🦃 BLACK FRIDAY - SAVE 50% WITH CODE THANKS
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

Will James Cook Play Tonight? Fantasy Football Injury Update For 'Monday Night Football'

James Cook - Fantasy Football Rankings, Draft Sleepers, NFL Injury News

Is James Cook playing on "Monday Night Football" or is he out? Is Cook injured or healthy for Week 6 MNF? John Johnson analyzes the latest injury news.

Buffalo Bills running back James Cook is having a fantastic season. He's a near-lock to score double-digit fantasy points when he plays a full game, and he's averaged a touchdown for every game he's played so far. He's the engine of his offense and has the trust of his quarterback and the offensive staff.

He has an excellent role and is the primary running back for all situations. The other running backs seem to come in just to give him a break a few times a game, which is normal for most players. He dominates the snaps and opportunities at his position and there's little threat that he will lose his prominent position in the offense.

However, he's listed on the team's injury report ahead of Week 6. So will James Cook play tonight and is he healthy?

Be sure to check all of our fantasy football rankings for 2025:

 

James Cook Fantasy Football Injury Update

UPDATE: Cook has been ruled OUT

Cook is currently suffering from a toe injury he picked up in Week 5 when his foot slammed onto the turf after he was tackled by a Houston Texans defender, but reports state he is likely good to go. He missed practice altogether on Thursday and Friday but upgraded to a limited participant on Saturday, which is a good sign.

Cook has stated that he plans to play Monday when the Bills take on the New York Jets on the road. It's unknown the exact severity of his injury or whether he'll be load-managed this game, and it's not completely clear if he will play, as he's listed as "questionable" on the injury report. He's reportedly trending upwards, though.

Fantasy managers will likely need to check for updates leading up to the game, and the final list of active players will tell us whether he will be held out or not.

 

James Cook Fantasy Football Injury Impact

He could see a limited workload due to his injury, but he's played far better than the other players he shares the running back room with, so he may not be restricted much. Toe injuries are tricky, and fantasy managers aren't working with much information here. He's still worth starting due to his upside.

Cook's fantasy managers should consider picking up backup Ray Davis. If the lead back ends up being inactive, the rookie will likely carry most of the load. It's a tough matchup against a stingy Jets defense, but there aren't many other options since it's Monday, and all games but one have already been played.

Whichever running back ends up starting for Buffalo is worth a start in most fantasy leagues this week.



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Fantasy Football Analysis

POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Davante Adams

Catches Two Touchdowns in Sunday Night Win
Baker Mayfield

has Sprained Shoulder, Will Undergo MRI Monday
Las Vegas Raiders

Raiders Fire Offensive Coordinator Chip Kelly
Ryan Helsley

Tigers Eyeing Ryan Helsley as a Starter
Quinshon Judkins

Salvages his Day With Two Trips to the End Zone
Alvin Kamara

Dealing With MCL Sprain, Timetable Unclear
Michael Wilson

has Double-Digit Catches, Over 100 Yards for Second Straight Week
Baker Mayfield

Doubtful to Return on Sunday Night With Shoulder Injury
A.J. Brown

Delivers Vintage Performance in Week 12
George Pickens

at the Center of Cowboys Offense Once Again
Dan Hooker

Suffers Second-Round Submission Loss
Marcus Semien

Shipped to the Mets on Sunday
Alvin Kamara

Getting an MRI on His Knee
Arman Tsarukyan

Gets Submission Win
Brandon Nimmo

Traded to Texas
Belal Muhammad

Loses Back-to-Back Fights
Aaron Gordon

Sidelined 4-6 Weeks with Hamstring Strain
Belal Muhammad

Ian Machado Garry Outpoints Belal Muhammad
Chris Godwin

Officially Active for Sunday Night Football in Week 12
Alonzo Menifield

Suffers First-Round Knockout Loss
Kareem Hunt

Totals 33 Touches in Productive Outing Sunday
Volkan Oezdemir

Gets Back In The Win Column
Chimere Dike

Scores Long Special Teams Touchdown in Week 12
Jack Hermansson

Gets Knocked Out
Jack Hermansson

Myktybek Orolbai Knocks Out Jack Hermansson
Shamil Gaziev

Suffers First-Round Knockout Loss
DJ Moore

Scores Twice in Narrow Win at Home
Waldo Cortes-Acosta

Shines At UFC Qatar
Dereck Lively II

Out with Foot Issue Again
Tagir Ulanbekov

Suffers Third-Round Submission Loss
Anthony Davis

Doubtful With Calf Strain Against Miami
Derrick Henry

Rushes for Two Scores in Week 12 Victory
Kyoji Horiguchi

Makes Triumphant UFC Return
MON

Alexandre Texier Joins Canadiens
Goga Bitadze

a Very Late Scratch on Sunday Night
Rashee Rice

Goes for Nearly 150 Yards in Win Over Colts
Ryan Dunn

Ruled Out with Wrist Sprain
Jason Dickinson

Returns to Action Sunday
Alvin Kamara

Ruled Out With Knee Injury
Elias Lindholm

Activated From Injured Reserve
Mikko Rantanen

Suspended for One Game
Amon-Ra St. Brown

Totals Season-High in Yardage in Week 12
Neal Pionk

Sustains Lower-Body Injury Sunday
Donovan Clingan

Upgraded to Available vs. Thunder
Jean-Gabriel Pageau

Out Week-to-Week
Hunter Henry

Feasts in Win Over Cincinnati
Robert Williams III

Sidelined Against Thunder
Anthony Black

Entering the Starting Lineup Versus Boston
Alexander Romanov

Out 5-6 Months Due to Shoulder Surgery
Emanuel Wilson

Punches in Two Touchdowns Against Minnesota
Goga Bitadze

Getting the Start on Sunday Night
Alvin Kamara

Injures Knee Sunday, Questionable to Return
Bogdan Bogdanović

Bogdan Bogdanovic Remains Out Sunday
Ryan Kalkbrenner

Sidelined on Sunday Evening
Tre Mann

Returns to Action Sunday
Wendell Carter Jr.

Ruled Out on Sunday Night
Luke Kennard

Misses Sunday's Contest
Onyeka Okongwu

Good to Go Sunday
Collin Murray-Boyles

Available Against Nets
Egor Demin

Cleared for Sunday
Nicolas Claxton

Available Sunday
Kevin Durant

Will Miss the Next Two Games
Kristaps Porzingis

Taking the Night off on Sunday
Kawhi Leonard

Off the Injury Report, Cleared to Suit Up on Sunday
Sidney Crosby

Records 500th Multi-Point Game
Mackenzie Blackwood

Posts 35-Save Shutout
Aaron Ekblad

Battling an Illness
Jake McCabe

Suffers Upper-Body Injury
Brayden Point

Makes Early Exit Versus Capitals
Nikita Kucherov

Hurt on Saturday
Nic Dowd

Out Against Lightning
Jake Evans

Good to Go Saturday
Gavin Brindley

to Sit Out at Least Two Games
Thomas Chabot

Available Against Sharks
Roman Josi

Returns From 12-Game Absence
Jake Walman

Out Saturday
J.T. Miller

Won't Play Against Mammoth
Gabriel Vilardi

Has Two Goals in Losing Effort
Adolis García

Rangers Non-Tender Adolis Garcia on Friday
CFB

Beau Pribula Expected to Start Against Oklahoma
Dan Hooker

An Underdog At UFC Qatar
Arman Tsarukyan

Looks To Extend His Win Streak
Ian Machado Garry

A Favorite At UFC Qatar
Belal Muhammad

Looks To Bounce Back
Alonzo Menifield

Looks For His Third Consecutive Win
Volkan Oezdemir

Looks To Get Back In The Win Column
Myktybek Orolbai

Looks To Win Back-To-Back Fights
Jack Hermansson

Makes His Welterweight Debut
Kyoji Horiguchi

Returns To The UFC
Elly De La Cruz

Played Through Partially Torn Quad to End 2025
Tarik Skubal

Tigers "Doubtful" to Trade Tarik Skubal
Raisel Iglesias

Returning to the Braves on One-Year Deal
Sahith Theegala

Looking to Continue Fall Run at RSM Classic
Stephan Jaeger

Looking to Bounce Back at RSM Classic
Tom Hoge

Looking to Regain Form at RSM Classic
Joe Highsmith

Searching for Turnaround at RSM Classic
Adam Hadwin

Looking to Build on T11 Finish in Bermuda
Austin Eckroat

Searching for Momentum at RSM Classic
Joel Dahmen

Trying to Find Form at the RSM Classic
CFB

Garrett Nussmeier Doubtful to Play Against Western Kentucky
Michael Thorbjornsen

Hopes to End 2025 Campaign With Another Solid Finish
Andrew Novak

Looks to End 2025 Season on High Note at RSM Classic
Harry Higgs

Teetering for PGA Tour Card in 2026
PGA

Nico Echavarria has the Potential to Contend at the RSM Classic
Sam Stevens

Finishing Out Year in Georgia
Seamus Power

Playing Better at the Right Time
Beau Hossler

Roller Coaster Comes to Saint Simons Island
Quade Cummins

The Time is Now for Quade Cummins in Georgia
Austin Cook

Needs a Win at the RSM Classic
Cameron Champ

on the PGA Tour Card Bubble
Grayson Rodriguez

Shipped to Angels
Taylor Ward

Orioles Acquire Taylor Ward From Angels
Shota Imanaga

Accepts Cubs Qualifying Offer
Brandon Woodruff

Returning to Milwaukee in 2026
Denny McCarthy

Looking For Another Solid Finish at RSM Classic
Si Woo Kim

Looking To Use Current Momentum to Flip Script at RSM Classic
Mackenzie Hughes

a Good Bounce-Back Candidate at RSM Classic
Harris English

Making 14th Start at This Week's RSM Classic
Konnor Griffin

Could Compete for Starting Shortstop Job in 2026
Gleyber Torres

Accepts Tigers Qualifying Offer
CFB

Sam Leavitt Set to Enter Transfer Portal?

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP