver at Darlington
Ryan Blaney

Is Getting Better at Darlington
NASCAR

Bubba Wallace Not Slowing Down at Darlington
Chris Buescher

Should be a Top-10 Contender at Darlington
Austin Cindric

a Sleeper at Darlington
Erik Jones

Quickest in Practice at Darlington
Denny Hamlin

Qualifies Ninth for this Week's Cup Race at Darlington
Chase Briscoe

Is One of the Top DFS Options of the Week for Darlington
William Byron

Is William Byron A Playable DFS Option for Darlington Lineups?
Christopher Bell

Could Christopher Bell be Considered A Decent DFS Option for Darlington?
Chase Elliott

Is Chase Elliott Worth Rostering At Darlington This Week For DFS?
Joey Logano

May Not Have the Speed to Warrant A Darlington DFS Lineup Spot
Ross Chastain

Should DFS Players Trust Ross Chastain at Darlington?
Kyle Busch

Could Kyle Busch Be A Worthy DFS Option for Darlington?
Brad Keselowski

May be A Contriarian DFS Tournament Option At Darlington
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF