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Is Joe Mixon out for the season? When is Joe Mixon coming back? The latest Joe Mixon injury update and fantasy football outlook heading into Week 10 of 2025.
Houston Texans starting running back Joe Mixon (foot) has yet to take the field this season and has remained on the non-football injury/reserve list since the beginning of the summer.
With Week 9 in the books, Mixon has not made any significant progress and is facing an uphill battle to return this season.
Will Mixon play again this season? Should fantasy managers stash him on their bench? Let's dive in!
Be sure to check all of our fantasy football rankings for 2025:- 2025 fantasy football rankings
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- Dynasty fantasy football rankings
Is Joe Mixon Out for the 2025 Season?
While the Texans have not officially ruled out Mxion for the remainder of the season, he is facing a lengthy process to return to action. Since hitting the non-football injury list back in August, the team has not provided any substantial update on his status.
Earlier in October, the team's general manager, Nick Caserio, said that Mixon's status remains "in limbo" and that they did not have a definitive timeline on his availability.
Given that the Texans have yet to provide a clear timeline for when he may return to practice, fantasy managers should not expect him to return this season. While it is still possible he could return, the potential for this outcome is fading rapidly.
No Timetable for Joe Mixon's Return https://t.co/Hib7RlCrYy
— RotoBaller NFL (@RotoBallerNFL) October 20, 2025
Joe Mixon 2025 Fantasy Football Outlook
Given the team's lack of updates, owners should not expect Mixon to carry any more fantasy value this season. As a result, managers in any 12-team format should not consider stashing him, even in an IR spot. While managers in deeper 14+ team formats with multiple IR spots could still consider stashing Mixon, his potential to return this season is very low, and it may be more beneficial to stash other IR candidates.
With Jayden Daniels (elbow) and Brian Thomas Jr. (ankle) potentially suffering severe injury on Sunday, managers will likely need to open an IR spot and will need to cut Mixon to stash these players instead.
Managers in shallower leagues should opt to pivot off Mixon in favor of high-upside handcuff running backs. For example, Los Angeles Rams running back Blake Corum, New York Jets backup running back Isaiah Davis, and Atlanta Falcons No. 2 option Tyler Allgeier are all prime stash options to hold instead of Mixon.
All three running backs could have high-end RB2 upside if their starter were to miss time. In addition, Davis could even become the starter on his club if the Jets were to move Breece Hall ahead of this week's NFL Trade Deadline.
Isaiah Davis Flashing Upside Amid Jets Trade Rumors https://t.co/0WzmrWNalw
— RotoBaller NFL (@RotoBallerNFL) October 30, 2025
When looking at high-upside WRs to target, managers should look to stars Christian Watson of the Green Bay Packers and Parker Washington of the Jacksonville Jaguars. With Tucker Kraft (knee) out for the season and Travis Hunter (knee) potentially sidelined for the remainder of the campaign, Watson and Washington could have a key role on their respective team during the entire second half.
Who Should I Start Tool
Not sure who to start? Check out the Who Should I Start tool:
Compare up to four players and we'll tell you who to start...
Who Should I Start? Who Should I Sit? Some common Week 10 fantasy football lineup decisions are regarding players like Troy Franklin, Zach Charbonnet, Romeo Doubs, Chimere Dike, Jordan Addison. But not to worry, we are here to help make these decisions and build winning lineups in Week 10. Set your optimal fantasy football lineups for Week 10 of the 2025 NFL season. Our free Who Should I Start? tool will help make your fantasy football lineup decisions. Compare up to four NFL players, and we tell you who to start... all free! Get your winning lineups set, and make the right decisions.
Week 10 Player Decisions. Today's focus is on specific players - Troy Franklin, Zach Charbonnet, Romeo Doubs, Chimere Dike, Jordan Addison. These are some of the most common searches for fantasy football lineups in Week 10.
Using The Tool. This is a simple tool, but very powerful. The first step is to enter the player names that you want to compare. In the first box, search for the first player's name. In the second box, search for the second player's name. Compare up to four NFL players at once, and then click the Who To Start? button to see who the recommended starts are based on weekly fantasy football matchups.
Improvements For Who Should I Start? You may have noticed that our 'Who Should I Start?' tool has gotten an overhaul. We've added lots of great features for you to give you as much information as possible to win your fantasy football matchups each week. You'll see NFL player tiles with headshots and bye weeks, stats, projections, strength of schedule, player news, and enhanced search results with data to compare with a slick new interface. We hope you enjoy!
How It Works. Each week, our RotoBaller staff puts together their weekly fantasy football rankings and projections based on their research. That information is the core data that is powering the decision-making in this tool. When you search for player names, you will only see those players who are ranked. If someone is out for the week, they will not appear in the search results.
Scoring Formats. Fantasy football managers play in various types of leagues, and this tool allows you to choose whether it's PPR scoring, Half-PPR scoring, or Standard (Non-PPR) scoring. The second thing you want to do is to select the scoring format. There are three small radio buttons (small circles), so click on the scoring format you prefer. The results may vary based on the scoring format you select.
Popular Week 10 Searches. Curious to see some tough lineup decisions for Week 10 (2025)? Below you will find a list of some popular Who Should I Start? searches that RotoBaller readers are looking at this week. Click any of the links to see the result and recommendation.
Popular Week 10 Searches - Start/Sit Player Comparisons
Below are some popular Week 10 searches and comparisons from our 'Who To Start' tool for Troy Franklin, Zach Charbonnet, Romeo Doubs, Chimere Dike, Jordan Addison compared to others:
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