When Will Joe Mixon Return and Be Back? Fantasy Football Injury Update for Week 10 (2025)

by Andy Smith

Link copied to clipboard!

When will Joe Mixon return and play? Will Joe Mixon be back again this season? Read the latest Joe Mixon injury updates and return date for Week 10 (2025).

In This Article hide

2. Joe Mixon Fantasy Football Outlook

3. Who Should I Start Tool

5. More Fantasy Football Analysis

Houston Texans running back Joe Mixon (foot) has yet to take the field this season after suffering a foot injury during the offseason. Mixon has been on the non-football injury/reserve list since the start of the regular season.

With the season now past the halfway point, should managers expect Mixon to return to the field this season?

When will Mixon return to action, and what is his fantasy football outlook when he does? Let's dive in.

Be sure to check all of our fantasy football rankings for 2025:

Joe Mixon Injury Update

Entering Week 10, there is no significant update regarding Mixon's availability. In fact, the Texans only provide minor updates in October, which does not suggest he is anywhere close to a return. Last month, the team's general manager, Nick Caserio, stated that his status was "in limbo" for the remainder of the season.

Given the lack of updates and the unclear timeline, managers should expect Mixon to remain on the shelf for the foreseeable future.

Since he has yet to step into the practice field or make any significant progress in his rehab plan, managers should not expect him to be in contention to return to the lineup anytime soon.

No Timetable for Joe Mixon's Return https://t.co/Hib7RlCrYy

— RotoBaller NFL (@RotoBallerNFL) October 20, 2025

Joe Mixon Fantasy Football Outlook

Due to the lack of progress Mixon has made, managers should not expect him to return this season. As a result, managers should feel comfortable cutting ties with the veteran running back in all leagues ahead of Week 10. Even though he is IR eligible on most platforms, he will face an uphill battle to return this season and is not worth holding in a reserve post.

Instead, managers should look to players like Brandon Aiyuk (knee), who will have a clear path back from the IR this season. When looking at potential running backs, they should pivot to high-end RB2 handcuffs like Blake Corum, Isaiah Davis, Ray Davis, or Sean Tucker. With James Cook (foot) now sidelined with injuries and Bucky Irving (foot/shoulder) still in danger of missing time, both Davis and Tucker could see more opportunities in the immediate future.

Ray Davis Could Have Expanded Role in Week 10 https://t.co/oGJGhpszS2

— RotoBaller NFL (@RotoBallerNFL) November 5, 2025

Both Davis and Corum carry low standalone upside but could enter high-end RB2 starter if their team's starter were to miss time. In Houston, managers should expect Nick Chubb and Woody Marks to continue operating as the lead options in the backfield for the remainder of their regular season.

Who Should I Start Tool

Not sure who to start? Check out the Who Should I Start tool:

Who Should I Start for Week 10?

PPR Half-PPR STD

Compare up to four players and we'll tell you who to start...

Who To Start?

Reset

Choose From The Top Ranked Players

Overall

DST

Rookies

Popular Searches

Overall

DST

Rookies

Who Should I Start? Who Should I Sit? Deciding who to start instead? Some common Week 10 fantasy football lineup decisions are regarding players like Tyrone Tracy Jr., Rico Dowdle, Quentin Johnston, Kayshon Boutte. But not to worry, we are here to help make these decisions and build winning lineups in Week 10. Set your optimal fantasy football lineups for Week 10 of the 2025 NFL season. Our free Who Should I Start? tool will help make your fantasy football lineup decisions. Compare up to four NFL players, and we tell you who to start... all free! Get your winning lineups set, and make the right decisions.

Week 10 Player Decisions. Today's focus is on specific players - Tyrone Tracy Jr., Rico Dowdle, Quentin Johnston, Kayshon Boutte. These are some of the most common searches for fantasy football lineups in Week 10.

Using The Tool. This is a simple tool but very powerful. The first step is to enter the player names that you want to compare. In the first box, search for the first player name. In the second box, search for the second player name. Compare up to four NFL players at once, and then click the Who To Start? button to see who the recommended starts are based on weekly fantasy football matchups.

Improvements For Who Should I Start? You may have noticed that our 'Who Should I Start?' tool has gotten an overhaul. We've added lots of great features for you to give you as much information as possible to win your fantasy football matchups each week. You'll see NFL player tiles with headshots and bye weeks, stats, projections, strength of schedule, players news, and enhanced search results with data to compare with a slick new interface. We hope you enjoy!

How It Works. Each week our RotoBaller staff puts together their weekly fantasy football rankings and projections based on their research. That information is the core data that is powering the decision-making in this tool. When you search for player names, you will only see those players who are ranked. If someone is out for the week, they will not appear in the search results.

Scoring Formats. Fantasy football managers play in various types of leagues, and this tool allows you to choose whether it's PPR scoring, Half-PPR scoring, or Standard (Non-PPR) scoring. The second thing you want to do, is to select the scoring format. There are three small radio buttons (small circle), so click on the scoring format you prefer. The results may vary based on the scoring format you select.

Popular Week 10 Searches. Curious to see some tough lineup decisions for Week 10 (2025)? Below you will find a list of some popular Who Should I Start? searches that RotoBaller readers are looking at this week. Click any of the links to see the result and recommendation.

Popular Week 10 Searches - Start/Sit Player Comparisons

Deciding who to start instead? Below are some popular Week 10 searches and comparisons from our 'Who To Start' tool for Tyrone Tracy Jr., Rico Dowdle, Quentin Johnston, Kayshon Boutte compared to others:

Jacory Croskey-Merritt