X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


DraftKings, FanDuel Daily Fantasy Baseball Picks (4/25/22): Today's Top MLB DFS Lineups

The top daily fantasy baseball lineup picks for FanDuel and DraftKings on April 25th, 2022. Euan Leith's MLB DFS analysis and sleepers for building optimal DFS rosters.

Happy Monday, RotoBballers! We've got a bit of a mixed bag on our hands tonight. DraftKings has their main slate sitting at seven games, with the featured contest starting at 6:10 pm Eastern, with San Francisco continuing their road trip to meet Milwaukee. Meanwhile, FanDuel has several options on the board, but their main contest only has five games on the schedule starting at 7:07 pm Eastern as Boston visits Toronto.

Monday's weather watch isn't too scary. Some reports of 10-plus mile per hour winds in Philadelphia and St. Louis could help some balls leave the yard, but it's nothing that powerful. Meanwhile, with only 14 pitchers on DraftKings and 10 on FanDuel, finding the right combination will be more critical than ever. Corbin Burnes, Shane Bieber, Max Scherzer, and Walker Buehler deserve a look, but getting two of them on DraftKings is tricky.

This article will provide my daily fantasy baseball lineup picks for FanDuel and DraftKings on the 4/25/2022 Main Slate. You can also read more DFS advice and lineup picks for other sports. It's also essential to monitor injury news and today's MLB starting lineups. If you have any questions or comments, find me on Twitter @EuanOrYouOut and send a tweet my way!

Featured Promo! Save 50% on any PGA Premium Pass using discount code MASTERS, this week only! Win more with our DFS and Betting Packages, get expert tools and advice from proven winners including the Lineup Optimizer, Research Station, betting/props cheat sheet and more. GAIN FULL ACCESS HERE

 

DraftKings, FanDuel Pitchers - MLB DFS Lineup Picks

Corbin Burnes - P, MIL vs. SF ($10,200) - DraftKings only

Because FanDuel only has a five-game slate for their featured contest, we can only play Corbin Burnes on DraftKings. After a rocky start on Opening Day, the reigning NL Cy Young winner has bounced back with two electric outings against Baltimore and Pittsburgh. Across 14 innings, Burnes collected 18 strikeouts and gave up two runs while producing an elite 16.7 percent swinging-strike rate and averaging 31.1 DK PPG. While the Giants will pose a much tougher test, their 24 percent strikeout rate to righties keeps Burnes in the discussion as a must-have pitching option on the seven-game schedule.

Walker Buehler - P, LAD at ARI ($8,800 DK; $9,400 FD)

Every time a stock crashes, it feels like someone is yelling, "Buy the dip!" Well, that's exactly what we're doing with Walker Buehler and his matchup with Arizona. Unfortunately, the young righty isn't firing on all cylinders to kick off 2022 as he's rocking a 4.02 ERA, 1.47 WHIP, and not-s0-good-looking 16.2 percent strikeout rate. However, diving deeper into his profile shows he may just be suffering from a bit of bad luck.

The .306 BABIP he's currently saddled with would be a career-high for an entire season, and his called-strike percentage (14.5%) would be a career-low by more than three percent. Buehler will be fine when those numbers begin to regress to his career average, and fantasy managers, DFS and season-long, will calm down about the 2022 Cy Young finalist. A date with the free-swinging Diamondbacks (27.7 percent strikeout rate) offers a fantastic antidote to the right-handed hurler's early-season pains.

Others to consider (DraftKings): Max Scherzer at STL ($9,300), Framber Valdez at TEX ($8,400), Kyle Gibson vs. COL ($6,800), Jose Berrios vs. BOS ($5,500)

Others to consider (FanDuel): Michael Lorenzen vs. CLE ($7,400), Dane Dunning vs. HOU ($7,000)

 

Want more MLB DFS tools and content? Our MLB Premium package includes our daily DFS Cheat Sheets, Research Station, Optimizer, and access to our Premium Slack Chatrooms, where members can chat with our MLB analysts. Check out this recent big win from RotoBaller's RealTalkRaph on DraftKings - join in on the winning!

