TAP FOR 6 MONTHS OF PREMIUM FREE 💰
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

TNF NFL DFS Lineup Picks for FanDuel, DraftKings - 49ers vs Titans Showdown

John's top NFL DFS lineup picks for FanDuel, DraftKings and Thursday Night Football - the 49ers vs Titans showdown slate. His Week 16 TNF daily fantasy football advice.

Happy Thursday, RotoBallers! Week 16 is here! This season has been going by super quickly, and I can't believe that this is the last Thursday Night game of the season. We have a rather interesting contest tonight as the 49ers (8-6) head to Nashville to take on the Titans (9-5). This is a battle that should put a dent in the AFC West divisional race regardless of the result, and it should be an exciting one. Thanks to the advanced analytics of today, I'll do my best to provide you with as much in-depth analysis as possible regarding positional matchups and the like to help put some lunch money in your pocket. 

In this article I will be providing you with daily fantasy football picks on FanDuel and DraftKings for the Thursday Night Football slate on December 23rd. These lineups can vary from higher-priced players and elite options to lower-priced players and value picks on both DraftKings and FanDuel.

If you have any questions you can follow me on Twitter @LucidMediaDFS and fire away, or sign up for a premium RotoBaller NFL package and chat with me and other NFL DFS analysts any time you'd like. Let's make some coin this season gang, and let's get right to it!

Featured Promo: Looking for some more fantasy football action? Adopt a dynasty orphan team over at FFPC. Sign up today and get $25 off any FFPC league. Sign Up Now!

 

DFS Captains/MVPs for DraftKings, FanDuel

Ryan Tannehill ($15,000 DK, $15,000 FD)

Key Stats:

  • 2021 Stats: 3,118 passing yards, 14 touchdowns, 14 interceptions. 
  • Offensive Pass DVOA: -2.9% (26th)
  • Opposing Defense Pass DVOA: 7.1% (21st)

Tannehill hasn't necessarily had "the magic" as we saw from him last year, which we can partly blame on the loss of Derrick Henry mid-season. However, Tannehill is still very much "fantasy-viable" if you need a guy who has a solid floor. While his ceiling isn't too high, I can expect Tennessee to throw the ball quite a bit tonight, and getting A.J. Brown back in the lineup should provide the boost that Tannehill needs to have a solid game.

Recommendation: Cash/GPP (DK/FD)

Best Correlations: A.J. Brown, Deebo Samuel

 

Jeff Wilson Jr. ($7,800 DK, $11,000 FD)

Key Stats:

  • 2021 Stats: 65 attempts, 249 yards, one touchdown, five targets, four receptions, 19 yards. 
  • 2021 Data: 31.71% attempt rate, 30.43% red-zone attempt rate, 33.33% rate within the 5yd line, 3.68% target rate, 9.09% red-zone target rate, one end zone target.
  • Offensive Rush DVOA: 7.1% (4th)
  • Opposing Defense Rush DVOA: -9.5% (17th)

Jeff Wilson Jr. finally broke out last week to the cheers of DFS players everywhere. If I had to guess, he'll be one of if not the most expensive captains on the slate on DraftKings. His price is too cheap and he does have a solid matchup against a middle-of-the-road rushing defense. While I do have some concerns over Deebo Samuel taking 14 carries over the last two weeks, I would expect Kyle Shanahan to stick to his game plan of running the football so Wilson getting 10-12 touches seems inevitable. This creates a solid value opportunity, especially on DK, for Wilson to be in your captain spot.

Recommendation: Cash/GPP (FD/DK)

Best Correlations: Ryan Tannehill, George Kittle

Other Captain/MVP Plays: Deebo Samuel, A.J. Brown

 

DFS Flex Plays for DraftKings, FanDuel

Jimmy Garoppolo ($10,400 DK, $14,000 FD)

Key Stats:

  • 2021 Stats: 3,172 passing yards, 18 touchdowns, 8 interceptions.
  • Offensive Pass DVOA: 33.2% (4th)
  • Opposing Defense Pass DVOA: 4.8% (15th)

Every time I look at this year's DVOA and see the 49ers sitting at fourth it surprises me. All credit to them, but I certainly wouldn't rate them as the fourth-best passing offense in football. Regardless, Jimmy G has been throwing the pill around well of late. I don't really like going double QB on DraftKings and I prefer Tannehill to Garoppolo, but I will most likely be running Jimmy G in most of my FanDuel lineups.

Recommendation: Cash/GPP (FD/DK)

Best Correlations: George Kittle, Deebo Samuel, Ryan Tannehill

 

George Kittle ($11,200 DK, $13,000 FD)

Key Stats:

  • 2021 Stats: 82 targets, 63 receptions, 850 receiving yards, six touchdowns.
  • 2021 Data: 25.31% target rate, 17.95% red-zone target rate, five end zone targets.  
  • Individual Matchup (vs Jayon Brown): 11% target per route covered, 88% catch rate, 0.23 fantasy points per route. 

While to some there was never a doubt regarding Kittle's quality as a tight end, Kittle has certainly silenced any and all doubters over the last three weeks. He's logged 28 catches for 425 yards and three touchdowns in that span and has a very intriguing matchup against the Titans' defense (and Jayon Brown specifically) tonight. His price is steep, but for a guy who's been consistently putting up numbers of late, I want him in my lineups. I should note that I prefer him slightly over Deebo Samuel tonight but should have plenty of them both.

Recommendation: GPP (DK), Cash/GPP (FD)

Best Correlations: Jimmy Garoppolo, Ryan Tannehill

Other Flex Plays: A.J. Brown, Julio Jones, D'Onta Foreman

 

DFS Value Plays for DraftKings, FanDuel

49ers D/ST ($3,800 DK)

Key Stats:

  • 2021 Stats: 6 interceptions, 11 fumble recoveries, 36 sacks, two defensive touchdowns. 

There is a chance tonight that even with the return of A.J. Brown, the Titans' offense stalls and can't really get anything going tonight against a relatively hot SF defense. I'll most likely be using them in stacks with Jeff Wilson Jr. as well as some San Francisco onslaught stacks, but backing the Niners here is a solid way to create some space if you want both Kittle and Deebo in your lineups.

Recommendation: Cash/GPP (FD/DK)

Best Correlations: Jimmy Garopollo, Jeff Wilson Jr.

Robbie Gould ($4,400 DK, $9,000 FD)

While he hasn't been "as good as Gould" this season, he's still been pretty dang solid. He's knocked down 14 of 17 field goals and has missed just one extra point all season. He's logged at least seven fantasy points in each of the last four games, and that should continue tonight. I feel that regardless of how the game script goes, Gould should be optimal. Remember: kickers are always optimal.

Recommendation: Cash/GPP (FD/DK)

Best Correlations: Jimmy Garoppolo, Jeff Wilson Jr.

Other Value Plays: Nick Westbrook-Ikhine, Anthony Firkser

 

Overall Slate Note

This should be a fun slate with two offenses that seem rather consolidated and want their big boys to do most of the work for them. I'll have a ton of ownership among both teams' top skill-position guys, and just slightly more Tannehill than Jimmy G on both sites in tournaments. I don't have much to say as far as lineup restrictions go, other than the suggestion of not playing both Foreman and Hilliard in the same lineups. Outside of that, I'd like to thank you for reading my Thursday Night articles in this goofy but fun 2021 season. I also want to wish you a Merry Christmas, Happy Holidays, and wish you health and happiness for the rest of 2021 and throughout 2022. I'll catch you all on Sunday!

Have a good Thursday everyone, see you soon!



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Weekly DFS Analysis




POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Aaron Wiggins

is Ruled Out for Friday's Game
Bo Horvat

Rejoining Islanders Lineup Saturday
Dylan Holloway

Out Friday
Ross Colton

Won't Play Friday
Filip Chytil

Ready to End Three-Month Absence
Mason McTavish

Misses Second Straight Game Friday
Anthony Stolarz

Returns to Action Friday
Oliver Ekman-Larsson

Available Friday
Tyreek Hill

Dolphins Expected to Release Tyreek Hill
Paddy Pimblett

Set For Interim Lightweight Title Fight
Justin Gaethje

An Underdog At UFC 324
Song Yadong

Looks To Win Back-To-Back Fights
MMA

Sean O'Malley Looks To Get Back In The Win Column
Derrick Lewis

Returns At UFC 324
Waldo Cortes-Acosta

Looks For His Third Consecutive Win
Philip Rivers

Interviewing for Bills Head-Coaching Job
NFL

Fernando Mendoza Officially Declares for NFL Draft
CFB

Arch Manning Undergoes Foot Surgery
Dalton Kincaid

Played Through Torn PCL
CFB

College Football Playoff Expected to Remain a 12-Team Field in 2026
Duncan Robinson

Listed as Probable Friday Against Houston
Ja'Kobe Walter

to Miss Seventh Straight Game
Collin Murray-Boyles

Uncertain Friday Against Portland
RJ Barrett

Could Return Friday vs. Portland
Myles Turner

Expected to Play Friday vs. Nuggets
Sam Merrill

to Miss Fourth Straight Game Friday
Quinn Hughes

Makes History With Three-Assist Effort
Bennedict Mathurin

Remains Sidelined vs. Thunder
Anthony Mantha

Scores Twice Against Oilers
Alex Caruso

to Miss Another Game Friday vs. Indiana
Jet Greaves

Keeps Stars Off Scoreboard With 28 Saves
Ajay Mitchell

Won't Play Friday Against Indiana
David Pastrnak

Leads Bruins to Victory With Three-Point Effort
Isaiah Hartenstein

Still Sidelined Friday Against Indiana
Jonathan Huberdeau

on Track to Return Friday
Jonathan Kuminga

Leaves Thursday's Game With Knee Issue
Darcy Kuemper

Cleared for the Weekend
Deni Avdija

Likely Available Friday Despite Back Scare
Zach Benson

Hurt in Thursday's Win
Norman Powell

Ready to Face Trail Blazers
Robert Williams III

Active Thursday Night
Jerami Grant

Sidy Cissoko Cleared to Play
Kawhi Leonard

Returns to Action Thursday
Jrue Holiday

Available Against Heat
Davion Mitchell

Will Miss Thursday's Game
Santi Aldama

Won't Play Friday
Ja Morant

to Skip Friday's Game
Baltimore Ravens

Ravens Hire Jesse Minter as Their Head Coach
Kris Letang

Questionable Thursday
Andre Burakovsky

Frank Nazar, Andre Burakovsky Available for Blackhawks Thursday
Indianapolis Colts

FBI Investigating the Death of Colts Owner Jim Irsay
Mason Marchment

Available Versus Stars
Alexandre Texier

Misses Second Consecutive Game
Marcus Johansson

Joel Eriksson Ek, Marcus Johansson Could Return Thursday
David Perron

to Miss 5-7 Weeks Due to Hernia Surgery
Mikko Rantanen

Unavailable Thursday
MacKenzie Gore

Rangers Acquire MacKenzie Gore From the Nationals
Brandon Sproat

Dealt to Brewers in Four-Player Trade
Jett Williams

Brewers Acquire Jett Williams From Mets
Freddy Peralta

Mets Acquire Freddy Peralta From Brewers
Kyle Tucker

Expected to Bat Second or Third in Dodgers' Lineup
Brandon Aiyuk

has "Played his Last Snap as a Niner"
Cody Bellinger

Signs Five-Year, $162.5 Million Contract With Yankees
Adam Scott

Looks to Overcome Putting Woes at American Express
Billy Horschel

Looking to Rebound at The American Express
Josh Allen

Might Need Foot Surgery
Russell Henley

Looks to Build on Strong Start at The American Express
Jason Day

Looking to Start 2026 Strong at The American Express
Wyndham Clark

Looking to Regain Form at The American Express
Sam Burns

Looks to Continue Success at The American Express
Akshay Bhatia

Looking to Flip the Script at The American Express
Christiaan Bezuidenhout

Looking to Build on Strong Fall in Season Debut
Kurt Kitayama

Hopes To Continue Strong Start to 2026 Season at American Express
CFB

Princewill Umanmielen Expected to Sign with LSU
Scottie Scheffler

Returns To American Express After Missing Last Year's Edition
Robert MacIntyre

Keeps Momentum Rolling Heading Into American Express
Brian Harman

Can Challenge at American Express if His Putter Stays Hot
Ben Griffin

Outstanding Form Continues Heading Into American Express
Matt Fitzpatrick

Continues Playing Well Following Outstanding Finish to 2025 Season
Patrick Cantlay

Looks to Get a Jump Start on His 2026 Season
Blades Brown

Set to Make First PGA Tour Appearance of 2026
Kevin Roy

Has Some Confidence Heading to Southern California
Min Woo Lee

Poised to Make Bigger Impact in 2026
Max Homa

Needs a Better Start for 2026
Tony Finau

Trying to Reverse Disturbing Trend
Cam Davis

Aims for More Accuracy at American Express
Luisangel Acuña

Luisangel Acuna Sent to White Sox in Trade
Luis Robert Jr.

Mets Acquire Luis Robert Jr. from White Sox
Los Angeles Chargers

Mike McDaniel Expected to Become Chargers Offensive Coordinator
Carlos Beltran

Andruw Jones Elected to Baseball Hall of Fame
CFB

Alberto Mendoza Expected to Land at Georgia Tech
Malik Nabers

Giants Hope Malik Nabers Will be Back for Start of Training Camp
CFB

Duke Suing Quarterback Darian Mensah
Cam Skattebo

Should be Ready by OTAs
George Kittle

Expects to Return "Well Before November"
CFB

Alberto Mendoza Entering Transfer Portal
Mookie Betts

Plans to Retire at the End of his Current Contract
Tennessee Titans

Titans Set to Hire Robert Saleh as Next Head Coach
Miami Dolphins

Dolphins Expected to Hire Jeff Hafley as Next Head Coach
Zach Charbonnet

has Torn ACL
Zach Charbonnet

Needs Knee Surgery, Out for Rest of Playoffs
Tennessee Titans

Mike McCarthy a Finalist for Titans Head-Coaching Job?
Colston Loveland

Suffers Concussion in Divisional Round Loss
Kyren Williams

Scores Two Touchdowns in Divisional Round Win
Buffalo Bills

Bills Fire Head Coach Sean McDermott
Rhamondre Stevenson

Returns in Sunday's AFC Divisional Round Game
Ha-Seong Kim

has Finger Surgery, Out 4-5 Months

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP