🦃 BLACK FRIDAY - TAP TO SAVE 50% WITH CODE THANKS
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

Will James Cook Play Tonight? Fantasy Football Injury Update For 'Monday Night Football'

James Cook - Fantasy Football Rankings, Draft Sleepers, NFL Injury News

Is James Cook playing on "Monday Night Football" or is he out? Is Cook injured or healthy for Week 6 MNF? John Johnson analyzes the latest injury news.

Buffalo Bills running back James Cook is having a fantastic season. He's a near-lock to score double-digit fantasy points when he plays a full game, and he's averaged a touchdown for every game he's played so far. He's the engine of his offense and has the trust of his quarterback and the offensive staff.

He has an excellent role and is the primary running back for all situations. The other running backs seem to come in just to give him a break a few times a game, which is normal for most players. He dominates the snaps and opportunities at his position and there's little threat that he will lose his prominent position in the offense.

However, he's listed on the team's injury report ahead of Week 6. So will James Cook play tonight and is he healthy?

Be sure to check all of our fantasy football rankings for 2025:

 

James Cook Fantasy Football Injury Update

UPDATE: Cook has been ruled OUT

Cook is currently suffering from a toe injury he picked up in Week 5 when his foot slammed onto the turf after he was tackled by a Houston Texans defender, but reports state he is likely good to go. He missed practice altogether on Thursday and Friday but upgraded to a limited participant on Saturday, which is a good sign.

Cook has stated that he plans to play Monday when the Bills take on the New York Jets on the road. It's unknown the exact severity of his injury or whether he'll be load-managed this game, and it's not completely clear if he will play, as he's listed as "questionable" on the injury report. He's reportedly trending upwards, though.

Fantasy managers will likely need to check for updates leading up to the game, and the final list of active players will tell us whether he will be held out or not.

 

James Cook Fantasy Football Injury Impact

He could see a limited workload due to his injury, but he's played far better than the other players he shares the running back room with, so he may not be restricted much. Toe injuries are tricky, and fantasy managers aren't working with much information here. He's still worth starting due to his upside.

Cook's fantasy managers should consider picking up backup Ray Davis. If the lead back ends up being inactive, the rookie will likely carry most of the load. It's a tough matchup against a stingy Jets defense, but there aren't many other options since it's Monday, and all games but one have already been played.

Whichever running back ends up starting for Buffalo is worth a start in most fantasy leagues this week.



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Fantasy Football Analysis

POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Jarrett Allen

Nearing Return From Finger Injury
Andrew Nembhard

Questionable Entering Friday's Contest
Jaden Ivey

Status Uncertain for Friday
Giannis Antetokounmpo

Could Miss Fifth Consecutive Game
Coby White

Questionable for Friday's Matchup
Nikola Vučević

Nikola Vucevic Questionable With Knee Issue Ahead Of Friday
Jameson Williams

Explodes for 144 Yards, Touchdown on Thanksgiving
Dontayvion Wicks

Breaks Out for Two Touchdowns on Thanksgiving
Jordan Love

Lights Up Lions for Four Touchdowns on Thanksgiving
Stephen Curry

Expected To Miss About A Week With Quad Injury
Michael Porter Jr.

Won't Play Friday Versus 76ers
Paul George

Faces Game-Time Call Against Nets
VJ Edgecombe

Sidelined Again Against Nets
Joel Embiid

Out Again Friday vs. Nets
Paolo Banchero

Ruled Out Again Friday With Groin Injury
Jalen Williams

Set to Make Season Debut Friday
Chris Olave

Misses Thursday's Practice
Amon-Ra St. Brown

Will Miss 1-2 Weeks
DeVonta Smith

Off the Injury Report, Cleared for Friday's Game vs. the Bears
Jaxson Dart

Clears Concussion Protocol, Set to Return vs. the Patriots
Amon-Ra St. Brown

Downgraded to Out, Won't Return on Thursday
Daniel Jones

Dealing With Fractured Fibula, Will Play Through it
Jonathan Kuminga

Hoping to Return on Saturday Versus Pelicans
Stephen Curry

to Undergo an MRI
Josh Jacobs

Feels Close to 100%
Brady Tkachuk

Aims to Return Friday
Matthew Tkachuk

Resumes Skating
Jakob Chychrun

Stretches Point Streak to Nine Games
Matej Blumel

Expected to Miss Some Time
Marcus Foligno

Exits With Injury Wednesday
Jaden Schwartz

Suffers Lower-Body Injury Wednesday
Trendon Watford

to Sit Out at Least Two Weeks
Gradey Dick

Injured on Wednesday
RJ Barrett

to Be Re-Evaluated in One Week
Anthony Davis

on the Cusp of Returning
Gary Payton II

Hurt in Wednesday's Loss
Stephen Curry

Diagnosed With Quadriceps Contusion
Alvin Kamara

Doesn't Practice on Wednesday
Lukas Dostal

Out Wednesday Night
Sean Durzi

Available Against Canadiens
Thomas Chabot

to Remain Out Wednesday
Jared McCann

Expected to Rejoin Kraken Lineup Wednesday
Andre Burakovsky

a Game-Time Decision Wednesday
Mikko Rantanen

Returns to Stars Lineup Wednesday
J.K. Dobbins

Could Return Later This Season
Mark Stone

Ready to Return Wednesday
Dylan Cease

Agrees With Blue Jays on Seven-Year, $210 Million Deal
Terry McLaurin

Plans to Play on Sunday Night
Anthony Rendon

Angels Could Buy Out Final Year of Anthony Rendon's Contract
Brandon Aiyuk

49ers Won't Open Brandon Aiyuk's Practice Window This Week
Joe Burrow

Bengals Officially Activate Joe Burrow for a Return on Thanksgiving
C.J. Stroud

Practicing Wednesday
Trey Benson

Spotted at Practice on Wednesday
Marvin Harrison Jr.

Back at Practice Wednesday
DeVonta Smith

Missing From Practice Again on Wednesday
Josh Hader

Says his Shoulder is "Back to Normal"
Ketel Marte

Diamondbacks "Actively Listening" on Ketel Marte
Jaxson Dart

to be a Full Participant at Wednesday's Practice
Dalton Kincaid

has "a Chance" to Play in Week 13
Josh Norris

Nearing Return
Kevin Lankinen

Not Traveling With Canucks
Zach Werenski

Escapes Serious Injury, May Play Wednesday
Auston Matthews

Could Be an Option Wednesday
Jason Robertson

Scores in Seventh Consecutive Game
Wyatt Johnston

Ends Dry Spell With Four-Point Performance
Vinnie Hinostroza

to Miss 4-6 Weeks
Pyotr Kochetkov

Dealing With Undisclosed Injury
J.T. Realmuto

Red Sox Showing Interest in J.T. Realmuto
Sonny Gray

Red Sox Acquire Sonny Gray From the Cardinals
CFB

Jeremiah Smith, Makai Lemon, Skyler Bell Named Biletnikoff Award Finalists
Shohei Ohtani

to Play for Team Japan in 2026 World Baseball Classic
Colorado Rockies

Warren Schaeffer to Stick Around as Rockies Manager in 2026
CFB

Chris Bell Out for Rivalry Matchup Against Kentucky
Ryan Helsley

Tigers Eyeing Ryan Helsley as a Starter
Dan Hooker

Suffers Second-Round Submission Loss
Marcus Semien

Shipped to the Mets on Sunday
Arman Tsarukyan

Gets Submission Win
Brandon Nimmo

Traded to Texas
Belal Muhammad

Loses Back-to-Back Fights
Belal Muhammad

Ian Machado Garry Outpoints Belal Muhammad
Alonzo Menifield

Suffers First-Round Knockout Loss
Volkan Oezdemir

Gets Back In The Win Column
Jack Hermansson

Gets Knocked Out
Jack Hermansson

Myktybek Orolbai Knocks Out Jack Hermansson
Shamil Gaziev

Suffers First-Round Knockout Loss
Waldo Cortes-Acosta

Shines At UFC Qatar
Tagir Ulanbekov

Suffers Third-Round Submission Loss
Kyoji Horiguchi

Makes Triumphant UFC Return

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP