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Houston Texans running backs Joe Mixon (ankle) and Dameon Pierce (hamstring) did not practice on Wednesday, according to Aaron Wilson of KPRC2. Mixon suffered an ankle injury during Week 2 and has not returned to the field since. Pierce suffered a hamstring injury following Week 1 and has also remained sidelined. As a result, Cam Akers and Dare Ogunbowale have served as the top backs over the past two weeks. Fantasy managers should continue to monitor Mixon's and Pierce's status before their Week 5 matchup against the Buffalo Bills. Even though Akers has averaged just 37 yards on the ground while serving as the starter, he could be a solid flex option if Mixon and Pierce remain out this weekend.--Andy Smith - RotoBaller
Source: Aaron Wilson
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