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FantasyDraft Lineup Picks (Week 10) - NFL DFS Advice

It is finally time for NFL Week 10! If you're a FantasyDraft DFS player, then this article is for you.

Each week, I will be providing you with my daily fantasy football lineup picks for FantasyDraft. The lineup picks will range from some of the elite players to mid-priced options and value plays.

If you have any questions or comments, feel free to hit me up on Twitter @BalesSJustin.

 

FantasyDraft - DFS Quarterback Pick

Dak Prescott at ATL ($13,300)

Prescott has been playing at an elite level recently. He was not needed in a rainy game against the Redskins, but he has played well in each of his five games aside from that outlier. In those five games, Prescott is averaging 26.8 fantasy points per game. He gets a good matchup against Atlanta, who have been an average defense against the quarterback this season. This game is also expected to stay close, and Prescott can be used in all leagues.

 

FantasyDraft - DFS Running Back Picks

Le'Veon Bell at IND ($17,800)

Bell has been playing at an elite level this season. He's averaging 122.4 total yards and 0.6 touchdowns on 28.6 touches per game. He is the focal point of the Steelers offense, and he gets an elite matchup against the Indianapolis Colts, who have struggled against the run and pass this season. The Steelers are -10 point favorites in this game, suggesting they could run out the clock for the majority of the second half. Bell will see the majority of those touches, making him an elite option.

Lamar Miller at LAR ($9,500)

Miller has struggled at times this season, but he has recorded at least 15 touches in seven of his eight games this season. He gets an elite matchup against the Los Angeles Rams, who are allowing 121.6 rushing yards per game this season. They have also allowed eight rushing touchdowns. Miller is not an elite running back in the NFL, but he comes with a reasonable price tag, and he makes an elite tournament option this week.

 

FantasyDraft - DFS Wide Receiver Picks

Antonio Brown at IND ($17,900)

Brown has struggled with efficiency this season, as his catch rate and touchdown rate are lower than his career averages. Still, Brown is averaging a 7.1/103.4/0.4 line on 11.8 targets per game. The Colts have opted to cut Vontae Davis this week, meaning they will have a replacement level talent cornerback trying to keep up with Brown. He is an elite option in all leagues, even with the high price tag.

Demaryius Thomas vs NE ($10,700)

Thomas is an interesting option this week. The New England Patriots have been one of the worst defenses in the NFL this season. Thomas is one of the biggest beneficiaries of the Denver quarterback change, recording 12 targets in his only game with Brock Osweiler. He should be peppered with targets once again this week, making him a great option for his current price tag.

 

FantasyDraft - DFS Tight End Pick

Garrett Celek vs NYG ($5,000)

Celek is expected to draw the start for George Kittle this week. Last week, Celek saw four targets in limited playing time. He gets an elite matchup against the New York Giants, who rank 32nd in the NFL against the tight end. They have been allowing touchdowns to tight ends at an elite rate this season. Celek comes with an extremely low price tag, and he is an elite option in all leagues.

 

FantasyDraft - DFS Defense Pick

Chicago Bears D/ST vs GB ($5,100)

The Bears defense has quietly been playing extremely well this season. They are averaging 1.4 turnovers and 2.9 sacks per game this season. They have also scored three defensive touchdowns this season, as well. They get a great matchup against the Green Bay Packers, who have been struggling without Aaron Rodgers. The Bears are also -5.5 point favorites in a game set at only 38, giving Green Bay a low implied team total of 16.3 points. Chicago's defense could fly under the radar this week, but they can be used in all leagues.

 

More Week 10 DFS Analysis

 

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REAL-TIME FANTASY NEWS

Cameron Johnson

to Miss Time With Bone Bruise in Right Knee
Jaxson Hayes

Considered Questionable for Christmas Matchup
Rui Hachimura

Likely to Return Thursday
Dorian Finney-Smith

Could Make Season Debut on Christmas Day
Alperen Sengün

Alperen Sengun Uncertain for Christmas Day
Luka Dončić

Luka Doncic Listed as Questionable for Christmas Game
Al Horford

on Track to Return Thursday
Jaden McDaniels

Iffy for Christmas Day
Brandon Williams

Expected to Play on Christmas Day
P.J. Washington

at Risk of Missing Second Straight Game
Klay Thompson

Likely to Play on Christmas Day
Max Christie

Probable for Christmas Day
Ajay Mitchell

Out on Christmas Day
Chet Holmgren

Available on Christmas Day
Lonzo Ball

Available Against Knicks
Evan Mobley

Listed as Questionable for Christmas Tilt
OG Anunoby

Returns to Action Thursday
Jalen Brunson

Available on Christmas Day
David Montgomery

Questionable to Play With Illness
Amon-Ra St. Brown

Questionable, Expected to Play on Thursday
Rashee Rice

Chiefs Place Rashee Rice on Injured Reserve
T.J. Hockenson

Ruled Out for Week 17
Pete Fairbanks

Marlins Agree on One-Year Deal
Josh Johnson

to Start at QB on Thursday Against Dallas
Brooks Koepka

Leaving LIV Golf
Davante Adams

Could Sit Out Final Two Regular-Season Games
Brock Bowers

Placed on Injured Reserve Due to Lingering Knee Injury
Amon-Ra St. Brown

Expected to Play on Christmas Day Against the Vikings
Connor McDavid

Finishes Battle of Alberta With Five Assists
Karel Vejmelka

Battling Upper-Body Injury
Alexandre Texier

Suffers Upper-Body Injury Against Bruins
Alexander Nikishin

Dealing With Apparent Ankle Injury
Denver Barkey

Exits Early Tuesday
Travis Sanheim

Pulled by Concussion Spotter Tuesday
Cam Whitmore

Out Indefinitely With Deep Vein Thrombosis
Corey Kispert

Lasts for 13 Minutes in Comeback Game
Jaxson Hayes

Makes Early Exit Versus Suns
Ryan O'Hearn

Pirates Agree on Two-Year Deal
DK Metcalf

has Two-Game Suspension Upheld
Philip Rivers

to Remain the Starter in Week 17
George Kittle

Dealing With Mid-to-Low Ankle Sprain
Viktor Arvidsson

a Game-Time Decision Tuesday
Ryan Leonard

Available Tuesday
Tom Wilson

in Danger of Missing First Game of the Season
Phillip Danault

Makes Second Canadiens Debut Tuesday
Collin Graf

Available Against Golden Knights
Jack Eichel

Misses Fourth Straight Game
Vince Dunn

Won't Play Tuesday
Deshaun Watson

Will Not be Activated Off PUP List, 2025 Season is Over
J.J. McCarthy

Ruled Out for Week 17
Rome Odunze

Expected to Return This Season
Christian McCaffrey

Another Monster Game for Christian McCaffrey in Week 16
Brock Purdy

Throws for Five Touchdowns in Week 16
TreVeyon Henderson

in Concussion Protocol, Week 17 Status Unclear
George Kittle

Week 17 Availability in Question?
CFB

Jeff Brohm, Eli Drinkwitz "Names of Interest" for Michigan Head Coach
Timothy Liljegren

to Miss Second Straight Game Tuesday
Will Smith

Out Week-to-Week
Jaccob Slavin

Placed on Injured Reserve, Out Week-to-Week
Seth Jarvis

Considered Week-to-Week
Darren Raddysh

Totals Three Points in Monday's Win
Mason Marchment

Scores Twice Monday
Vince Dunn

Injured in Monday's Win
Rashee Rice

Still in Concussion Protocol, Estimated as Non-Participant on Monday
J.J. McCarthy

Listed as DNP on Monday Ahead of Week 17
Ilya Sorokin

to Miss Tuesday's Game
DK Metcalf

Suspended for Two Games Following Confrontation with Fan
CFB

Byrum Brown Entering Transfer Portal
CFB

Bobby Petrino Joining Bill Belichick as North Carolina's Offensive Coordinator
Willson Contreras

Shipped to the Red Sox
Brandon Lowe

Pirates Acquire Brandon Lowe in Three-Team Trade
Shane Baz

Orioles Acquire Shane Baz From the Rays
CFB

Darian Mensah Returning to Duke Next Season
CFB

Josh Hoover Linked to Indiana in Transfer Portal
CFB

Arch Manning Agrees to Reduced Compensation for 2026 Season

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