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Cowboys vs. 49ers Betting Picks - Free NFL Best Bets, Odds, Predictions for the Divisional Round

Christian McCaffrey - Fantasy Football Rankings, NFL Injury News, DFS Lineup Picks

Free NFL betting picks, odds, predictions for the Cowboys vs. 49ers in the Divisional Round (2023). Our best bets and top NFL picks for moneylines, over/unders and more.

Welcome RotoBallers to our betting picks for the Dallas Cowboys vs. San Francisco 49ers, another article in our weekly series of free NFL betting picks for every game on the schedule. This free NFL betting breakdown article is for Sunday, January 22nd, 2022.

Attention fellow sports bettors! We have some exciting news to share as we are now partnered with various sportsbooks and have some sweet sports betting promo offers and freebies for you. Get your deposit bonus and also a year of free RotoBaller Premium access for all sports and all tools ($450 value), when you sign up with a new account today! After you're signed up, use our picks in this article for spreads, totals, and props to win big.

In addition to all of our other betting content and advice, we have now added weekly betting analysis articles and betting recommendations for each NFL game. Every single game on the NFL schedule will have its own betting analysis, betting breakdown and betting picks, every single week! We hope you enjoy, and good luck RotoBallers.

Be sure to check all of our fantasy football rankings for 2025:

 

Today's Betting Overview - Cowboys @ 49ers

The Cowboys take on the 49ers on Sunday, January 22nd at Levi's Stadium, Santa Clara. RotoBaller provides free handicapping picks and odds for all NFL games throughout the 2022 season.

  • Matchup: Dallas Cowboys (12-5) vs. San Francisco 49ers (13-4)
  • Date: Sunday, January 22nd, 2022
  • Time: 6:30 PM ET
  • Venue: Levi's Stadium

 

Today's NFL Sportsbook Odds - Cowboys @ 49ers

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Dallas Cowboys - NFL Betting Analysis

In the Divisional Round, the Cowboys will look to keep things rolling after picking up a 31-14 over the Tampa Bay Buccaneers. Besides winning straight up, the Cowboys also came away with an ATS win as the -3.0 point favorite. With an over-under betting line of 45.5, the two teams fell below that figure as they combined for 45. On their way to picking up a 17-point win, Dallas held an 18-point lead heading into the 4th quarter at 24-6. Through 18 games, the Cowboys have an ATS record of 11-7. So far, they have an over-under record of 9-9. This week's betting total of 46.0 is right in line with their previous games.

As the Cowboys prepare to take on San Francisco, they have played well on offense, ranking 4th in points per game at 27.8. Against the 49ers, they will be facing the NFL's 1st ranked defense. Even though the Cowboys head into this week's game ranked 14th in pass yards per game and have a tough defensive matchup, we project them to have an above-average performance in the passing game. A key matchup to watch through the game is if Dallas will continue to run the ball well, averaging 134.8 yards per game on the ground.

 

San Francisco 49ers - NFL Betting Analysis

Last week, the 49ers picked up a Wild Card Weekend win as they took down the Seahawks by a score of 41-23. Besides winning straight up, the 49ers also came home with an ATS win as the -9.5 point favorites. The teams combined for a total of 64 points, which surpassed the over-under betting line of 42. On their way to picking up an 18 point win, San Francisco held a 6-point lead heading into the 4th quarter at 23-17. Through 18 games, the 49ers have an ATS record of 12-6. So far, they have an over-under record of 10-8. This week's betting total of 46.0 is slightly higher than the line in their previous games.

Heading into this week's matchup, the 49ers' offense is averaging 27.3 points per game, placing them 6th in the NFL. On the other side, they will be facing the 6th-ranked scoring defense. This week, look for the 49ers are facing a secondary ranked 10th in passer rating allowed. On the ground, the 49ers should be in line for a good performance, as they are one of the better-rushing team's in the league and are facing a defense that has its problem stopping the run.

 

Today's NFL Betting Pick - Cowboys vs. 49ers

Dallas comes into the game looking to continue their recent success over San Francisco, as they have won 2 of their last 3 matchups. The two teams have combined to average 54.7 points per game in their last 3 meetings. Last year, the Cowboys and 49ers did not play each other.

The Dallas Cowboys have performed well vs the spread in recent games, going 2-1. The Cowboys' offense has averaged 32.7 points per game over the 3 most recent meetings with San Francisco, compared to the 49ers at 22.0.

Spanning across their last 3 games, Dallas has gone 2-1. Their strong play has also resulted in a strong ATS mark of 2-1 (last 3).

In their last 3 road games, Dallas has averaged 21.3 points per game while allowing 17.7. The team's record in this stretch was 2-1 while going 2-1.

Over their last 3 regular season games, the 49ers have gone 3-0 straight up. The team has also been excellent vs the spread, going 2-1. Their over-under record in these games was 3-0

San Francisco has played well in their previous 3 home games, going 3-0 straight up. In this stretch, they averaged 38.67 points per game while allowing 18.7. The team also performed well vs the spread at 3-0.

Recommended ATS Betting Pick: 49ers -4.0

Recommended OU Betting Pick: Over 46.0



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