 

DraftKings, FanDuel Infielders - MLB DFS Lineup Picks

Rhys Hoskins - 1B, PHI vs. Kyle Freeland ($5,100) - DraftKings only

It's a shame this game isn't on DK, but I'll stack against Freeland where I can. Hoskin's on-base skills give him a concrete floor to build upon, which we can work with on a seven-game schedule. Another thing giving me confidence is Phillies manager Joe Girardi continuing to pencil Hoskins in as the second man in his batting lineup this season despite only one home run on the year and two hits in the last five games.

Jeff McNeil - 2B/OF, NYM vs. Miles Mikolas ($3,700 DK; $3,200 FD)

I'm not sure what Jeff McNeil did to deserve being moved down the Mets order, but he's still producing as the eighth hitter, and it keeps him in my DFS thoughts. This year, the utility bat is seen as an auto sit versus lefties, but that won't matter with Miles Mikolas on the mound for St. Louis. Over his previous three games, McNeil is 4-for-12 with four runs, two extra-base hits, and an RBI. If you're struggling for salary relief in your lineups, he's a great floor play.

Rafael Devers - 3B, BOS at Jose Berrios ($4,500 DK; $4,000 FD)

I posed the question in the RotoBaller DFS chat about why Jose Berrios was only $5,500 on DraftKings, and Mark Kieffer (our Sunday DFS picks writer) responded with:

So shoutout to Mark for pointing this out. If Berrios is extremely chalky, a Boston stack is a perfect pivot. Devers' price tag seems to be unfairly discounted due to a .614 OPS over his last 10 games. However, for the season, the 2021 All-Star is still performing in the advanced stats:

Rafael Devers: 2021 Statcast
Category Number Percentile
xBA 0.304 84%
xSLG 0.558 85%
xwOBA 0.366 70%
Barrel % 11.1 72%

The numbers aren't what we usually expect from Devers, but they are still serviceable in DFS. I'm not worried about Raffy Devers, and neither should you be. Take this discount and run for the hills as you build a contrarian Red Sox stack.

Jeremy Pena - SS, HOU at Dane Dunning ($4,800 DK; $2,900 FD) - Better on FanDuel

Pena did not take kindly to being moved down the order by Dusty Baker on Sunday. The shortstop launched a two-run walk-off homer to dead center to help the Astros avoid a three-game sweep at the hands of Toronto.

The rookie has shown flashes in his first major league season, with four extra-base hits in his last seven games. After a moment like that, it'll be interesting to see his lineup position tonight. Baker can get stuck in his way at times, but Pena has a chance to be special in Houston, and getting him more ABs in important situations is crucial for his development. Dane Dunning's 11.8 percent walk rate this year should give Houston, one of the game's most patient teams, plenty of baserunners in the first game of the 2022 Lone Star Series.

 

DraftKings, FanDuel Outfielders - MLB DFS Lineup Picks

Nick Castellanos - OF, PHI vs. Kyle Freeland ($5,300) - DraftKings only

The other game only on DraftKings this evening is the Phillies-Rockies contest. It's a shame for FD players as they miss out on the chance to stack against Kyle Freeland. However, for DK managers, it's time to reap the rewards. Castellanos has reached base in four straight games and seems to be enjoying life in a Philadelphia jersey. In these last four games, the 2021 Silver Slugger is 7-for-15 with three runs, a double, a home run, and three RBI. He's also averaging a huge 11 DK PPG in that stretch. Rockies southpaw Kyle Freeland and his 7.71 ERA will be in for a rough day against this explosive Phillies lineup.

Michael Brantley - OF, HOU at Dane Dunning ($3,500 DK; $2,600 FD)

Last year, it seemed Michael Brantley couldn't do anything except collect timely base hits. I remember having him in my DFS lineups for days at a time, and he always produced. It feels like he's entering one of those runs right now, and we can still capitalize on a cheaper-than-it-should-be price point. In the weekend series versus Toronto, the left-handed outfielder went 6-for-12 with three runs, a double, and this home run off a fellow lefty in Yusei Kikuchi.

Cody Bellinger - OF, LAD at Merrill Kelly ($3,200 DK; $3,300) - Better on DraftKings

It's not very often you see a hitter cost less on DraftKings than FanDuel. It's even rarer to see a player as "hot" as Cody Bellinger have his salary stay this discounted. While the left-handed slugger became the most polarizing fantasy baseball player of the offseason, it seems like we are getting the "good" version of the 2019 NL MVP right now, and I'm more than okay riding the wave. Over the last 10 games, Belly is slashing .297/.316/.649 with two doubles, a triple, three long balls, and a stolen base.

 

DraftKings, FanDuel MLB DFS Stacks

Philadelphia Phillies vs. Colorado Rockies (Kyle Freeland, LHP)

I've already mentioned Rhys Hoskins and Nick Castellanos against Freeland today, but I wouldn't rule out Bryce Harper or Kyle Schwarber just because it's a lefty on the mound. Of course, there's no way to fit Castellanos, Harper, and Schwarbomb in your lineup tonight, but picking one and making a mini-stack with Alec Bohm ($3,600) is an excellent way to attack this Rockies pitcher.

Texas Rangers vs. Houston Astros (Framber Valdez, LHP) - Sneaky stack

You wouldn't think the Rangers against Framber Valdez would be a place to attack, but Texas is sneaky good against southpaws in 2022. As a squad, they're slashing .282/.345/.494 versus left-handed hurlers, and their 29 RBI and seven home runs put them first and second among the 30 MLB teams. Mitch Garver ($4,300), Marcus Semien ($4,200), and Adolis Garia ($3,400) are cheaper routes to get a couple of Rangers into your lineups.

 



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy baseball app for iPhone and Android with 24x7 player news, injury alerts, sleepers, prospects & more. All free!




MLB DFS News and Injury Alerts


More DFS Lineup Picks and Analysis




REAL-TIME FANTASY NEWS

Victor Wembanyama

Headlines 2025-26 All-Defensive First Team
Ajay Mitchell

Starting Game 3 Against Spurs
Dylan Harper

Available for Game 3 Against Thunder
De'Aaron Fox

Returns to Action Friday
Jalen Williams

Won't Play Friday Night
Derrick Henry

Remains in RB1 Discussion
Ladd McConkey

is Solid Buy-Low Candidate
Ryan Flournoy

an Intriguing Dynasty Stash Option
Jalen Nailor

is Expected to Have Larger Role in Las Vegas
Frederik Andersen

Hurricanes Keep Faith in Frederik Andersen
Devon Levi

Attracting Interest From Senators
Jacoby Brissett

Cardinals Not Close to a Reworked Deal
Scott Wedgewood

Starting Game 2 Against Golden Knights
Ben Hutton

Scratched for Game 2 Against Avalanche
Mark Stone

Won't Play Friday
Jackson Merrill

has Sore Ribs, Expected to Avoid Injured List
Cale Makar

Remains Out Friday
CFB

Jaron-Keawe Sagapolutele Looking to Take Sophomore Leap
CFB

Jadan Baugh Primed to Lead Florida Offense in 2026
CFB

LSU Hires Ed Orgeron As Special Assistant
NFL

Evan Stewart Pushing Oregon Receiving Corps
CFB

North Carolina and South Carolina Cancel Home-And-Home Series
CFB

Confidence High in Mississippi State's Kamario Taylor
MLB

Reds-Cardinals Game Postponed on Friday
New York Giants

Giants, GM Joe Schoen Agree on a Multi-Year Extension
Andrew Thomas

Giants Managing Multiple Injuries for Andrew Thomas
Cam Ward

Loses 10 Pounds in the Offseason
Trevor Story

has Hernia Surgery, Expected to Miss 6-10 Weeks
Roman Anthony

Dealing With Sprained Ligament in his Finger
Tucker Kraft

a Top Trade Target in Dynasty Leagues?
Cedric Tillman

Falling Out of Favor in Cleveland
Emmett Johnson

the Handcuff to Roster in Kansas City?
Devaughn Vele

Could Dynasty Managers Sell High on Devaughn Vele Early in the Season?
Brenen Thompson

a Perfect Fit for Chargers, Rising in Dynasty Leagues?
Jonathan Taylor

Is Jonathan Taylor Still a High-End Dynasty Option?
Malik Nabers

' Recovery Timeline Still Unclear
Jaxon Smith-Njigba

Comfortably Into His Dynasty Prime
Saquon Barkley

Still a Capable League-Winner at a Sunken Dynasty Cost
Jack Campbell

Signs Four-Year Extension with Lions
Matthew Stafford

Signs One-Year Extension with Rams
Evan Mobley

Fills the Box Score in Game 2 Loss
James Harden

Held to Two Assists Thursday
Donovan Mitchell

Leads Cavaliers in Scoring in Game 2 Defeat
Karl-Anthony Towns

Records Double-Double in Game 2 Win
Sebastian Aho

Picks Up an Assist in Series-Opening Loss
Mikal Bridges

Adds 19 Points as Knicks Grab 2-0 Lead
Jalen Brunson

Hands Out 14 Assists in Game 2 Win
Seth Jarvis

Needs 33 Seconds to Score in Game 1 Loss
Josh Hart

Erupts for Playoff Career-High 26 Points in Game 2
Jaccob Slavin

Struggles in Game 1 Against Canadiens
Jakub Dobes

Sharp in Game 1 Victory
Cole Caufield

Bags Two Points in Impressive Road Win
Juraj Slafkovsky

Opens Conference Finals With Three-Point Performance
Nick Suzuki

Notches Three Assists in Game 1 Win Over Hurricanes
Ronald Acuña Jr.

Ronald Acuna Jr. Exits Early, X-Rays Come Back Negative
Jrue Holiday

Wants to Stay in Portland
Ayo Dosunmu

Timberwolves Hope to Bring Back Ayo Dosunmu
Dylan Harper

Considered Questionable for Friday Night
De'Aaron Fox

Listed as Questionable for Game 3
Jalen Williams

Questionable for Game 3 Against Spurs
Alex Tuch

Hopes to Remain in Buffalo
Sidney Crosby

Wants to Play for "as Many Years as Possible"
Troy Terry

Could Miss Start of Next Season Due to Hip Surgery
Arber Xhekaj

Scratched for Game 1 of Eastern Conference Finals
Jakub Dobes

Seeks More Success Against Hurricanes
Frederik Andersen

Looks to Stay Undefeated Thursday
Calvin Ridley

Not Taking Part in OTAs as Value Continues to Plummet
Robby Snelling

Will Undergo Tommy John Surgery
Devin Vassell

Contributes 22 Points in Wednesday's Loss
Stephon Castle

Tallies Team-High 25 Points in Game 2 Loss
Victor Wembanyama

Records Eighth Postseason Double-Double
Isaiah Hartenstein

Bounces Back With Double-Double
Valeri Nichushkin

Ends Scoring Slump in Game 1 Loss
Nathan MacKinnon

Extends Point Streak With an Assist
Jackson Merrill

Tweaks his Back on Wednesday, Pulled Early
CFB

Lincoln Riley Believes USC is Ready for Playoff Run
CFB

Notre Dame-Stanford Rivalry Renewed Through 2028
CFB

Ahmad Hardy Says He's "Back to the Road to Success"
CFB

Texas Tech Graduate Judge Recuses Himself from Brendan Sorsby Case
CFB

UCLA Tackle Jordan Davis Officially Eligible for 2026 Season
CFB

Bret Bielema Supports Significant College Football Playoff Expansion
Michael Thorbjornsen

Brings High Upside to CJ Cup Byron Nelson
Luke List

Carrying Poor Form Into CJ Cup Byron Nelson
Tom Kim

Hoping to Build on Strong Myrtle Beach Finish
PGA

Sungjae Im Brings Upside to TPC Craig Ranch
Billy Horschel

Looking for Turnaround at CJ Cup Byron Nelson
Adam Hadwin

Difficult to Trust at TPC Craig Ranch
Tony Finau

Looking for Consistency at TPC Craig Ranch
Luke Clanton

Searching for Form at CJ Cup Byron Nelson
Aaron Rai

Withdraws From CJ Cup Byron Nelson
Wyndham Clark

Can Wyndham Clark Find Form at CJ Cup?
Si Woo Kim

Looks To Stay Hot at CJ Cup
Scottie Scheffler

to Defend CJ Cup Byron Nelson Title This Week
Jordan Spieth

Looking For Victory at TPC Craig Ranch
PGA

Matti Schmid Looks to Keep Recent Momentum Going at TPC Craig Ranch
Brooks Koepka

a High-Upside Play at CJ Cup Byron Nelson
Yandy Díaz

Yandy Diaz Exits Early on Tuesday After Being Hit By Pitch
Chris Kirk

Continues Search For Putting Form at TPC Craig Ranch
Rasmus Hojgaard

Looking to Shake Off Poor Major Showing at TPC Craig Ranch
Joel Dahmen

is of No DFS Consideration This Week in Dallas
Pierceson Coody

is Not The Fun DFS Play He Used to Be
Gerrit Cole

to Make Season Debut on Friday Against Rays
Drake Baldwin

Braves Place Drake Baldwin on Injured List With Oblique Strain
CFB

Ezavier Crowell has Immediate Opportunity at Alabama
CFB

Mark Bowman a Day 1 Impact Player for USC?
CFB

Bill Belichick Says Relationship with First North Carolina Team "Wasn't Great"
CFB

Kemario Taylor a Breakout Candidate at Quarterback
CFB

Trinidad Chambliss the Undisputed Top SEC Quarterback Entering 2026?
CFB

Rocco Becht The "Unifier" of Penn State's Roster
Jackson Holliday

Orioles Reinstate Jackson Holliday From Injured List on Monday
Ronald Acuña Jr.

Braves Reinstate Ronald Acuna Jr. From Injured List on Monday
Jose Altuve

Astros Put Jose Altuve on Injured List With Oblique Strain
Corey Seager

Going on Injured List With Back Injury
Jeremy Peña

Jeremy Pena Reinstated and Starting on Monday Against Twins
Melquizael Costa

Drops Decision At UFC Vegas 117
Arnold Allen

Bounces Back
Daniel Santos

Suffers Second-Round TKO Loss
MMA

Dohoo Choi Wins His Third Consecutive Fight
Malcolm Wellmaker

Suffers His Second Loss In A Row
Juan Diaz

Scores Second-Round Submission
Christian Edwards

Defeated At UFC Vegas 117
CFB

Transfer Running Back Arnold Barnes Visiting Iowa State on Monday
Modestas Bukauskas

Gets Split-Decision Win
Jhostynxon Garcia

Expected to Join the Pirates on Tuesday
Colt Emerson

Mariners Promoting Top Prospect Colt Emerson to Major Leagues
Munetaka Murakami

Fantastic First Season Continues With Two More Homers
Cristopher Sánchez

Cristopher Sanchez Dazzles With 13-Strikeout Complete Game on Saturday
Blake Snell

to Undergo Elbow Surgery on Tuesday
Clay Holmes

Could Miss Around Three Months
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF