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PrizePicks MLB DFS Picks for Fantasy Baseball - Wednesday September 21st

Lance McCullers - Fantasy Baseball Rankings, Draft Sleepers, MLB Injury News

Kipp's MLB DFS prop picks for PrizePicks daily fantasy baseball on Wednesday, September 21st. Use his MLB prop picks recommendations to win money on PrizePicks.

Hello everybody and welcome! The 2022 MLB season is heading towards the home stretch and we here at RotoBaller have you covered with some terrific plays from our friends over at PrizePicks.

PrizePicks is a great DFS fantasy picks site where you can choose to select plays in terms of fantasy points or single stats. The goal is to build a 2-player, 3-player, 4-player, or 5-player entry and then select whether or not you want to play for the power play or the flex play. On the power play, you will need to be correct on each of your selections to win, and on the flex play, you will have a little more wiggle room for a chance to win some money back.

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PrizePicks has two types of games. The first type of game is known as Fantasy Score, which consists of selecting various players and trying to determine if they will go over or under their projected fantasy points in a game. The second game is known as Single Stat. For MLB, Single Stat consists of pitcher strikeout props in which you determine if the pitcher in question will go over or under their projected strikeout total. You can mix and match players from each type of game in your entry or select all of your plays from the same type of game. Once you have selected your players and props, you can choose the aforementioned flex play or power play option. Let's see what the board offers today!

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MLB DFS Picks for 9/21/22

Daniel Lynch more than 4.5 strikeouts- Lynch is not the first guy I thought I would be writing up today, but the matchup is ripe. He will be facing the Twins, who have posted a 29.7% K rate vs. southpaws over the previous two weeks, which is ranked fourth-worst in the league. Lynch is also fresh off an eight-strikeout performance against these Twins in his most recent start

Robbie Ray more than 6.5 strikeouts - Ray has a solid matchup in this one against the Athletics, who have posted a K rate of 31% vs. lefties over the previous two weeks, which is ranked second-worst in baseball over that span. They have also posted just a 4.8% walk rate and an 81 wRC+ mark over that same span, so Ray should be able to stay out of trouble in this one. He has faced Oakland three times this season and has eclipsed this total in two of those three starts.

Lance McCullers Jr. more than 5.0 strikeouts - McCullers has looked sharp since his return from the IL and now has five or more strikeouts in all but one start in that timeframe. He will be facing the Rays, who have posted just a 20% K rate vs. righties over the previous two weeks, but have not faced many starters with the strikeout upside of McCullers over that span.

Other Recommendations - 

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REAL-TIME FANTASY NEWS

Rasmus Ristolainen

Doesn't Finish Wednesday's Loss
Blake Coleman

Out Until Olympic Break
Aaron Gordon

Out Thursday
Isaiah Hartenstein

Available Thursday
Russell Westbrook

Questionable to Play Thursday
Zach LaVine

Returns From Two-Game Absence
Paul George

Expected to Play Against Kings
Joel Embiid

Probable Thursday
Steven Adams

Undergoes Season-Ending Ankle Surgery
Egor Demin

Won't Play Versus Denver
Cam Thomas

Resting on Thursday Night
Aaron Judge

Appears to be Past his Elbow Issues
Bo Nix

Expected to Resume Training in 4-6 Weeks
Dan Vladar

Returns to Flyers Crease
Denton Mateychuk

Back in Action Wednesday
Stephen Halliday

Unavailable Versus Avalanche
Ross Colton

Won't Play Wednesday
Devon Toews

Still Out Wednesday
Simon Holmstrom

Expected to Return Wednesday
Ryan Pulock

a Game-Time Call Wednesday
Michael Penix Jr.

Thinks he'll be Ready by April
Evan Carter

Establishes a Goal to Steal 30 Bases
Edouard Julien

Traded to the Rockies
Cleveland Browns

Browns Hiring Todd Monken as Next Head Coach
Jack St. Ivany

to Miss Up to Eight Weeks After Surgery
Cody Glass

Exits Early Tuesday Night
Anton Lundell

Expected to Be Available Thursday
Jordan Kyrou

Jake Neighbours Knocked Out of the Lineup Tuesday
Elias Lindholm

Hurt in Tuesday's Win
Ukko-Pekka Luukkonen

Exits With Injury Tuesday
Ondrej Palat

Devils Send Ondrej Palat to the Islanders
Collin Murray-Boyles

Listed as Questionable for Wednesday's Game
Jock Landale

Available for Wednesday's Tilt
Kel'el Ware

in Danger of Missing Another Game
Sahith Theegala

Off to Much Better 2026 Start
Davion Mitchell

Iffy for Wednesday
Gary Woodland

an Intriguing Option at Torrey Pines This Week
Norman Powell

Questionable Wednesday
Tyler Herro

Remains Out Wednesday
CJ Abrams

Giants Offer "Aggressive Pitch" for CJ Abrams
Andrew Putnam

Hopes to Keep Momentum Rolling This Week
Nikola Jokić

Nikola Jokic to Be Re-Evaluated in One Week
Matthieu Pavon

Seeks to Return to 2024 Form at Torrey Pines
Luke List

Still Looking For Birdies at Torrey Pines
Jake Knapp

Faces Stiff Challenge at Farmers Insurance Open
Rasmus Hojgaard

Needs to Play Better at Torrey Pines
Christiaan Bezuidenhout

Could Struggle at Farmers Insurance Open
J.J. Spaun

A Steady Option At Farmers Insurance Open
Andrew Novak

Looking For More Success At Torrey Pines
Denny McCarthy

A Wild Card At Farmers Insurance Open
Max Homa

Looks To Keep Resurgence Going At Torrey Pines
Joe Highsmith

Struggling Heading Into Torrey Pines
Wyndham Clark

Looks To Carry Momentum Into Farmers Insurance Open
Tony Finau

Aims To Turn Things Around At Torrey Pines
Darius Garland

Won't Be Available Wednesday
Akshay Bhatia

Looks to Bounce Back at Torrey Pines
Franz Wagner

Won't Play Wednesday
Draymond Green

Expected to Return Wednesday
Kawhi Leonard

Available Against Jazz
Jordan Goodwin

Starts Against Nets
Paul Goldschmidt

Yankees Expressing Interest in Re-Signing Paul Goldschmidt
Bo Bichette

Won't Play in World Baseball Classic
NFL

Bill Belichick Won't be First-Ballot Hall of Famer
Leo Carlsson

to Miss Olympics
Alex Turcotte

Unavailable Tuesday
Carlos Correa

Won't Play for Puerto Rico in World Baseball Classic
Dylan Holloway

Remains Out Tuesday
Marco Rossi

to Return After Olympics
Thatcher Demko

Won't Return This Season
Si Woo Kim

Looks to Continue Incredible Run at Torrey Pines
Jason Day

has a Good Chance to Keep Momentum This Weekend
Keegan Bradley

has Good Course History at Torrey Pines
Billy Horschel

Isn't a Great DFS Option at Torrey Pines
Aaron Rodgers

Mike McCarthy Says he Wants Aaron Rodgers to Return
Will Zalatoris

Has a Shot to Challenge at the Farmers Insurance Open
Drake Maye

Expected to be Fine for Super Bowl
Tennessee Titans

Titans Set to Hire Brian Daboll as New Offensive Coordinator
Buffalo Bills

Bills Promote Joe Brady to Head Coach
CFB

Quarterback Brayden Fowler-Nicolosi Signs with Michigan
CFB

Darian Mensah Reaches Settlement with Duke, Expected to Land at Miami
Eugenio Suárez

Eugenio Suarez Not Drawing Interest on Open Market?
Shedeur Sanders

Named as Pro Bowl Replacement
Framber Valdez

Among Many High-End Pitchers on Free-Agent Market
Jose Altuve

Won't Participate in World Baseball Classic
Harrison Bader

Agrees With Giants on Two-Year Deal
Paddy Pimblett

Drops Decision
Justin Gaethje

Becomes the New Interim-Lightweight Champion
Song Yadong

Suffers Unanimous Decision Loss
MMA

Sean O'Malley Gets Back In The Win Column
Waldo Cortes-Acosta

Extends His Win Streak
Derrick Lewis

Suffers Second-Round TKO Loss
Los Angeles Chargers

Chargers Officially Hire Mike McDaniel as Offensive Coordinator
Nathan Eovaldi

Doesn't Expect Any Limitations in Spring Training
Jaxon Smith-Njigba

Dominates in NFC Championship Game Win
Matthew Stafford

Plans to Return in 2026
CFB

Arthur Smith to Become Ohio State's Offensive Coordinator
Bo Nix

Sidelined for 12 Weeks With Broken Ankle
Jose Altuve

to Mainly Play Second Base
Yu Darvish

Considering Retirement
Pittsburgh Steelers

Steelers Finalizing Deal to Make Mike McCarthy Their Head Coach
José Ramírez

Jose Ramirez Signs Seven-Year Extension With Guardians
Gunnar Henderson

is Fully Healthy Heading into Spring Training
Tyreek Hill

Dolphins Expected to Release Tyreek Hill
Paddy Pimblett

Set For Interim Lightweight Title Fight
Justin Gaethje

An Underdog At UFC 324
Song Yadong

Looks To Win Back-To-Back Fights
MMA

Sean O'Malley Looks To Get Back In The Win Column
Derrick Lewis

Returns At UFC 324
Waldo Cortes-Acosta

Looks For His Third Consecutive Win
Philip Rivers

Interviewing for Bills Head-Coaching Job
NFL

Fernando Mendoza Officially Declares for NFL Draft
CFB

Arch Manning Undergoes Foot Surgery
Dalton Kincaid

Played Through Torn PCL
CFB

College Football Playoff Expected to Remain a 12-Team Field in 2026

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