🖥 CYBER WEEK - TAP TO SAVE 50% WITH CODE CYBER
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Daily Stats & Leaders
All Pitcher Matchups
Compare Any Players
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

Free MLB Betting Picks - Today's Best Bets, Expert Predictions, Odds (9/21/22)

Miles Mikolas - Fantasy Baseball Rankings, Draft Sleepers, MLB Injury News

John Brubaker's top MLB betting picks and best bets for today's MLB games on 9/21/22. His free picks against the spread, teasers, parlays, and MLB player props.

Happy Wednesday, RotoBallers, we're back for another week of MLB betting picks! Make sure you're following my Twitter, as I can't guarantee that I'll always be able to get the added plays written here in the article, but I will typically add whatever else I'm playing throughout the day. The entire RotoBaller team has been working around the clock to make sure we can get you guys the best betting picks, props, and lineups throughout the season. We're happy you're here with us and are looking forward to an extremely profitable 2022 season!

Attention fellow sports bettors! We have some exciting news to share as we are now officially partnered with various sportsbooks and have some sweet sports betting promo offers! Get your deposit bonus, as well as a year of free RotoBaller Premium access, when you sign up with a new account today! After you're signed up, use our picks in this article for spreads, totals, and props to win big.

If you're new, or just a refresher to those who read my articles last season, I'm John Brubaker. I've been betting MLB baseball games for four years now, and this is my second MLB season working with the great folks at RotoBaller. I've created my own betting model to help me create and identify value on run lines, totals, and money lines. In this article, I'll be providing my favorite betting picks for the MLB games on Wednesday, September 21, 2022.

Featured Promo: Get any Props Premium Pass for 50% off using code CYBER. Win more with our two new Props Optimizer tools -- one for PrizePicks Props, and one for Sportsbook Betting Props. Find optimal prop bets and get our recommended picks daily! Go Premium, Win More!

 

LucidMedia's 2022 MLB Betting Picks

  • Season to Date: 74-72-2, -15.43 units
  • Sides: 34-35-1, -12.72 units
  • Totals: 37-36-1, -4.41 units
  • Props: 1-0 +1.70 units

 

Today's MLB Betting Picks - Pirates @ Yankees

O/U: 8 | Moneyline: NYY -310

PIT: Roansy Contreras | NYY: Luis Severino

We finished 1-1 yesterday, as Kenley Jansen just couldn't stay out of trouble, allowing a run and effectively killing the Braves run line. That game ended up being a strange one and I'm sending positive vibes to Patrick Corbin, who left the game in the first inning.

We'll start the day off today with a first-inning under play in New York. The visiting Pirates will be sending Roansy Contreras (5-4, 3.24 ERA) to the mound. Contreras has been one of my favorites this year, considering he's been nothing short of perfect in the first inning this season. He's gone through each of his 15 starts, seven of which were on the road, without allowing a first-inning tally this season.

The Yankees will be sending Luis Severino (5-3, 3.45 ERA) to the mound. Severino has been solid both overall and the first inning this season, allowing a run in just two of nine starts in Yankee Stadium, and in just three of 13 starts overall. He should have no issue getting through a Pirates lineup that's been held scoreless in the opening frame in 82.3% of games overall, 84.2% on the road, and in eight of their last 10.

While FanDuel Sportsbook has the first inning under at -120, my model gives the under implied odds of 65.18%, good for "true" odds of -187. There's always the threat of an Aaron Judge home run in the bottom of the first, but I'll back Contreras to stay perfect under the bright lights of Yankee Stadium tonight.

Pick: Under 0.5 First Inning Runs (-120) FanDuel Sportsbook, 1 unit

 

Sports Betting Promo Offers

Featured Promo: Get any Betting Premium Pass for 50% off using code CYBER. Win more with exclusive betting picks from proven winners across 9 sports! Find optimal bets with our Betting Picks Tool and Bet Weighting Tool and follow along in our VIP chat rooms! Go Premium, Win More!

 

Today's MLB Betting Picks - Cardinals @ Padres

O/U: 7.5 | Moneyline: SD -123

STL: Miles Mikolas | SD: Blake Snell

We'll head out West to San Diego for another first inning under. We'll back Cardinals right-hander Miles Mikolas (11-12, 3.46 ERA). It's kind of shocking that Mikolas has accrued so many losses this season, given how well he's pitching and how well the Cardinals have played. Nevertheless, he's allowed a first-inning run in just two of 16 starts on the road as well as six of 30 starts overall. 

He'll match up with San Diego southpaw Blake Snell (7-9, 3.85 ERA). Snell has had a pretty solid bounce-back season for the Padres this year and has been excellent in the first inning. First-inning tallies have been few and far between with Snell on the mound, as he's allowed one in just two of 12 starts at Petco Park and in just three of 21 starts overall.

