X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Daily Stats & Leaders
All Pitcher Matchups
Compare Any Players
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

Free MLB Betting Picks - Today's Best Bets, Expert Predictions, Odds (9/21/22)

Miles Mikolas - Fantasy Baseball Rankings, Draft Sleepers, MLB Injury News

John Brubaker's top MLB betting picks and best bets for today's MLB games on 9/21/22. His free picks against the spread, teasers, parlays, and MLB player props.

Happy Wednesday, RotoBallers, we're back for another week of MLB betting picks! Make sure you're following my Twitter, as I can't guarantee that I'll always be able to get the added plays written here in the article, but I will typically add whatever else I'm playing throughout the day. The entire RotoBaller team has been working around the clock to make sure we can get you guys the best betting picks, props, and lineups throughout the season. We're happy you're here with us and are looking forward to an extremely profitable 2022 season!

Attention fellow sports bettors! We have some exciting news to share as we are now officially partnered with various sportsbooks and have some sweet sports betting promo offers! Get your deposit bonus, as well as a year of free RotoBaller Premium access, when you sign up with a new account today! After you're signed up, use our picks in this article for spreads, totals, and props to win big.

If you're new, or just a refresher to those who read my articles last season, I'm John Brubaker. I've been betting MLB baseball games for four years now, and this is my second MLB season working with the great folks at RotoBaller. I've created my own betting model to help me create and identify value on run lines, totals, and money lines. In this article, I'll be providing my favorite betting picks for the MLB games on Wednesday, September 21, 2022.

Featured Promo: New Novig users get a $25 purchase match (50% discount up to $25) on your first Novig deposit, and a 3 free months of RotoBaller's "Big-4" Premium Pass (NFL, NBA, MLB, NHL) which includes exclusive tools for Betting, Props, DFS and more! CLAIM IT NOW

 

LucidMedia's 2022 MLB Betting Picks

  • Season to Date: 74-72-2, -15.43 units
  • Sides: 34-35-1, -12.72 units
  • Totals: 37-36-1, -4.41 units
  • Props: 1-0 +1.70 units

 

Today's MLB Betting Picks - Pirates @ Yankees

O/U: 8 | Moneyline: NYY -310

PIT: Roansy Contreras | NYY: Luis Severino

We finished 1-1 yesterday, as Kenley Jansen just couldn't stay out of trouble, allowing a run and effectively killing the Braves run line. That game ended up being a strange one and I'm sending positive vibes to Patrick Corbin, who left the game in the first inning.

We'll start the day off today with a first-inning under play in New York. The visiting Pirates will be sending Roansy Contreras (5-4, 3.24 ERA) to the mound. Contreras has been one of my favorites this year, considering he's been nothing short of perfect in the first inning this season. He's gone through each of his 15 starts, seven of which were on the road, without allowing a first-inning tally this season.

The Yankees will be sending Luis Severino (5-3, 3.45 ERA) to the mound. Severino has been solid both overall and the first inning this season, allowing a run in just two of nine starts in Yankee Stadium, and in just three of 13 starts overall. He should have no issue getting through a Pirates lineup that's been held scoreless in the opening frame in 82.3% of games overall, 84.2% on the road, and in eight of their last 10.

While FanDuel Sportsbook has the first inning under at -120, my model gives the under implied odds of 65.18%, good for "true" odds of -187. There's always the threat of an Aaron Judge home run in the bottom of the first, but I'll back Contreras to stay perfect under the bright lights of Yankee Stadium tonight.

Pick: Under 0.5 First Inning Runs (-120) FanDuel Sportsbook, 1 unit

 

Sports Betting Promo Offers

Featured Promo: Get any Betting Premium Pass for 50% off using code THANKS. Win more with exclusive betting picks from proven winners across 9 sports! Find optimal bets with our Betting Picks Tool and Bet Weighting Tool and follow along in our VIP chat rooms! Go Premium, Win More!

 

Today's MLB Betting Picks - Cardinals @ Padres

O/U: 7.5 | Moneyline: SD -123

STL: Miles Mikolas | SD: Blake Snell

We'll head out West to San Diego for another first inning under. We'll back Cardinals right-hander Miles Mikolas (11-12, 3.46 ERA). It's kind of shocking that Mikolas has accrued so many losses this season, given how well he's pitching and how well the Cardinals have played. Nevertheless, he's allowed a first-inning run in just two of 16 starts on the road as well as six of 30 starts overall. 

He'll match up with San Diego southpaw Blake Snell (7-9, 3.85 ERA). Snell has had a pretty solid bounce-back season for the Padres this year and has been excellent in the first inning. First-inning tallies have been few and far between with Snell on the mound, as he's allowed one in just two of 12 starts at Petco Park and in just three of 21 starts overall.

Despite both of these offenses (likely) leading their respective clubs to the playoffs, they haven't jumped on opposing pitchers in the first inning too often. The Cardinals have scored in roughly 32.4% of first innings overall, but that number drops to just 25.7% when on the road. The Padres on the other hand have scored in 24% of first innings overall and in 26.1% of first innings at home. The Cardinals have been held scoreless in nine of their last 10 while the Padres have been held scoreless in eight of their last 10.

FanDuel Sportsbook has the first inning under at -138, which is a surprising number given the low game total of 7.5. We'll take this value though, considering my model gives the under a 63.73% chance of hitting, good for "true" odds of -176. Let's avenge the unfortunate Braves loss last evening and go 2-0 today.

Pick: Under 0.5 First Inning Runs (-138) FanDuel Sportsbook, 1 unit

Good luck, RotoBallers, and make sure to follow my Twitter for more plays. Talk to you tomorrow!



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy baseball app for iPhone and Android with 24x7 player news, injury alerts, sleepers, prospects & more. All free!



More Fantasy Baseball Analysis




POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Daily Stats & Leaders
All Pitcher Matchups
Compare Any Players
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Chris Boucher

Active Thursday vs. Kings
Jalen Duren

Won't Return Thursday After Ankle Injury
Ryan Kalkbrenner

Ruled Out Again Friday
Josh Hart

Sidelined for Fourth Straight Game
Kyshawn George

to Miss Fourth Straight Game Friday
Joel Embiid

Cleared to Play Thursday vs. Mavericks
Jonas Valančiūnas

Jonas Valanciunas Ruled Out for At Least Four Weeks
Bo Bichette

Yankees Showing Interest in Bo Bichette
D'Angelo Russell

Ruled Out Thursday With Illness
George Kittle

Listed as Questionable for Week 18
Alperen Sengün

Alperen Sengun Active Versus Nets
Amon-Ra St. Brown

Trending Towards Playing
Clint Capela

Steven Adams and Clint Capela Sidelined Thursday
Miles Wood

Blue Jackets Place Miles Wood on Injured Reserve
Dak Prescott

May Not Play Full Game in Week 18
Conor Garland

to Miss One Week
Egor Demin

Won't Suit Up Against Houston
Marco Rossi

to Miss at Least One Week
Ace Bailey

Still Out on Thursday Night
Tari Eason

Active on Thursday
Yegor Chinakhov

Set for Penguins Debut Thursday
Lauri Markkanen

Ruled Out on Thursday
Tanner McKee

Will Start for Eagles in Week 18
Shayne Gostisbehere

Misses Third Consecutive Game Thursday
Keyonte George

Unavailable on Thursday
Michael Porter Jr.

Out on Thursday
Auston Matthews

Returns From One-Game Absence
Josh Allen

Trending Towards Resting in Week 18
William Nylander

Remains Out Thursday
Lamar Jackson

Will Officially Return in Week 18
Tobias Harris

Won't Suit Up Against Miami
Lauri Markkanen

on the Injury Report for Thursday Night
Keyonte George

Battling an Illness, Might Miss Thursday's Game
Jusuf Nurkić

Jusuf Nurkic Won't Play on Thursday Evening
Houston Astros

Astros Sign Tatsuya Imai to Three-Year Deal
Jordan Love

Clears Concussion Protocol, Won't Start in Week 18
George Kittle

"Absolutely" Expects to Play in Week 18
Clayton Tune

to Start for Packers in Week 18
Chris Olave

Ruled Out for Week 18
Tom Wilson

Wraps Up 2025 With Gordie Howe Hat Trick
Valeri Nichushkin

Nets Second Career Hat Trick
Frank Vatrano

to Miss Six Weeks With Shoulder Injury
Conor Sheary

Noah Laba Exit With Injuries Wednesday
Brayden McNabb

Suffers Upper-Body Injury Wednesday
Miles Wood

Exits Early Wednesday
Gavin Brindley

Sustains Upper-Body Injury
Michael Porter Jr.

Battling Illness, Questionable Thursday
Davante Adams

Not Expected to Play in Week 18
Geno Smith

Won't Play in Week 18
Aaron Rodgers

Considering Playing Beyond 2025?
Sean Monahan

Sits Out Wednesday's Game
Zach Werenski

Misses Fourth Straight Game Wednesday
Dougie Hamilton

Questionable Wednesday
Radko Gudas

Expected to Remain Out Wednesday
Stefon Diggs

Expected to Play in Week 18
Ilya Lyubushkin

Back From One-Game Absence Wednesday
Alex Lyon

to Miss "Bit of Time"
Erik Cernak

Rejoins Lightning Lineup Wednesday
Christian McCaffrey

Trending to Play in Week 18
Jalen Hurts

Eagles Expected to Rest Jalen Hurts, Most Starters in Week 18
George Kittle

49ers Will be "Very Surprised" if George Kittle Doesn't Play on Saturday
Marvin Harrison Jr.

Ruled Out for Regular-Season Finale
CFB

Lane Kiffin Interested in Sam Leavitt, Brendan Sorsby at LSU
CFB

Deuce Knight Officially Entering Transfer Portal
CFB

Kewan Lacy Expected to Be Full-Go Against Georgia
Stefon Diggs

Facing Strangulation, Assault Charges
CFB

Chip Kelly Named Northwestern Offensive Coordinator
Riley Leonard

Will Start Against the Texans
Bijan Robinson

Explodes for 229 Total Yards, Two Touchdowns on Monday Night
CFB

Penn State Working to Hire D'Anton Lynn as Next Defensive Coordinator
CFB

Omar Cooper Expected to be Full-Go for Rose Bowl
CFB

Marcus Freeman Staying with Notre Dame for 2026 Season
CFB

Star Wideout Cam Coleman Entering Transfer Portal
CFB

Jay Hill Expected to be Next Michigan Defensive Coordinator

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP