👉 TAP TO SAVE 50% WITH CODE SPRING
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Draft Rankings
Draft Simulator
Compare Any Players
24x7 News and Alerts

MNF NFL DFS Lineup Picks for FanDuel, DraftKings - Rams vs 49ers Showdown

John's top NFL DFS lineup picks for FanDuel, and DraftKings for Monday Night Football - Rams vs 49ers showdown slate. His Week 10 MNF daily fantasy football advice.

Happy Monday, RotoBallers! I hope your Week 10 has been profitable so far. I personally had a great day in cash yesterday, cleaning the house on all four of the major slates. I hope to carry this momentum into tonight in what should be an exciting matchup as the Rams (7-2) try to bounce back from last week's performance as they head to San Francisco for another prime-time matchup against the 49ers (3-5). Thanks to the advanced analytics of today, I'll do my best to provide you with as much in-depth analysis as possible regarding positional matchups and the like to help put some lunch money in your pocket. Let's break it down. 

In this article I will be providing you with daily fantasy football picks on FanDuel and DraftKings for the Monday Night Football slate on November 15th. These lineups can vary from higher-priced players and elite options to lower-priced players and value picks on both DraftKings and FanDuel.

If you have any questions you can follow me on Twitter @LucidMediaDFS and fire away, or sign up for a premium RotoBaller NFL package and chat with me and other NFL DFS analysts any time you'd like. Let's make some coin this season gang, and let's get right to it!

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

NFL DFS Captain Plays

Matthew Stafford ($16,200 DK, $17,000 FD)

Key Stats:

  • 2021 Stats: 2,771 passing yards, 23 touchdowns, six interceptions.
  • Offensive Pass DVOA: 44.8% (3rd)
  • Opposing Defense Pass DVOA: 19.1% (25th)

Luckily we get a slight discount on Stafford tonight, with Cooper Kupp being the highest-priced player on DraftKings. It's unfortunate that the Rams lost Robert Woods this week, but they made a solid addition in Odell Beckham Jr. I don't think OBJ makes a massive difference in this game tonight, but with the matchup being what it is I think it's tough to fade Stafford. He's an absolute must in optimal lineups on FD, and I'll have a decent percentage of him on DK.

Recommendation: Cash (DK/FD)

Best Correlations: Cooper Kupp, Van Jefferson, Deebo Samuel

 

George Kittle ($11,700 DK, $10,500 FD)

Key Stats:

  • 2021 Stats: 36 targets, 25 receptions, 328 yards, one touchdown.
  • 2021 Data: 92.42% target rate, 21.3% target rate, 6.25% red-zone target rate, 2 end-zone targets
  • Opposing DVOA vs TE: -21.4% (8th)
  • Individual Matchup (vs Ernest Jones): 12% target per route, 90% catch rate, 0.25 fantasy points per route.

It's been an injury-ridden year for Kittle, but boy did he come back last week with a vengeance. After he missed four consecutive weeks, he logged six receptions on eight targets for 101 yards and a touchdown against Arizona last Sunday. Out of all the Niners' pass-catchers, Kittle has the best matchup of the week. He's shown recent success against the Rams, catching 20 of 26 targets for 191 yards and two touchdowns in his last three games against them.

Recommendation: Cash (DK), GPP (FD)

Best Correlations: Jimmy Garoppolo, Matthew Stafford, Cooper Kupp

Other Captains: Cooper Kupp, Brandon Aiyuk

 

NFL DFS Flex Plays

Jimmy Garoppolo ($10,000 DK, $14,000 FD)

Key Stats:

  • 2021 Stats: 1,754 passing yards, eight touchdowns, five interceptions.
  • Offensive Pass DVOA: 26% (8th)
  • Opposing Defense Pass DVOA: -6.7% (5th)

This is more of a FanDuel play for me, as I really don't think Jimmy G will be optimal on DraftKings tonight. I feel like the 49ers' 26% pass DVOA is a bit misleading, considering the 49ers really try to establish and use the run to move down the field. The matchup isn't particularly great either, but it's worth noting that Garoppolo threw for 268 yards and three touchdowns against the Rams last October. Overall though, I'd rather spread my ownership around the 49ers pass catchers and use the extra salary elsewhere on DraftKings.

Recommendation: Cash (FD), GPP (DK)

Best Correlations: George Kittle, Deebo Samuel, Cooper Kupp

 

Elijah Mitchell ($6,400 DK, $11,500 FD)

Key Stats:

  • 2021 Stats: 89 attempts, 469 rushing yards, three rushing touchdowns, nine targets, nine receptions, 73 receiving yards.
  • 2021 Data: 64.82% snap rate, 57.42% attempt rate, 47.62% red-zone attempt rate, 25% attempt rate withing the 5yd line.
  • Offensive Rush DVOA: 3.5% (3rd)
  • Opposing Defense Pass DVOA: -13.5% (14th)
  • Opposing DVOA vs RB (receiving): -4.1% (18th)

I'm a bit confused as to why Mitchell is so cheap on DraftKings, but we'll take it nonetheless. He showed his versatility last week, catching five of five targets for 43 yards, but this week I would have to assume Kyle Shanahan's game plan will be to use Mitchell and the running game to control the clock and keep the ball out of Matthew Stafford's hands. We could get dumped if the game becomes too out of hand too quickly, but the upside is certainly worth the risk.

Recommendation: Cash (DK, FD), GPP (CPT, DK)

Best Correlations: Matthew Stafford, George Kittle, Robbie Gould

Other Flex Plays: Deebo Samuel, Tyler Higbee, O'dell Beckham Jr.,

 

NFL DFS Value Plays

Van Jefferson Jr. ($5,400 DK, $8,000 FD)

Key Stats:

  • 2021 Stats: 46 targets, 27 receptions, 433 yards, three touchdowns.
  • 2021 Data: 78.19% snap rate, 14.33% target rate, 11.94% red-zone target rate, five end-zone targets.
  • Defensive DVOA vs 'Other WR': 10.3% (25th)
  • Individual Matchup (vs Emmanuel Moseley): 19% target per route, 54% catch rate, 0.21 fantasy points per route.

I understand why Jefferson is a bit cheaper, as the news about Robert Woods's ACL injury didn't come out until Friday. Again, we'll take the value we can get on this slate, especially because I truly don't believe that OBJ will have a huge factor in this game. Robert Woods took up 21.5% of the target share, so it's not crazy to assume guys like Jefferson and Higbee will have some positive regression in the target department. While his matchup is average, it shouldn't be hard for Jefferson to hit value tonight, and he's a must-play in cash lineups on DK.

Recommendation: Cash (DK/FD)

Best Correlations: Matthew Stafford, Jimmy Garoppolo

 

Rams D/ST ($4,600 DK)

Key Stats:

  • 2021 Stats: 28 sacks, 12 interceptions, two fumble recoveries.
  • Defensive DVOA: -9.4% (9th)
  • Opposing Offense DVOA: 13.1% (7th)

I consider this more of a GPP play tonight, as I'm about 50/50 on which way this game could go. You really never know what you're going to get from San Francisco's offense, but I do think there's a very real chance that Jimmy is a dud tonight and the Rams absolutely dominate. They've been ball-hawking all season and should get some decent pressure on Garoppolo and force him to make mistakes. It's also worth that in the last two games against the Rams they've allowed 23 and 24 points.

Recommendation: GPP (DK)

Best Correlations: Darrell Henderson Jr., Matthew Stafford, Robbie Gould

Other Value Plays: Robbie Gould, Matt Gay

 

NFL DFS: Overall Slate Notes

I think this is a super interesting, yet unpredictable matchup. I think the Rams snap their four-game losing streak against San Francisco, but I also think that this should be a game that could go down the wire. All outcomes feel possible, so I'll be spreading my lineups out accordingly. Unlike last night, though, I do think this game can be a "cash" slate as well, as both offenses seem rather consolidated. I know it's somewhat "going against the grain" to play cash games in a showdown slate, but I've found myself having success over the last few years.

Have a good week everyone, good luck, and I'll talk to you again on Thursday. 



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Weekly DFS Analysis




POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Draft Rankings
Draft Simulator
Compare Any Players
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Tyler Seguin

Expects to Be Ready for Training Camp
Sam Carrick

Could Practice Tuesday
Alexander Nikishin

Won't Play Monday
Jeremy Lauzon

Expected to Miss Round 2
William Karlsson

Rejoins Golden Knights Lineup Monday
Jackson Chourio

Brewers Reinstate Jackson Chourio From the Injured List
Malachi Fields

Could be "Power Forward" at Wide Receiver
Fernando Mendoza

Working on Playing Under Center
Cleveland Browns

Browns Not Naming a Leader in the QB Battle
Anthony Richardson Sr.

Reports for Voluntary Offseason Workouts
Aaron Rodgers

Steelers Losing Patience With Aaron Rodgers?
Skylar Thompson

Ravens Expected to Sign Skylar Thompson
DJ Giddens

Can DJ Giddens Re-Establish His Dynasty Value After Underwhelming Rookie Season?
Desmond Ridder

Packers Sign Tyrod Taylor, Release Desmond Ridder
AJ Barner

a Prime Regression Candidate Entering 2026
Tarik Skubal

to Undergo Elbow Surgery
Cedric Tillman

Losing Dynasty Value in Cleveland Following NFL Draft
Josh Jacobs

Should Dynasty Managers Consider Selling High on Josh Jacobs?
Xavier Legette

Dynasty Stock at an All-Time Low Entering 2026
Chase Elliott

Earns his Second Texas Motor Speedway Victory
Denny Hamlin

Misses Out on Winning at Texas
Alex Bowman

Finishes Third for the Second Week in a Row at Texas
Tyler Reddick

Earns Seventh Top-Five Finish of the Season at Texas
Chris Buescher

Scores his First Career Texas Finish in the Top Five
Rashod Bateman

Droppable in Many Dynasty Leagues
Mark Andrews

Should Dynasty Managers Hold Mark Andrews Until Midseason?
Tyrone Tracy Jr.

Can Maintain Fantasy Relevance When Teammate Returns
Chimere Dike

Trending Down Despite Solid Rookie Season?
Jameson Williams

Needs to Show More Consistency in Clearly Defined Role
CFB

Bryce Underwood in Better Situation Entering Sophomore Season
CFB

Nico Iamaleava Emerging as Leader, Playmaker for UCLA
Raisel Iglesias

to be Activated on Tuesday
Orlando Magic

Jamahl Mosley Out as Magic Head Coach
Chase Brown

Stock Back on the Rise After Surviving Another Offseason
Scottie Barnes

Caps Season with Efficient Game 7 Showing
Donovan Mitchell

Finishes with 22 Points in Deciding Game
J.K. Dobbins

a Depreciating Dynasty Asset
Jarrett Allen

Leads Frontcourt Effort with 19 Rebounds
C.J. Stroud

Can C.J. Stroud End His Dynasty Slide?
Paolo Banchero

Carries Offense in Game 7 Defeat
Jalen Duren

Posts 15-15 Line in Game 7 Win
Parker Washington

Still Undervalued Despite Proven Upside
Tobias Harris

Stays Hot with 30 Points in Win
Cade Cunningham

Shines as Pistons Advance to Semifinals
Jack Della Maddalena

Gets Dominated At UFC Perth
Carlos Prates

Shines At UFC Perth
Jakub Dobes

Backstops Canadiens to Game 7 Victory
Beneil Dariush

Suffers A First-Round TKO Loss
Quillan Salkilld

Remains Unbeaten In The UFC
Quinn Hughes

Takes Over Postseason Scoring Lead With Three-Point Effort
Cale Makar

Shakes Off Injury to Collect Three Points in Game 1
Owen Tippett

a Game-Time Decision Monday
Logan Stanley

Practices Fully Sunday
Sam Carrick

Will Miss Second-Round Matchup
Tim Elliott

Drops Decision At UFC Perth
Noah Ostlund

Expected to Miss Round 2
Steve Erceg

Wins Back-To-Back Fights
Ollie Schmid

Suffers First-Round TKO Loss
Marwan Rahiki

Remains Unbeaten
Bryce Eldridge

Giants to Promote No. 1-Ranked Prospect Bryce Eldridge to MLB Roster
Jonas Brodin

Out for Games 1 and 2 Against Colorado
Joel Eriksson Ek

Will Miss First Two Games of Colorado Series
Joel Kiviranta

Remains Out of the Lineup Versus Minnesota
Anthony Volpe

Reinstated From Injured List, Optioned to Triple-A
Josh Manson

Out for Game 1 Against Minnesota
Carter Bryant

Iffy for Game 1 Against Timberwolves
Joel Embiid

Considered Probable for Monday
Kyle Anderson

Available for Round 2 Opener
Ayo Dosunmu

Tagged as Questionable on Injury Report
Anthony Edwards

Listed as Questionable for Game 1 Against Spurs
Luka Dončić

Luka Doncic Unavailable for Start of Round 2, Considered Week-to-Week
Brandon Ingram

Won't Play in Game 7 Against Cavaliers
Ranger Suarez

Exits Sunday's Start With Hamstring Tightness
Agustín Ramírez

Marlins Demote Agustin Ramirez to Triple-A
Victor Hedman

Will Not Play Sunday Versus Montreal
Noah Dobson

Will Play Against Tampa Bay on Sunday
Ben Rice

Exits Sunday's Contest With Left-Hand Contusion
Kevin Huerter

is Out for Game 7
Nikola Vučević

Nikola Vucevic Could be Done in Boston
Christopher Bell

Is Christopher Bell Worth Rostering for Texas Lineups?
Cal Raleigh

Considered Day-to-Day With Soreness in his Side
Brandon Ingram

is Downgraded to Doubtful for Game 7
William Byron

Might have the Speed to Compete for the Win at Texas
Jonathan Isaac

Remains Out for Game 7
Joey Logano

Provides Solid Upside for Texas DFS Lineups
Joe Ryan

Exits Early From Start on Sunday Due to Elbow Soreness
Chase Briscoe

Could Chase Briscoe be A Sneaky Pick for Texas Lineups?
Ty Gibbs

Should DFS Managers Roster Ty Gibbs at Texas?
Daniel Suarez

Is Daniel Suarez Worth Rostering After Career-Best Starting Position at Texas?
Daniel Palencia

Cubs Reinstate Daniel Palencia From the Injured List on Sunday
Kyle Busch

Is a DFS Risk Starting in the Top 10 at Texas
Ronald Acuña Jr.

Braves Place Ronald Acuna Jr. on Injured List With Strained Hamstring
Nick Lodolo

Expected to Make Season Debut on Friday
Tyler Reddick

One of the Favorites to Win at Texas
Chase Elliott

Could Contend for Another Win at Texas
Carson Hocevar

on Pole at Texas
NASCAR

Bubba Wallace Wrecks in Practice at Texas
Chris Buescher

Looking to Continue Strong Run at Texas
Austin Dillon

Blows Engine in Practice at Texas
Derrick White

Delivers All-Around Line in Game 7 Loss
Neemias Queta

Finishes with Double-Double in Playoff Loss
Mike Reilly

Delivers Two Assists in Game 1 Win
Logan Stankoven

Establishes New Franchise Record With Five-Game Goal Streak
Frederik Andersen

Records Second Postseason Shutout
Cal Raleigh

Scratched From Lineup, No Reason Given
Ronald Acuña Jr.

Ronald Acuna Jr. Exits With Left-Hamstring Tightness
Yandy Díaz

Yandy Diaz Leaves With Side Tightness, Considered Day-to-Day
Jacob Misiorowski

Leaves Start Early on Friday With Hamstring Cramp
Brandon Nimmo

Aggravates Hamstring, Pulled Early on Friday
Ryan Helsley

Placed on Injured List With Elbow Inflammation
Ryan Pepiot

to Miss the Rest of the Season, Scheduled for Hip Surgery
Brandon Woodruff

Goes on Injured List With Shoulder Inflammation
Jack Della Maddalena

Returns At UFC Perth
Carlos Prates

Set For UFC Perth Main Event
Quillan Salkilld

Set For Co-Main Event
Beneil Dariush

An Underdog At UFC Perth
Steve Erceg

Looks To Win Back-To-Back Fights
Tim Elliott

Looks For His Third Consecutive Win
Ollie Schmid

Set For His UFC Debut
Marwan Rahiki

Looks To Remain Undefeated
Gary Woodland

Riding Momentum Into Cadillac Championship
Jordan Spieth

Brings Boom-or-Bust Potential to Cadillac Championship
Adam Scott

Looks Poised for Another Strong Finish at Doral
Maverick McNealy

Needs Approach Game to Click at Doral
CFB

Jameson Williams Files Lawsuit Against NCAA, SEC, Big Ten
Harry Hall

Volatility Continues at Cadillac Championship
Tommy Fleetwood

Looks to Rebound at Trump National Doral
Pierceson Coody

a Risky Value Play at Cadillac Championship
Akshay Bhatia

Offers Upside with Risk at Cadillac Championship
Justin Thomas

a Scary Proposition at Cadillac Championship
Scottie Scheffler

The Leading Favorite at Cadillac Championship
Collin Morikawa

Still a Smash Play at Cadillac Championship
Viktor Hovland

Showed at Augusta He Can Finish Well
Sepp Straka

Attempting to Finish Better in Miami
PGA

J.J Spaun Enduring Roller Coaster Start to 2026
Min Woo Lee

Seeks to Make Adjustments at Cadillac Championship
Max Homa

May Struggle at Old Doral This Weekend
Ben Griffin

Rebounds From Rough Stretch as Miami Looms
Shane Lowry

Searching For Answers at Cadillac Championship
Russell Henley

Daunting Test at Doral Likely Not a Place For Russell Henley
Justin Rose

Returns to Action After Finishing Third at Masters Tournament
Hideki Matsuyama

Has The Approach Game to Win at Cadillac Championship
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF