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Who Should I Start for Week 16? Fantasy Football outlooks for Jacoby Brissett, C.J. Stroud, Brock Purdy, Joe Burrow, J.J. McCarthy, Jaxson Dart, Bo Nix, Trevor Lawrence, Justin Herbert, Dak Prescott.
Who Should I Start? Who Should I Sit? Some of the most common Week 16 fantasy football lineup decisions involve players like Jacoby Brissett, C.J. Stroud, Brock Purdy, Joe Burrow, J.J. McCarthy, Jaxson Dart, Bo Nix, Trevor Lawrence, Justin Herbert, Dak Prescott. However, don't worry, we are here to help you make these decisions and build winning lineups in Week 16. Set your optimal fantasy football lineups for Week 16 of the 2025 NFL season. Our free Who Should I Start? tool will help make your fantasy football lineup decisions. Compare up to four NFL players, and we tell you who to start... all free! Get your winning lineups set, and make the right decisions.
Compare up to four players and we'll tell you who to start...
Fantasy Football Matchup Outlooks
Below are some fantasy football outlooks written by our NFL team here at RotoBaller, bringing you their fantasy football analysis and advice on which players to consider starting in Week 16:
Jacoby Brissett, QB, Arizona Cardinals
It has helped that the Cardinals have been playing from behind quite often, forcing Brissett to pass frequently. Fantasy managers in need of a streaming option for Week 16 should take a hard look at Brissett. He'll draw a plus matchup against the Atlanta Falcons defense this weekend. Brissett has been posting nearly top-10 QB numbers every week since he took over under center, and he is a viable option for fantasy managers in need of help.
C.J. Stroud, QB, Houston Texans
The third-year signal-caller is emerging as a strong streaming option with the Texans' offense finding its best form and an ideal Week 16 matchup on deck against the Las Vegas Raiders. While he doesn't add much value as a runner, Stroud is showing the passing upside to be worth consideration as a plug-and-play starter this week.
Brock Purdy, QB, San Francisco 49ers
Purdy has battled multiple injuries so far in 2025, but he seems to be hitting his stride down the stretch of the season. Purdy has completed at least 70% of his pass attempts in three out of his last four starts, leading San Francisco to a 4-0 record and an average of 31 points per game over that stretch. The 49ers will travel to Indianapolis to take on the Colts in Week 16.
Joe Burrow, QB, Cincinnati Bengals
The former first overall pick threw for 545 yards, six touchdowns, and two interceptions on 49-for-82 passing in his first two games back before going 25-for-39 for 225 yards, no touchdowns, and two picks in Sunday's 24-0 shutout loss to the division-rival Baltimore Ravens. Burrow has thrown costly pick-sixes in each of the last two weeks and seemed to question his long-term future in Cincy last week. For fantasy football purposes, Burrow will be a strong QB1 option in Week 16 versus the Miami Dolphins.
J.J. McCarthy, QB, Minnesota Vikings
He has six total touchdowns and just one turnover in those two games, and he has a great matchup to keep his momentum going in Week 16 as the Vikings head to New York and face the Giants. If you're looking for a second QB or are desperate for a streaming option, McCarthy's rushing potential makes him a solid snatch and start option this week.
Who Should I Start Tool
You can also see the Who Should I Start tool here.
Week 16 Player Decisions. Today's focus is on specific players - Jacoby Brissett, C.J. Stroud, Brock Purdy, Joe Burrow, J.J. McCarthy, Jaxson Dart, Bo Nix, Trevor Lawrence, Justin Herbert, Dak Prescott. These are some of the most common searches for fantasy football lineups in Week 16.
Using The Tool. This is a simple tool but very powerful. The first step is to enter the player names that you want to compare. In the first box, search for the first player name. In the second box, search for the second player name. Compare up to four NFL players at once, and then click the Who To Start? button to see who the recommended starts are based on weekly fantasy football matchups.
Improvements For Who Should I Start? You may have noticed that our 'Who Should I Start?' tool has gotten an overhaul. We've added lots of great features for you to give you as much information as possible to win your fantasy football matchups each week. You'll see NFL player tiles with headshots and bye weeks, stats, projections, strength of schedule, players news, and enhanced search results with data to compare with a slick new interface. We hope you enjoy!
How It Works. Each week our RotoBaller staff puts together their weekly fantasy football rankings and projections based on their research. That information is the core data that is powering the decision-making in this tool. When you search for player names, you will only see those players who are ranked. If someone is out for the week, they will not appear in the search results.
Scoring Formats. Fantasy football managers play in various types of leagues, and this tool allows you to choose whether it's PPR scoring, Half-PPR scoring, or Standard (Non-PPR) scoring. The second thing you want to do, is to select the scoring format. There are three small radio buttons (small circle), so click on the scoring format you prefer. The results may vary based on the scoring format you select.
Popular Week 16 Searches. Curious to see some tough lineup decisions for Week 16 (2025)? Below you will find a list of some popular Who Should I Start? searches that RotoBaller readers are looking at this week. Click any of the links to see the result and recommendation.
Popular Week 16 Searches - Start/Sit Player Comparisons
Below are some popular searches and comparisons from our Who To Start tool for Week 16 for Jacoby Brissett, C.J. Stroud, Brock Purdy, Joe Burrow, J.J. McCarthy, Jaxson Dart, Bo Nix, Trevor Lawrence, Justin Herbert, Dak Prescott:
No matching players.More Fantasy Football Analysis
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