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NFL DFS Prop Picks for Week 6 - Monkey Knife Fight

Patrick Mahomes - Fantasy Football Rankings, DFS Lineup Picks, NFL Injury News

Kipp Heisterman presents his expert NFL DFS prop picks for Week 6 of the Fantasy Football season. Use these prop picks to win money on Monkey Knife Fight, our partner for all DFS prop picks games.

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As always, there are a few games we can look to target this week including the Texans at Chiefs, Falcons at Cardinals, and Seahawks at Browns.

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Texans @ Chiefs

Over/Under Contest

Recommended Prop Pick: Two of two: Patrick Mahomes over 329.5 passing yards and Deshawn Watson over 298.5 passing yards.

This game is going to be a shootout in Kansas City. The total is 55, which is the highest on the board and both have very capable offenses going up against subpar defenses. The Texans have allowed 1,463 passing yards to quarterbacks through the first five games, which ranks third-worst in the league on a total yards basis. Only the Dolphins and Lions rank worse on a yards per game basis.

Add in the fact that Mahomes has thrown for over 300 yards in every game this season while averaging 366.2 yards per game and you have a solid play on the over. The Chiefs' pass defense isn't great, either. They are currently allowing 251.4 passing yards per game to the quarterback position and have yet to face a quarterback or offense as talented as Watson and the Texans.

Watson is currently averaging 272.8 passing yards per game and has superb weapons in DeAndre Hopkins and Will Fuller. The Texans are four-point underdogs in this game and may find themselves in comeback mode at several points throughout the game. If this ends up being the case, Watson should have no problem eclipsing the 300-yard mark. 

Play the Over/Under Contest Now on Monkey Knife Fight

 

Falcons @ Cardinals

Fantasy Challenge Contest

Recommended Prop Pick: Julio Jones, Larry Fitzgerald, and Austin Hooper over 55.5 fantasy points.

For our second contest selection, we go to Arizona where we find the second-highest total on the board of 51.5. Both of these defenses are flat-out awful. Atlanta is currently allowing 31.3 fantasy points per game to wide receivers, which is dead-last in the league. They have allowed 69 receptions for 985 yards and a whopping 10 touchdowns.

Fitzgerald has quickly become Kyler Murray's favorite target as well. He is currently averaging 8.8 targets per game, which he has turned into 71.6 receiving yards per game and two touchdowns. This is the perfect matchup for him and I expect a huge game. The Cardinals are currently giving up over 22 fantasy points per game to the wide receiver position and have allowed six receiving touchdowns to wide receivers.  Julio Jones should be able to exploit the Cardinals secondary without Patrick Peterson and help hit the total.

Lastly, the Cardinals are horrific against the tight end position. They have given up 461 receiving yards, six touchdowns, and an average of 16.4 fantasy points per game to tight ends. These all rank dead-last in the league. Austin Hooper is currently averaging nearly seven receptions per game to go along with 72.6 receiving yards per game. He has become a favorite target of Matt Ryan and should see plenty of looks in this game.

Play the Rush Hour Contest Now on Monkey Knife Fight

 

Seahawks @ Browns

Touchdown Dance Contest

Recommended Prop Pick: Chris Carson, Odell Beckham Jr., and Nick Chubb over 1.5 touchdowns.

The total in this game is not as high as I would have expected at 46, but there is still plenty of opportunity for scoring. The Browns have struggled against the run this year, which was highlighted on Monday Night Football against the 49ers. They are currently giving up 112.2 yards per game to running backs, which means Chris Carson should have ample opportunities to break off a run into the endzone.

Carson has been given 49 carries over the last two weeks and certainly will be given the ball frequently in this game with the hopes of exploiting the Browns struggling run defense. The Seahawks, while a bit stronger vs. the run, have given up four rushing touchdowns on the season. Nick Chubb is currently averaging just under 100 rushing yards per game and has four rushing touchdowns on the season. He should be able to punch at least one more in vs. this Seattle defense.

Lastly, the Seahawks Defense has struggled vs. the pass this season, allowing 793 receiving yards and four touchdowns to the wide receiver position. Odell Beckham was largely uninvolved last week vs the 49ers, which leads me to believe he will be a focal point this week. Beckham rarely goes silent for extended periods, so I look for him to rebound in a big way at home this week.

Play the Fantasy Challenge Contest Now on Monkey Knife Fight

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WR
TE
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DEF

RANKINGS

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DEF

REAL-TIME FANTASY NEWS

Kevin Huerter

is Cleared to Return for Game 5
Caris LeVert

is Available for Game 5 on Wednesday
Duncan Robinson

is Out for Game 5
Keegan Murray

Undergoes Ankle Procedure
Josh Giddey

Undergoes Ankle Surgery
Pete Fairbanks

Returns From Injured List
Christian Yelich

Out With Back Tightness on Wednesday Night
Nathan MacKinnon

Chasing History Wednesday
Ryan Poehling

Won't Be an Option for Game 6
Sam Malinski

Set to Miss Second Straight Game
Artturi Lehkonen

Unlikely to Play Wednesday
Matthew Schaefer

Wins Calder Trophy
TOR

Maple Leafs Fire Head Coach Craig Berube
Jalen Hurts

Can Jalen Hurts Bounce Back as a Rusher in 2026?
Robby Snelling

Placed on 15-Day Injured List with Elbow Sprain
Zach Charbonnet

Dynasty Value in Question Entering 2026
DeVonta Smith

Poised to Reach a New Level of Production in 2026?
Chris Olave

Facing Increased Target Competition in New Orleans Entering 2026
Chris Bell

Dynasty Stock Rising Following NFL Draft
Ted Hurst

Facing Uphill Battle for Playing Time in Tampa Bay
Francisco Alvarez

Mets Place Francisco Alvarez on Injured List With Torn Meniscus
Max Fried

Dealing With Left Elbow Posterior Soreness
CFB

NFL Veteran Tom Moore Joins Iowa Coaching Staff
CFB

Can Cam Cook Dominate in Return to Big 12?
Chris Brazzell II

Is Chris Brazzell II the Top Deep Threat in Carolina's Receiver Room?
Kaelon Black

a Threat to Win Backup RB Job in San Fran?
CFB

ACC, Big 12 Support 24-Team College Football Playoff
De'Zhaun Stribling

to be 49ers' New "F" Receiver?
CFB

Anthony Colandrea Looking to Elevate Nebraska Back to National Contention
Drew Allar

Steelers "Uninstalling" Everything Drew Allar Learned in College
CFB

Kwazi Gilmer Set for Big Impact at Nebraska
Ja'Kobi Lane

Is Ja'Kobi Lane the Pass-Catching Answer the Ravens Have Been Seeking?
Zachariah Branch

Does Zachariah Branch Have a Path to Immediate Production?
Max Klare

Can Max Klare Separate Himself in Rams' Tight End Room?
Eli Stowers

the Tight End of the Future in Philadelphia?
Justin Thomas

Trending Well Ahead of PGA Championship Despite Concerning Form
J.J. Spaun

Trending Up Ahead of PGA Championship
Adam Scott

Riding Strong Form Into PGA Championship
Patrick Reed

Looking to Make Another Run at PGA Championship
PGA

Sungjae Im Looks to Build on Strong Finish at Truist Championship
Sam Burns

Must Keep Ball in Play at PGA Championship
Jordan Spieth

Looks to Complete Career Grand Slam at Aronimink
Brandt Snedeker

Not the Best Option for the PGA Championship
Rasmus Hojgaard

a Volatile Option at PGA Championship
Germie Bernard

Already in a Tough Spot to Hold Dynasty Value
Ayo Dosunmu

Has Busy Night in Game 5
Maverick McNealy

Seeking Better Start in Philadelphia
Harry Hall

a Boom-or-Bust Option at Aronimink
Jaden McDaniels

Notches 17 Points in Game 5 Loss
Denzel Boston

a Smart Bet to Meet or Exceed Value in Dynasty Rookie Drafts
Hideki Matsuyama

Attempts to Improve Over 2025 PGA Championship
Scottie Scheffler

Looks to Defend PGA Championship at Aronimink
Julius Randle

Posts a Double-Double in Losing Effort
Matthew Stafford

a Sell Candidate with Touchdown Regression Likely on its Way
Nicolai Hojgaard

Wants to Keep Momentum Rolling in Philadelphia
Anthony Edwards

Held to 20 Points in Game 5 Loss
Ben Griffin

Attempting to Bounce Back After Truist Championship
CFB

Transfer Defensive Lineman Devarrick Woods Commits to Clemson
Keldon Johnson

Comes Alive in Game 5 Against Timberwolves
Jayden Reed

Dynasty Value Tethered to His Underwhelming Usage
Harris English

Will Need His Putter to Thrive at Aronimink
Stephon Castle

Makes All-Around Impact in Game 5
Kenyon Sadiq

Is Kenyon Sadiq the Next Great Rookie Tight End?
Victor Wembanyama

Leads Spurs to Big Win in Game 5
Akshay Bhatia

Creative Flair Could Show Itself in Philadelphia
Keegan Bradley

Knows the Aronimink Golf Club Well
Mason McTavish

Delivers Two Assists Tuesday Night
Pavel Dorofeyev

Pots Two Goals in Vital Game 5 Win
Josh Doan

Records Two Assists in Game 4 Victory
Evgeni Malkin

Penguins Want Evgeni Malkin Back
Sidney Crosby

Joins Team Canada for World Championship
Ryan Poehling

Suffers Upper-Body Injury in Game 5 Loss
Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
Cade Klubnik

Becoming Fan Favorite, in Play to Win Backup QB Job?
Michael Penix Jr.

Throwing During Offseason Program
Brandon Nimmo

Leaves Game on Tuesday with Apparent Ankle Injury
Philadelphia 76ers

76ers Part Ways With Daryl Morey
Kevin Huerter

Iffy for Game 5 Against Cavaliers
Dylan Harper

Cleared for Action Tuesday
De'Aaron Fox

Available for Game 5 Against Timberwolves
Caris LeVert

Remains on Injury Report With Heel Issue
Duncan Robinson

Listed as Questionable for Game 5
Memphis Grizzlies

Brandon Clarke Dies at Age 29
Charlie McAvoy

Slapped With Six-Game Suspension
Jonas Brodin

Unavailable for Game 5 Against Avalanche
Joel Eriksson Ek

to Remain Out Wednesday
Sam Malinski

Day-to-Day With Upper-Body Injury
Jacob Wilson

A's Place Jacob Wilson on Injured List With Shoulder Subluxation
Artturi Lehkonen

Considered Day-to-Day
Charlie Coyle

Lands Six-Year Extension
Ukko-Pekka Luukkonen

to Start Game 4 Against Canadiens
Drew Helleson

Unavailable for Game 5
Radko Gudas

Still Out Tuesday
Christian Yelich

Brewers Reinstate Christian Yelich From Injured List
Luka Dončić

Luka Doncic Admits He Wasn't Close to Returning Before Season Ended
CFB

Isaac Brown Has All-American Upside in 2026
LeBron James

Uncertain About Future After Season-Ending Loss
CFB

Nyck Harbor Heading into Breakout Year?
CFB

Notre Dame, USC in Discussions to Resume Rivalry Series
CFB

Jaron-Keawe Sagapolutele Has Eyes on ACC Title
CFB

Ahmad Hardy's Gunshot Wound Not Viewed as Career-Threatening
A.J. Ewing

Mets to Call Up Top Prospect A.J. Ewing
Mookie Betts

is Officially Back on Monday
Nathan Eovaldi

Scratched From Monday's Start With Side Tightness
Henry Bolte

Athletics to Promote Top Outfield Prospect Henry Bolte to Major Leagues
Khamzat Chimaev

Suffers his First Loss
Sean Strickland

Recaptures Middleweight Title
Tatsuro Taira

Suffers Fifth-Round TKO Loss
Joshua Van

Defends Flyweight Title
MMA

Waldo Cortes-Acosta Drops Decision
Alexander Volkov

Wins Back-To-Back Fights
Shane Van Gisbergen

Dominates Watkins Glen for First Win of 2026
Michael McDowell

Finishes Second for Best Run of the Year At Watkins Glen
Ty Gibbs

Scores New Career-Best Finish of Third at Watkins Glen
Tyler Reddick

Continues His Strong Season With Fifth-Place Run at Watkins Glen
Austin Dillon

Earns his First Top-10 Finish of 2026 at Watkins Glen
Mookie Betts

Dodgers Expect Mookie Betts to Return on Monday
CFB

Ahmad Hardy Sustains Gunshot Wound, in Stable Condition
Connor Zilisch

Will Start Fifth in his First Watkins Glen Cup Series Race
Tyler Reddick

Is A Top DFS Option for Watkins Glen Lineups
Christopher Bell

Is Likely to Bounce Back This Week at Watkins Glen
Carlos Rodón

Carlos Rodon Activated for Season Debut on Sunday
William Byron

Is William Byron Playable in DFS Lineups at Watkins Glen?
Kyle Larson

May have A Positive Day at Watkins Glen
Chase Briscoe

May Compete for A Top-10 Finish at Watkins Glen
NASCAR

A.J. Allmendinger May have Another Solid Outing at Watkins Glen
Ty Gibbs

Should Fantasy Managers Roster Ty Gibbs at Watkins Glen?
Ross Chastain

Is Ross Chastain Worth Rostering for Watkins Glen Lineups?
Austin Cindric

Could Austin Cindric be A Sneaky Tournament Play for Watkins Glen?
Shane Van Gisbergen

Shane van Gisbergen the Heavy Favorite at Watkins Glen
Chase Elliott

Is Chase Elliott a No-Brainer DFS Pick at Watkins Glen?
Chris Buescher

Qualifies 14th at Watkins Glen
Ryan Blaney

Has Upside at Watkins Glen After Signing Contract Extension
Michael McDowell

Still Searching for First Top-Five Finish at Watkins Glen
Carson Hocevar

Is Carson Hocevar Too Aggressive for Road-Course Racing?
Luis Castillo

Mariners Intend to Piggyback Luis Castillo, Bryce Miller
Logan Webb

Placed on 15-Day Injured List With Knee Bursitis
Bryce Miller

is Set to Return on Wednesday
Jeff Hoffman

Could Return to Closer Role
Taj Bradley

Hits the Injured List With Pectoral Inflammation
Kyle Bradish

has Nice Bounce-Back Performance With 10 K's
Casey Mize

Throws Bullpen on Friday, Return Not Imminent
Sean Strickland

An Underdog At UFC 328
Khamzat Chimaev

Set For UFC 328 Main Event
Tatsuro Taira

Can Become The New Flyweight Champion
Joshua Van

Set For His First Title Defense
Alexander Volkov

Looks To Win Back-To-Back Fights
MMA

Waldo Cortes-Acosta Looks To Extend His Win Streak
CFB

Walker Lyons Could be Go-To Target for Bear Bachmeier
CFB

Ty Benefield a Potential Game-Changer for LSU Defense
CFB

Hayden Lowe Set for Significant Role Following Miami's NFL Departures
CFB

Taylor Wein in Position for Big Season on Oklahoma's Defensive Line
CFB

Rasheem Biles an Instant Impact Player for Texas