👉 TAP TO SAVE 30% WITH CODE NEW
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

MNF NFL DFS Lineup Picks for FanDuel, DraftKings - Rams vs 49ers Showdown

John's top NFL DFS lineup picks for FanDuel, and DraftKings for Monday Night Football - Rams vs 49ers showdown slate. His Week 10 MNF daily fantasy football advice.

Happy Monday, RotoBallers! I hope your Week 10 has been profitable so far. I personally had a great day in cash yesterday, cleaning the house on all four of the major slates. I hope to carry this momentum into tonight in what should be an exciting matchup as the Rams (7-2) try to bounce back from last week's performance as they head to San Francisco for another prime-time matchup against the 49ers (3-5). Thanks to the advanced analytics of today, I'll do my best to provide you with as much in-depth analysis as possible regarding positional matchups and the like to help put some lunch money in your pocket. Let's break it down. 

In this article I will be providing you with daily fantasy football picks on FanDuel and DraftKings for the Monday Night Football slate on November 15th. These lineups can vary from higher-priced players and elite options to lower-priced players and value picks on both DraftKings and FanDuel.

If you have any questions you can follow me on Twitter @LucidMediaDFS and fire away, or sign up for a premium RotoBaller NFL package and chat with me and other NFL DFS analysts any time you'd like. Let's make some coin this season gang, and let's get right to it!

Featured Promo: Looking for some more fantasy football action? Adopt a dynasty orphan team over at FFPC. Sign up today and get $25 off any FFPC league. Sign Up Now!

 

NFL DFS Captain Plays

Matthew Stafford ($16,200 DK, $17,000 FD)

Key Stats:

  • 2021 Stats: 2,771 passing yards, 23 touchdowns, six interceptions.
  • Offensive Pass DVOA: 44.8% (3rd)
  • Opposing Defense Pass DVOA: 19.1% (25th)

Luckily we get a slight discount on Stafford tonight, with Cooper Kupp being the highest-priced player on DraftKings. It's unfortunate that the Rams lost Robert Woods this week, but they made a solid addition in Odell Beckham Jr. I don't think OBJ makes a massive difference in this game tonight, but with the matchup being what it is I think it's tough to fade Stafford. He's an absolute must in optimal lineups on FD, and I'll have a decent percentage of him on DK.

Recommendation: Cash (DK/FD)

Best Correlations: Cooper Kupp, Van Jefferson, Deebo Samuel

 

George Kittle ($11,700 DK, $10,500 FD)

Key Stats:

  • 2021 Stats: 36 targets, 25 receptions, 328 yards, one touchdown.
  • 2021 Data: 92.42% target rate, 21.3% target rate, 6.25% red-zone target rate, 2 end-zone targets
  • Opposing DVOA vs TE: -21.4% (8th)
  • Individual Matchup (vs Ernest Jones): 12% target per route, 90% catch rate, 0.25 fantasy points per route.

It's been an injury-ridden year for Kittle, but boy did he come back last week with a vengeance. After he missed four consecutive weeks, he logged six receptions on eight targets for 101 yards and a touchdown against Arizona last Sunday. Out of all the Niners' pass-catchers, Kittle has the best matchup of the week. He's shown recent success against the Rams, catching 20 of 26 targets for 191 yards and two touchdowns in his last three games against them.

Recommendation: Cash (DK), GPP (FD)

Best Correlations: Jimmy Garoppolo, Matthew Stafford, Cooper Kupp

Other Captains: Cooper Kupp, Brandon Aiyuk

 

NFL DFS Flex Plays

Jimmy Garoppolo ($10,000 DK, $14,000 FD)

Key Stats:

  • 2021 Stats: 1,754 passing yards, eight touchdowns, five interceptions.
  • Offensive Pass DVOA: 26% (8th)
  • Opposing Defense Pass DVOA: -6.7% (5th)

This is more of a FanDuel play for me, as I really don't think Jimmy G will be optimal on DraftKings tonight. I feel like the 49ers' 26% pass DVOA is a bit misleading, considering the 49ers really try to establish and use the run to move down the field. The matchup isn't particularly great either, but it's worth noting that Garoppolo threw for 268 yards and three touchdowns against the Rams last October. Overall though, I'd rather spread my ownership around the 49ers pass catchers and use the extra salary elsewhere on DraftKings.

Recommendation: Cash (FD), GPP (DK)

Best Correlations: George Kittle, Deebo Samuel, Cooper Kupp

 

Elijah Mitchell ($6,400 DK, $11,500 FD)

Key Stats:

  • 2021 Stats: 89 attempts, 469 rushing yards, three rushing touchdowns, nine targets, nine receptions, 73 receiving yards.
  • 2021 Data: 64.82% snap rate, 57.42% attempt rate, 47.62% red-zone attempt rate, 25% attempt rate withing the 5yd line.
  • Offensive Rush DVOA: 3.5% (3rd)
  • Opposing Defense Pass DVOA: -13.5% (14th)
  • Opposing DVOA vs RB (receiving): -4.1% (18th)

I'm a bit confused as to why Mitchell is so cheap on DraftKings, but we'll take it nonetheless. He showed his versatility last week, catching five of five targets for 43 yards, but this week I would have to assume Kyle Shanahan's game plan will be to use Mitchell and the running game to control the clock and keep the ball out of Matthew Stafford's hands. We could get dumped if the game becomes too out of hand too quickly, but the upside is certainly worth the risk.

Recommendation: Cash (DK, FD), GPP (CPT, DK)

Best Correlations: Matthew Stafford, George Kittle, Robbie Gould

Other Flex Plays: Deebo Samuel, Tyler Higbee, O'dell Beckham Jr.,

 

NFL DFS Value Plays

Van Jefferson Jr. ($5,400 DK, $8,000 FD)

Key Stats:

  • 2021 Stats: 46 targets, 27 receptions, 433 yards, three touchdowns.
  • 2021 Data: 78.19% snap rate, 14.33% target rate, 11.94% red-zone target rate, five end-zone targets.
  • Defensive DVOA vs 'Other WR': 10.3% (25th)
  • Individual Matchup (vs Emmanuel Moseley): 19% target per route, 54% catch rate, 0.21 fantasy points per route.

I understand why Jefferson is a bit cheaper, as the news about Robert Woods's ACL injury didn't come out until Friday. Again, we'll take the value we can get on this slate, especially because I truly don't believe that OBJ will have a huge factor in this game. Robert Woods took up 21.5% of the target share, so it's not crazy to assume guys like Jefferson and Higbee will have some positive regression in the target department. While his matchup is average, it shouldn't be hard for Jefferson to hit value tonight, and he's a must-play in cash lineups on DK.

Recommendation: Cash (DK/FD)

Best Correlations: Matthew Stafford, Jimmy Garoppolo

 

Rams D/ST ($4,600 DK)

Key Stats:

  • 2021 Stats: 28 sacks, 12 interceptions, two fumble recoveries.
  • Defensive DVOA: -9.4% (9th)
  • Opposing Offense DVOA: 13.1% (7th)

I consider this more of a GPP play tonight, as I'm about 50/50 on which way this game could go. You really never know what you're going to get from San Francisco's offense, but I do think there's a very real chance that Jimmy is a dud tonight and the Rams absolutely dominate. They've been ball-hawking all season and should get some decent pressure on Garoppolo and force him to make mistakes. It's also worth that in the last two games against the Rams they've allowed 23 and 24 points.

Recommendation: GPP (DK)

Best Correlations: Darrell Henderson Jr., Matthew Stafford, Robbie Gould

Other Value Plays: Robbie Gould, Matt Gay

 

NFL DFS: Overall Slate Notes

I think this is a super interesting, yet unpredictable matchup. I think the Rams snap their four-game losing streak against San Francisco, but I also think that this should be a game that could go down the wire. All outcomes feel possible, so I'll be spreading my lineups out accordingly. Unlike last night, though, I do think this game can be a "cash" slate as well, as both offenses seem rather consolidated. I know it's somewhat "going against the grain" to play cash games in a showdown slate, but I've found myself having success over the last few years.

Have a good week everyone, good luck, and I'll talk to you again on Thursday. 



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Weekly DFS Analysis




POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

De'Von Achane

Not Present for Start of Voluntary Workouts
Malik Nabers

Present for Start of Offseason Program
NFL

Fernando Mendoza Not Planning to Attend the NFL Draft
New York Giants

Dexter Lawrence to Get a New Deal From Giants?
Carolina Panthers

Diego Pavia Visiting With Panthers on Tuesday
Pittsburgh Steelers

Steelers Hosting Denzel Boston on Pre-Draft Visit on Tuesday
Malik Willis

Dolphins Looking to Build Around Malik Willis
Kyle Pitts Sr.

Signs Franchise Tag, Present for Offseason Workouts
Tommy Fleetwood

a Contender if his Putter Cooperates at The Masters
Evan Engram

Fading Value Could Sink Even Lower After NFL Draft
TreVeyon Henderson

Experience and Emphasis on Run Game Could Help TreVeyon Henderson's Value Soar
Caleb Williams

The Sky is the Limit for Caleb Williams in Second Season with Ben Johnson
Nikita Kucherov

Nets 400th Career Goal
Elijah Arroyo

Are the Pieces in Place for a Year 2 Jump From Elijah Arroyo?
Evander Kane

Unlikely to Play Tuesday
Tre Tucker

Could Be an Early-Season Sell Candidate
Kevin Lankinen

Won't Dress on Tuesday
Morgan Barron

Considered Week-to-Week
Pontus Holmberg

Suffers Upper-Body Injury Monday
Philipp Grubauer

Exits With Injury Monday
Andrew Nembhard

Misses Fourth Consecutive Game
Pascal Siakam

Unavailable Tuesday Night
Matas Buzelis

Misses Second Straight Game Due to Illness
Josh Giddey

Out on Tuesday
Jalen Williams

Won't Play Against Lakers
Anthony Edwards

Remains on the Shelf Tuesday
Victor Wembanyama

Sustains Bruised Rib Versus 76ers
Jack Bech

Could be a Nice Buy-Low Candidate Going into Sophomore Season
Mark Scheifele

Collects Three Helpers on Monday
Jacob deGrom

Pitches Through Knee Issue on Monday
Ukko-Pekka Luukkonen

Defeats the Lightning
Dalton Rushing

Smacks Two Homers in Rout of Blue Jays
Jaydon Blue

Will Jaydon Blue Remain the Cowboys' RB2 After the Draft?
Max Scherzer

Dealing With Forearm Tendinitis, Expected to Make his Next Start
Oronde Gadsden

Due for a Year 2 Breakout?
Collin Morikawa

Vegas has Lost Confidence in Collin Morikawa Ahead of Masters Tournament
Keaton Mitchell

to Play a Key Role on New Team?
Ludvig Aberg

One of the Top Plays For This Week's Masters Tournament
Isaiah Bond

Is Isaiah Bond Due for a Year 2 Breakout or a Reduced Role?
James Cook

Continues to Trend Up Every Year
Rory McIlroy

Set to Defend his Long-Awaited Masters Victory
Bryson DeChambeau

Looks to Finally Claim a Green Jacket
Patrick Cantlay

Needs Plenty to Go Right at Augusta
Harris English

Playing Solid Golf Heading to Masters
Sam Burns

Bouncing Back Nicely After Slow Start to 2026 Season
Corey Conners

Quietly Putting Together A Strong 2026 Season
Russell Henley

Looks to Bounce Back At Masters
Robert MacIntyre

Hopes to Rebound After Missed Cut at Masters Last Year
Justin Rose

Ready to Put Heartbreaking Playoff Loss Behind Him
Matt Fitzpatrick

Heads to Masters After Winning Valspar Championship
Xander Schauffele

Continues Scorching Start to 2026 Season
Scottie Scheffler

Returns to Action For Masters
Maverick McNealy

Might Perform Well Early at Masters Tournament
Gary Woodland

Riding the Wave Heading into Augusta National
Greg Dulcich

Will Have an Opportunity for a Big Role in 2026
Jacksonville Jaguars

Jaguars Love Their Running Back Room
Rasmus Hojgaard

Seeks to Continue Momentum from Houston
Shane Lowry

Attempting to Turn Back Time at the Masters
Sepp Straka

Trying to Get Under Par At Augusta
Viktor Hovland

Seeks a Hot Start at the Masters Tournament
Dean Wade

Jaylon Tyson and Dean Wade Set to Sit Out Again on Monday
Thomas Bryant

Unavailable on Monday
Andrew Mangiapane

Available for Monday's Tilt
Max Strus

Ruled Out Against Grizzlies
Shane Wright

Expected to Miss Another Game
Jarrett Allen

Available on Monday
Vladislav Namestnikov

Available Monday
Anthony Cirelli

Out Against Sabres
Evan Mobley

Active Against Memphis
Nino Niederreiter

Rejoins Jets Lineup
Brandon Hagel

Sits Out Third Consecutive Game
DAL

Nathan Bastian to Miss 3-4 Weeks
Mike Trout

Held Out of Series Opener Against Braves
Sam Merrill

Set to Suit Up on Monday
Donovan Mitchell

Ruled Out Monday
Alejandro Kirk

to Undergo Thumb Surgery on Tuesday
James Harden

Out Monday
Juan Soto

Mets Place Juan Soto on 10-Day Injured List
Matthew Boyd

Cubs Putting Matthew Boyd on 15-Day Injured List With Biceps Strain
Mickey Moniak

Goes Yard Twice Against his Old Team
Brent Rooker

Homers Twice, Drives in Six in Win Over Astros
Mike Trout

Considered Day-to-Day With Hand Contusion
Vít Krejčí

Vit Krejci Still Sidelined Monday
Bruce Brown

Likely Available vs. Portland
Spencer Jones

Remains Sidelined Monday
Isaiah Stewart

Remains Out Monday vs. Orlando
Dillon Brooks

Risks Suspension After 18th Technical Foul
Daniel Gafford

Leaves Game Early with Shoulder Injury
Will Cuylle

Grabs First Career Hat Trick in Blowout Win
Jacob Markstrom

Records First Shutout of the Season
Brady Tkachuk

Scores Twice Against Hurricanes
Sidney Crosby

Registers Three Points in Sunday's Win
Robert Thomas

Pots First Career Hat Trick
Valeri Nichushkin

Labeled Day-to-Day
Chris Duncan

Suffers Second-Round Submission Loss
Renato Moicano

Gets Back In The Win Column
Tabatha Ricci

Gets Outgrappled
Virna Jandiroba

Bounces Back
Brendson Ribeiro

Suffers First-Round Submission Loss
Abdul-Rakhman Yakhyaev

Earns First-Round Submission Win
Rafael Estevam

Suffers His First Loss
Ethyn Ewing

Dominates At UFC Vegas 115
Mike Trout

Exits Early After Getting Hit by Pitch
Pete Fairbanks

Serving as Opener Before Going on Paternity List
George Klassen

Called Up to Start on Sunday
Hunter Brown

Placed on 15-Day Injured List with Right-Shoulder Strain
Jesús Luzardo

Jesus Luzardo Dominates Rockies on Saturday
Byron Buxton

Back in Sunday's Lineup
Mookie Betts

Heading to the Injured List With Oblique Strain
Cade Horton

Cubs Place Cade Horton on 15-Day Injured List With Forearm Strain
Mookie Betts

Considered Day-to-Day, Heading for an MRI on Saturday
Juan Soto

Day-to-Day With Minor Groin Strain, No Decision on IL Yet
MLB

Cubs-Guardians Game Postponed on Saturday
Chris Duncan

Set For UFC Vegas 115 Main Event
Renato Moicano

An Underdog At UFC Vegas 115
Tabatha Ricci

Set For UFC Vegas 115 Co-Main Event
Virna Jandiroba

Looks To Bounce Back
Brendson Ribeiro

In Desperate Need Of Win
Abdul-Rakhman Yakhyaev

Looks To Remain Unbeaten
Ethyn Ewing

Set For His Second UFC Bout
Rafael Estevam

Looks To Remain Undefeated
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF