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Who Should I Start for Week 16? Fantasy Football outlooks for Harold Fannin Jr., Audric Estime, RJ Harvey, Jauan Jennings, Jaylen Waddle, Stefon Diggs, Jalen Coker, Isaiah Likely, Jalen Nailor.
Who Should I Start? Who Should I Sit? Some of the most common Week 16 fantasy football lineup decisions involve players like Harold Fannin Jr., Audric Estime, RJ Harvey, Jauan Jennings, Jaylen Waddle, Stefon Diggs, Jalen Coker, Isaiah Likely, Jalen Nailor. However, don't worry, we are here to help you make these decisions and build winning lineups in Week 16. Set your optimal fantasy football lineups for Week 16 of the 2025 NFL season. Our free Who Should I Start? tool will help make your fantasy football lineup decisions. Compare up to four NFL players, and we tell you who to start... all free! Get your winning lineups set, and make the right decisions.
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Fantasy Football Matchup Outlooks
Below are some fantasy football outlooks written by our NFL team here at RotoBaller, bringing you their fantasy football analysis and advice on which players to consider starting in Week 16:
Harold Fannin Jr., TE, Cleveland Browns
Cleveland Browns rookie tight end Harold Fannin Jr. is the lone bright spot in the Browns' offense heading into their Week 16 matchup against the Buffalo Bills at home. Over the last two games, the versatile tight end has 15 receptions for 162 yards and a touchdown on 25 targets. For the season, Fannin Jr. leads all Browns pass catchers in targets, receptions, yards, and touchdowns. With fellow tight end David Njoku (knee) ruled out for Week 16 and wide receiver Jerry Jeudy struggling to gain rapport with rookie quarterback Shedeur Sanders, Fannin Jr. will probably continue to dominate targets and see outsized opportunities.
Fannin Jr. is going to need volume going up against the Bills' defense, which routinely limits opposing tight ends to single-digit fantasy points and is the hardest matchup for tight ends in the league. Despite this brutal matchup and unreliable quarterback play from Sanders, Fannin Jr. is a TE1 and top-five tight end in Week 16, even with a precariously low ceiling.
Audric Estime, RB, New Orleans Saints
Fannin Jr. is going to need volume going up against the Bills' defense, which routinely limits opposing tight ends to single-digit fantasy points and is the hardest matchup for tight ends in the league. Despite this brutal matchup and unreliable quarterback play from Sanders, Fannin Jr. is a TE1 and top-five tight end in Week 16, even with a precariously low ceiling.
Audric Estime, RB, New Orleans Saints
New Orleans Saints running back Audric Estime looks set to have a significant role in New Orleans' backfield for the Week 16 matchup at home this Sunday against the visiting New York Jets. Rookie Devin Neal (hamstring) has been ruled out, and veteran Alvin Kamara (knee, ankle) has yet to practice since spraining his MCL back in Week 12. After Neal was injured in Sunday's upset win over the Carolina Panthers, Estime and Evan Hull split the backfield work, with Estime carrying the ball three times for 11 yards and catching all three of his targets for 39 yards. Hull had four totes for 12 yards but wasn't involved in the passing game.
While Estime is worthy of a waiver-wire pickup going into Week 16's favorable matchup against the Jets, keep in mind that he had just three carries all year going into last week. Additionally, rookie quarterback Tyler Shough will continue to be a factor in the Saints' ground game, as he's had at least six carries in each of his last four starts. At best, Estime will be a low-upside, touchdown-dependent RB3/flex for desperate fantasy managers this weekend if Kamara doesn't return.
RJ Harvey, RB, Denver Broncos
While Estime is worthy of a waiver-wire pickup going into Week 16's favorable matchup against the Jets, keep in mind that he had just three carries all year going into last week. Additionally, rookie quarterback Tyler Shough will continue to be a factor in the Saints' ground game, as he's had at least six carries in each of his last four starts. At best, Estime will be a low-upside, touchdown-dependent RB3/flex for desperate fantasy managers this weekend if Kamara doesn't return.
RJ Harvey, RB, Denver Broncos
Denver Broncos rookie running back R.J. Harvey (ribs) is participating in practice on Wednesday, according to Romi Bean of CBS Colorado. Harvey picked up a rib injury late in Denver's Week 15 win over the Green Bay Packers, but he seems to have avoided a major injury that would cost him any time. Head coach Sean Payton wasn't concerned with the injury, saying that "he's doing good" and should be good to go for Sunday's game against the Jacksonville Jaguars.
Payton noted to himself after the Packers game to get Jaleel McLaughlin more touches to manage Harvey's workload, but it's promising news that the rookie won't miss any time. He's been one of the best running backs in fantasy football since taking over lead duties with J.K. Dobbins (foot) out for the year, ranking as the RB6 in PPR points per game over the past four games. Harvey will project favorably again in Week 16 versus the Jaguars. UPDATE: Harvey was a full participant in Wednesday's practice.
Payton noted to himself after the Packers game to get Jaleel McLaughlin more touches to manage Harvey's workload, but it's promising news that the rookie won't miss any time. He's been one of the best running backs in fantasy football since taking over lead duties with J.K. Dobbins (foot) out for the year, ranking as the RB6 in PPR points per game over the past four games. Harvey will project favorably again in Week 16 versus the Jaguars. UPDATE: Harvey was a full participant in Wednesday's practice.
Jauan Jennings, WR, San Francisco 49ers
San Francisco 49ers wide receiver Jauan Jennings tallied two more touchdowns in Week 15 but again turned in a low-yardage game with just 37 yards against the Titans. Jennings has at least one touchdown in five of the 49ers' last six games, but is averaging 47.2 yards per game during that stretch. He could be in store for a more productive day in Week 16, when San Francisco faces the Indianapolis Colts, which has surrendered more receiving yards to slot targets than any other team.
Jennings has played out of the slot more frequently than any other receiver for San Francisco this season. If Ricky Pearsall (knee/ankle) is unable to play, then Jennings would likely see a slight bump in targets on Monday, as well. Jennings projects as a WR2 and can be plugged into starting lineups in Week 16.
Stefon Diggs, WR, New England Patriots
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Jennings has played out of the slot more frequently than any other receiver for San Francisco this season. If Ricky Pearsall (knee/ankle) is unable to play, then Jennings would likely see a slight bump in targets on Monday, as well. Jennings projects as a WR2 and can be plugged into starting lineups in Week 16.
Stefon Diggs, WR, New England Patriots
New England Patriots wide receiver Stefon Diggs will look to get back on track in Week 16 against the Baltimore Ravens following a disappointing three-game stretch. Over his last three contests, Diggs has played fewer than half of the offensive snaps with just 11 targets, eight catches, 72 yards, and zero touchdowns. He ranks as the overall WR82 in full-PPR fantasy points per game during that span. It has been a frustrating stretch for a veteran receiver who had previously strung together five consecutive contests with double-digit fantasy points.
This week, he'll take on a Ravens secondary that has allowed the ninth-fewest fantasy points to slot receivers in 2025. That doesn't bode well for Diggs, who has played 49.8% of his snaps in the slot and has the 19th-most slot snaps in the NFL this year. Managers can absolutely justify benching the 32-year-old in fantasy leagues with 12 or fewer teams. He ranks as the overall WR31 in RotoBaller's latest fantasy football rankings for Week 16.
This week, he'll take on a Ravens secondary that has allowed the ninth-fewest fantasy points to slot receivers in 2025. That doesn't bode well for Diggs, who has played 49.8% of his snaps in the slot and has the 19th-most slot snaps in the NFL this year. Managers can absolutely justify benching the 32-year-old in fantasy leagues with 12 or fewer teams. He ranks as the overall WR31 in RotoBaller's latest fantasy football rankings for Week 16.
Who Should I Start Tool
You can also see the Who Should I Start tool here.
Week 16 Player Decisions. Today's focus is on specific players - Harold Fannin Jr., Audric Estime, RJ Harvey, Jauan Jennings, Jaylen Waddle, Stefon Diggs, Jalen Coker, Isaiah Likely, Jalen Nailor. These are some of the most common searches for fantasy football lineups in Week 16.
Using The Tool. This is a simple tool but very powerful. The first step is to enter the player names that you want to compare. In the first box, search for the first player name. In the second box, search for the second player name. Compare up to four NFL players at once, and then click the Who To Start? button to see who the recommended starts are based on weekly fantasy football matchups.
Improvements For Who Should I Start? You may have noticed that our 'Who Should I Start?' tool has gotten an overhaul. We've added lots of great features for you to give you as much information as possible to win your fantasy football matchups each week. You'll see NFL player tiles with headshots and bye weeks, stats, projections, strength of schedule, players news, and enhanced search results with data to compare with a slick new interface. We hope you enjoy!
How It Works. Each week our RotoBaller staff puts together their weekly fantasy football rankings and projections based on their research. That information is the core data that is powering the decision-making in this tool. When you search for player names, you will only see those players who are ranked. If someone is out for the week, they will not appear in the search results.
Scoring Formats. Fantasy football managers play in various types of leagues, and this tool allows you to choose whether it's PPR scoring, Half-PPR scoring, or Standard (Non-PPR) scoring. The second thing you want to do, is to select the scoring format. There are three small radio buttons (small circle), so click on the scoring format you prefer. The results may vary based on the scoring format you select.
Popular Week 16 Searches. Curious to see some tough lineup decisions for Week 16 (2025)? Below you will find a list of some popular Who Should I Start? searches that RotoBaller readers are looking at this week. Click any of the links to see the result and recommendation.
Popular Week 16 Searches - Start/Sit Player Comparisons
Below are some popular searches and comparisons from our Who To Start tool for Week 16 for Harold Fannin Jr., Audric Estime, RJ Harvey, Jauan Jennings, Jaylen Waddle, Stefon Diggs, Jalen Coker, Isaiah Likely, Jalen Nailor:
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Christian Kirk
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Ja'Tavion Sanders
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Konata Mumpfield
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Van Jefferson
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Isaac TeSlaa
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Amon-Ra St. Brown
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CeeDee Lamb
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Ja'Marr Chase
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Jaxon Smith-Njigba
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Nico Collins
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Mike Evans
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George Pickens
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