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FantasyDraft Lineup Picks (Week 10) - NFL DFS Advice

It is finally time for NFL Week 10! If you're a FantasyDraft DFS player, then this article is for you.

Each week, I will be providing you with my daily fantasy football lineup picks for FantasyDraft. The lineup picks will range from some of the elite players to mid-priced options and value plays.

If you have any questions or comments, feel free to hit me up on Twitter @BalesSJustin.

 

FantasyDraft - DFS Quarterback Pick

Dak Prescott at ATL ($13,300)

Prescott has been playing at an elite level recently. He was not needed in a rainy game against the Redskins, but he has played well in each of his five games aside from that outlier. In those five games, Prescott is averaging 26.8 fantasy points per game. He gets a good matchup against Atlanta, who have been an average defense against the quarterback this season. This game is also expected to stay close, and Prescott can be used in all leagues.

 

FantasyDraft - DFS Running Back Picks

Le'Veon Bell at IND ($17,800)

Bell has been playing at an elite level this season. He's averaging 122.4 total yards and 0.6 touchdowns on 28.6 touches per game. He is the focal point of the Steelers offense, and he gets an elite matchup against the Indianapolis Colts, who have struggled against the run and pass this season. The Steelers are -10 point favorites in this game, suggesting they could run out the clock for the majority of the second half. Bell will see the majority of those touches, making him an elite option.

Lamar Miller at LAR ($9,500)

Miller has struggled at times this season, but he has recorded at least 15 touches in seven of his eight games this season. He gets an elite matchup against the Los Angeles Rams, who are allowing 121.6 rushing yards per game this season. They have also allowed eight rushing touchdowns. Miller is not an elite running back in the NFL, but he comes with a reasonable price tag, and he makes an elite tournament option this week.

 

FantasyDraft - DFS Wide Receiver Picks

Antonio Brown at IND ($17,900)

Brown has struggled with efficiency this season, as his catch rate and touchdown rate are lower than his career averages. Still, Brown is averaging a 7.1/103.4/0.4 line on 11.8 targets per game. The Colts have opted to cut Vontae Davis this week, meaning they will have a replacement level talent cornerback trying to keep up with Brown. He is an elite option in all leagues, even with the high price tag.

Demaryius Thomas vs NE ($10,700)

Thomas is an interesting option this week. The New England Patriots have been one of the worst defenses in the NFL this season. Thomas is one of the biggest beneficiaries of the Denver quarterback change, recording 12 targets in his only game with Brock Osweiler. He should be peppered with targets once again this week, making him a great option for his current price tag.

 

FantasyDraft - DFS Tight End Pick

Garrett Celek vs NYG ($5,000)

Celek is expected to draw the start for George Kittle this week. Last week, Celek saw four targets in limited playing time. He gets an elite matchup against the New York Giants, who rank 32nd in the NFL against the tight end. They have been allowing touchdowns to tight ends at an elite rate this season. Celek comes with an extremely low price tag, and he is an elite option in all leagues.

 

FantasyDraft - DFS Defense Pick

Chicago Bears D/ST vs GB ($5,100)

The Bears defense has quietly been playing extremely well this season. They are averaging 1.4 turnovers and 2.9 sacks per game this season. They have also scored three defensive touchdowns this season, as well. They get a great matchup against the Green Bay Packers, who have been struggling without Aaron Rodgers. The Bears are also -5.5 point favorites in a game set at only 38, giving Green Bay a low implied team total of 16.3 points. Chicago's defense could fly under the radar this week, but they can be used in all leagues.

 

More Week 10 DFS Analysis

 

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REAL-TIME FANTASY NEWS

Noah Fant

Profiles as a Dynasty Drop Candidate Entering 2026
Rashee Rice

Andy Reid Expects Rashee Rice to be Ready for Training Camp
Jordyn Tyson

Remains Limited in OTAs on Thursday
Tank Dell

Not Participating in Texans OTAs
Jacoby Brissett

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Darnell Washington

Participating in OTAs
Jaylen Warren

Slims Down Over the Offseason
Jaxson Dart

Addresses Teammates to Discuss his Involvement With President Trump
Garrett Wilson

Back at OTAs With Jets
Brock Bowers

Taking Part in OTA Workouts
MLB

MLB Proposes Hard Salary Cap as Part of Next CBA
Xavier Worthy

Limited in OTAs After Having Shoulder Surgery
Patrick Mahomes

Limited to 7-on-7 Drills at OTAs
Joe Burrow

Solidified as a Top Dynasty Quarterback?
Jordan Love

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Dalton Schultz

Can Dalton Schultz Have Another Top-10 Season?
Jayden Higgins

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Luther Burden III

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a Low-Cost Dynasty Depth Piece
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Jonas Valanciunas Attracting Interest From Europe
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Reportedly Waiting for Lakers Approach
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Lane Hutson Struggles in Game 4 Loss
CAR

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Sebastian Aho Pots Game-Winner on Power Play
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Nikolaj Ehlers Tallies Two Helpers in Impressive Road Win
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Shayne Gostisbehere Records Two Assists in Game 4 Win
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Frederik Andersen Establishes Hurricanes New Postseason Shutout Record
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Continues Homer Barrage With Two More Long Balls on Wednesday
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Cristopher Sanchez Makes History With Seven More Shutout Innings Against Padres
Teoscar Hernández

Teoscar Hernandez Lifted From Wednesday's Game Early With Hamstring Strain
Kenley Jansen

Exits Relief Appearance on Wednesday With Groin Injury
Mason Plumlee

NBA Upgrades Mason Plumlee's Foul to a Flagrant 1
Victor Wembanyama

Receives Warning From NBA
Atlanta Hawks

Hawks Promote Onsi Saleh to President of Basketball Operations
Jalen Williams

Listed as Questionable for Game 6
Ajay Mitchell

Ruled Out for Game 6
Eury Pérez

Eury Perez Pulled Early on Wednesday With Hamstring Issue
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Drew Mestemaker a Top Big 12 Quarterback Right Away?
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Sungjae Im Remains Boom-or-Bust at Colonial
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Michael Thorbjornsen Trending in Wrong Direction Entering Colonial
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Limited to Nine Points in Game 5 Loss
Russell Henley

a Top Option at Colonial
Harry Hall

Hoping Putter Carries Him at Colonial
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Notches 22 Points With Four Triples Tuesday
Stephon Castle

Leads Spurs in Scoring Tuesday Night
Rickie Fowler

Looks to Regain Momentum at Colonial
Victor Wembanyama

Struggles in Game 5 Loss to Thunder
Alex Caruso

a Difference-Maker Again in Game 5
Pierceson Coody

Looking to Stay Hot at Colonial
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Scores Game-High 32 Points in Game 5 Win
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Scores Series-Clincher Tuesday Night
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Comes Off Awful Putting Performance at PGA Championship
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Faces Different Test at the Colonial
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Seeks Better Beginning in Fort Worth
Tom Hoge

Ups and Downs Could Continue at Colonial
Brian Harman

Not Having the Best Golf Season in 2026
Austin Eckroat

Struggling Too Often Heading to Charles Schwab Challenge
Zach Bauchou

Tries to Keep Momentum Rolling at Colonial
Keegan Bradley

Looking to Rebound at Colonial
Jared McCain

Moves into Starting Five
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Joe Mazzulla Wins Coach of the Year
Jalen Williams

is Ruled Out for Game 5 on Tuesday
Zion Williamson

to See More Versatile Role
Cleveland Cavaliers

Kenny Atkinson to Remain Cavaliers Head Coach Next Season
Claude Giroux

Planning to Return for 20th NHL Campaign
Carter Hart

Aiming for Sixth Consecutive Win Tuesday
Evgeni Malkin

Inks New One-Year Deal With Penguins
Mackenzie Blackwood

in Net for Game 4 Against Golden Knights
Valeri Nichushkin

a Game-Time Call Tuesday
Nathan MacKinnon

Will Suit Up Tuesday
Ben Griffin

Looking to Repeat This Week at Colonial
Rasmus Hojgaard

a Player to Avoid at Charles Schwab Challenge
Hideki Matsuyama

Needs Solid Driving Week at Charles Schwab Challenge
Justin Thomas

Trending Well Ahead of Charles Schwab Challenge
Akshay Bhatia

Lacking Driving Prowess Needed at Colonial Country Club
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Josh Hoover Tasked With Leading Indiana Back to the Playoffs
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Braylon Staley the Next 1,000-Yard Tennessee Receiver?
CFB

Ahmad Hardy's Return Timeline Remains Unclear
Ivan Demidov

Contributes an Assist in Losing Effort
Lane Hutson

Records Power-Play Goal in Game 3 Loss
Frederik Andersen

Enjoys Another Easy Night at the Office in Game 3
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Tatsuya Imai

Two Relievers Combine to No-Hit the Rangers on Monday
Dylan Cease

Heading to Injured List With Hamstring Injury
Daniel Suarez

Wins at Charlotte in Rain-Shortened Coca-Cola 600
Christopher Bell

Finishes as the Runner-Up in the Coca-Cola 600 at Charlotte
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Falls Short of Winning and Places Third at Charlotte
Tyler Reddick

Places Fourth After Leading Laps at Charlotte
Kyle Larson

Strong and Consistent Day Ends in Fifth at Charlotte
Dylan Cease

Removed From Sunday's Start With Hamstring Discomfort
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Exits Sunday's Game Early with Elbow Contusion
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Reds-Cardinals Game Postponed on Sunday
Edward Cabrera

Cubs Place Edward Cabrera on the 15-Day Injured List
Denny Hamlin

the Favorite to Win at Charlotte
Tyler Reddick

on Pole for Coca-Cola 600
Christopher Bell

Could Break Out of Slump
Kyle Larson

May have A Solid Day at Charlotte
Ryan Blaney

Is A DFS Risk for Charlotte Lineups
William Byron

Could have A Great DFS Performance at Charlotte
Chase Briscoe

Is A Solid Tournament Option for Charlotte DFS Lineups
Ty Gibbs

May not be Worth his Salary for Charlotte DFS Lineups
Chris Buescher

May be a Sneaky Tournament Option for Charlotte Lineups
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Bubba Wallace Has Favorable Upside for Charlotte DFS Lineups
Ross Chastain

Is A Strong Addition for DFS Lineups at Charlotte
Austin Dillon

Should Fantasy Managers Roster Austin Dillon for Charlotte DFS Lineups?
Chase Elliott

Should Be Strong at Charlotte
Carson Hocevar

Confident for Coca-Cola 600
Corey Heim

a Chalk DFS Pick at Charlotte
Michael McDowell

Is Michael McDowell A Tournament Option for Charlotte Lineups?
MLB

Orioles-Tigers Game Postponed on Saturday
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Rays-Yankees Postponed on Saturday
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Heads to Injured List With Ankle Sprain
Jackson Merrill

has Sore Ribs, Expected to Avoid Injured List
RANKINGS
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