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DraftKings, FanDuel Daily Fantasy Baseball Picks (9/17/22): Today's Top MLB DFS Lineups

Yordan Alvarez - Fantasy Baseball Rankings, Draft Sleepers, MLB Injury News

The top daily fantasy baseball lineup picks for FanDuel and DraftKings on September 17, 2022. Mike Marteny's MLB DFS analysis and sleepers for building optimal DFS rosters.

Today's MLB slates are split up as is the norm for September baseball. Half the guys I think will play will not, so you have to be as flexible as Gumby to play MLB DFS in September, but that also means that there is a lot of money out there should you dare to dive in those waters. That's why we're here.

There are nine games on the main slate for tonight's action. Two pitchers tip the scales on DraftKings at five figures. Five of them weigh in over that mark on FanDuel. So, hey...at least we have some nice pitching on this slate! That makes it easier.

As always, this article will provide my daily fantasy baseball lineup picks for DraftKings and FanDuel. Saturday's main slate locks at 7:10 pm EST on 9/17/2022. The lineup picks will range from some elite high-priced players to mid-priced options and value plays. I'll give you a few of my top pitching options and then some infielders, outfielders, and teams to stack! You can also read more DFS advice and lineup picks for other sports here. It's also essential to monitor injury news and today's MLB starting lineups. Now that we got all of that out of the way, it's onto the picks!

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DraftKings, FanDuel Pitchers - MLB DFS Lineup Picks

Shohei Ohtani vs. SEA ($10,400 DK and FD)

It should come as a surprise to no one that Seattle has not hit Ohtani well. Not this year. Not ever. This year the M's have been even worse against Ohtani though. Ohtani boasts 14 strikeouts with just two runs allowed on ten hits in 12 innings against Seattle. That low WHIP counts for more on DK, but those K ratios play big on both sites. Don't overthink this. In cash, you need Ohtani.

George Kirby at LAA ($8,000 DK, $9,300 FD)

It's counterintuitive to use pitchers against each other on DraftKings, but I'm seriously considering it. Kirby has dominated the Angels this year, striking out 21 Halos in 17.2 innings while allowing six runs. I particularly like the high strikeout numbers and will pivot to Kirby in GPP formats. I prefer the larger savings on DraftKings, but you can't argue with the results. Kirby's ERA is still below 3 on the season.

Also consider: Chris Bassitt, Joe Musgrove, Jose Urquidy

 

Want more MLB DFS tools and content? Our MLB Premium package includes our daily DFS Cheat Sheets, Research Station, Optimizer, and access to our Premium Slack Chatrooms, where members can chat with our MLB analysts. Check out this recent big win from RotoBaller's Jon Anderson on DraftKings - join in on the winning!

DraftKings, FanDuel Infielders - MLB DFS Lineup Picks

Freddie Freeman - 1B, LAD at John Brebbia ($5,600 DK, $4,300 FD)

Brebbia is just the opener, but it's not like it matters. Freeman is running hot right now. Freeman is hitting .395 with four homers, ten RBI, and just five strikeouts to seven walks over the last ten games. Freeman is having a September to remember so far. He should keep it up against the Giants in a bullpen game for them.

Eduardo Escobar - 3B, NYM vs. Bryse Wilson ($4,000 DK, $3,100 FD)

Escobar had a rough August, but he is on a roll of late with five homers already in September to go with a .373 average and nine RBI. Since Austin Riley is in the midst of a God-awful slump, I'll save some pennies and drop down to the red-hot Escobar.

Willy Adames - SS, MIL vs. Jameson Taillon ($5,000 DK, $3,400 FD)

Adames comes at a nice discount on FanDuel, but again, he's running so hot I'll use him anywhere. The former Rays prospect is hitting .351 with three homers and 10 RBI in the last week! Taillon has been had a few times this year. In fact, his last start was the first time since July 28 that he didn't allow a homer. I'll say Adames gets him today.

 

DraftKings, FanDuel Outfielders - MLB DFS Lineup Picks

Yordan Alvarez - OF, HOU vs. Cole Irvin ($6,400 DK, $4,300 FD)

I really love the price drop on Alvarez on FD, but I'll use him anywhere right now. He has double-digit fantasy points in each of the last five games he has played in. He homered in his first three at-bats last night. The odds of him doing that again? Not terrible. Yordan is 8-for-17 with a pair of homers in his career against Irvin. By the way, he is hitting .426 with six homers and 12 RBI against anyone unfortunate enough to wear an A's uniform against him this year.

