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Yahoo Lineup Picks (Week 10) - NFL DFS Advice

Hey there RotoBallers! In this article, I will be taking a look at some of my favorite Yahoo DFS lineups picks for the Week 10 slate.

These DFS picks are based on a multitude of factors including matchup, talent, recent performance, Vegas odds, and pricing on Yahoo.

Generally, I will try to outline a top option at each position along with a value option with a chance to at least hit value. Let's get to it!

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Quarterback Picks for Yahoo DFS

Dak Prescott, Dallas Cowboys @ ATL, $35

Prescott just continues to be one of the most consistent fantasy quarterbacks in the league. The second-year signal caller has combined for at least three total touchdowns (rushing and passing) in five of his past six games. He has been extremely efficient running the ball this season, averaging 3.25 rushing attempts and 24.4 rushing yards per game along with four total rushing scores. This continues to give him a high weekly floor in addition to his weekly QB1 ceiling. The Cowboys are projected to score over 22 points this weekend in a game with a high 50-point over/under. Prescott is the quarterback of choice if you plan to pay up at the position this weekend.

Ryan Fitzpatrick, Tampa Bay Buccaneers vs. NYJ, $21

Fitzpatrick will step in as Tampa Bay's starting quarterback for the next few weeks while Jameis Winston is sidelined by a shoulder issue. While Fitzpatrick didn't fare well against the Saints in relief of Winston in Week 9, he will find things much easier to navigate against the Jets in Week 10. New York is struggling against the pass this season, ranking 21st in pass defense DVOA and allowing the fourth-most fantasy points per game to the position on Yahoo. This is Ryan Fitzpatrick we are talking about here, so he can't be called a "safe" play, but he is just $1 over the minimum price on Yahoo and the matchup sets up for him to return excellent value in Week 10.

 

Running Back Picks for Yahoo DFS

LeSean McCoy, Buffalo Bills vs. NO, $34

McCoy disappointed against the Jets in Week 9 with just 25 rushing yards, but New York has been pretty stout against the run this season, having allowed just one rushing score to the position since Week 2. McCoy should bounce back in a big way against a Saints defense that is much improved against the pass but is still vulnerable against enemy backs. New Orleans' strong secondary should help funnel extra work to McCoy, setting him up for a strong outing in Week 10. McCoy maintains a high weekly floor as he has been one of the more active running backs in the passing game this year, averaging 4.75 receptions and just over 30 receiving yards per game. He's a fantastic play if you are able to save enough elsewhere to fit him into lineups.

Christian McCaffrey, Carolina Panthers vs. MIA, $19

McCaffrey enjoyed a career-high 15 rushing attempts and 20 total touches against the Falcons in Week 9. He surely saw a few extra rushing attempts thanks to Jonathan Stewart losing two fumbles, but McCaffrey made the most of his opportunity, posting 4.4 rushing yards per attempts, a season-high for him. The rookie runner continues to be one of the heaviest-targeted satellite backs in the league, averaging six receptions and just over 45 receiving yards per game. He hasn't seen less than six targets since Week 2 against the Buffalo Bills and, similar to McCoy, all the work in the passing game keeps his weekly floor up. McCaffrey projects as an RB1 in fantasy this weekend but he is priced as the RB16 on Yahoo. Be sure to take advantage of this pricing discrepancy.

 

Wide Receiver Picks for Yahoo DFS

Golden Tate, Detroit Lions vs. CLE, $20

Some pretty nice values at the wide receiver position opened up on Yahoo this week. Tate sets up as one of the top value options as he checks in at $20, just the 24th-highest priced wide receiver on the slate. Tate draws an excellent matchup against a leaky Cleveland pass defense this weekend. The Browns' pass defense ranks just 28th in the league in DVOA this season, setting Tate up for a possible huge game. Furthermore, Tate runs 80% of his routes out of the slot, meaning he will avoid coverage from Jason McCourty, who has been Cleveland's top defensive back this season.

Devin Funchess, Carolina Panthers vs. MIA, $19

Funchess checks in as another excellent value on Yahoo. With Kelvin Benjamin now in Buffalo, Funchess is now operating as Carolina's No. 1 receiver and he draws a fantastic matchup against a weak Miami pass defense. Funchess is averaging over seven targets per game and hasn't dipped below six since way back in Week 1. The Dolphins' pass defense ranks just 30th in the league in DVOA and will send Cordrea Tankersley and Xavien Howard out there to try to slow Funchess. Howard has been especially burnable this season, earning just a 38.1 grade from Pro Football Focus. Plugging both Tate and Funchess into lineups this weekend should allow fantasy owners to fit a high-priced receiver in the third WR spot on Yahoo.

 

Tight End Picks for Yahoo DFS

Evan Engram, New York Giants @ SF, $21

Engram draws what appears to be a tough matchup against the 49ers but he remains one of the top tight end options on the slate. San Francisco's defense is the best-rated unit in the league in DVOA against tight ends but they have started to show some cracks of late, having allowed a tight end touchdown in three straight games. With the depleted pass-catching corps on the Giants, Engram and Sterling Shepard are New York's two most consistent pass-catching options against a favorable Week 10 opponent.

Garrett Celek, San Francisco 49ers vs. NYG, $10

If you can't set aside enough salary to make Engram work in your lineups, look no further than the tight end on the other side of the field this Sunday. Garrett Celek stands to see an increased role as one of the 49ers' last remaining healthy tight ends. San Francisco ruled George Kittle out on Monday and placed backup tight end Cole Hikutini on injured reserve. That leaves Celek to operate as the team's primary tight end against a Giants defense that has been famously bad against the position this season. New York has allowed a tight end to score in each of their eight games played this year and is allowing the most fantasy points per game to the position.

 

Defense/Special Teams Pick for Yahoo DFS

Carolina Panthers vs. MIA, $17

The Panthers defense has been a better real-life defense than they have been in fantasy but the matchup this week is too good to ignore. Carolina is installed as a massive 10-point home favorite in a game with an extremely low 40-point over/under. Furthermore, the Dolphins offense has been the gift that keeps on giving to opposing fantasy defenses this season, allowing the seventh-most fantasy points per game. This sets up as a perfect spot to deploy the Panthers defense in daily leagues.

 

More Week 10 DFS Analysis

 

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REAL-TIME FANTASY NEWS

Jimmy Butler III

Will Not Play Against Thunder
Aaron Jones Sr.

Won't Play in Week 18
Seth Curry

Sidelined on Friday Vs. Thunder
Omarion Hampton

Ruled Out for Week 18
Draymond Green

Getting a Rest Day Against Thunder
Dallas Goedert

Ruled Out With Knee Injury
J.J. McCarthy

Will Start in Week 18
Jerami Grant

Still Watching From Sidelines on Friday
Javonte Williams

Ruled Out for Sunday
Zach Collins

Remains Out on Friday
Michael Porter Jr.

Remains Sidelined on Friday
Cam Thomas

Resting on Friday
Nicolas Claxton

Ruled Out for Friday's Game
Alvin Kamara

Will Remain Out in Week 18
Saddiq Bey

Won't Suit Up on Friday
Davante Adams

Questionable to Play in Week 18
Derik Queen

is Unavailable on Friday
Trae Young

Won't Play on Friday
Kyren Williams

Questionable to Play in Week 18
Kyle Pitts Sr.

Questionable for Sunday
Drake London

Questionable for Season Finale
Harold Fannin Jr.

Ruled Out in Week 18
Harold Fannin Jr.

Unlikely to Play in Week 18
Jaylen Waddle

Questionable to Play in Week 18
Josh Allen

"Good to Go" Vs. Jets
CFB

Joey Aguilar Undergoes Surgery to Remove Tumor on Friday
CFB

Texas the "Team to Beat" for Transfer Running Back Isaac Brown
CFB

Rocco Becht to Follow Matt Campbell to Penn State?
CFB

Texas Targeting Cam Coleman in Transfer Portal
CFB

Former Texas Running Back CJ Baxter Visiting Kentucky
CFB

Beau Pribula Visiting Virginia Tech, Georgia Tech
Derik Queen

Facing First Career Absence Friday
Saddiq Bey

May Sit Out Friday's Game
Grayson Allen

Questionable Friday
Moussa Diabaté

Moussa Diabate Iffy for Friday
Miles Bridges

Likely to Return Friday
De'Andre Hunter

May Miss Second Straight Game Due to Illness
Mitchell Robinson

at Risk of Missing Another Contest Friday
Devin Vassell

Remains Sidelined Friday
Draymond Green

Resting on Friday
Stephen Curry

Questionable Friday
Sebastian Aho

Records Season-High Five Points Thursday
Auston Matthews

Opens 2026 With Four-Point Effort
Dylan Guenther

Posts First Career Hat Trick During Four-Point Night
Josh Anderson

Exits Early After Scoring
Bo Horvat

Sustains Lower-Body Injury Thursday
Noah Laba

Out Week-to-Week
Conor Sheary

Lands on Long-Term Injured Reserve
Bo Bichette

Yankees Showing Interest in Bo Bichette
George Kittle

Listed as Questionable for Week 18
Amon-Ra St. Brown

Trending Towards Playing
Miles Wood

Blue Jackets Place Miles Wood on Injured Reserve
Dak Prescott

May Not Play Full Game in Week 18
Conor Garland

to Miss One Week
Marco Rossi

to Miss at Least One Week
Yegor Chinakhov

Set for Penguins Debut Thursday
Tanner McKee

Will Start for Eagles in Week 18
Shayne Gostisbehere

Misses Third Consecutive Game Thursday
Auston Matthews

Returns From One-Game Absence
Josh Allen

Trending Towards Resting in Week 18
William Nylander

Remains Out Thursday
Lamar Jackson

Will Officially Return in Week 18
Houston Astros

Astros Sign Tatsuya Imai to Three-Year Deal
Jordan Love

Clears Concussion Protocol, Won't Start in Week 18
Tom Wilson

Wraps Up 2025 With Gordie Howe Hat Trick
Valeri Nichushkin

Nets Second Career Hat Trick
Frank Vatrano

to Miss Six Weeks With Shoulder Injury
Conor Sheary

Noah Laba Exit With Injuries Wednesday
Brayden McNabb

Suffers Upper-Body Injury Wednesday
Miles Wood

Exits Early Wednesday
Gavin Brindley

Sustains Upper-Body Injury
CFB

Lane Kiffin Interested in Sam Leavitt, Brendan Sorsby at LSU
CFB

Deuce Knight Officially Entering Transfer Portal
CFB

Kewan Lacy Expected to Be Full-Go Against Georgia
CFB

Chip Kelly Named Northwestern Offensive Coordinator
CFB

Penn State Working to Hire D'Anton Lynn as Next Defensive Coordinator
CFB

Omar Cooper Expected to be Full-Go for Rose Bowl
CFB

Marcus Freeman Staying with Notre Dame for 2026 Season
CFB

Star Wideout Cam Coleman Entering Transfer Portal
CFB

Jay Hill Expected to be Next Michigan Defensive Coordinator

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