Despite both of these offenses (likely) leading their respective clubs to the playoffs, they haven't jumped on opposing pitchers in the first inning too often. The Cardinals have scored in roughly 32.4% of first innings overall, but that number drops to just 25.7% when on the road. The Padres on the other hand have scored in 24% of first innings overall and in 26.1% of first innings at home. The Cardinals have been held scoreless in nine of their last 10 while the Padres have been held scoreless in eight of their last 10.

FanDuel Sportsbook has the first inning under at -138, which is a surprising number given the low game total of 7.5. We'll take this value though, considering my model gives the under a 63.73% chance of hitting, good for "true" odds of -176. Let's avenge the unfortunate Braves loss last evening and go 2-0 today.

Pick: Under 0.5 First Inning Runs (-138) FanDuel Sportsbook, 1 unit

Good luck, RotoBallers, and make sure to follow my Twitter for more plays. Talk to you tomorrow!



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy baseball app for iPhone and Android with 24x7 player news, injury alerts, sleepers, prospects & more. All free!



More Fantasy Baseball Analysis




POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Daily Stats & Leaders
All Pitcher Matchups
Compare Any Players
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

REAL-TIME FANTASY NEWS

A.J. Brown

Continues Dominant Stretch With 100 Yards in Monday Night Loss
Saquon Barkley

Rips Off Long Touchdown Run in Monday Night Loss
Shohei Ohtani

to be Used More as Traditional Starting Pitcher Next Year
Yordan Alvarez

to Become Full-Time DH in 2026?
Mason Miller

Padres Plan to Keep Mason Miller in the Bullpen
Ranger Suárez

Orioles Interested in Signing Ranger Suarez
Anthony Volpe

Yankees Don't Expect Anthony Volpe to be Ready in April
Gerrit Cole

Targeting a Return in May/June
Riley Leonard

"Week-to-Week" With Strained Knee
NFL

Patriots-Ravens Week 16 Game Flexed to Sunday Night Football
Omarion Hampton

Making his Return on Monday Night
CFB

Heisman Trophy Finalists Announced on Monday
Justin Herbert

Officially Active Against Eagles
Indianapolis Colts

Colts Bringing Philip Rivers in for a Workout
Justin Herbert

Expected to Start on Monday Night
Trey Benson

Cardinals Could Hold Trey Benson Out Another Week
Keegan Murray

Available on Monday
Anthony Edwards

Set to Suit Up Monday
Jack Roslovic

Not Close to Returning
Dennis Schröder

Dennis Schroder Sidelined Again on Monday
Jake Walman

to Miss at Least Two More Weeks
Berkly Catton

Out Week-to-Week
Franz Wagner

Likely to Miss 2-4 Weeks
Nils Hoglander

Set for Season Debut Monday
Elias Pettersson

Misses Second Straight Game
Logan Cooley

Out Indefinitely
Brayden Point

Nikita Kucherov, Brayden Point Back for Lightning Monday
CFB

Anthony Hill Jr. Declaring for 2026 NFL Draft
CFB

Ryan Walters a Candidate for Tennessee Defensive Coordinator Job?
Trey Hendrickson

Set for Core-Muscle Surgery, Expected to Miss Around Six Weeks
Drake London

Considered Day-to-Day Going into Thursday Night
Jayden Daniels

No Long-Term Concerns for Jayden Daniels
Zach Ertz

MRI Confirms Season-Ending Torn ACL for Zach Ertz
Tee Higgins

Back in the Concussion Protocol
Riley Leonard

Week 15 Status Uncertain Due to Knee Injury
Mike Evans

Could Return on Thursday Night
De'Von Achane

May Require Rest This Week
Daniel Jones

' Season Over With Torn Achilles
Rory McIlroy

Ends 2025 as the Year's Most Unburdened Player
Aaron Rai

Needs to Figure Out Putting Woes This Offseason
Jordan Spieth

Plays Better on Paper in 2025 Than Results Show
Shedeur Sanders

Will Start for Browns the Rest of the Season
PGA

Chris Gotterup Needs to Find Better Touch and Consistency This Offseason
Hideki Matsuyama

Ends 2025 Season With a Bookend Victory
CFB

Tennessee Fires Defensive Coordinator Tim Banks
Scottie Scheffler

Comes Up Just Shy of Hero World Challenge Victory
Jordan Poole

Remains Sidelined on Monday
Merab Dvalishvili

Drops A Decision At UFC 323
Herbert Jones

Tagged as Questionable Against Spurs
Petr Yan

Reclaims Bantamweight Title
CeeDee Lamb

Progressing Well After Concussion
Stephon Castle

has a Chance to Return on Monday
Alexandre Pantoja

Era Ends With Gruesome Injury
Joshua Van

Becomes Second-Youngest UFC Champion
Dillon Brooks

Iffy for Monday Night
Brandon Moreno

Suffers His First TKO Loss
Brandon Moreno

Tatsuro Taira Becomes First Fighter To Finish Brandon Moreno
Garrett Wilson

No Timetable Yet for Garrett Wilson's Return
Henry Cejudo

Payton Talbott Retires Henry Cejudo
Henry Cejudo

Retires After UFC 323 Loss
Jan Blachowicz

Bogdan Guskov Vs. Jan Blachowicz Ends In A Majority Draw
Jan Blachowicz

And Bogdan Guskov Fight To Majority Draw
Dennis Schröder

Dennis Schroder Could Return on Monday Night
Keegan Murray

Listed as Questionable Vs. Pacers
CFB

Texas RB CJ Baxter Entering Transfer Portal
Mark Stone

Records Two Assists in Sunday's Win
Carter Hart

Defeats Rangers Sunday
Cutter Gauthier

Delivers Two Assists Sunday
Leo Carlsson

Nets Two Goals in Blowout Win
Logan Thompson

Posts First Shutout of the Season
Brayden Schenn

Leads Blues to Victory Sunday
Macklin Celebrini

Bags Three Points in Impressive Road Victory
San Francisco Giants

Jeff Kent Elected to Baseball Hall of Fame
Ketel Marte

Red Sox Interested in Trading for Ketel Marte
Kyle Schwarber

Pirates Make Four-Year Offer to Kyle Schwarber
CFB

Mississippi State, Rice Accept Bowl Bids as 5-7 Teams
CFB

Auburn, Florida State, Baylor Among Teams to Decline Bowl Bids
Paul George

Available on Sunday Evening
Joel Embiid

Available Against Lakers
Lauri Markkanen

Ruled Out Versus OKC
Jimmy Butler III

Officially Active on Sunday Night
CFB

Rob Aurich Set to Become Nebraska's Defensive Coordinator
LeBron James

Available Versus Philadelphia
MON

Samuel Montembeault Ruled Out for Sunday
Carter Hart

Available Against Rangers Sunday
Ryan Leonard

to Miss "Extended Period of Time"
John Carlson

a Game-Time Decision Sunday
Jordan Kyrou

Unavailable Against Canadiens
Matt Duchene

Set to Return Against Penguins
Pyotr Kochetkov

Back for Hurricanes Sunday
CFB

Notre Dame Opting Out of Postseason Amid College Football Playoff Exclusion
Karl-Anthony Towns

Ruled Out Against Orlando
Draymond Green

Remains on the Shelf Versus Chicago
Jimmy Butler III

Expected to Return on Sunday
Immanuel Quickley

Now Probable Versus Boston
Shai Gilgeous-Alexander

Will Miss First Game of the Year on Sunday
Joel Embiid

Upgraded to Probable Against Lakers
CFB

Kendal Briles a Candidate for South Carolina Offensive Coordinator Job
CFB

James Madison Playoff-Bound After Duke Wins ACC Title?
CFB

Notre Dame, Miami, Alabama on College Football Playoff Bubble
CFB

Brent Pry Could Return to Virginia Tech as Defensive Coordinator
Jose A. Ferrer

Mariners Acquire Jose A. Ferrer from the Nationals
Harry Ford

Traded to the Nationals
Cody Bellinger

Drawing Interest From the Phillies
MacKenzie Gore

Will the Nationals Trade MacKenzie Gore?
Byron Buxton

Twins Not Planning to Trade Joe Ryan, Byron Buxton
Petr Yan

Looks To Reclaim Bantamweight Belt
Merab Dvalishvili

Set For His Fourth Title Defense
Joshua Van

Can Become The New Flyweight Champion
Alexandre Pantoja

Set For Fifth Title Defense At UFC 323
Tatsuro Taira

Looks To Win Back-To-Back Fights
Brandon Moreno

Searches For His Third Win In A Row
Payton Talbott

A Favorite At UFC 323
Henry Cejudo

Set For His Retirement Fight
Jan Blachowicz

Set To Open Up UFC 323 Main Card
Bogdan Guskov

Looks To Extend His Win Streak
CFB

Emmett Johnson Leaving Nebraska for 2026 NFL Draft
CFB

Jam Miller Unlikely to Play in SEC Title Game
CFB

Penn State Expected to Hire Matt Campbell from Iowa State
CFB

Arkansas Targeting Ron Roberts for Defensive Coordinator Job
Jhostynxon Garcia

Pirates Acquire Jhostynxon Garcia From Red Sox
Cody Bellinger

Yankees Pushing Hard to Re-Sign Cody Bellinger
CFB

Penn State Eyeing Iowa State Coach Matt Campbell For Coaching Vacancy
Alex Bregman

Cubs Have Renewed Interest in Alex Bregman
CFB

Billy Napier Finalizing Deal to Become James Madison's New Head Coach
CFB

Buster Faulkner Set to Become Florida's New Offensive Coordinator
CFB

Joe Sloan Expected to be Kentucky's New Offensive Coordinator
Kyle Tucker

Visits With Blue Jays
Emilio Pagán

Reds Bring Back Closer Emilio Pagan on Two-Year Deal
Cedric Mullins

Rays Agree on One-Year Deal
Freddy Peralta

Brewers Considering Trading Freddy Peralta

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP