👉 TAP TO SAVE 50% WITH CODE SPRING
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Draft Rankings
Draft Simulator
Compare Any Players
24x7 News and Alerts

TNF NFL DFS Lineup Picks for FanDuel, DraftKings - 49ers vs Titans Showdown

John's top NFL DFS lineup picks for FanDuel, DraftKings and Thursday Night Football - the 49ers vs Titans showdown slate. His Week 16 TNF daily fantasy football advice.

Happy Thursday, RotoBallers! Week 16 is here! This season has been going by super quickly, and I can't believe that this is the last Thursday Night game of the season. We have a rather interesting contest tonight as the 49ers (8-6) head to Nashville to take on the Titans (9-5). This is a battle that should put a dent in the AFC West divisional race regardless of the result, and it should be an exciting one. Thanks to the advanced analytics of today, I'll do my best to provide you with as much in-depth analysis as possible regarding positional matchups and the like to help put some lunch money in your pocket. 

In this article I will be providing you with daily fantasy football picks on FanDuel and DraftKings for the Thursday Night Football slate on December 23rd. These lineups can vary from higher-priced players and elite options to lower-priced players and value picks on both DraftKings and FanDuel.

If you have any questions you can follow me on Twitter @LucidMediaDFS and fire away, or sign up for a premium RotoBaller NFL package and chat with me and other NFL DFS analysts any time you'd like. Let's make some coin this season gang, and let's get right to it!

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

DFS Captains/MVPs for DraftKings, FanDuel

Ryan Tannehill ($15,000 DK, $15,000 FD)

Key Stats:

  • 2021 Stats: 3,118 passing yards, 14 touchdowns, 14 interceptions. 
  • Offensive Pass DVOA: -2.9% (26th)
  • Opposing Defense Pass DVOA: 7.1% (21st)

Tannehill hasn't necessarily had "the magic" as we saw from him last year, which we can partly blame on the loss of Derrick Henry mid-season. However, Tannehill is still very much "fantasy-viable" if you need a guy who has a solid floor. While his ceiling isn't too high, I can expect Tennessee to throw the ball quite a bit tonight, and getting A.J. Brown back in the lineup should provide the boost that Tannehill needs to have a solid game.

Recommendation: Cash/GPP (DK/FD)

Best Correlations: A.J. Brown, Deebo Samuel

 

Jeff Wilson Jr. ($7,800 DK, $11,000 FD)

Key Stats:

  • 2021 Stats: 65 attempts, 249 yards, one touchdown, five targets, four receptions, 19 yards. 
  • 2021 Data: 31.71% attempt rate, 30.43% red-zone attempt rate, 33.33% rate within the 5yd line, 3.68% target rate, 9.09% red-zone target rate, one end zone target.
  • Offensive Rush DVOA: 7.1% (4th)
  • Opposing Defense Rush DVOA: -9.5% (17th)

Jeff Wilson Jr. finally broke out last week to the cheers of DFS players everywhere. If I had to guess, he'll be one of if not the most expensive captains on the slate on DraftKings. His price is too cheap and he does have a solid matchup against a middle-of-the-road rushing defense. While I do have some concerns over Deebo Samuel taking 14 carries over the last two weeks, I would expect Kyle Shanahan to stick to his game plan of running the football so Wilson getting 10-12 touches seems inevitable. This creates a solid value opportunity, especially on DK, for Wilson to be in your captain spot.

Recommendation: Cash/GPP (FD/DK)

Best Correlations: Ryan Tannehill, George Kittle

Other Captain/MVP Plays: Deebo Samuel, A.J. Brown

 

DFS Flex Plays for DraftKings, FanDuel

Jimmy Garoppolo ($10,400 DK, $14,000 FD)

Key Stats:

  • 2021 Stats: 3,172 passing yards, 18 touchdowns, 8 interceptions.
  • Offensive Pass DVOA: 33.2% (4th)
  • Opposing Defense Pass DVOA: 4.8% (15th)

Every time I look at this year's DVOA and see the 49ers sitting at fourth it surprises me. All credit to them, but I certainly wouldn't rate them as the fourth-best passing offense in football. Regardless, Jimmy G has been throwing the pill around well of late. I don't really like going double QB on DraftKings and I prefer Tannehill to Garoppolo, but I will most likely be running Jimmy G in most of my FanDuel lineups.

Recommendation: Cash/GPP (FD/DK)

Best Correlations: George Kittle, Deebo Samuel, Ryan Tannehill

 

George Kittle ($11,200 DK, $13,000 FD)

Key Stats:

  • 2021 Stats: 82 targets, 63 receptions, 850 receiving yards, six touchdowns.
  • 2021 Data: 25.31% target rate, 17.95% red-zone target rate, five end zone targets.  
  • Individual Matchup (vs Jayon Brown): 11% target per route covered, 88% catch rate, 0.23 fantasy points per route. 

While to some there was never a doubt regarding Kittle's quality as a tight end, Kittle has certainly silenced any and all doubters over the last three weeks. He's logged 28 catches for 425 yards and three touchdowns in that span and has a very intriguing matchup against the Titans' defense (and Jayon Brown specifically) tonight. His price is steep, but for a guy who's been consistently putting up numbers of late, I want him in my lineups. I should note that I prefer him slightly over Deebo Samuel tonight but should have plenty of them both.

Recommendation: GPP (DK), Cash/GPP (FD)

Best Correlations: Jimmy Garoppolo, Ryan Tannehill

Other Flex Plays: A.J. Brown, Julio Jones, D'Onta Foreman

 

DFS Value Plays for DraftKings, FanDuel

49ers D/ST ($3,800 DK)

Key Stats:

  • 2021 Stats: 6 interceptions, 11 fumble recoveries, 36 sacks, two defensive touchdowns. 

There is a chance tonight that even with the return of A.J. Brown, the Titans' offense stalls and can't really get anything going tonight against a relatively hot SF defense. I'll most likely be using them in stacks with Jeff Wilson Jr. as well as some San Francisco onslaught stacks, but backing the Niners here is a solid way to create some space if you want both Kittle and Deebo in your lineups.

Recommendation: Cash/GPP (FD/DK)

Best Correlations: Jimmy Garopollo, Jeff Wilson Jr.

Robbie Gould ($4,400 DK, $9,000 FD)

While he hasn't been "as good as Gould" this season, he's still been pretty dang solid. He's knocked down 14 of 17 field goals and has missed just one extra point all season. He's logged at least seven fantasy points in each of the last four games, and that should continue tonight. I feel that regardless of how the game script goes, Gould should be optimal. Remember: kickers are always optimal.

Recommendation: Cash/GPP (FD/DK)

Best Correlations: Jimmy Garoppolo, Jeff Wilson Jr.

Other Value Plays: Nick Westbrook-Ikhine, Anthony Firkser

 

Overall Slate Note

This should be a fun slate with two offenses that seem rather consolidated and want their big boys to do most of the work for them. I'll have a ton of ownership among both teams' top skill-position guys, and just slightly more Tannehill than Jimmy G on both sites in tournaments. I don't have much to say as far as lineup restrictions go, other than the suggestion of not playing both Foreman and Hilliard in the same lineups. Outside of that, I'd like to thank you for reading my Thursday Night articles in this goofy but fun 2021 season. I also want to wish you a Merry Christmas, Happy Holidays, and wish you health and happiness for the rest of 2021 and throughout 2022. I'll catch you all on Sunday!

Have a good Thursday everyone, see you soon!



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Weekly DFS Analysis




POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Draft Rankings
Draft Simulator
Compare Any Players
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Ayo Dosunmu

Considered Questionable for Game 3 Against Spurs
Anthony Edwards

Remains Questionable on Injury Report Ahead of Game 3
Mitchell Robinson

Probable for Friday's Action
Kevin Huerter

Remains Out Thursday
Sam Merrill

Unavailable Thursday
OG Anunoby

Tagged as Questionable for Friday
Joel Embiid

Listed as Questionable for Game 3 Against Knicks
Dan Vladar

Looks to Return to Winning Ways Thursday
Connor Dewar

Penguins Re-Sign Connor Dewar for Two Years
Mikko Rantanen

Played Through Torn MCL Late in the Season
Rasmus Dahlin

Ready to Go Friday
Kyle Pitts Sr.

Signs Franchise Tender on Thursday
Alexander Nikishin

Set to Return Thursday
Joe Burrow

Attending Voluntary Workouts, Ready for Monster Season?
Christian Dvorak

Available Thursday
Owen Tippett

Remains Out Thursday
Roman Anthony

Heading for the Injured List
CFB

Sam Leavitt Expected to Be Full-Go for Fall Camp
T.J. Hockenson

Can T.J. Hockenson Bounce Back with Improved Quarterback Play in Minnesota?
Jordan Love

Is Jordan Love's Dynasty Upside Fading Entering 2026?
Dalton Schultz

Facing Increased Playing Time Competition in Houston Entering 2026
Kimani Vidal

Dynasty Value in Question Due to Uncertain Playing Time Outlook
Juwan Johnson

Facing Reduced Role in New Orleans Following NFL Draft?
Chuba Hubbard

a Prime Bounce-Back Candidate Following Offseason Moves
Indianapolis Colts

Kenny Moore Granted his Release by Colts
Minnesota Vikings

Chad Alexander a Candidate for Vikings GM Job
Tarik Skubal

Could Return in 4-6 Weeks After Successful Elbow Surgery
Minnesota Vikings

Vikings Request to Interview RJ Gillen for GM Job
Drake Maye

Shoulder Doing "Great"
Gunnar Helm

a Clear Breakout Candidate Despite Crowded Offense?
Travis Hunter

Dynasty Managers Regret Drafting Travis Hunter?
Khalil Shakir

Offseason Addition a Threat to Khalil Shakir's Consistency?
Christian Watson

Can Christian Watson Overcome Injury History?
Pat Freiermuth

a Bounce-Back Candidate in New System
Tua Tagovailoa

Lacks Long-Term Appeal in Dynasty Leagues
Cole Ragans

Royals Hopeful That Cole Ragans Makes his Next Start
Jordan Mason

Still Holding Dynasty Value
Aaron Rodgers

Planning a Visit With Steelers
Dontayvion Wicks

What is Dontayvion Wicks' Dynasty Ceiling?
Paul George

Does a Little Bit of Everything in Game 2 Loss
Tyrese Maxey

Tallies Team-High 26 Points in Wednesday's Loss
Jalen Brunson

Leads Knicks With 26 Points Wednesday
Victor Wembanyama

Notches Another Double-Double
Stephon Castle

Scores Game-High 21 Points in Blowout Win
Ayo Dosunmu

Exits Game 2 With Heel Issue
OG Anunoby

Suffers Apparent Leg Injury Wednesday
Mark Stone

Nets Late Power-Play Goal in Losing Effort
Leo Carlsson

Pots Game-Winner Wednesday Night
Juraj Slafkovsky

Ends Point Drought in Game 1 Loss
Bowen Byram

Ties Franchise Record With Fourth Postseason Goal
Zach Benson

Posts Second Consecutive Multi-Point Game
Rasmus Dahlin

"Seems Fine" After Early Exit on Wednesday
Sam Merrill

Listed as Questionable for Thursday
Luke Kennard

Tagged as Questionable for Game 2 Against Thunder
Jarred Vanderbilt

Considered Doubtful for Thursday
Jalen Williams

Still Out Thursday
Carter Bryant

Available Wednesday Night
Luka Dončić

Luka Doncic Reveals Recovery Timeline
Anthony Edwards

Cleared for Game 2 Against Spurs
Emilio Pagán

Emilio Pagan has Grade 2 Hamstring Strain, Expected to Miss 4-8 Weeks
Joe Ryan

Listed as Scheduled Starter for Saturday Against Cleveland
Tyler Glasnow

Not Expected to Land on the Injured List
Framber Valdez

Suspension Reduced to Five Games
Nils Hoglander

Will Miss World Championship Due to Injury
Christian Dvorak

Likely to Play in Game 3 Against Hurricanes
Owen Tippett

a Game-Time Decision Thursday
Noah Cates

to Miss Rest of Round 2
Arber Xhekaj

Rejoins Canadiens Lineup Wednesday
Brendan Gallagher

Scratched on Wednesday
Logan Stanley

Returns to Action Wednesday
Framber Valdez

Suspended Six Games
Tyler Glasnow

Exits Early on Wednesday With Back Pain
CFB

Brauntae Johnson the Next Star in Notre Dame's Secondary?
CFB

Ethan Barbour a Name to Know in Georgia's Tight End Room
CFB

Payton Pierce Next Up at Linebacker for Ohio State
CFB

Javin Gordon to Play Significant Role for Tennessee?
CFB

Tanook Hines Stepping into WR1 Role for USC
CFB

Rueben Owens II has "Star Potential" in Fourth Campaign
Brandon Woodruff

has Fluid Drained From his Right Shoulder
Brandon Woodruff

to Resume Throwing on Saturday, Return Imminent?
Carlos Correa

to Have Season-Ending Ankle Surgery
Jacob Misiorowski

Listed as Friday's Probable Starter
Logan Webb

Dealing With Knee Discomfort
Carlos Correa

Expected to Miss Significant Time With Ankle Injury
Collin Morikawa

Withdraws From Truist Championship
Xander Schauffele

Carries Elite Form Into Quail Hollow
Hideki Matsuyama

Looks to Bounce Back at Truist Championship
Matt Fitzpatrick

Secures Third Win of 2026 Season
Patrick Cantlay

Continues Playing Well Heading to Truist Championship
Ludvig Aberg

Returns to Action For Truist Championship
Justin Thomas

Searching for Consistency at Quail Hollow
Jordan Spieth

Looks to Break Through at Quail Hollow
Adam Scott

Brings Strong Form to Quail Hollow
Robert MacIntyre

a Steady Option at Truist Championship
Jason Day

Looks to Overcome Approach Struggles at Quail Hollow
Akshay Bhatia

Looks for Complete Game at Truist Championship
Mats Zuccarello

Extends Point Streak to Five Games
Emilio Pagán

Emilio Pagan Headed for Injured List With Hamstring Injury
Emilio Pagán

Emilio Pagan Carted Off With Apparent Hamstring Injury on Tuesday
Justin Rose

to Continue Mid-Season Club Change at Truist Championship
Si Woo Kim

is Back to Peak Form Ahead of Truist Championship
Sam Burns

to Bounce Back at Truist Championship
Cameron Young

Looks to Carry Dominance to Quail Hollow
Rory McIlroy

Returns to Familiar Stomping Grounds This Week at Quail Hollow
Chris Gotterup

Looking to Bounce Back at Quail Hollow
MLB

Cardinals-Brewers Game Postponed on Tuesday
Roman Anthony

Day-to-Day With Wrist Sprain
Jacob Misiorowski

"All Things Look Good" for Jacob Misiorowski to Start on Wednesday
Tommy Fleetwood

Looking For Better Iron Play at Quail Hollow
MLB

Rockies-Mets Game Postponed Due to Inclement Weather
CFB

Mario Craver Enters No. 1 Wide Receiver Role for Marcel Reed
CFB

LaNorris Sellers a Strong Rebound Candidate in 2026
CFB

Cam Coleman Poised for Monster Year at Texas?
CFB

Will Hammond Pushing to Be Ready for Week 1
Alex Fitzpatrick

Looking to Keep Up Ball-Striking Output at Quail Hollow
CFB

Notre Dame Leads College Football in Returning Snaps
CFB

Two Ole Miss Football Players Arrested, Charged with DUI
Ben Griffin

Looks Solid on the Surface Heading to Charlotte
Chase Elliott

Earns his Second Texas Motor Speedway Victory
Denny Hamlin

Misses Out on Winning at Texas
Alex Bowman

Finishes Third for the Second Week in a Row at Texas
Tyler Reddick

Earns Seventh Top-Five Finish of the Season at Texas
Chris Buescher

Scores his First Career Texas Finish in the Top Five
CFB

Bryce Underwood in Better Situation Entering Sophomore Season
CFB

Nico Iamaleava Emerging as Leader, Playmaker for UCLA
Jack Della Maddalena

Gets Dominated At UFC Perth
Carlos Prates

Shines At UFC Perth
Beneil Dariush

Suffers A First-Round TKO Loss
Quillan Salkilld

Remains Unbeaten In The UFC
Tim Elliott

Drops Decision At UFC Perth
Steve Erceg

Wins Back-To-Back Fights
Ollie Schmid

Suffers First-Round TKO Loss
Marwan Rahiki

Remains Unbeaten
Christopher Bell

Is Christopher Bell Worth Rostering for Texas Lineups?
William Byron

Might have the Speed to Compete for the Win at Texas
Joey Logano

Provides Solid Upside for Texas DFS Lineups
Chase Briscoe

Could Chase Briscoe be A Sneaky Pick for Texas Lineups?
Ty Gibbs

Should DFS Managers Roster Ty Gibbs at Texas?
Daniel Suarez

Is Daniel Suarez Worth Rostering After Career-Best Starting Position at Texas?
Kyle Busch

Is a DFS Risk Starting in the Top 10 at Texas
Tyler Reddick

One of the Favorites to Win at Texas
Chase Elliott

Could Contend for Another Win at Texas
Carson Hocevar

on Pole at Texas
NASCAR

Bubba Wallace Wrecks in Practice at Texas
Chris Buescher

Looking to Continue Strong Run at Texas
Austin Dillon

Blows Engine in Practice at Texas
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF