👉 TAP TO SAVE 30% WITH CODE NEW
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

NFL DFS: DraftKings, FanDuel SNF 49ers vs. Bills Daily Fantasy Football Picks - Sunday Night Showdown Slate (Week 13)

Five Fantasy Football Overvalued Quarterbacks

Tonight's top NFL DFS lineup picks for DraftKings, FanDuel -- 49ers vs. Bills SNF showdown slate Week 13 (Dec. 1, 2024). John's NFL daily fantasy sleeper picks.

Welcome back, RotoBallers! We have a fun Sunday Night Football as Brock Purdy and the San Francisco 49ers (5-6) travel east to take on Josh Allen and the Buffalo Bills (9-2). As the Bills look to keep pace with the Kansas City Chiefs atop the AFC, the 49ers fight for their playoff lives in a tight NFC West race. Let’s see how this one plays out. 

Thanks to today's advanced analytics, I'll do my best to provide you with as much in-depth analysis as possible regarding positional matchups and the like to help put some lunch money in your pocket. Let's make some coin this season, gang, and get right to it.

Featured Promo: Looking for some more fantasy football action? Adopt a dynasty orphan team over at FFPC. Sign up today and get $25 off any FFPC league. Sign Up Now!

I will provide you with daily fantasy football picks on FanDuel and DraftKings for the 49ers vs. Bills Sunday night NFL DFS showdown slate on December 1st. These NFL DFS lineup picks can vary from higher-priced players and elite options to lower-priced players and value picks. For questions, follow me on X @LucidMediaDFS, or sign up for RotoBaller premium to chat any time!

 

MVP/Captain - NFL DFS Lineup Picks

James Cook - RB, $14,400 (DK), $13,000 (FD)

Key Stats

  • 2024 Stats: 137 rushing attempts, 596 rushing yards, 31 targets, 25 receptions, 182 receiving yards, 11 touchdowns. 
  • Projected Rush DVOA: 9.91%

I’ll start tonight’s slate off with the guy who has the best matchup of the night, James Cook. San Francisco is banged up, and it’s been reported that star linebacker Fred Warner has been playing most of this season on a fractured ankle. There’s no doubt that this contributes to the 49ers 21st-ranked rushing defense. 

My model projects Cook to run for 65.57 yards on 14.5 attempts while adding 2.24 receptions for 16.37 yards on 3.4 targets. 

Khalil Shakir - WR, $12,000 (DK), $11,000 (FD)

Key Stats

  • 2024 Stats: 66 targets, 56 receptions, 599 receiving yards, two touchdowns. 
  • Opponent DVOA vs. WR2: 28.3%

While it’s my opinion that the Bills will use the ground game to control the direction this game goes, there will be plenty of opportunities for Josh Allen and his pass-catchers. Shakir has the best matchup of any Buffalo pass-catchers, as San Francisco ranks 27th against opposing teams’ second receivers. 

My model projects Shakir 5.2 of his 6.6 targets for 55.74 yards and 0.3 touchdowns. Each of these numbers represents the highest projection among the Buffalo receiving corps, and he’s a solid option in the captain/MVP spot.

Other Captains/MVPs: George Kittle, Josh Allen, Christian McCaffrey, Brock Purdy

Win more with expert tools and advice from proven winners. A valued RotoBaller Premium subscriber won half a MILLION dollars in Week 3! Join in on the winning and get your edge with our NFL Premium Pass, which includes our exclusive DFS Cheat Sheets, the #1 Lineup Optimizer, and access to our VIP Chatrooms. RotoBaller's Premium Pass comes with a 100% money-back guarantee. Gain access now!

this is my community.. this is my family.. without them this would not happen @WinDailySports @RotoBaller@BaronZito973 @mb_guruDFS #OTC there are others and you know who you are and I love you all for the help! pic.twitter.com/psRCDbCqqL

— Scott (@scottd923) September 25, 2023

 

Flex Plays - NFL DFS Lineup Picks

Josh Allen - QB, $11,000 (DK), $16,000 (FD)

Key Stats

  • 2024 Stats: 2,543 passing yards, 18 passing touchdowns, five interceptions, 67 rushing attempts, 316 rushing yards, and five rushing touchdowns. 
  • Projected Pass DVOA: 14.84%

I’ll start with the current MVP favorite, Josh Allen, as we move into our flex options. Allen has been excellent in 2024, no different than previous seasons. Much like the rest of the league, Buffalo has shifted towards a balanced offense, utilizing running backs Cook and Ray Davis to move the ball down the field. Allen still answers the bell when called upon, and I expect more of the same tonight. 

My model projects Allen to throw for 225.48 yards and 1.6 touchdowns while adding 30.29 yards and 0.45 touchdowns with his legs. Despite being the highest-projected player on the slate, I prefer the likes of Shakir and Cook in the captain/MVP spot for salary reasons and the limited ceiling Allen provides due to my projected game script. 

Jauan Jennings - WR, $7,400 (DK), $10,500 (FD)

Key Stats

  • 2024 Stats: 65 targets, 47 receptions, 628 receiving yards, and four touchdowns.
  • Opponent DVOA vs. WR2: 15.3%

I’ll flip the field and look at my first San Francisco player of the night, Jauan Jennings. Jennings draws the strongest matchup in the 49ers offense. It’s anticipated that Purdy will be under center for the 49ers tonight, and Jennings continues to be a strong and reliable option for Purdy in the passing game. He’s caught 15 of his 18 targets in the last two games with Purdy. 

My model projects Jennings to catch 4.79 of his 6.92 targets for 55.59 yards and 0.37 touchdowns. 

Other Flex Options: Christian McCaffrey, Brock Purdy, Amari Cooper, George Kittle

 

Value Plays - NFL DFS Lineup Picks

Jake Moody - K, $5,200 (DK), $8,500 (FD)

Key Stats

  • 2024 Stats: 18/22 field goals made/attempted, 17/17 extra points made/attempted.

I’ll stick with the San Francisco side as we head into our value options. Jake Moody is a good start. I believe that the San Francisco offense can do enough to move the ball against this seventh-ranked Bills defense, at the very least.

However, the question remains what Kyle Shanahan’s offense will do on the Buffalo cold on the Bills’ side of the field? I’m projecting there will be multiple instances where the Niners will have to settle for a field goal, giving Moody a solid floor. 

Dawson Knox - TE, $4,000 (DK), $7,000 (FD)

Key Stats

  • 2024 Stats: 22 targets, 14 receptions, 182 receiving yards, one touchdown.
  • Opponent DVOA vs. TE: -10.3%

I’ll wrap things up with Dawson Knox. Knox will see most of the tight-end snaps in this one as Dalton Kincaid misses his second straight game with a knee injury. Knox did well in his escalated role last week, catching four of six targets for 40 yards against the Chiefs. 

Tonight, my model projects Knox to catch 3.96 of his 5.29 targets for 39.03 yards and 0.41 touchdowns. He is the best value option on the slate and will likely be the highest-owned. I do find this “chalk” to be worth it, and I won’t be missing out here. 

Other Value Options: Ty Johnson, Ricky Pearsall, Ray Davis, Bills D/ST

Enjoy the rest of your weekend, and good luck, everyone! 



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Weekly DFS Analysis




POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

RANKINGS

QB
RB
WR
TE
K
DEF

RANKINGS

QB
RB
WR
TE
K
DEF

REAL-TIME FANTASY NEWS

Santi Aldama

Sidelined Again on Friday
Shota Imanaga

Showing Increased Velocity With Better Health
Jalen Williams

to Be Re-Evaluated In Two Weeks
Carson Whisenhunt

Velocity Up This Spring
Shai Gilgeous-Alexander

to Miss At Least One More Week
Jusuf Nurkić

Jusuf Nurkic Won't Face Memphis on Friday Night
Lane Thomas

Says he's Fully Healthy
Keyonte George

Not Ready to Return on Friday
Sandro Mamukelashvili

Collin Murray-Boyles, Sandro Mamukelashvili Cleared To Play Thursday
Randy Vásquez

Randy Vasquez has "Inside Track" on Rotation Spot
Kutter Crawford

a Candidate to Start Season on Injured List
Noah Clowney

is Ready to Play on Thursday
Michael Porter Jr.

is Returning on Thursday
Jalen Smith

is Cleared for Thursday's Game
Aaron Nesmith

to Play on Thursday
Tre Jones

to Suit Up on Thursday
Coby Mayo

Might Have an Opening at Third Base
Josh Giddey

is Available for Thursday's Contest
OG Anunoby

is Cleared for Thursday's Game
Seranthony Domínguez

Seranthony Dominguez Named White Sox's Closer
T.J. McConnell

Out of Action Versus Wizards
Gavin Williams

Mechanical Adjustment Helped Gavin Williams Break Out in 2025
Stephen Curry

Sidelined Again on Thursday
Malik Monk

Set to Return on Thursday
Rhett Lowder

Looking "Very Polished" in Camp
Christian Encarnacion-Strand

Could Play in Games Next Week
Russell Westbrook

Set to Suit Up Thursday
Moisés Ballesteros

Moises Ballesteros Should be in Camp This Weekend
Matthew Boyd

Could Be a Candidate to Regress in 2026
Griffin Jax

Could Re-Emerge as a Dominant Reliever in Tampa Bay
Heliot Ramos

Can Heliot Ramos Maintain an Everyday Role in 2026?
Ezequiel Tovar

Primed for 2026 Bounce-Back?
Wander Franco

"Confident and Optimistic" Heading into Upcoming Trial
Lourdes Gurriel Jr.

Takes Live Batting Practice
Drew Rasmussen

to Start on Opening Day for Rays
Reynaldo López

Reynaldo Lopez Sitting at 93-94 MPH in Camp
Thomas White

Falling Out of Favor for Opening Day Rotation
Robby Snelling

Not Projected to Make Starting Rotation
Collin Murray-Boyles

on Track to Play Thursday
Jalen Smith

Will Likely Play Thursday Against Toronto
Tre Jones

Upgraded to Probable
Sandro Mamukelashvili

is Questionable in Chicago
Logan Cooley

Sheds Non-Contact Jersey
Maxwell Crozier

to Miss 10 Weeks After Surgery
Kirill Marchenko

Dealing With Lower-Body Injury
Petr Mrazek

Undergoes Season-Ending Surgery
Victor Hedman

Suffers Lower-Body Injury
Sidney Crosby

Considered Day-to-Day
Rashee Rice

Accused of Assault by Long-Time Girlfriend
Ben Griffin

Looking to Return to Top Form at Riviera
Keegan Bradley

Looking to Build Momentum at Riviera
J.J. Spaun

Putting a Major Concern at Riviera
Sepp Straka

May Have Tough Time at The Genesis Invitational
Shane Lowry

Trending Up Entering the Genesis Invitational
Justin Rose

Off Most Radars at The Genesis Invitational
Robert MacIntyre

a Long Hitter to Watch at Riviera Country Club
Jake Knapp

Red-Hot Heading to Riviera
Min Woo Lee

Attempts to Build Momentum After Pebble Beach
Harry Hall

an Unknown for The Genesis Invitational
Matt Fitzpatrick

Has Favorable Path to Success at Riviera This Week
Wyndham Clark

Not Likely to Contend at Genesis Invitational
Ludvig Aberg

Might Find the Genesis Invitational More Challenging
Harris English

Carries Strong Form to Riviera
Patrick Cantlay

Eyes Another Strong Week at The Genesis Invitational
Daniel Berger

Needs Short Game to Show Up at Riviera
Sam Burns

Hopes Return to Form Continues at Riviera
Collin Morikawa

Riding Wave of Victory Into Riviera
Hideki Matsuyama

Looks to Have Repeat Success at The Genesis Invitational
Scottie Scheffler

Looks to Find Paydirt at Riviera
Xander Schauffele

Rounding into Form Before Genesis Invitational
Morgan Rielly

Available After Olympic Break
Charlie Lindgren

Practices Fully Tuesday
John Carlson

Ready to Rock After Olympics
Radek Faksa

Unavailable Against Team Canada
Anton Lundell

Good to Go Wednesday
Brandon Bussi

Earns Three-Year Extension
SJ

Sharks Terminating Jeff Skinner's Contract
Mike Evans

Will Return in 2026
Kenneth Walker III

Seahawks Not Expected to Use Franchise Tag on Kenneth Walker III
Bucky Irving

Undergoes Offseason Shoulder Surgery
Tyreek Hill

Says he Will Play in 2026
Joey Logano

Finishes Third in the 2026 Daytona 500
Ricky Stenhouse Jr

. Finishes as the Runner-Up in the Daytona 500
Chase Elliott

Falls Short of His First Daytona 500 Victory Again
Brad Keselowski

Ends Daytona 500 With a Top-Five Finish
Tyler Reddick

Wins the Daytona 500 for the First Time with 23XI Racing
Tyreek Hill

Released by Dolphins
Joey Logano

Should DFS Players Roster Joey Logano At Daytona?
Ryan Blaney

Is Ryan Blaney Worth Rostering for DFS at Daytona?
Chase Briscoe

May Not be Worth DFS Consideration for Daytona
Chase Elliott

Is Chase Elliott Worth Rostering At Daytona This Week For DFS?
Austin Cindric

May Be Worth Rostering At Daytona
Cleveland Browns

Browns to Spend Top Draft Picks on Receiver or Offensive Lineman?
Brad Keselowski

Is Brad Keselowski Worth Rostering for Daytona Lineups?
Tyler Reddick

May be A Solid and Sneaky Pick for Daytona Lineups
Alex Bowman

is A Highly Favorable Mid-Tier Option for Daytona
Ross Chastain

Could be A Top DFS Scorer for Daytona
Justin Allgaier

is One of the Safest DFS Options for Daytona
Tim Stützle

Tim Stutzle Matches Team Germany Record With Third Goal
Jack Eichel

Off to Hot Start in Olympics
OTT

Mads Sogaard Injured Saturday
NASCAR

Christoper Bell Emerging As One of The Best at Daytona
William Byron

Trying for Third Straight Daytona 500 Victory
Kyle Larson

Has Never Posted a Top-Five Finish at Daytona
Denny Hamlin

Is Denny Hamlin Overrated at Daytona?
Chris Buescher

an Easy DFS Pick for the Daytona 500
Kyle Busch

on Pole, Still Searching for Elusive Daytona 500 Victory
Lucas Raymond

Ties Team Sweden Record With Three Points Saturday
Anton Lundell

Battling Illness
Kevin Fiala

Out for the Season