Ronald Acuna Jr. -OF, ATL vs. Aaron Nola ($5,600 DK, $3,700 FD)

There are a few Braves that hit Nola well. One of them is Austin Riley, who is colder than Antarctica in January right now. The other is Acuna, who is 11-for-32 with three homers and seven walks in his career against Nola. I don't make it a point to go after pitchers like Nola, but I do when it offers leverage. Most will ignore the Braves here, but Acuna gets on base and hasn't struck out much against Nola. That's a good combination.

Aristides Aquino - OF, CIN at Jose Quintana ($2,100 DK, $2,500 FD)

Aquino is too cheap on DraftKings. He is hitting .306 with a pair of homers and four RBI this week. Quintana usually isn't a victim of gopher balls, but Aquino's raw power is among the best in the league. He just can't hit righties. Fortunately for us and our budget, Quintana is a lefty. I'll ride a warm Aquino against a lefty any day.

 

DraftKings, FanDuel MLB DFS Stacks

Here are my top stacks for tonight (in the order in which I like them):

Los Angeles Dodgers - Any time an offense like this goes up against any team's bullpen, they have my attention. The Dodgers are expensive for a reason. Try some Cody Bellinger or Justin Turner for some much-needed salary relief to afford the rest of this stack.

New York Mets - Bryse Wilson has allowed at least three runs in every start for the last six weeks. I already talked about Escobar's hot streak, but Pete Alonso, Jeff McNeil, and Francisco Lindor are also running hot.

Honorable mention: Arizona Diamondbacks

I hope I gave you a head start on your research today and I wish you the best of luck! If you ever have questions about DFS or fantasy baseball, my DMs are always open and I appreciate you taking the time to read my picks today.



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REAL-TIME FANTASY NEWS

Kyle Schwarber

has Historic Performance in Rout of Braves
Boston Red Sox

Payton Tolle Expected to Make Debut on Friday
Green Bay Packers

Packers Acquire Micah Parsons, Sign him to Four-Year Extension
Jauan Jennings

Remains Sidelined at Practice
Corey Seager

Undergoing Appendectomy on Thursday
Chris Godwin

to Miss First Month of Season, Possibly More
Quinshon Judkins

Not Considering Return to College
A.J. Brown

Returns to Practice, Expected to Play in Week 1
Jaylen Wright

Undergoes Surgery, Could be Back "Septemberish"
Tyreek Hill

on Track to Play in Week 1
Kyren Williams

to See Reduced Workload?
Jayden Reed

Dealing with Jones Fracture in Left Foot
Lauri Markkanen

Torches Sweden
Neemias Queta

Dominates in EuroBasket Opener
Kawhi Leonard

Clippers Not Allowing Kawhi Leonard to Play Back-to-Backs
Olivier-Maxence Prosper

Mavericks Looking to Trade Olivier-Maxence Prosper
Tyrese Haliburton

Expects to Return in 15 Months
Malik Nabers

Expected to be Full-Go for Week 1
Freddie Freeman

Out Wednesday With Neck Stinger
Alejandro Kirk

Avoids Major Injury, Remains Out on Wednesday
Travis Hunter

Back at Practice, Will be Ready for Week 1
Luis Robert Jr.

Could Miss the Rest of the Season
De'Von Achane

Not Practicing on Wednesday
Trevor Megill

Brewers Place Trevor Megill on Injured List With Flexor Strain
Luis Robert Jr.

Placed on Injured List With Hamstring Strain
Rashee Rice

Accepting Six-Game Suspension to Begin the Year
Kyle Hamilton

Ravens, Kyle Hamilton Finalizing Four-Year Extension
Rashee Rice

NFL Aiming to Place Six-Game Suspension on Rashee Rice
De'Von Achane

Dolphins GM Says De'Von Achane Will be Ready for Week 1
Joe Mixon

Texans GM: "We'll See" if Joe Mixon Plays in 2025
Adam Thielen

Traded to the Vikings
Nick Lodolo

Expected to Return Wednesday Against the Dodgers
Terance Mann

Confident About Having a Big Year in Brooklyn
Zaccharie Risacher

Aims to Improve Ball-Handling Skills
NBA

Pistons And Timberwolves Join Race for Malik Beasley
John Tonje

Signs Two-Way Deal With Jazz
Max Strus

to Miss 3-4 Months After Surgery
Blake Snell

Activated From Paternity List Tuesday
Dallas Cowboys

Cowboys Still Expect Micah Parsons to Play in Week 1
Luis Robert Jr.

