👉 TAP TO SAVE 50% WITH CODE SPRING
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Draft Rankings
Draft Simulator
Compare Any Players
24x7 News and Alerts

NFL DFS: DraftKings, FanDuel SNF 49ers vs. Bills Daily Fantasy Football Picks - Sunday Night Showdown Slate (Week 13)

Five Fantasy Football Overvalued Quarterbacks

Tonight's top NFL DFS lineup picks for DraftKings, FanDuel -- 49ers vs. Bills SNF showdown slate Week 13 (Dec. 1, 2024). John's NFL daily fantasy sleeper picks.

Welcome back, RotoBallers! We have a fun Sunday Night Football as Brock Purdy and the San Francisco 49ers (5-6) travel east to take on Josh Allen and the Buffalo Bills (9-2). As the Bills look to keep pace with the Kansas City Chiefs atop the AFC, the 49ers fight for their playoff lives in a tight NFC West race. Let’s see how this one plays out. 

Thanks to today's advanced analytics, I'll do my best to provide you with as much in-depth analysis as possible regarding positional matchups and the like to help put some lunch money in your pocket. Let's make some coin this season, gang, and get right to it.

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

I will provide you with daily fantasy football picks on FanDuel and DraftKings for the 49ers vs. Bills Sunday night NFL DFS showdown slate on December 1st. These NFL DFS lineup picks can vary from higher-priced players and elite options to lower-priced players and value picks. For questions, follow me on X @LucidMediaDFS, or sign up for RotoBaller premium to chat any time!

 

MVP/Captain - NFL DFS Lineup Picks

James Cook - RB, $14,400 (DK), $13,000 (FD)

Key Stats

  • 2024 Stats: 137 rushing attempts, 596 rushing yards, 31 targets, 25 receptions, 182 receiving yards, 11 touchdowns. 
  • Projected Rush DVOA: 9.91%

I’ll start tonight’s slate off with the guy who has the best matchup of the night, James Cook. San Francisco is banged up, and it’s been reported that star linebacker Fred Warner has been playing most of this season on a fractured ankle. There’s no doubt that this contributes to the 49ers 21st-ranked rushing defense. 

My model projects Cook to run for 65.57 yards on 14.5 attempts while adding 2.24 receptions for 16.37 yards on 3.4 targets. 

Khalil Shakir - WR, $12,000 (DK), $11,000 (FD)

Key Stats

  • 2024 Stats: 66 targets, 56 receptions, 599 receiving yards, two touchdowns. 
  • Opponent DVOA vs. WR2: 28.3%

While it’s my opinion that the Bills will use the ground game to control the direction this game goes, there will be plenty of opportunities for Josh Allen and his pass-catchers. Shakir has the best matchup of any Buffalo pass-catchers, as San Francisco ranks 27th against opposing teams’ second receivers. 

My model projects Shakir 5.2 of his 6.6 targets for 55.74 yards and 0.3 touchdowns. Each of these numbers represents the highest projection among the Buffalo receiving corps, and he’s a solid option in the captain/MVP spot.

Other Captains/MVPs: George Kittle, Josh Allen, Christian McCaffrey, Brock Purdy

Win more with expert tools and advice from proven winners. A valued RotoBaller Premium subscriber won half a MILLION dollars in Week 3! Join in on the winning and get your edge with our NFL Premium Pass, which includes our exclusive DFS Cheat Sheets, the #1 Lineup Optimizer, and access to our VIP Chatrooms. RotoBaller's Premium Pass comes with a 100% money-back guarantee. Gain access now!

this is my community.. this is my family.. without them this would not happen @WinDailySports @RotoBaller@BaronZito973 @mb_guruDFS #OTC there are others and you know who you are and I love you all for the help! pic.twitter.com/psRCDbCqqL

— Scott (@scottd923) September 25, 2023

 

Flex Plays - NFL DFS Lineup Picks

Josh Allen - QB, $11,000 (DK), $16,000 (FD)

Key Stats

  • 2024 Stats: 2,543 passing yards, 18 passing touchdowns, five interceptions, 67 rushing attempts, 316 rushing yards, and five rushing touchdowns. 
  • Projected Pass DVOA: 14.84%

I’ll start with the current MVP favorite, Josh Allen, as we move into our flex options. Allen has been excellent in 2024, no different than previous seasons. Much like the rest of the league, Buffalo has shifted towards a balanced offense, utilizing running backs Cook and Ray Davis to move the ball down the field. Allen still answers the bell when called upon, and I expect more of the same tonight. 

My model projects Allen to throw for 225.48 yards and 1.6 touchdowns while adding 30.29 yards and 0.45 touchdowns with his legs. Despite being the highest-projected player on the slate, I prefer the likes of Shakir and Cook in the captain/MVP spot for salary reasons and the limited ceiling Allen provides due to my projected game script. 

Jauan Jennings - WR, $7,400 (DK), $10,500 (FD)

Key Stats

  • 2024 Stats: 65 targets, 47 receptions, 628 receiving yards, and four touchdowns.
  • Opponent DVOA vs. WR2: 15.3%

I’ll flip the field and look at my first San Francisco player of the night, Jauan Jennings. Jennings draws the strongest matchup in the 49ers offense. It’s anticipated that Purdy will be under center for the 49ers tonight, and Jennings continues to be a strong and reliable option for Purdy in the passing game. He’s caught 15 of his 18 targets in the last two games with Purdy. 

My model projects Jennings to catch 4.79 of his 6.92 targets for 55.59 yards and 0.37 touchdowns. 

Other Flex Options: Christian McCaffrey, Brock Purdy, Amari Cooper, George Kittle

 

Value Plays - NFL DFS Lineup Picks

Jake Moody - K, $5,200 (DK), $8,500 (FD)

Key Stats

  • 2024 Stats: 18/22 field goals made/attempted, 17/17 extra points made/attempted.

I’ll stick with the San Francisco side as we head into our value options. Jake Moody is a good start. I believe that the San Francisco offense can do enough to move the ball against this seventh-ranked Bills defense, at the very least.

However, the question remains what Kyle Shanahan’s offense will do on the Buffalo cold on the Bills’ side of the field? I’m projecting there will be multiple instances where the Niners will have to settle for a field goal, giving Moody a solid floor. 

Dawson Knox - TE, $4,000 (DK), $7,000 (FD)

Key Stats

  • 2024 Stats: 22 targets, 14 receptions, 182 receiving yards, one touchdown.
  • Opponent DVOA vs. TE: -10.3%

I’ll wrap things up with Dawson Knox. Knox will see most of the tight-end snaps in this one as Dalton Kincaid misses his second straight game with a knee injury. Knox did well in his escalated role last week, catching four of six targets for 40 yards against the Chiefs. 

Tonight, my model projects Knox to catch 3.96 of his 5.29 targets for 39.03 yards and 0.41 touchdowns. He is the best value option on the slate and will likely be the highest-owned. I do find this “chalk” to be worth it, and I won’t be missing out here. 

Other Value Options: Ty Johnson, Ricky Pearsall, Ray Davis, Bills D/ST

Enjoy the rest of your weekend, and good luck, everyone! 



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Weekly DFS Analysis




POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Draft Rankings
Draft Simulator
Compare Any Players
24x7 News and Alerts

RANKINGS

QB
RB
WR
TE
K
DEF

RANKINGS

QB
RB
WR
TE
K
DEF

REAL-TIME FANTASY NEWS

Mookie Betts

is Officially Back on Monday
Nathan Eovaldi

Scratched From Monday's Start With Side Tightness
Mark Jankowski

Signs Two-Year Extension With Hurricanes
Joel Kiviranta

Cleared to Play Monday
Josh Manson

Available for Game 4 Monday
Mackenzie Blackwood

Expected to Start Monday
Jonas Brodin

Won't Play Monday
Joel Eriksson Ek

Remains Out Monday
Justin Jefferson

Dynasty Stock on the Rise With New QB in Minnesota
J.J. McCarthy

Injuries, QB Addition in Minnesota Deal Big Blow to J.J. McCarthy's Dynasty Value
Aaron Rodgers

Doesn't Meet With Steelers Over the Weekend
Chris Boswell

Steelers Agree With Kicker Chris Boswell on Four-Year Extension
Henry Bolte

Athletics to Promote Top Outfield Prospect Henry Bolte to Major Leagues
Khamzat Chimaev

Suffers his First Loss
Sean Strickland

Recaptures Middleweight Title
Tatsuro Taira

Suffers Fifth-Round TKO Loss
Harold Fannin Jr.

Offers Tantalizing Dynasty Upside Despite Uncertain Offense
Joshua Van

Defends Flyweight Title
Dalton Kincaid

Is Dalton Kincaid's Long-Term Dynasty Upside Fading Due to Health Concerns?
MMA

Waldo Cortes-Acosta Drops Decision
Alexander Volkov

Wins Back-To-Back Fights
Jordan James

Could Emerge as a Must-Roster Handcuff Option for Dynasty Managers
Jaylen Waddle

Dynasty Stock Rising After Offseason Move to Denver
Josh Downs

in Line for Expanded Role in Indianapolis
Shane Van Gisbergen

Dominates Watkins Glen for First Win of 2026
Mike Evans

Could Be Well-Positioned for a Resurgent Season in San Francisco
Michael McDowell

Finishes Second for Best Run of the Year At Watkins Glen
Ty Gibbs

Scores New Career-Best Finish of Third at Watkins Glen
Tyler Reddick

Continues His Strong Season With Fifth-Place Run at Watkins Glen
Austin Dillon

Earns his First Top-10 Finish of 2026 at Watkins Glen
Ameer Abdullah

Jaguars Sign Running Back Ameer Abdullah for Backfield Depth
Mookie Betts

Dodgers Expect Mookie Betts to Return on Monday
NFL

Ahmad Hardy in Stable Condition After Suffering Gunshot Wound on Sunday
CFB

Ahmad Hardy Sustains Gunshot Wound, in Stable Condition
Kayshon Boutte

in a Likely No-Win Scenario for 2026
Anthony Edwards

Powers Wolves to Game 4 Win
Tetairoa McMillan

Can Tetairoa McMillan Become a Dynasty Cornerstone?
De'Aaron Fox

Posts 24 Points as Spurs Drop Game 4 to Wolves
Justin Herbert

One of Fantasy's Biggest Offseason Winners
Victor Wembanyama

Ejected in Game 4 Loss
VJ Edgecombe

Struggles with Shot in Game 4
Oronde Gadsden

Breakout Chances Dealt a Serious Blow
Paul George

Held to Seven Points in 76ers' Game 4 Loss
David Njoku

Signing With Chargers on One-Year Deal
Josh Hart

Helps Knicks Reach East Finals
Jalen Brunson

Finishes Game 4 Sweep with 22 Points
Rasmus Dahlin

Records Two Points in Game 3 Loss
Tage Thompson

Comes Alive in Game 3 Against Canadiens
Cole Caufield

Ends Dry Spell Sunday
Alex Newhook

Nets Two More Goals in Sunday's Victory
Mitchell Marner

Notches Three Assists in Losing Effort
Beckett Sennecke

Extends Goal Streak to Three Games
Cutter Gauthier

Records Hat Trick of Assists in Game 4 Win
Ashton Jeanty

a Top-Five Dynasty RB Despite Disappointing Rookie Campaign
Devin Neal

the Potential RB2 in New Orleans in his Sophomore Season
Ricky Pearsall

Does Ricky Pearsall Still Have Breakout Potential for Fantasy Managers?
Tory Horton

Dynasty Stock on the Decline Despite Big-Play Ability
Karl-Anthony Towns

Logs Sixth Double-Double of Postseason
Mike Conley

Ayo Dosunmu Replaces Mike Conley in Starting Unit Sunday
Miles McBride

Tallies Game-High 25 Points in Series-Clincher
Tyrese Maxey

Settles for 17 Points Sunday
Joel Embiid

Scores Efficient 24 Points in Season-Ending Loss
Caris LeVert

Iffy for Monday Night
Kevin Huerter

Listed as Questionable for Game 4
Auston Matthews

Uncertain About Future With Maple Leafs
Frederik Andersen

Enjoying Special Postseason
Josh Manson

"Close" to Returning
Joel Kiviranta

Could Return to Action Monday
Radko Gudas

a Game-Time Call Sunday
Mark Stone

Unavailable Sunday
Connor Zilisch

Will Start Fifth in his First Watkins Glen Cup Series Race
Tyler Reddick

Is A Top DFS Option for Watkins Glen Lineups
Christopher Bell

Is Likely to Bounce Back This Week at Watkins Glen
Carlos Rodón

Carlos Rodon Activated for Season Debut on Sunday
William Byron

Is William Byron Playable in DFS Lineups at Watkins Glen?
Austin Reaves

Nears Double-Double In Game 3 Loss
LeBron James

Facing Sweep With Game 4 on Monday
Ajay Mitchell

Posts Career Playoff Night in Game 3
Chet Holmgren

Helps Thunder Move to Brink of Conference Finals
Tobias Harris

Extends 20-Point Streak in Saturday's Loss
Evan Mobley

Keeps Defensive Production Rolling Saturday
Golden State Warriors

Warriors Extend Steve Kerr into his 13th Season
Kyle Larson

May have A Positive Day at Watkins Glen
Chase Briscoe

May Compete for A Top-10 Finish at Watkins Glen
NASCAR

A.J. Allmendinger May have Another Solid Outing at Watkins Glen
Ty Gibbs

Should Fantasy Managers Roster Ty Gibbs at Watkins Glen?
Ross Chastain

Is Ross Chastain Worth Rostering for Watkins Glen Lineups?
Austin Cindric

Could Austin Cindric be A Sneaky Tournament Play for Watkins Glen?
Shane Van Gisbergen

Shane van Gisbergen the Heavy Favorite at Watkins Glen
Chase Elliott

Is Chase Elliott a No-Brainer DFS Pick at Watkins Glen?
Chris Buescher

Qualifies 14th at Watkins Glen
Ryan Blaney

Has Upside at Watkins Glen After Signing Contract Extension
Michael McDowell

Still Searching for First Top-Five Finish at Watkins Glen
Carson Hocevar

Is Carson Hocevar Too Aggressive for Road-Course Racing?
Luis Castillo

Mariners Intend to Piggyback Luis Castillo, Bryce Miller
Logan Webb

Placed on 15-Day Injured List With Knee Bursitis
Bryce Miller

is Set to Return on Wednesday
Jeff Hoffman

Could Return to Closer Role
CHI

Blackhawks Bring in Roman Kantserov for Next Season
Mason McTavish

Set to Rejoin Ducks Lineup Sunday
Taj Bradley

Hits the Injured List With Pectoral Inflammation
Kyle Bradish

has Nice Bounce-Back Performance With 10 K's
Casey Mize

Throws Bullpen on Friday, Return Not Imminent
Ronald Acuña Jr.

Ronald Acuna Jr. Optimistic About Returning Next Wednesday
Tyler Glasnow

Dodgers Put Tyler Glasnow on Injured List With Back Spasms
Blake Snell

to Make Season Debut for Dodgers on Saturday
Cole Ragans

Royals Place Cole Ragans on Injured List With Elbow Impingement
Sean Strickland

An Underdog At UFC 328
Khamzat Chimaev

Set For UFC 328 Main Event
Tatsuro Taira

Can Become The New Flyweight Champion
Joshua Van

Set For His First Title Defense
Alexander Volkov

Looks To Win Back-To-Back Fights
MMA

Waldo Cortes-Acosta Looks To Extend His Win Streak
Nick Lodolo

Officially Activated, Making Season Debut on Friday
CFB

Walker Lyons Could be Go-To Target for Bear Bachmeier
CFB

Ty Benefield a Potential Game-Changer for LSU Defense
CFB

Hayden Lowe Set for Significant Role Following Miami's NFL Departures
CFB

Taylor Wein in Position for Big Season on Oklahoma's Defensive Line
CFB

Rasheem Biles an Instant Impact Player for Texas
Roman Anthony

Heading for the Injured List
CFB

Sam Leavitt Expected to Be Full-Go for Fall Camp
Tarik Skubal

Could Return in 4-6 Weeks After Successful Elbow Surgery
Cole Ragans

Royals Hopeful That Cole Ragans Makes his Next Start
Emilio Pagán

Emilio Pagan has Grade 2 Hamstring Strain, Expected to Miss 4-8 Weeks
CFB

Brauntae Johnson the Next Star in Notre Dame's Secondary?
CFB

Ethan Barbour a Name to Know in Georgia's Tight End Room
CFB

Payton Pierce Next Up at Linebacker for Ohio State
CFB

Javin Gordon to Play Significant Role for Tennessee?
CFB

Tanook Hines Stepping into WR1 Role for USC
CFB

Rueben Owens II has "Star Potential" in Fourth Campaign
Collin Morikawa

Withdraws From Truist Championship
Xander Schauffele

Carries Elite Form Into Quail Hollow
Hideki Matsuyama

Looks to Bounce Back at Truist Championship
Matt Fitzpatrick

Secures Third Win of 2026 Season
Patrick Cantlay

Continues Playing Well Heading to Truist Championship
Ludvig Aberg

Returns to Action For Truist Championship
Justin Thomas

Searching for Consistency at Quail Hollow
Jordan Spieth

Looks to Break Through at Quail Hollow
Adam Scott

Brings Strong Form to Quail Hollow
Robert MacIntyre

a Steady Option at Truist Championship
Jason Day

Looks to Overcome Approach Struggles at Quail Hollow
Akshay Bhatia

Looks for Complete Game at Truist Championship
Justin Rose

to Continue Mid-Season Club Change at Truist Championship
Si Woo Kim

is Back to Peak Form Ahead of Truist Championship
Sam Burns

to Bounce Back at Truist Championship
Cameron Young

Looks to Carry Dominance to Quail Hollow