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FantasyDraft Lineup Picks (Week 10) - NFL DFS Advice

It is finally time for NFL Week 10! If you're a FantasyDraft DFS player, then this article is for you.

Each week, I will be providing you with my daily fantasy football lineup picks for FantasyDraft. The lineup picks will range from some of the elite players to mid-priced options and value plays.

If you have any questions or comments, feel free to hit me up on Twitter @BalesSJustin.

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FantasyDraft - DFS Quarterback Pick

Dak Prescott at ATL ($13,300)

Prescott has been playing at an elite level recently. He was not needed in a rainy game against the Redskins, but he has played well in each of his five games aside from that outlier. In those five games, Prescott is averaging 26.8 fantasy points per game. He gets a good matchup against Atlanta, who have been an average defense against the quarterback this season. This game is also expected to stay close, and Prescott can be used in all leagues.

 

FantasyDraft - DFS Running Back Picks

Le'Veon Bell at IND ($17,800)

Bell has been playing at an elite level this season. He's averaging 122.4 total yards and 0.6 touchdowns on 28.6 touches per game. He is the focal point of the Steelers offense, and he gets an elite matchup against the Indianapolis Colts, who have struggled against the run and pass this season. The Steelers are -10 point favorites in this game, suggesting they could run out the clock for the majority of the second half. Bell will see the majority of those touches, making him an elite option.

Lamar Miller at LAR ($9,500)

Miller has struggled at times this season, but he has recorded at least 15 touches in seven of his eight games this season. He gets an elite matchup against the Los Angeles Rams, who are allowing 121.6 rushing yards per game this season. They have also allowed eight rushing touchdowns. Miller is not an elite running back in the NFL, but he comes with a reasonable price tag, and he makes an elite tournament option this week.

 

FantasyDraft - DFS Wide Receiver Picks

Antonio Brown at IND ($17,900)

Brown has struggled with efficiency this season, as his catch rate and touchdown rate are lower than his career averages. Still, Brown is averaging a 7.1/103.4/0.4 line on 11.8 targets per game. The Colts have opted to cut Vontae Davis this week, meaning they will have a replacement level talent cornerback trying to keep up with Brown. He is an elite option in all leagues, even with the high price tag.

Demaryius Thomas vs NE ($10,700)

Thomas is an interesting option this week. The New England Patriots have been one of the worst defenses in the NFL this season. Thomas is one of the biggest beneficiaries of the Denver quarterback change, recording 12 targets in his only game with Brock Osweiler. He should be peppered with targets once again this week, making him a great option for his current price tag.

 

FantasyDraft - DFS Tight End Pick

Garrett Celek vs NYG ($5,000)

Celek is expected to draw the start for George Kittle this week. Last week, Celek saw four targets in limited playing time. He gets an elite matchup against the New York Giants, who rank 32nd in the NFL against the tight end. They have been allowing touchdowns to tight ends at an elite rate this season. Celek comes with an extremely low price tag, and he is an elite option in all leagues.

 

FantasyDraft - DFS Defense Pick

Chicago Bears D/ST vs GB ($5,100)

The Bears defense has quietly been playing extremely well this season. They are averaging 1.4 turnovers and 2.9 sacks per game this season. They have also scored three defensive touchdowns this season, as well. They get a great matchup against the Green Bay Packers, who have been struggling without Aaron Rodgers. The Bears are also -5.5 point favorites in a game set at only 38, giving Green Bay a low implied team total of 16.3 points. Chicago's defense could fly under the radar this week, but they can be used in all leagues.

 

More Week 10 DFS Analysis

 

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REAL-TIME FANTASY NEWS

Edward Cabrera

Cubs Finalizing Deal to Acquire Edward Cabrera From Marlins
New York Giants

Giants "All-In" on Hiring John Harbaugh
CFB

Jackson Arnold Signs with UNLV
CFB

Sam Leavitt Scheduled to Visit Tennessee
Devon Toews

to Miss at Least Two Weeks
Gabriel Landeskog

Out for Several Weeks
Jamie Drysdale

Makes Early Exit Tuesday
Bobby Brink

Injured in Tuesday's Win
Adam Henrique

Expected to Miss Time
Brad Marchand

Dealing With Lingering Health Issue
Haydn Fleury

Hospitalized Tuesday
Moussa Diabaté

Ryan Kalkbrenner Out, Moussa Diabate Probable Wednesday
Brandon Miller

Listed as Probable Wednesday
Alex Caruso

Absent for Second Consecutive Game
Nicolas Claxton

Available Wednesday
Moritz Wagner

Still Out Wednesday
Franz Wagner

Not Ready to Return Wednesday
Jalen Suggs

Remains Out Wednesday
Draymond Green

Questionable to Suit Up Wednesday
Jalen Smith

Ruled Out for Second Straight Game
Matas Buzelis

Could Miss First Game of the Season Wednesday
Coby White

May Skip Wednesday's Game
Cade Cunningham

Probable for Wednesday
Isaiah Hartenstein

to Remain Out Wednesday
Kelly Oubre Jr.

Could Return to Action Wednesday
Tim Hardaway Jr.

May Remain Out Wednesday
Christian Braun

Listed as Questionable for Wednesday
Aaron Gordon

Iffy for Wednesday
Jamal Murray

Considered Questionable for Wednesday Night
Max Strus

to Miss Another Month
Vince Williams Jr.

Making Return Tuesday Against Spurs
Trae Young

Listed as Questionable for Wednesday
New York Giants

John Harbaugh Expected to be Favorite to Become New Giants Head Coach
Mason Marchment

Out Tuesday
Sean Monahan

Available Tuesday
Jason Zucker

Set to Return From 11-Game Absence
Matvei Michkov

a Game-Time Call Tuesday
Matthew Schaefer

Cleared for Action Tuesday
Baltimore Ravens

John Harbaugh Won't Return as Ravens Head Coach
Adam Fox

Landing Back on Long-Term Injured Reserve
Seth Jarvis

Back for Hurricanes Tuesday
Bo Bichette

Unlikely to Return to Toronto?
Jordan Love

Ready to Start in Wild-Card Game Against Bears
CFB

Jadan Baugh Staying with Florida for Junior Season
Washington Commanders

Commanders "Mutually" Parting Ways With OC Kliff Kingsbury
CFB

Byrum Brown Officially Commits to Auburn
CFB

Austin Simmons Signing with Missouri
Jake McCabe

to Sit Out One Week
Hampus Lindholm

to Miss Time
Christian Dvorak

Flyers Sign Christian Dvorak to Five-Year Extension
Igor Shesterkin

Exits With Lower-Body Injury Monday
Joel Armia

Hurt in Monday's Win
Anze Kopitar

Sustains Lower-Body Injury Monday
Matthew Schaefer

a Game-Time Call Tuesday
CFB

Ty Simpson Undecided on 2026 Plans
CFB

Quarterback AJ Hill Following Ryan Silverfield to Arkansas
Atlanta Falcons

Falcons Have Requested an Interview With Klint Kubiak
Deshaun Watson

Browns Expect Deshaun Watson to be on the Team Next Year
Wan'Dale Robinson

Dealing With Fractured Ribs
Cam Skattebo

Hopes to be Back by Training Camp
Cameron Ward

Won't Need Surgery on his Shoulder
Davante Adams

Rams Expect Davante Adams to Return in Wild-Card Round
Arizona Cardinals

Cardinals Fire Head Coach Jonathan Gannon
Las Vegas Raiders

Raiders Fire Head Coach Pete Carroll
Malik Nabers

Unsure if He Will Be Ready for Week 1 of 2026 Season
CFB

Trinidad Chambliss Will Return to Ole Miss If Granted Sixth Year of Eligibility
Cincinnati Bengals

Zac Taylor Will Return as Bengals Head Coach in 2026
New York Giants

Giants Expected to Show Interest in Former Browns Head Coach Kevin Stefanski
Daniel Jones

Colts, Daniel Jones Appear to Have "Mutual Interest" in a 2026 Reunion
Cleveland Browns

Browns Fire Kevin Stefanski After Another Losing Season
Zay Flowers

Goes Off for 138 Yards, Two Touchdowns in Loss
Bo Bichette

Phillies Have Interest in Bo Bichette
Amon-Ra St. Brown

Dominates in Week 18 Win
Cameron Ward

Believed to Have Grade 3 AC Joint Sprain in Right Shoulder
Kansas City Royals

Matt Quatraro Signs Three-Year Extension With Royals
CFB

Transfer QB Billy Edwards Commits to North Carolina
CFB

Sam Leavitt Visiting Texas Tech on Saturday
CFB

DJ Lagway Expected To Visit Florida State
Kyle Tucker

Blue Jays "Remain the Favorite" to Sign Kyle Tucker
CFB

Joey Aguilar Undergoes Surgery to Remove Tumor on Friday
CFB

Texas the "Team to Beat" for Transfer Running Back Isaac Brown
CFB

Rocco Becht to Follow Matt Campbell to Penn State?
CFB

Texas Targeting Cam Coleman in Transfer Portal
CFB

Former Texas Running Back CJ Baxter Visiting Kentucky
CFB

Beau Pribula Visiting Virginia Tech, Georgia Tech
Bo Bichette

Yankees Showing Interest in Bo Bichette

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