Exits Early With Hamstring Soreness
Chris Godwin

Passes Physical, Will be Activated From PUP List
Willson Contreras

Issued Six-Game Suspension
Randy Rodríguez

Randy Rodriguez Placed on Injured List
Brandon Aiyuk

49ers Officially Place Brandon Aiyuk on PUP List
Nathan Eovaldi

Likely Done for the Season
Yordan Alvarez

Activated and Starting on Tuesday
Oneil Cruz

Back From Injured List
New York Mets

Jonah Tong Promoted to Major Leagues
Nikola Jović

Heat Have High Hopes for Nikola Jovic
Golden State Warriors

Cody Martin Drawing Interest From Warriors
Minnesota Timberwolves

Timberwolves Interested in Reunion With Bones Hyland
Kylor Kelley

Joins Lakers
Colin Castleton

Links Up With Magic
Malik Monk

Kings "Not Actively Engaged" in Trade Discussions Involving Malik Monk
P.J. Washington

Mavs Likely to Offer P.J. Washington a Contract Extension
NHL

Jan Rutta Lands in Switzerland
Kirby Dach

Skates on Monday
COL

Tyson Barrie Retires From NHL
Vladimir Guerrero Jr.

Back in Toronto's Lineup
Zhang Mingyang

Suffers His First UFC Loss
Johnny Walker

Gets Back In The Win Column
Brian Ortega

Loses Back-To-Back Fights
Aljamain Sterling

Proves Too Much For Brian Ortega
Chris Sale

Penciled in to Start on Saturday
Waldo Cortes-Acosta

Suffers Unanimous-Decision Loss
Sergei Pavlovich

Wins Decision At UFC Shanghai
Kevin Borjas

Drops Decision At UFC Shanghai
Sumudaerji

Wins Back-To-Back Fights
Kiefer Crosbie

Still Winless In The UFC
Taiyilake Nueraji

Gets His First UFC Win
Ryan Blaney

Earns his Second Daytona Cup Series Win
Tyler Reddick

Locks Into the 2025 Playoffs Despite Underwhelming Daytona Performance
Erik Jones

Misses the 2025 Playoffs Despite Top-Five Run at Daytona
Justin Haley

Best Performance of 2025 Falls Short of Victory at Daytona
Chase Burns

To Throw Bullpen on Tuesday
Kyle Larson

Enters Playoffs As Co-Points Leader
Alex Bowman

Advances to Playoffs Despite Crashing at Daytona
Cole Custer

Finally Shows Signs of Life at Daytona
Daniel Suarez

Lame-Duck Daniel Suarez Delivers Clutch Second-Place Finish
Logan Gilbert

Punches Out 13 in Victory
Chase Elliott

Despite Being Winless at Daytona, Chase Elliott is Probably the Best DFS Option
Ryan Blaney

Will Likely Lead a Lot at Daytona
Kyle Larson

a Poor DFS Option at Daytona
Christopher Bell

Consistent Enough to Consider for DFS
Chris Buescher

Now Must Win His Way Into Playoffs
Ryan Preece

Being One of the Slowest-Starting Fords Makes Ryan Preece a Strong DFS Option
Ross Chastain

Leads a Lot on Drafting Tracks
Daniel Suarez

Now in Desperation Mode With his Career on the Line
Chase Briscoe

Tendency to Finish Better Than He Runs May Reap Dividends at Daytona
Carson Hocevar

Hard to Forecast Since He's Rarely Given 100 Percent at Daytona
Michael McDowell

has a Solid Drafting Record
AJ Allmendinger

A.J. Allmendinger Arguably Starting Too Well for Place-Differential Points
Austin Dillon

Will Likely Be Too Conservative for DFS Consideration
Moses Moody

Warriors Not Interested in Trading Moses Moody
Kevin Durant

Rockets Expected to Agree on New Contract
Trey Murphy III

Warriors, Spurs Interested in Trey Murphy III
CAR

Luke Kunin Joins Panthers on One-Year Deal
Auston Matthews

Says His Health is "Good" Before Start of Season
Roope Hintz

"Feeling Good" Ahead of New Season
Matthew Tkachuk

Recovering From Surgery
Marco Rossi

Wild Re-Sign Marco Rossi to Three-Year Deal

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP