👉 TAP TO SAVE 30% WITH CODE NEW
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

#1 Expert Projections
Save 30% Now
Import Your Leagues
Top-Rated Accuracy
Draft Simulator
Enter League Settings
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

Free MLB Betting Picks - Today's Best Bets, Expert Predictions, Odds (5/25/22)

Mike Trout - Fantasy Baseball Rankings, MLB Injury News, DFS and Betting Picks

Mark Kieffer's top MLB betting picks and best bets for today's MLB games on 5/25/22. His free picks against the spread, teasers, parlays, and MLB player props.

Welcome back, RotoBallers! I am Mark and this is my second season writing MLB content on RotoBaller. In this article, I'll be providing my favorite betting picks MLB games on Wednesday, May 25, 2022, for the seven-game 6:40 PM Eastern slate.

This article will be focused on sides and totals. I am a huge baseball fan and baseball has been my bread and butter for the last couple of decades. Hopefully, I can help you win some pizza money! I occasionally will post some ideas and picks with bets, DFS, and other things on my Twitter account. You can follow me at @Mark_Kieffer

Attention fellow sports bettors! We have some exciting news to share as we are now officially partnered with various sportsbooks and have some sweet sports betting promo offers! Get your deposit bonus, as well as a year of free RotoBaller Premium access, when you sign up with a new account today! After you're signed up, use our picks in this article for spreads, totals, and props to win big.

Featured Promo: New Novig users get a $25 purchase match (50% discount up to $25) on your first Novig deposit, and 6 free months of RotoBaller's "Big-4" Premium Pass (NFL, NBA, MLB, NHL) which includes exclusive tools for Betting, Props, DFS and more! CLAIM IT NOW

 

Mark's 2022 MLB Betting Picks

With these articles, I am 13-23-2 overall on the season, down 3.77 units. I have been starting small and conservative because it's a long season. It has been frustratingly difficult to predict the outcome of games in part due to the ball but we have to keep grinding, it's a long season, and eventually, we will get in the black.

 

Boston Red Sox @ Chicago White Sox

O/U: 8 | Moneyline: CHW -175
BOS: Rich Hill| CHW: Lucas Giolito

We have Rich Hill against Lucas Giolito tonight, meaning it's a slam dunk that the White Sox win right? Not so fast.

While Giolito is obviously the better pitcher, with a 2.67 xFIP and a 34.6% strikeout rate, the rest of the team is somewhat shaky. First, the offense. Yes, they have been playing better, but this still is not a great offense right now. They have scored the third-fewest runs in baseball, they have the fifth-lowest ISO (.125), and they have the lowest walk rate in the game. Additionally, their bullpen ERA of 4.28 is the eighth-worst in the game too.

Looking at the Red Sox, yes they are outmatched at starting pitcher but the rest of the team looks better. They are 10th in runs scored and ninth in ISO (.153). Their bullpen ERA is middle of the league with a 3.78 ERA.

Boston has the better lineup and better bullpen but is this large of an underdog? It doesn't make sense.

Pick: Red Sox Moneyline (+152), WynnBet Sportsbook, 0.5 unit

 

Philadelphia Phillies @ Atlanta Braves

O/U: 8.5 | Moneyline: ATL -150
PHI: Ranger Suarez | ATL: Charlie Morton

The analysis for this game will be straight to the point. This should be a high-scoring game. Ranger Suarez has a 4.02 xFIP. Charlie Morton has a 4.76 xFIP. The Phillies' bullpen ERA is 4.15 -- bottom-10 in the league. Offensively, the Phillies have scored the eighth-most runs in the league with the eighth highest ISO. The Braves have scored the 17th-most runs in the league but have the seventh-highest ISO in the league. There are some weather concerns, but if this game plays, it will be difficult to not see runs scored at a high rate tonight.

Pick: OVER 8.5 Runs (-110), Pointsbet Sportsbook, 0.5 units

 

Texas Rangers @ Los Angeles Angels

O/U: 8.5 | Moneyline: LAA -159
PHI: Glenn Otto| LAA: Reid Detmers

Glenn Otto has a 4.88 xFIP with a K-BB% of just 4.6%. He is going to face the Angels, the team with the most runs scored in the American League, and the team with the third-highest ISO in all of baseball. He will be backed by a middle-of-the-road bullpen with a 3.66 ERA and 22 home runs allowed. In DFS, the Angels should be the most popular team rostered.

Los Angeles is going to start Reid Detmers. Detmers has a 4.44 xFIP and a 10.4% K-BB% and has allowed an HR/9 of 1.30 this year. He isn't the type of pitcher teams are afraid of either. Texas has not performed well offensively, they have scored the 22nd- most runs in baseball and have just the 22nd-highest ISO in baseball. When facing average to below-average pitchers, sometimes below-average offenses do well, though. The Angels bullpen is middle of the road as well with a 3.82 ERA.

In addition to the pitching matchup being one that hitters should get excited about, the weather here will be nice: 70 degrees and the wind blowing out to left field. This is a great run-scoring environment and I believe just that will happen.

Pick: OVER 8.5 Runs (-110), Pointsbet Sportsbook, 0.5 units

Good luck, RotoBallers! Stay tuned for more great DFS and betting content throughout the week!



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy baseball app for iPhone and Android with 24x7 player news, injury alerts, sleepers, prospects & more. All free!



More Fantasy Baseball Analysis




POPULAR FANTASY TOOLS

#1 Expert Projections
Save 30% Now
Import Your Leagues
Top-Rated Accuracy
Draft Simulator
Enter League Settings
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Myles Garrett

Browns Modify Myles Garrett's Contract
Kyle Pitts Sr.

Remains a Risky Tight End Option Despite 2025 Breakout
Dalton Schultz

Upside Remains Limited Despite Resurgent 2025 Production
Kimani Vidal

Could Be Sliding Down the Running Back Depth Chart in Los Angeles
Juwan Johnson

Can Juwan Johnson Repeat Steady 2025 Production in 2026?
Jackson Chourio

Placed on Injured List with Fractured Hand
Francisco Lindor

Officially Starting on Opening Day
Tank Dell

Can Tank Dell Re-Establish His Career Coming Off His Serious Injury?
Chuba Hubbard

Has Chuba Hubbard Reclaimed the RB1 Role in Carolina?
Keegan Murray

Cleared for Basketball Activities
Killian Hayes

Uncertain for Thursday
Precious Achiuwa

Questionable Thursday
Jalen Suggs

Could Miss Third Consecutive Game
Anthony Black

Misses 11th Straight Game
Franz Wagner

Remains Out Thursday
Anthony Edwards

Could Return Saturday
Mika Zibanejad

Pots Two Goals Versus Toronto
Pavel Zacha

Adds Two More Points Against Buffalo
Jordan Addison

in Line for 2026 Resurgence with Improved Quarterback Play?
Landry Shamet

to Remain Out Thursday
Gunnar Helm

Appears Well-Positioned for 2026 Breakout
Vít Krejčí

Vit Krejci Misses Sixth Straight Game
Peyton Watson

Good to Go Wednesday
Dalton Kincaid

Facing Durability and Usage Questions Heading into 2026
Aaron Gordon

Misses Second Leg of Back-to-Back
Jakob Poeltl

Cleared to Play Against Clippers
Colston Loveland

Poised for Superstar Breakout in 2026?
Immanuel Quickley

Won't Play Wednesday
Brandon Ingram

Active Against Clippers
Khalil Shakir

Could See His Role in Buffalo Shrink in 2026
Myles Turner

Won't Play Against Trail Blazers
Bobby Portis

Kyle Kuzma Out Wednesday
Brandon Williams

Available Wednesday Night
Kawhi Leonard

Ready to Face Raptors
Daniel Gafford

Won't Play Wednesday
Jerami Grant

Returns to Action Wednesday
Robert Williams III

Active Wednesday Night
Christian Watson

Is Christian Watson's Breakout Season Coming in 2026?
Pat Freiermuth

Should Have More Volume, but QB Situation Still a Mystery
Nicolas Roy

to Be Out For "a Little Bit"
Anton Lundell

Likely Out for Rest of Regular Season
Anthony Mantha

Day-to-Day With Lower-Body Injury
Evgeni Malkin

to Remain Out Thursday
Mattias Samuelsson

a Game-Time Call Wednesday
Jonathan Quick

Remains Unavailable Wednesday
Victor Hedman

Takes Leave of Absence
Jake Bates

Lions Officially Re-Sign Jake Bates
Patrick Mahomes

Chiefs "Optimistic" That Patrick Mahomes Can Take Part in Offseason Practices
Najee Harris

Visits With Seahawks
Sean Murphy

Lands on 10-Day Injured List
Bryce Miller

Placed on 15-Day Injured List With Oblique Strain
Lars Nootbaar

Will Begin the Season on 60-Day Injured List
Jackson Holliday

Placed on 10-Day Injured List
New York Jets

Ty Simpson to Hold Private Workout With Jets on Friday
Ronnie Rivers

Rams Re-Sign Ronnie Rivers to One-Year Deal
Las Vegas Raiders

Raiders to Host Fernando Mendoza for a Top-30 Visit in Two Weeks
Tua Tagovailoa

Open to Being a QB Mentor in Atlanta
Jeremy Peña

Jeremy Pena on the Astros Opening Day Roster
Blake Snell

Dodgers Place Blake Snell on 15-Day Injured List
John Carlson

Sets Up Three Goals Tuesday Night
Joel Hofer

Picks Up Sixth Shutout of the Season
John Tavares

Records Three Assists in Tuesday's Win
NJ

Arseni Gritsyuk Scheduled for Imaging Wednesday
Tony DeAngelo

Suffers Lower-Body Injury Tuesday
Emmitt Finnie

Enters Concussion Protocol
Ryan Fox

a High-Upside Value in Houston
Barrett Hayton

Sustains Upper-Body Injury Tuesday
Marco Penge

a Boom-or-Bust Option in Houston
Aaron Rai

Looks to Bounce Back in Houston
Jason Day

a Volatile Option at the Texas Children's Houston Open
Kirby Yates

Angels Place Kirby Yates on 15-Day Injured List
Harris English

Eyes a Bounce-Back at the Texas Children's Houston Open
Ben Griffin

Looks for Turnaround at the Texas Children's Houston Open
Rickie Fowler

Brings Strong Form Into Texas Children's Houston Open
Brady Tkachuk

Collects Two More Points on Tuesday
Martin Necas

Scores Twice Against Penguins
Nick Lodolo

Will Open 2026 on the Injured List Due to Finger Ailment
Pete Crow-Armstrong

Agrees to Six-Year, $115 Million Extension With the Cubs
Igor Chernyshov

Returns to Sharks Lineup
Dylan Larkin

Good to Go Tuesday
Ross Colton

Logan O'Connor, Ross Colton Available Tuesday
Francisco Lindor

Likely to be Ready for Opening Day
Ryan Gerard

Can Continue Rolling at Texas Children's Houston Open
Pierceson Coody

Bounces Back at Valspar Championship
Rasmus Hojgaard

Trying to Get Back on Track at Texas Children's Houston Open
Michael Thorbjornsen

Playing Well Heading to Texas Children's Houston Open
Harry Hall

Looking for Consistency at Texas Children's Houston Open
Brooks Koepka

Continues Building Momentum
Roki Sasaki

to Stick in Rotation Despite Spring Struggles
Kevin McGonigle

Makes Tigers Opening Day Roster
Scottie Scheffler

Withdraws From Texas Children's Houston Open
Ryan Pepiot

Placed on Injured List to Open the Season
J.J. Wetherholt

JJ Wetherholt Likely to Hit Leadoff on Opening Day
Connelly Early

to Make First Start on Sunday
Luke Clanton

Might Have a Problem in Houston
Sam Stevens

Happy to See Houston This Week
Keith Mitchell

Tries to Rebound After The Players Championship
Will Zalatoris

Returning This Week at Houston
Wyndham Clark

Trending in the Wrong Direction Heading to Houston
Shane Lowry

Seeking Better Luck in Houston This Weekend
Kurt Kitayama

Poised to Bounce Back at the Houston Open
Pete Crow-Armstrong

Cubs, Pete Crow-Armstrong Finalizing Long-Term Extension
Blake Snell

Targeting a May Return
Hunter Greene

Reds Place Hunter Greene on 60-Day Injured List
J.J. Wetherholt

JJ Wetherholt Makes Cardinals Opening Day Roster
Lerone Murphy

Suffers His First Loss
Movsar Evloev

Edges Out Lerone Murphy
CFB

Notre Dame Ranks No. 1 in Returning Production for 2026
Michael Aswell

Jr. Drops Decision At UFC London
Michael Aswell

Luke Riley Outclasses Michael Aswell Jr.
Sam Patterson

Suffers Unanimous-Decision Loss
Michael Page

Wins Lackluster Decision
Austen Lane

Suffers First-Round TKO Loss
Iwo Baraniewski

Delivers 28-Second TKO
Tyler Reddick

Overcomes Adversity for Fourth Victory of the Season At Darlington
Brad Keselowski

Falls Short of Darlington Victory Despite Domination
Ryan Blaney

Recovers From Pit-Road Struggles to Score Career-Best Darlington Finish
Carson Hocevar

Rallies to Finish Fourth at Darlington
Kyle Larson

Decent Performance Ends with Technical Issues At Darlington
Tyler Reddick

the Clear Favorite at Darlington
Kyle Larson

a High-Risk, High-Reward Driver at Darlington
Ryan Blaney

Is Getting Better at Darlington
NASCAR

Bubba Wallace Not Slowing Down at Darlington
Chris Buescher

Should be a Top-10 Contender at Darlington
Austin Cindric

a Sleeper at Darlington
Erik Jones

Quickest in Practice at Darlington
Denny Hamlin

Qualifies Ninth for this Week's Cup Race at Darlington
Chase Briscoe

Is One of the Top DFS Options of the Week for Darlington
William Byron

Is William Byron A Playable DFS Option for Darlington Lineups?
Christopher Bell

Could Christopher Bell be Considered A Decent DFS Option for Darlington?
Chase Elliott

Is Chase Elliott Worth Rostering At Darlington This Week For DFS?
Joey Logano

May Not Have the Speed to Warrant A Darlington DFS Lineup Spot
Ross Chastain

Should DFS Players Trust Ross Chastain at Darlington?
Kyle Busch

Could Kyle Busch Be A Worthy DFS Option for Darlington?
Brad Keselowski

May be A Contriarian DFS Tournament Option At Darlington
Lerone Murphy

Set For UFC London Main Event
Movsar Evloev

Looks To Remain Unbeaten
Michael Aswell

Jr. An Underdog At UFC London
Luke Riley

Set For UFC London Co-Main Event
Sam Patterson

Looks To Extend His Win Streak
Michael Page

Set For Welterweight Bout
Austen Lane

In Dire Need Of Victory
Iwo Baraniewski

A Favorite At UFC London
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF