X
Lost password?

Don't have an account?
Join the Best Live Fantasy Chat Community!

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


LINEUP RESOURCES

Articles & Tools
Import Your Leagues
Weekly Rankings
Compare Any Players
Starts and Sit
Daily Fantasy
Who To Pickup
Fantasy Updates
24x7 News and Alerts

NFL DFS Lineup Picks for FanDuel, DraftKings - 49ers vs Cardinals MNF Showdown

George Kittle - Fantasy Football Rankings, NFL Injury News, Draft Targets

Happy Monday, RotoBallers! I hope your Week 11 has gone well. I had a great day yesterday, going 4-1 on bets while cashing in all the DFS slates that I played. I'll look to keep the train rolling tonight as we have a short turnaround into a three-game slate on Thanksgiving Thursday. Tonight, though, we'll take a look at an NFC West Showdown as the San Francisco 49ers (5-4) take on the Arizona Cardinals (4-6) in Mexico City. It'll be an interesting slate considering Kyler Murray is a game-time decision in this one, and while it seems like Colt McCoy will end up being the starter in this one, I'll do my best to update should Murray suit up for this one.

We have been pretty successful so far with these showdown slates and hopefully, that trend continues from last year into this year. Most of us started our fantasy journeys with football, so it's always nice when it comes around and it's always a shame for it to come to an end. Thanks to the advanced analytics of today, I'll do my best to provide you with as much in-depth analysis as possible regarding positional matchups and the like to help put some lunch money in your pocket. Let's make some coin this season gang, and let's get right to it. 

I will be providing you with daily fantasy football picks on FanDuel and DraftKings for the 49ers vs Cardinals NFL DFS showdown slate on November 21st. These NFL DFS lineup picks can vary from higher-priced players and elite options to lower-priced players and value picks on both DraftKings and FanDuel. If you have any questions, you can follow me on Twitter @LucidMediaDFS and fire away, or sign up for a premium RotoBaller NFL package and chat with me and other NFL DFS analysts at any time you'd like!

Featured Promo: Get any full-season NFL Premium Pass for 50% off and win big in 2023. Exclusive access to our Premium articles, 15 lineup tools, new Team Sync platform, Lineup Optimizer, Premium DFS tools and cheat sheets, and much more! Sign Up Now!

 

MVP/Captain Plays

Christian McCaffrey - RB, $17,100 (DK), $16,500 (FD)

Key Stats

  • 2022 Stats: 125 rushes, 563 rushing yards, 60 targets, 47 receptions, 395 rushing yards, seven touchdowns.
  • 2022 Offensive Rush DVOA: -8.9% (23rd), per Football Outsiders.
  • 2022 Opposing Defense Rush DVOA: -4.5% (16th), per Football Outsiders.

I'll start off tonight's slate with Christian McCaffery. I'll make it clear that I'm not picking McCaffery with the thought that he's going to light it up on the ground tonight. While the 49ers are 8.5-point favorites, the game script could lead to a breakout spot for him on the ground, and I'd have to assume that he'll end up splitting carries with Elijah Mitchell. With that said, the 49ers do have a projected 41.47% DVOA to running backs in the passing game, so I project CMC to do the majority of his damage in the passing game.

Jimmy Garoppolo - QB, $14,400 (DK), $14,500 (FD)

Key Stats

  • 2022 Stats: 1,931 passing yards, 11 touchdowns, four interceptions.
  • 2022 Offensive Pass DVOA: 23.3% (7th), per Football Outsiders.
  • 2022 Opposing Defense Pass DVOA: 8.2% (19th), per Football Outsiders.

Throwing CMC the ball will be Jimmy Garoppolo. I've mentioned in previous articles that Garoppolo isn't the "ideal" fantasy quarterback. However, the 49ers do have a relative passing funnel tonight -- with a projected pass DVOA of 22.11% and a projected rush DVOA of -10.09%. My model projects Jimmy G to complete 72.24% of his pass attempts tonight for 273.44 yards and 1.99 touchdowns. He's cheaper than your typical QB on a showdown slate, and that's why I have him slated in here.

Other Captains/MVPs: George Kittle, DeAndre Hopkins, 49ers D/ST

 

Want more NFL DFS tools and content? Our NFL Premium package includes our DFS Cheat Sheets, Research Station, Lineup Optimizer, access to our Premium Slack Chatrooms where members can chat with our NFL analysts, and so much more. Check out this big win from RotoBaller's RealTalkRaph using our Premium tools - join in on the winning!

 

DFS Flex Plays

DeAndre Hopkins - WR, $10,400 (DK), $15,000 (FD)

Key Stats

  • 2022 Stats: 46 targets, 36 receptions, 396 receiving yards, two touchdowns.
  • Individual Matchup (vs Deommodore Lenoir): 17% targets per route, 79% catch rate, 0.29 fantasy points per route, per PFF.

On the other side of the field, we have DeAndre Hopkins. I mentioned at the top of the article that Kyler Murray is a game-time decision for this one. Fortunately, Hopkins is seemingly QB-proof. He's logged at least 13 targets in three of his first four games since returning from suspension and hauled in 10 of his 14 targets for 98 yards last Sunday while Colt McCoy was under center. Hopkins is a bit too pricy for me on FanDuel, but I love him in this spot on DraftKings.

George Kittle - TE, $7,000 (DK), $10,000 (FD)

Key Stats

  • 2022 Stats: 41 targets, 29 receptions, 340 receiving yards, two touchdowns.
  • Individual Matchup (vs Isaiah Simmons): 12% targets per route, 89% catch rate, 0.24 fantasy points per route, per PFF.

One player that I absolutely LOVE on both sites tonight is George Kittle. The Cardinals have a projected 41.57% DVOA against tight ends in this matchup, and Kittle has a strong matchup advantage against Isaiah Simmons, according to PFF. My model projects Kittle to grab 6.21 of his 6.95 targets tonight for 70.33 yards and a 59% chance of scoring a touchdown. He's certainly an option in the 1.5x spot and he'll be in most if not all of my lineups.

Other Flex Options: Colt McCoy, Deebo Samuel, Brandon Aiyuk, Rondale Moore

 

DFS Value Plays

San Francisco 49ers - D/ST, $5,000 (DK), $9,500 (FD)

Key Stats

  • 2022 Stats: 17.66 targets, 29 sacks, seven interceptions, three fumble recoveries, two defensive touchdowns.
  • Projected DVOA: -22.22%

If there's any indication by now I'm writing this up, I'll be heavy 49ers on this slate tonight. If you're making a 49ers "stack," you'll want to have the defense in there as well. The 49ers project to an 8.94% sack rate tonight and a projected -26.84% defensive rushing DVOA. With that said, I do like this play a lot more if it's Colt McCoy under center, with the Niners not allowing the Cardinals to lean on the run game while putting consistent pressure on McCoy. I favor them regardless of who plays quarterback for Arizona tonight, but I'll give them a definite boost if it's McCoy.

Kyle Juszczyk - RB, $600 (DK), $5,000 (FD)

Key Stats

  • 2022 Stats: Three rushes, 10 rushing yards, 15 targets, 11 receptions, 153 rushing yards, one touchdown.
  • 2022 Offensive Rush DVOA: -8.9% (23rd), per Football Outsiders.
  • 2022 Opposing Defense Rush DVOA: -4.5% (16th), per Football Outsiders.

Last but not least, I'll finish things up with Kyle Juszczyk. Certainly a dart throw here, but he's just too cheap considering the upside he brings to the table. I mentioned when talking about CMC that the 49ers have a projected 41.47% passing DVOA when targeting running backs, and all we need is one reception that Juszczyk takes into the end zone for him to break the slate.

Other Value Plays: Elijah Mitchell, A.J. Green, Robbie Gould, Matt Prater

Enjoy your week and good luck everyone!



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!




Win Big With RotoBaller

Be sure to also check out all of our other daily fantasy football articles and analysis to help you set those winning lineups, including this new RotoBaller YouTube video:

More Weekly DFS Analysis

LINEUP RESOURCES

Articles & Tools
Import Your Leagues
Weekly Rankings
Compare Any Players
Starts and Sit
Daily Fantasy
Who To Pickup
Fantasy Updates
24x7 News and Alerts

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

ROTOBALLER PLAYER NEWS

Zach Wilson9 hours ago

Jets Have No Plans To Trade Zach Wilson
Seth Curry9 hours ago

Will Be Sidelined On Monday Versus Clippers
Kyle Kuzma9 hours ago

Ruled Out On Monday With Sprained Ankle
Cleveland Browns9 hours ago

Myles Garrett Dislocates Toe At Pro Bowl Games
Bradley Beal9 hours ago

Uncertain To Play On Monday Versus Cleveland
Isaiah Stewart9 hours ago

Questionable Against Boston On Monday
Drew Eubanks10 hours ago

Likely To Suit Up On Monday
Gary Payton10 hours ago

II Probable To Play On Monday
Kyle Anderson10 hours ago

Exits Sunday's Game With Back Spasms
Kyle Anderson13 hours ago

Playing On Sunday
Rudy Gobert13 hours ago

Starting Against Denver
RJ Barrett13 hours ago

Ruled Out Right Before Tip Off
Jordan McLaughlin13 hours ago

Will Play On Sunday
Brandon Ingram13 hours ago

Out With Toe Soreness
Jonas Valanciunas13 hours ago

Out Sunday, Avoids Serious Injury
Joel Embiid14 hours ago

Starting Against Knicks
Jaren Jackson14 hours ago

Jr. Playing Sunday
Ja Morant14 hours ago

Officially Out Against Raptors
Dorian Finney-Smith16 hours ago

On The Move To Brooklyn
Stephen Curry16 hours ago

To Miss Multiple Weeks
Spencer Dinwiddie16 hours ago

Returning To Brooklyn
Kyrie Irving16 hours ago

Heading To Dallas
Jordan Romano18 hours ago

Won't Pitch In World Baseball Classic
Jamal Murray18 hours ago

Doubtful Versus Minnesota
Nick Plummer18 hours ago

Reds Sign Nick Plummer
Chad Kuhl18 hours ago

Nationals Add Chad Kuhl On Minor-League Deal
Jake Faria18 hours ago

Red Sox Sign Jake Faria To Minor-League Deal
Bobby Witt Jr.18 hours ago

Royals Exploring Extensions For Bobby Witt Jr., Others
Logan Webb18 hours ago

Giants Discussing Extension With Logan Webb
Miguel Rojas19 hours ago

Dodgers, Miguel Rojas Agree On Two-Year Deal
Max Fried19 hours ago

Loses Arbitration Case
Joey Logano21 hours ago

Facing Different Reality At Los Angeles
Ross Chastain21 hours ago

And The Clash On Sunday
Ty Gibbs21 hours ago

Has To Race Into Coliseum Main Event
Kyle Larson22 hours ago

Bit Of A Wildcard At Los Angeles
Alex Bowman22 hours ago

Qualified Ninth At Los Angeles
NASCAR22 hours ago

A.J. Allmendinger Has Exciting Saturday At Coliseum
Denny Hamlin22 hours ago

Starts Second In Heat Three At Coliseum
Austin Dillon22 hours ago

Continues Chevy Theme In Los Angeles
Aric Almirola22 hours ago

Rises To Fifth In Qualifying Saturday
William Byron22 hours ago

Qualifies Fourth For Sunday At Los Angeles
Christopher Bell22 hours ago

Surprises Some At Coliseum Saturday
Kyle Busch22 hours ago

Loves Los Angeles Again On Saturday
Justin Haley23 hours ago

Heats Up Coliseum Track Saturday
Josh Jacobs1 day ago

Won't Settle In Extension Talks
Aleksander Barkov2 days ago

Riding A Career-High Point Streak
Steven Stamkos2 days ago

On An 11-Game Point Streak
Sebastian Aho2 days ago

Enjoying Career-Best Goal Streak
Connor McDavid2 days ago

On Track For A 150-Point Campaign
Jake DeBrusk2 days ago

Ready To Return After The Break
Bowen Byram2 days ago

Expected To Be Back After The Break
Matthew Tkachuk2 days ago

Voted MVP At The All-Star Game
Fernando Tatis Jr.2 days ago

Open To Any Position
Luke Williams2 days ago

Dodgers Re-Sign Luke Williams To Minor-League Deal
Nolan Blackwood2 days ago

Twins Sign Nolan Blackwood
Jake McGee2 days ago

Announces His Retirement
Juan Minaya2 days ago

Pirates Sign Juan Minaya To Minor-League Deal
Yusniel Diaz2 days ago

Dodgers Sign Yusniel Diaz To Minor-League Deal
Franklin German2 days ago

White Sox Acquire Franklin German From Red Sox
Aaron Sanchez2 days ago

Twins Re-Sign Aaron Sanchez
Mecole Hardman3 days ago

Doubtful For Super Bowl
JuJu Smith-Schuster3 days ago

Kadarius Toney Questionable
Miguel Sanó3 days ago

Miguel Sano Hosting Workout Next Week
DL Hall3 days ago

Orioles Want DL Hall To Start
Anthony Misiewicz3 days ago

DFA'd By Royals
Eguy Rosario3 days ago

Out Until Summer With Broken Ankle
Jesús Luzardo3 days ago

Jesus Luzardo Wins Arbitration Case Over Marlins
Derek Carr3 days ago

Won't Extend Contract Trigger Date
Derek Carr3 days ago

Expected To Draw Plenty Of Interest
Aaron Rodgers3 days ago

: "I'm Not Going To San Fran"
Joe Mixon3 days ago

Charges Against Joe Mixon Will Be Dropped
Joe Mixon4 days ago

Has Warrant For Arrest
Mecole Hardman4 days ago

Unlikely To Play In Super Bowl
Mark Stone4 days ago

Out Indefinitely Following Back Surgery
Mitchell Marner4 days ago

Reaches 60 Points With Wednesday's Goal
Charlie Coyle4 days ago

Hands Out Two Assists
Alex Tuch4 days ago

Scores Only Sabres Goal In Wednesday's Defeat
Jesperi Kotkaniemi4 days ago

Picks Up Two Assists Against Buffalo
Tage Thompson4 days ago

Exits With Injury
Antti Raanta4 days ago

Shuts Down Sabres Wednesday
Stefan Noesen4 days ago

Picks Up Two Points In Victory
Pavel Zacha4 days ago

Scores Twice In Bruins Win
David Krejci4 days ago

Pockets Assist Wednesday
Jimmy Garoppolo5 days ago

Will Not Return To 49ers Next Season
Gustav Nyquist5 days ago

Set To Miss Rest Of The Season
Linus Ullmark5 days ago

Tries To End A Losing Run Wednesday
Ilya Samsonov5 days ago

Chases Another Home Win
Mattias Samuelsson5 days ago

Available Again Wednesday
Tua Tagovailoa5 days ago

Clears The Concussion Protocol
Dak Prescott5 days ago

Cowboys Open To Extension For Dak Prescott
Daniel Jones5 days ago

Giants Want To Re-Sign Daniel Jones
Justin Fields5 days ago

Bears Sticking With Justin Fields; Set To Trade First Pick?
MMA5 days ago

Sergey Spivak Can Earn A Big Victory Saturday
Derrick Lewis5 days ago

Looking For First Win Since 2021
Devin Clark5 days ago

Hoping To Turn Things Around
MMA5 days ago

Jung Da Un Set For Big Co-Main-Event Spotlight
Will Gordon5 days ago

In The Field At Pebble Beach
Thomas Detry5 days ago

Set For Pebble Beach Debut
Blagoy Ivanov5 days ago

Hoping For Big Start To 2023
MMA5 days ago

Marcin Tybura Set To Improve No. 10 Ranking If Victorious
Jordan Spieth5 days ago

Always An Option At Pebble Beach
Kyle Nelson5 days ago

Hoping To Prevent Three-Fight Losing Streak
MMA5 days ago

Choi Doo-ho Returns To Action After Layoff
Viktor Hovland5 days ago

Set To Play At Pebble Beach
Maverick McNealy5 days ago

A Nice Option At Pebble Beach
Tom Brady5 days ago

Announces Retirement From The NFL
Lamar Jackson6 days ago

Likely To Be Franchise Tagged
Houston Texans6 days ago

Texans Hire DeMeco Ryans As Head Coach
Denver Broncos6 days ago

Broncos Acquire Sean Payton As Next Head Coach
Ben Griffin6 days ago

Set To Make AT&T Pebble Beach Pro-Am Debut
Beau Hossler6 days ago

Looks To Repeat Success At Pebble Beach
Kurt Kitayama6 days ago

Searching For Form
Russell Knox6 days ago

Looks To Stay Consistent At Pebble Beach
PGA6 days ago

Matt Fitzpatrick An Elite Fantasy Option At Pebble Beach
Adam Fugitt6 days ago

Set For A Very Tough Test
Yusaku Kinoshita6 days ago

Japanese Finisher Yusaku Kinoshita Set For UFC Debut
Taylor Pendrith6 days ago

Seeking Better Fortune At Pebble Beach
Justin Lower6 days ago

Sets Up Well For Pebble Beach
Davis Riley6 days ago

Not On Many Radars For Pebble Beach
Matthew NeSmith6 days ago

Trying To Turn Back Clock At Pebble Beach
Justin Rose6 days ago

Needs To Avoid Mistakes At Pebble Beach