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PrizePicks NFL DFS Picks - Rams vs. 49ers Monday Night Football

Brandon Aiyuk - Fantasy Football Rankings, NFL Injury News

Kipp Heisterman presents his Fantasy Score NFL DFS picks on PrizePicks for Week 4 of Monday Night Football. Use his NFL prop picks recommendations to win money on PrizePicks.

Hello everybody and welcome! The 2022 NFL season is underway and that means our friends over at PrizePicks have a TON of great props we can look to take advantage of. PrizePicks is a great DFS picks site where you can choose to select plays in terms of fantasy points or single stats. The goal is to build a 2-player, 3-player, 4-player, or 5-player entry and then select whether or not you want to play for the power play or the flex play. On the power play, you will need to be correct on each of your selections to win, and on the flex play, you will have a little more wiggle room for a chance to win some money back.

Our partners at PrizePicks offer some of the best and easiest to win NFL DFS games in the industry. There are no large-field tournaments filled with sharks where you have to get lucky just to place. At PrizePicks, you're not playing against other people, you're just playing against the projections, and the guys at PrizePicks have worked hard to give you really attractive opportunities to make some money. With promo code 'BALLER' you can get a 100% match on your deposit up to $100.

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NFL DFS Picks for Rams at 49ers

Before diving into some solid fantasy score totals this week, we must first cover the PrizePicks scoring format. The format is PPR, which stands for point per reception, meaning every reception is worth one point. Rushing and receiving touchdowns are worth six points and passing touchdowns are worth four points.

Each rushing or receiving yard is worth .1, meaning every 10 yards of either is worth one point. Quarterback passing yards are worth .04, which means every 25 passing yards are worth one point. If you ever have questions, you can always click the "scoring chart" option above the player selections for each contest. Now, let's get to some solid fantasy score props for this week.

Brandon Aiyuk more than 49.5 receiving yards - Aiyuk is one of my favorite guys to play when the opposing defense has a solid number-one cornerback like Jalen Ramsey for the Rams as he tends to get free a lot more. Last season, Aiyuk eclipsed this total in six of his last eight games while averaging over six targets per game. Last week with Jimmy G. under center, he was once again targeted eight times and could be in line for a similar share in this game.

Cam Akers more than 9.5 receiving yards -This is a gut feeling as Akers has seen his snap share increase steadily over the first three weeks of the season as he capped out at a 50% share last week. The Niners' defense is stout; however, they have allowed 18 receptions to running backs over the first three weeks of the season, which ranks ninth-worst in the league. If Akers is able to haul in a target or two, he could have a legitimate shot of getting over this total.

Matthew Stafford less than 250.5 passing yards - Stafford is certainly capable of eclipsing this total; however, he has only done it once this season, and the matchup against San Francisco is going to be tough. Through the first three weeks of the season, the Niners have allowed the fewest passing yards to quarterbacks per game by allowing an average of just 167 yards per game. Stafford also failed to reach this total in both of his regular-season starts against the Niners in 2021.

Other Recommendations: Brandon Aiyuk more than 4.0 receptions, 

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REAL-TIME FANTASY NEWS

Lamar Jackson

Will Officially Return in Week 18
Tobias Harris

Won't Suit Up Against Miami
Lauri Markkanen

on the Injury Report for Thursday Night
Keyonte George

Battling an Illness, Might Miss Thursday's Game
Jusuf Nurkić

Jusuf Nurkic Won't Play on Thursday Evening
Houston Astros

Astros Sign Tatsuya Imai to Three-Year Deal
Jordan Love

Clears Concussion Protocol, Won't Start in Week 18
George Kittle

"Absolutely" Expects to Play in Week 18
Clayton Tune

to Start for Packers in Week 18
Chris Olave

Ruled Out for Week 18
Tom Wilson

Wraps Up 2025 With Gordie Howe Hat Trick
Valeri Nichushkin

Nets Second Career Hat Trick
Frank Vatrano

to Miss Six Weeks With Shoulder Injury
Conor Sheary

Noah Laba Exit With Injuries Wednesday
Brayden McNabb

Suffers Upper-Body Injury Wednesday
Miles Wood

Exits Early Wednesday
Gavin Brindley

Sustains Upper-Body Injury
Michael Porter Jr.

Battling Illness, Questionable Thursday
Joel Embiid

Likely to Play Thursday
Anthony Davis

Available Thursday
Coby White

to Miss at Least One Week
Josh Giddey

to Be Re-Evaluated in Two Weeks
Jonas Valančiūnas

Jonas Valanciunas in Walking Boot After Suffering Calf Injury
Victor Wembanyama

Expects to Play Next Game After Suffering Minor Knee Injury
Davante Adams

Not Expected to Play in Week 18
Stephon Castle

Active on Wednesday
Tyler Kolek

Elevated to Available on Wednesday
Tari Eason

Questionable Versus Brooklyn
Tobias Harris

Not Expected to Suit Up on Thursday
Ariel Hukporti

Available For Wednesday
Alperen Sengün

Alperen Sengun Questionable Versus Brooklyn
Mason Plumlee

Undergoes Groin Surgery
Zach Collins

Out at Least 10 More Days
Jerami Grant

Unavailable Again on Wednesday
Geno Smith

Won't Play in Week 18
Aaron Rodgers

Considering Playing Beyond 2025?
Sean Monahan

Sits Out Wednesday's Game
Zach Werenski

Misses Fourth Straight Game Wednesday
Dougie Hamilton

Questionable Wednesday
Radko Gudas

Expected to Remain Out Wednesday
Stefon Diggs

Expected to Play in Week 18
Ilya Lyubushkin

Back From One-Game Absence Wednesday
Alex Lyon

to Miss "Bit of Time"
Erik Cernak

Rejoins Lightning Lineup Wednesday
Christian McCaffrey

Trending to Play in Week 18
Kon Knueppel

To Make Return For Charlotte On Wednesday, In Starting Lineup
Jalen Hurts

Eagles Expected to Rest Jalen Hurts, Most Starters in Week 18
George Kittle

49ers Will be "Very Surprised" if George Kittle Doesn't Play on Saturday
Marvin Harrison Jr.

Ruled Out for Regular-Season Finale
CFB

Lane Kiffin Interested in Sam Leavitt, Brendan Sorsby at LSU
Shakir Mukhamadullin

Questionable Wednesday
Adam Gaudette

Unavailable Wednesday
Darcy Kuemper

Activated From Injured Reserve
Alex Lyon

Nursing Lower-Body Injury
William Karlsson

to Miss Olympics
Jack Eichel

a Game-Time Decision Wednesday
Jason Dickinson

Hurt Versus Islanders
CFB

Deuce Knight Officially Entering Transfer Portal
CFB

Kewan Lacy Expected to Be Full-Go Against Georgia
Stefon Diggs

Facing Strangulation, Assault Charges
CFB

Chip Kelly Named Northwestern Offensive Coordinator
Riley Leonard

Will Start Against the Texans
Bijan Robinson

Explodes for 229 Total Yards, Two Touchdowns on Monday Night
Davante Adams

Officially Out on Monday Night
Drake London

Active Against Rams
Justin Herbert

Won't Face Broncos in Week 18
Marcus Mariota

Considered "a Stretch" to Play in Week 18
Geno Smith

Dealing With Significant Ankle Injury
CFB

Penn State Working to Hire D'Anton Lynn as Next Defensive Coordinator
CFB

Omar Cooper Expected to be Full-Go for Rose Bowl
CFB

Marcus Freeman Staying with Notre Dame for 2026 Season
CFB

Star Wideout Cam Coleman Entering Transfer Portal
CFB

Jay Hill Expected to be Next Michigan Defensive Coordinator

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