👉 TAP TO SAVE 30% WITH CODE NEW
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

TNF NFL DFS Lineup Picks for FanDuel, DraftKings - 49ers vs Titans Showdown

John's top NFL DFS lineup picks for FanDuel, DraftKings and Thursday Night Football - the 49ers vs Titans showdown slate. His Week 16 TNF daily fantasy football advice.

Happy Thursday, RotoBallers! Week 16 is here! This season has been going by super quickly, and I can't believe that this is the last Thursday Night game of the season. We have a rather interesting contest tonight as the 49ers (8-6) head to Nashville to take on the Titans (9-5). This is a battle that should put a dent in the AFC West divisional race regardless of the result, and it should be an exciting one. Thanks to the advanced analytics of today, I'll do my best to provide you with as much in-depth analysis as possible regarding positional matchups and the like to help put some lunch money in your pocket. 

In this article I will be providing you with daily fantasy football picks on FanDuel and DraftKings for the Thursday Night Football slate on December 23rd. These lineups can vary from higher-priced players and elite options to lower-priced players and value picks on both DraftKings and FanDuel.

If you have any questions you can follow me on Twitter @LucidMediaDFS and fire away, or sign up for a premium RotoBaller NFL package and chat with me and other NFL DFS analysts any time you'd like. Let's make some coin this season gang, and let's get right to it!

Featured Promo: Looking for some more fantasy football action? Adopt a dynasty orphan team over at FFPC. Sign up today and get $25 off any FFPC league. Sign Up Now!

 

DFS Captains/MVPs for DraftKings, FanDuel

Ryan Tannehill ($15,000 DK, $15,000 FD)

Key Stats:

  • 2021 Stats: 3,118 passing yards, 14 touchdowns, 14 interceptions. 
  • Offensive Pass DVOA: -2.9% (26th)
  • Opposing Defense Pass DVOA: 7.1% (21st)

Tannehill hasn't necessarily had "the magic" as we saw from him last year, which we can partly blame on the loss of Derrick Henry mid-season. However, Tannehill is still very much "fantasy-viable" if you need a guy who has a solid floor. While his ceiling isn't too high, I can expect Tennessee to throw the ball quite a bit tonight, and getting A.J. Brown back in the lineup should provide the boost that Tannehill needs to have a solid game.

Recommendation: Cash/GPP (DK/FD)

Best Correlations: A.J. Brown, Deebo Samuel

 

Jeff Wilson Jr. ($7,800 DK, $11,000 FD)

Key Stats:

  • 2021 Stats: 65 attempts, 249 yards, one touchdown, five targets, four receptions, 19 yards. 
  • 2021 Data: 31.71% attempt rate, 30.43% red-zone attempt rate, 33.33% rate within the 5yd line, 3.68% target rate, 9.09% red-zone target rate, one end zone target.
  • Offensive Rush DVOA: 7.1% (4th)
  • Opposing Defense Rush DVOA: -9.5% (17th)

Jeff Wilson Jr. finally broke out last week to the cheers of DFS players everywhere. If I had to guess, he'll be one of if not the most expensive captains on the slate on DraftKings. His price is too cheap and he does have a solid matchup against a middle-of-the-road rushing defense. While I do have some concerns over Deebo Samuel taking 14 carries over the last two weeks, I would expect Kyle Shanahan to stick to his game plan of running the football so Wilson getting 10-12 touches seems inevitable. This creates a solid value opportunity, especially on DK, for Wilson to be in your captain spot.

Recommendation: Cash/GPP (FD/DK)

Best Correlations: Ryan Tannehill, George Kittle

Other Captain/MVP Plays: Deebo Samuel, A.J. Brown

 

DFS Flex Plays for DraftKings, FanDuel

Jimmy Garoppolo ($10,400 DK, $14,000 FD)

Key Stats:

  • 2021 Stats: 3,172 passing yards, 18 touchdowns, 8 interceptions.
  • Offensive Pass DVOA: 33.2% (4th)
  • Opposing Defense Pass DVOA: 4.8% (15th)

Every time I look at this year's DVOA and see the 49ers sitting at fourth it surprises me. All credit to them, but I certainly wouldn't rate them as the fourth-best passing offense in football. Regardless, Jimmy G has been throwing the pill around well of late. I don't really like going double QB on DraftKings and I prefer Tannehill to Garoppolo, but I will most likely be running Jimmy G in most of my FanDuel lineups.

Recommendation: Cash/GPP (FD/DK)

Best Correlations: George Kittle, Deebo Samuel, Ryan Tannehill

 

George Kittle ($11,200 DK, $13,000 FD)

Key Stats:

  • 2021 Stats: 82 targets, 63 receptions, 850 receiving yards, six touchdowns.
  • 2021 Data: 25.31% target rate, 17.95% red-zone target rate, five end zone targets.  
  • Individual Matchup (vs Jayon Brown): 11% target per route covered, 88% catch rate, 0.23 fantasy points per route. 

While to some there was never a doubt regarding Kittle's quality as a tight end, Kittle has certainly silenced any and all doubters over the last three weeks. He's logged 28 catches for 425 yards and three touchdowns in that span and has a very intriguing matchup against the Titans' defense (and Jayon Brown specifically) tonight. His price is steep, but for a guy who's been consistently putting up numbers of late, I want him in my lineups. I should note that I prefer him slightly over Deebo Samuel tonight but should have plenty of them both.

Recommendation: GPP (DK), Cash/GPP (FD)

Best Correlations: Jimmy Garoppolo, Ryan Tannehill

Other Flex Plays: A.J. Brown, Julio Jones, D'Onta Foreman

 

DFS Value Plays for DraftKings, FanDuel

49ers D/ST ($3,800 DK)

Key Stats:

  • 2021 Stats: 6 interceptions, 11 fumble recoveries, 36 sacks, two defensive touchdowns. 

There is a chance tonight that even with the return of A.J. Brown, the Titans' offense stalls and can't really get anything going tonight against a relatively hot SF defense. I'll most likely be using them in stacks with Jeff Wilson Jr. as well as some San Francisco onslaught stacks, but backing the Niners here is a solid way to create some space if you want both Kittle and Deebo in your lineups.

Recommendation: Cash/GPP (FD/DK)

Best Correlations: Jimmy Garopollo, Jeff Wilson Jr.

Robbie Gould ($4,400 DK, $9,000 FD)

While he hasn't been "as good as Gould" this season, he's still been pretty dang solid. He's knocked down 14 of 17 field goals and has missed just one extra point all season. He's logged at least seven fantasy points in each of the last four games, and that should continue tonight. I feel that regardless of how the game script goes, Gould should be optimal. Remember: kickers are always optimal.

Recommendation: Cash/GPP (FD/DK)

Best Correlations: Jimmy Garoppolo, Jeff Wilson Jr.

Other Value Plays: Nick Westbrook-Ikhine, Anthony Firkser

 

Overall Slate Note

This should be a fun slate with two offenses that seem rather consolidated and want their big boys to do most of the work for them. I'll have a ton of ownership among both teams' top skill-position guys, and just slightly more Tannehill than Jimmy G on both sites in tournaments. I don't have much to say as far as lineup restrictions go, other than the suggestion of not playing both Foreman and Hilliard in the same lineups. Outside of that, I'd like to thank you for reading my Thursday Night articles in this goofy but fun 2021 season. I also want to wish you a Merry Christmas, Happy Holidays, and wish you health and happiness for the rest of 2021 and throughout 2022. I'll catch you all on Sunday!

Have a good Thursday everyone, see you soon!



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Weekly DFS Analysis




POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Rudy Gobert

to Rest on Friday
Tari Eason

is Cleared to Play on Thursday
Kobe Brown

Won't Play on Thursday
Ben Sheppard

to Miss Third Straight Game
Jarace Walker

is Available on Thursday
Sam Hauser

Available Against Knicks
Collin Sexton

Active Against Wizards
Neemias Queta

Good to Go on Thursday
Derrick White

Cleared to Suit Up Against Knicks
Blake Coleman

Unavailable Thursday
Stephen Curry

Ruled Out Against Lakers on Thursday
Quinton Byfield

Cleared to Play Thursday
Thomas Chabot

Makes Surprise Return Thursday
Jaylen Brown

Out Thursday
Luke Hughes

to Miss Rest of Season
Stuart Skinner

Faces Devils Thursday
Joel Embiid

Undergoes Surgery for Appendicitis
Nazem Kadri

to "Miss Some Games" With Finger Injury
Seth Jones

to Miss Rest of Season Due to Broken Foot
Corbin Carroll

Dealing With Hip Injury, Not Expected to Miss Much Time
NFL

Jordyn Tyson to Hold Individual Workout on April 17
Brent Rooker

Exits Early on Thursday Due to Apparent Injury
NFL

No New Injury Issues for Francis Mauigoa
Travis Hunter

to be "Limited Participant" During Offseason Workouts
Carolina Panthers

Denzel Boston Visiting With Panthers on Thursday
Mark Andrews

Ready for More Opportunities in 2026
Tyrone Tracy Jr.

Part of a Muddled Giants Backfield Heading into 2026
Chimere Dike

Fantasy Value Potentially Limited by What He Offers in Return Game
Chase Brown

an Important Name to Monitor on Day 1 of the NFL Draft
Bijan Robinson

Could Just Be Entering His Prime
Jameson Williams

Consistency the Key to a True Jameson Williams Breakout
Jarace Walker

May Exit Pacers Lineup Again Thursday
Aaron Nesmith

Out for Sixth Consecutive Game
T.J. McConnell

Andrew Nembhard, T.J. McConnell Unavailable Thursday
Dru Smith

Iffy for Thursday
Norman Powell

Questionable Thursday
Sam Hauser

Could Miss Thursday's Game
Neemias Queta

Uncertain for Thursday
Zach Benson

Scores Twice in Comeback Victory
Logan Thompson

Shuts Out the Leafs
Zach Eflin

Undergoes Successful Elbow Surgery, Will Miss Remainder of 2026
Derrick White

Listed as Questionable for Thursday
Tre Johnson

Iffy for Thursday
J.K. Dobbins

Broncos Prioritized Re-Signing J.K. Dobbins
NFL

Francis Mauigoa to Undergo Additional Imaging on a Back Issue
Kaleb McGary

Retires After Seven Years in the NFL
Jawaan Taylor

Signs with the Falcons
Andrei Kuzmenko

to Be Re-Evaluated in 7-8 Days
Mason Appleton

Won't Play Thursday
Tony DeAngelo

Expected to Return Thursday
John Klingberg

Rejoins Sharks Lineup Wednesday
Alex Lyon

Dealing With Lower-Body Injury
Oliver Ekman-Larsson

Back in Action Wednesday
Alex Ovechkin

Won't Decide Future Until Offseason
Cole Ragans

"Should be Good" for Next Start
Reynaldo López

Reynaldo Lopez Handed Seven-Game Suspension
Jorge Soler

Suspended Seven Games, Will Appeal
NFL

NFL Scouts See Plenty of Upside With Drew Allar
NFL

Ty Simpson to Fall into Second Round in NFL Draft?
Cleveland Browns

Todd Monken "Fired Up" About Quarterback Competition
Cleveland Browns

KC Concepcion Visiting With the Browns
Cole Ragans

Diagnosed With Thumb Contusion
Houston Texans

Texans Pick Up Will Anderson's Fifth-Year Option
C.J. Stroud

Texans Exercise C.J. Stroud's Fifth-Year Option
Cole Ragans

Leaves Early on Wednesday After Being Hit in the Hand
Jacob deGrom

Expects to Make his Next Start
Konnor Griffin

Pirates Sign Konnor Griffin to Nine-Year Extension
Parker Washington

Undervalued Despite League-Winning Finish in 2025
Justus Annunen

Ends Predators' 120-Game Streak Without a Shutout
Trevor Zegras

Leads Flyers to Victory Tuesday
Kevin Bahl

Sustains Lower-Body Injury Against Stars
Michael Rasmussen

Likely to Miss Rest of Regular Season
Dmitry Kulikov

Done for the Season After Breaking Finger
Tyrrell Hatton

a Steady Option at The Masters
Justin Thomas

a High-Risk, High-Reward Option at The Masters
PGA

Sungjae Im a Volatile Option at the Masters
Nicolai Hojgaard

Carrying Momentum Into The Masters
Si Woo Kim

in Strong Form Heading to The Masters
Chris Gotterup

Ready to Make His Masters Debut
Patrick Reed

Brings Momentum to The Masters
Jon Rahm

Looks Poised for His Second Green Jacket
Jacob deGrom

Doesn't Have Structural Damage in his Knee
J.T. Realmuto

Leaves Game on Tuesday Due to Bruised Right Foot
Cody Ponce

to Have Knee Surgery, Expected to Miss Six Months
Alejandro Kirk

Facing Six-Week Absence
Jacob deGrom

to Undergo MRI on Tuesday
Mike Trout

Back in the Lineup on Tuesday
Hunter Brown

Diagnosed with Grade 2 Shoulder Strain
Adam Scott

Form Points to Him Competing at Masters
Jordan Spieth

Finding Consistency Heading to Masters
Hideki Matsuyama

Trending In Right Direction For Masters
Cade Horton

to Undergo Season-Ending Elbow Surgery
Tommy Fleetwood

a Contender if his Putter Cooperates at The Masters
Jacob deGrom

Pitches Through Knee Issue on Monday
Dalton Rushing

Smacks Two Homers in Rout of Blue Jays
Max Scherzer

Dealing With Forearm Tendinitis, Expected to Make his Next Start
Collin Morikawa

Vegas has Lost Confidence in Collin Morikawa Ahead of Masters Tournament
Ludvig Aberg

One of the Top Plays For This Week's Masters Tournament
Rory McIlroy

Set to Defend his Long-Awaited Masters Victory
Bryson DeChambeau

Looks to Finally Claim a Green Jacket
Patrick Cantlay

Needs Plenty to Go Right at Augusta
Harris English

Playing Solid Golf Heading to Masters
Sam Burns

Bouncing Back Nicely After Slow Start to 2026 Season
Corey Conners

Quietly Putting Together A Strong 2026 Season
Russell Henley

Looks to Bounce Back At Masters
Chris Duncan

Suffers Second-Round Submission Loss
Renato Moicano

Gets Back In The Win Column
Tabatha Ricci

Gets Outgrappled
Virna Jandiroba

Bounces Back
Brendson Ribeiro

Suffers First-Round Submission Loss
Abdul-Rakhman Yakhyaev

Earns First-Round Submission Win
Rafael Estevam

Suffers His First Loss
Ethyn Ewing

Dominates At UFC Vegas 115
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF