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Oct 12, 2026, 9:59 AM ET

San Francisco 49ers wide receiver Deebo Samuel Sr. (hamstring) is scheduled to undergo an MRI to determine the severity of his injury. Samuel suffered a hamstring injury on a play that resulted in a fumble and was ruled out shortly after he went down. 49ers head coach Kyle Shanahan did not provide an update on the injury's severity in the post-game press conference but said, "I'll probably have one for you guys tomorrow, but I don't think he's coming back this week." In five games, Samuel has 16 catches for 206 yards and three touchdowns, plus 78 yards on the ground. If he misses time, Jacob Cowing and Brandin Cooks should help fill in, but the stars Mike Evans, George Kittle, and Christian McCaffrey will see upticks in usage as well. Fantasy managers should monitor this situation, as Samuel seems likely to miss time with his hamstring injury.--Nathan Harvey
Source: Ian Rapoport - NFL Network
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Oct 12, 2026, 9:58 AM ET

New York Jets rookie tight end Kenyon Sadiq (concussion) is in the concussion protocol, according to head coach Aaron Glenn. Sadiq suffered the concussion in the third quarter of the 17-12 win over the Cleveland Browns and did not return. He had just two receptions for three yards before the injury, likely due to the inclement weather they played in for most of the game. Glenn also said at the postgame press conference that some players could return in Week 6, including Breece Hall, Adonai Mitchell, Mason Taylor, and rookie Omar Cooper Jr. If those playmakers return, it would be detrimental to Sadiq's value, as he's been serving as the second option in the passing game. Fantasy managers should monitor Sadiq's practice status throughout the week, as well as the other playmakers who could return after their absences.--Nathan Harvey
Source: Rich Cimini - ESPN
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Oct 12, 2026, 9:40 AM ET

Atlanta Falcons wide receiver Drake London hauled in seven of 11 targets for 118 yards in the 30-23 loss to the Baltimore Ravens. After a quiet first half, London woke up, catching six passes for 93 yards in the second half and overtime. While he strung together his third straight productive game, this outing had some negatives. Quarterback Michael Penix Jr. suffered a rib injury and couldn't return late in the game. London has had incredible success with Penix as the starter, and any absence could affect his fantasy value. He also appeared to limp off the field after backup Tua Tagovailoa threw the final interception. It could be nothing, but fantasy managers should monitor practice reports if he's not participating. If he and Penix are healthy, fire up the star receiver as a WR1 in fantasy this season.--Nathan Harvey
Source: ESPN
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Oct 12, 2026, 9:18 AM ET

Atlanta Falcons quarterback Michael Penix Jr. (ribs) is expected to undergo an MRI on Monday to assess the severity of his injury. Penix suffered a rib injury late in the 30-23 loss to the Baltimore Ravens. Although he tried to throw on the sideline, he couldn't return to the game. Over this three-game stretch, he has completed 52 of 77 passes for 719 yards, three touchdowns, and one interception, while helping the Falcons' offense average 34.3 points per game when he starts. If Penix misses time with his rib injury, veteran Tua Tagovailoa will back him up. Tagovailoa was expected to start at quarterback at the beginning of the 2026 season while Penix recovered from a torn ACL, but an oblique injury sidelined the former Miami Dolphins quarterback. While both Penix and Tagovailoa carry minimal fantasy value, Penix's absence could affect the Falcons' playmakers, who have dominated over the last three games. For what it is worth, Penix does not think his injury is a long-term one.--Nathan Harvey
Source: Adam Schefter - ESPN
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Oct 12, 2026, 9:10 AM ET

Pittsburgh Steelers wide receiver Roman Wilson (finger) is expected to miss a few weeks, according to ESPN's Jeremy Fowler. Wilson sustained a finger injury in Sunday's 34-22 win over the Indianapolis Colts. While he's still gathering information and seeking a second opinion, he's likely to miss time. He was held to one target and no receptions in Week 5, but had back-to-back games with more than three receptions, 60 yards, and a touchdown. With Wilson expected to miss a few weeks, rookie receiver Germie Bernard will be the primary beneficiary. Bernard caught six of nine targets for 80 yards in Week 5, playing a career-high 91.7% of snaps. Fantasy managers who currently have Wilson should consider adding Bernard as a replacement.--Nathan Harvey
Source: Jeremy Fowler - ESPN
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Oct 12, 2026, 1:25 AM ET

Seattle Seahawks wide receiver Jaxon Smith-Njigba caught five of his eight targets for 102 yards and one touchdown during Sunday's Week 5 loss against the San Francisco 49ers. The 24-year-old is already closing in on 600 receiving yards so far this season, and he's up to seven touchdowns through five weeks. In addition to helping keep the Seahawks in a prime spot for a playoff push, Smith-Njigba is living up to the hype that came with his mid-first-round draft capital in redraft leagues. It is worth noting that Smith-Njigba did briefly exit Sunday's game with an apparent leg injury. He returned to the contest and continued to play at a remarkable level, but it will be something worth monitoring as the Seahawks publish their practice participation reports ahead of Week 6 against the Denver Broncos.--Andersen Pickard
Source: RotoBaller
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Oct 12, 2026, 1:08 AM ET

Detroit Lions tight end Sam LaPorta caught all five of his targets for 88 yards and one touchdown during Sunday's Week 5 win over the Arizona Cardinals. The headline of his big outing was a 38-yard touchdown reception that gave Detroit a 14-7 lead in the second quarter. The 25-year-old is off to a fantastic start this season, catching a touchdown pass in three of his five games so far. He also has five-plus catches in four of his five games. LaPorta has shown that he can operate as a mid-range TE1 in fantasy football despite sharing volume with Amon-Ra St. Brown, Jahmyr Gibbs, and Jameson Williams. There is plenty of production to go around in this offense, especially in a game like Sunday's, where the Lions racked up 45 points and 412 yards of total offense. LaPorta should continue to be started in all fantasy leagues on the other side of Detroit's Week 6 bye.--Andersen Pickard
Source: RotoBaller
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Oct 12, 2026, 12:59 AM ET

Jacksonville Jaguars quarterback Trevor Lawrence completed 24 of his 39 pass attempts for 331 yards, two touchdowns, and one interception during Sunday's Week 5 win over the Philadelphia Eagles. He also rushed for 23 yards and took two sacks. The 27-year-old has demonstrated lower rushing upside this year compared to last, but he hasn't missed a beat in terms of passing productivity. Through five games, he has 1,174 passing yards and 10 touchdowns, establishing himself as a strong low-end QB1 in fantasy football. He has also shown off a clutch factor, leading a comeback drive in the waning minutes of Sunday's game in London. While the Eagles did briefly pull back ahead after Lawrence's late touchdown drive, Jacksonville put the nail in the coffin with an improbable kick return and a long field goal. The 4-1 Jaguars operate a pass-heavy offense, and Lawrence should continue to benefit as a result. He should be started in most fantasy leagues ahead of Week 6 against the one-win Houston Texans.--Andersen Pickard
Source: RotoBaller
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Oct 12, 2026, 12:53 AM ET

Cincinnati Bengals wide receiver Ja'Marr Chase caught six of his 10 targets for 77 yards and one touchdown during Sunday's Week 5 win over the Miami Dolphins. Chase suffered a concussion in Week 4, but he managed to clear protocol in seven days and was able to continue producing as a strong WR1 this Sunday. The 26-year-old is now up to 27 catches, 289 yards, and two touchdowns through five games this season. He's headed for a bye in Week 6, but he'll return on the other side of the off week as a high-end WR1 who should be started in all fantasy leagues. As long as quarterback Joe Burrow stays healthy, Chase will continue to be a top fantasy weapon while proving that he can coexist alongside another high-scoring receiver, Tee Higgins.--Andersen Pickard
Source: RotoBaller
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Oct 12, 2026, 12:40 AM ET

San Francisco 49ers wide receiver Christian Kirk (calf) will likely remain on injured reserve even after he's eligible to be activated in Week 6, according to Nick Wagoner of ESPN.com. Following Sunday's win over the Seattle Seahawks, head coach Kyle Shanahan told Wagoner that he hasn't officially decided whether Kirk will be activated next week, but the answer would be no right now. That's not exactly the news that 49ers fans wanted to hear, as their team's wide receiver room has been absolutely decimated by injuries. In addition to Kirk, the 49ers are without De'Zhaun Stribling (ankle), Ricky Pearsall (right knee), and Deebo Samuel Sr. (hamstring). Pearsall is on season-ending IR, but assuming the other three players don't suit up in Week 6, we can expect Jacob Cowing and Brandin Cooks to occupy complementary roles behind Mike Evans.--Andersen Pickard
Source: RotoBaller
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Oct 12, 2026, 12:20 AM ET

Atlanta Falcons quarterback Michael Penix Jr. (rib) exited late in the fourth quarter of Sunday Night Football against the Baltimore Ravens. He actually returned for one play before the end of regulation, but then he spent the entire overtime period on the sideline. Officially, the Falcons designated him as questionable to return. Penix had led the Falcons to three different eight-point leads, but a late Baltimore comeback, coupled with a costly Tua Tagovailoa interception, gave the Ravens a road victory and snapped Atlanta's two-game winning streak. Penix will surely undergo additional testing to diagnose his injury and estimate a timetable for his return. If the 26-year-old has to miss any time, Tagovailoa would start at quarterback in Week 6 against the Chicago Bears.--Andersen Pickard
Source: Tori McElhaney
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Oct 11, 2026, 11:30 PM ET

It was not a perfect day for Seattle Seahawks running back Emanuel Wilson by any means in Sunday's 32-29 loss at home to the division-rival San Francisco 49ers, but he did have a workhorse role once again in Seattle's backfield. Wilson handled 20 carries on the day for 61 yards (3.1 yards per carry) and another touchdown. He caught both of his targets in the passing game for 11 yards. Wilson also lost a fumble on a day in which the Seahawks' offense turned the ball over four total times. Backup George Holani only had four carries for seven yards and also lost a fumble. The 27-year-old now has three 20-plus-carry games in 2026 after producing 120 scrimmage yards and two touchdowns (one rushing, one receiving) in last week's win over the Los Angeles Chargers. Rookie first-rounder Jadarian Price (chest) is on Injured Reserve, and Zach Charbonnet (knee) will not make his 2026 debut in next Thursday night's road contest in Denver against the Broncos, so Wilson is primed to take on the lead-back role once again for Seattle in Week 6. He should be considered an RB2 against a Broncos defense that has been vulnerable to the rushing attack so far in 2026.--Keith Hernandez
Source: NFL.com
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Oct 11, 2026, 11:20 PM ET

Green Bay Packers second-year wide receiver Matthew Golden could not find the end zone in the team's Week 5 blowout win over the division-rival Chicago Bears, but he had a 100-yard performance for the second time in the last three weeks. In the 31-7 win on Sunday, Golden caught six of his seven targets for a season-high 123 yards. He tied Christian Watson for the team lead in catches and was one shy of Watson in targets. Golden averaged a healthy 20.5 yards per catch, but Watson had 23.8 yards per catch and both of quarterback Jordan Love's passing touchdowns. With Romeo Doubs and Dontayvion Wicks no longer in town, Golden is seeing the breakout that many projected in his second season in the NFL. There is enough volume to go around in this Green Bay Offense (still without starting RB Josh Jacobs) for both Watson and Golden to be every-week starters in fantasy football lineups. Golden has a great matchup to go over the 100-yard mark for the second straight week in next Sunday night's game against the Dallas Cowboys.--Keith Hernandez
Source: NFL.com
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Oct 11, 2026, 11:06 PM ET

Pittsburgh Steelers quarterback Aaron Rodgers completed 22 of his 31 pass attempts for 235 passing yards, three passing touchdowns, and zero interceptions during Sunday's Week 5 win over the Indianapolis Colts. He also rushed for six yards and took just one sack. Rodgers has absolutely racked up fantasy points lately, tallying nine passing touchdowns through the last three weeks. Some turnovers and sacks left a bitter taste after Rodgers' previous explosive performances, but that wasn't the case on Sunday, as the veteran quarterback played turnover-free football. The 42-year-old passer lacks the mobility needed to be a high-end fantasy quarterback, but his latest track record could put him back on the fantasy radar as a potential midseason pick-up.--Andersen Pickard
Source: RotoBaller
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Oct 11, 2026, 11:02 PM ET

New York Jets wide receiver Garrett Wilson caught seven of his 11 targets for 104 receiving yards and one touchdown during Sunday's Week 5 win over the Cleveland Browns. After a disappointing outing in Week 4, Wilson got back on track this weekend with his second-best fantasy performance of the season. The 26-year-old has solidified himself as a WR1 in fantasy football, and he has fared better with Geno Smith at quarterback than he did with a combination of Justin Fields, Tyrod Taylor, and Brady Cook in 2025. Although we can't guarantee that Smith will be able to support top-tier production from Wilson every week, the duo has certainly looked solid so far. Wilson is a potential WR1 option for Week 6 against New England, but his exact outlook will depend on whether Patriots cornerbacks Christian Gonzalez (shoulder) and Carlton Davis III (neck) play next Sunday.--Andersen Pickard
Source: RotoBaller

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