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Who Is the #1 Pick in 2021 Fantasy Football?

Chris Mangano determines which players to target as the #1 overall pick in 2021 fantasy football drafts.

The 2020 fantasy football season may be over, but it’s never too early to look ahead. The draft season for 2021 will be here before you know it, and one of the biggest questions will be who should be the number one pick?

Here are my top-five choices (in order) and why they should or should not be the number one overall pick.

Note: I originally published this early in the offseason. Now that we are closer to fantasy drafts, let's see what has changed and if there is a new number 1...

Be sure to check all of our fantasy football rankings for 2025:

 

5. Davante Adams (WR, GB)

Adams was unquestionably the best wide receiver in football, both real life and fantasy. If not for missing two games, he realistically could have been the number one overall scorer. Adams finished with 109 receptions (third), 1,328 yards (fourth), and 17 touchdowns (first). Had he not missed two games, he likely would have finished first in each category. In terms of fantasy football (PPR scoring), he finished number two overall and was only 36 points away from number one overall, Alvin Kamara.

With Aaron Rodgers back for at least one more season, Adams has a legitimate case for the number one overall pick. But outside of leagues that strongly favor wide receivers, it is hard to put him ahead of the stud running backs. Still, he should absolutely be the first wide receiver off the board in 2021 fantasy football drafts.

 

4. Travis Kelce (TE, KC)

Outside of Alvin Kamara (more on him later) and Davante Adams, Kelce was the unquestioned MVP of most fantasy leagues. He dominated a position that had few start-able options week to week, let alone dominant options. Kelce outscored TE2, Darren Waller, by a massive 60.9 fantasy points in 2020. He scored 20 or more fantasy points in 10 games, and when it mattered most he dominated with games of 27.6, 22.8 and 22.8 in the fantasy playoffs.

In shallow leagues (10 or 12 team leagues with relatively few starters) you can make the case that he gives you the biggest advantage of any player at any position. However, in deeper formats (12+ leagues with more starting options) it becomes tougher to draft Kelce and still field a dominant roster. Regardless, Kelce has to be considered a first rounder in all formats and is head and shoulders above the other tight ends but taking him number one overall seems like a stretch.

 

3. Alvin Kamara (RB, NO)

Alvin Kamara literally won people their fantasy championship in 2020. He was the number one non-quarterback scorer, and only Kyler Murray, Josh Allen, and Patrick Mahomes scored more points than him. He played every game, and oh, he literally won people's fantasy titles with his incredible six-touchdown performance in Week 16. So why isn’t he number one? Simply put, we don’t know who will be the Saints quarterback in 2021.

Despite him setting career highs in rushing yards and rushing touchdowns in Week 16, Kamara’s value comes from his work in the passing game. We saw what happened when Taysom Hill replaced Drew Brees; Kamara was solid, but he certainly wasn’t worthy of the number one overall pick in those games. With Drew Brees officially retired, and the Saints quarterback situation looking like it will come down to the wire, it's hard to take Kamara number one overall. Still, he is firmly in the top-3, just don't expect a repeat of 2020.

 

2. Dalvin Cook (RB, MIN)

When drafting a top fantasy football pick, you really want two things: to avoid a season-ending injury and to avoid a bust. While Cook has had injury concerns in the past (which running back outside of Kamara hasn’t?), you know exactly what you are getting with him every week. The Vikings under head coach Mike Zimmer are a run-first team, as they ran the ball at the sixth-highest rate in 2020 and the fourth highest in 2019.

Cook had 312 carries in 2020 (second), 1,557 rushing yards (second), and 16 rushing touchdowns (first). He also chipped in 44 receptions and another 361 receiving yards. He did all that in just 15 games. That kind of usage gives him one of the safest floors and highest ceilings in all of fantasy. He would easily be my overall number one if not for…

 

1. Christian McCaffrey (RB, CAR)

Don’t let his injury-plagued 2020 scare you off of him. In the three healthy games McCaffrey played this year, he handled over 90% of the running back touches for Carolina. He is a true workhorse back in the NFL. In PPR formats, he scored 28.5, 24.8, and 37.1 points in those three games, averaging over 30 points per game. He averaged just under 20 carries per game and over six receptions per game. Not to mention he scored six touchdowns.

He has the highest floor and the highest ceiling in all of fantasy football. Prior to 2020, he had also been one of the most durable players, having never missed a game in his three-year career or throughout his entire college career. Don’t let one season of bad injury luck prevent you from drafting unquestionably the best player in fantasy football. McCaffrey should be the number one pick in every draft next year. 

So there you have it, my top-five and number one overall picks for 2021 fantasy football drafts. Do you agree or disagree? Let me know in the comments. 



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Check out all of RotoBaller's fantasy football rankings. Staff rankings are updated regularly for all positions and include standard formats, PPR scoring, tiered rankings and dynasty leagues.




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REAL-TIME FANTASY NEWS

Maxx Crosby

Trending Toward Playing Against Broncos
Chris Olave

Set to Play Vs. Bucs
LaMelo Ball

Won't Suit Up Against Denver
Immanuel Quickley

Questionable for Sunday Afternoon
Deshaun Watson

Expected to Stay With Browns Next Year
Klay Thompson

Downgraded Versus Houston
Alperen Sengün

Alperen Sengun Out Again on Saturday Evening
Tyler Herro

Will Miss Another Game on Saturday
Jimmy Butler III

Out Again on Saturday Night
Draymond Green

Ruled Out Versus Cleveland
Jose A. Ferrer

Mariners Acquire Jose A. Ferrer from the Nationals
Mason Marchment

Expected to Return Saturday
Danila Yurov

Returns From Two-Game Absence Saturday
Jesperi Kotkaniemi

Available Saturday
Harry Ford

Traded to the Nationals
Shane Pinto

to Miss Two Weeks
David Pastrnak

Misses Fifth Consecutive Game Saturday
Andrei Vasilevskiy

Remains Out Saturday
Nikita Kucherov

Out on Saturday
Jayden Reed

Activated Off Injured Reserve, Will Play in Week 14
Omarion Hampton

Activated From IR, Faces Uncertain Workload Monday Night
Cody Bellinger

Drawing Interest From the Phillies
MacKenzie Gore

Will the Nationals Trade MacKenzie Gore?
Justin Herbert

Officially Listed as Questionable for Monday Night Football
Justin Herbert

Chargers "Expecting" Justin Herbert to Play in Week 14
Yves Missi

Trending Toward Game-Time Decision
Khris Middleton

Questionable With Knee Soreness Against Hawks
Noah Clowney

On Track To Suit Up Against Pelicans
De'Anthony Melton

Questionable With Knee Management
Draymond Green

Questionable With Mid-Foot Sprain
Jimmy Butler III

Day-To-Day As Warriors Prepare For Cleveland
Mikko Rantanen

Picks Up Three Points Against Sharks
Kyle Connor

Scores in Fourth Consecutive Game
Beckett Sennecke

Notches Two Points in Friday's Win
Ryan Leonard

Suffers Upper-Body Injury Friday
Carter Hart

Day-to-Day With Lower-Body Injury
Brayden Point

Questionable for Saturday
Victor Hedman

Expected to Return Saturday
Byron Buxton

Twins Not Planning to Trade Joe Ryan, Byron Buxton
Patrick Williams

Dalen Terry Available Versus Pacers
Coby White

Returns With Minutes Restriction Friday
Ayo Dosunmu

Out Friday Against Pacers
Zach Collins

Available for Season Debut Friday
Robert Williams III

Donovan Clingan Out, Robert Williams III in for Portland Friday
Evan Mobley

Ready to Play Friday
Kristaps Porzingis

Coming Off the Bench Friday
Spencer Jones

Available Against Hawks
Ozzy Wiesblatt

to Miss 8-10 Weeks With Upper-Body Injury
Pierre-Olivier Joseph

Out With Illness Friday
Evander Kane

Doubtful for Friday
Conor Garland

Back From Two-Game Absence Friday
Thomas Harley

Could Be an Option Next Week
Mikael Granlund

Returning From 10-Game Absence Friday
John Carlson

Misses Second Consecutive Game Friday
Rome Odunze

has Fractured Foot, Labeled Week-to-Week
Sauce Gardner

Ruled Out for Sunday
Petr Yan

Looks To Reclaim Bantamweight Belt
Merab Dvalishvili

Set For His Fourth Title Defense
Joshua Van

Can Become The New Flyweight Champion
Aaron Jones Sr.

Cleared to Play in Week 14
Chris Olave

Listed as Questionable for Week 14
Alexandre Pantoja

Set For Fifth Title Defense At UFC 323
Tatsuro Taira

Looks To Win Back-To-Back Fights
Alvin Kamara

Ruled Out for Sunday
Brandon Moreno

Searches For His Third Win In A Row
Rome Odunze

Ruled Out for Week 14
Payton Talbott

A Favorite At UFC 323
Henry Cejudo

Set For His Retirement Fight
Drake London

Ruled Out vs Seattle
Jan Blachowicz

Set To Open Up UFC 323 Main Card
Lamar Jackson

Will Play on Sunday
Bogdan Guskov

Looks To Extend His Win Streak
CFB

Emmett Johnson Leaving Nebraska for 2026 NFL Draft
Dalton Kincaid

to be Questionable for Week 14
Tee Higgins

Clears Concussion Protocol, is a Full-Go for Sunday
CFB

Jam Miller Unlikely to Play in SEC Title Game
CFB

Penn State Expected to Hire Matt Campbell from Iowa State
Mike Evans

Not Quite Ready to Return This Week
Jayden Daniels

Will Start Against Vikings
Lamar Jackson

Returns to Practice, on Track to Play on Sunday
Kyler Murray

Won't Return This Year, Cardinals Non-Committal on his Future
CFB

Arkansas Targeting Ron Roberts for Defensive Coordinator Job
Jhostynxon Garcia

Pirates Acquire Jhostynxon Garcia From Red Sox
Cody Bellinger

Yankees Pushing Hard to Re-Sign Cody Bellinger
CFB

Penn State Eyeing Iowa State Coach Matt Campbell For Coaching Vacancy
Alex Bregman

Cubs Have Renewed Interest in Alex Bregman
CFB

Billy Napier Finalizing Deal to Become James Madison's New Head Coach
CFB

Buster Faulkner Set to Become Florida's New Offensive Coordinator
CFB

Joe Sloan Expected to be Kentucky's New Offensive Coordinator
CFB

Lane Kiffin Working to Keep Defensive Coordinator Blake Baker at LSU
CFB

Brian Daboll a Candidate for Penn State Head-Coaching Job?
Kyle Tucker

Visits With Blue Jays
Emilio Pagán

Reds Bring Back Closer Emilio Pagan on Two-Year Deal
Cedric Mullins

Rays Agree on One-Year Deal
Freddy Peralta

Brewers Considering Trading Freddy Peralta
Kyle Schwarber

Reds Serious About Adding Kyle Schwarber in Free Agency?
CFB

Brent Key Signing Five-Year Deal to Remain at Georgia Tech
CFB

Brian Hartline Expected to Land USF Head-Coaching Job
CFB

Collin Klein Expected to be Top Target for Kansas State if Head-Coach Job Opens
CFB

Chris Klieman Considering Stepping Down at Kansas State
CFB

D.J. Durkin Staying at Auburn Under Alex Golesh
CFB

Charlie Weis Jr. Permitted to Coach Ole Miss Offense in College Football Playoff
CFB

Five-Star Quarterback Jared Curtis Flips Commitment From Georgia to Vanderbilt
CFB

Florida Hiring Brad White as Defensive Coordinator
Kyle Schwarber

Giants Have Checked in on Kyle Schwarber
Willson Contreras

Willing to Waive his Full No-Trade Clause?
Edwin Díaz

Mets Still Interested in Re-Signing Edwin Diaz
Devin Williams

Agrees to Three-Year Deal With Mets
Cole Ragans

Red Sox Targeting Cole Ragans in a Trade?
CFB

Kentucky Hires Oregon Offensive Coordinator Will Stein As Head Coach
CFB

Kalani Sitake the Top Target for Penn State Coaching Job
CFB

Josh Heupel Says He's Not a Candidate for Penn State Head Coach Job

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