It is finally time for NFL Week 10! If you're a FantasyDraft DFS player, then this article is for you.

Each week, I will be providing you with my daily fantasy football lineup picks for FantasyDraft. The lineup picks will range from some of the elite players to mid-priced options and value plays.

If you have any questions or comments, feel free to hit me up on Twitter @BalesSJustin.

• 2025 fantasy football rankings
• Running back (RB) rankings
• Wide receiver (WR) rankings
• Quarterback (QB) rankings
• Tight end (TE) rankings
• Defense (D/ST) rankings
• Kicker (K) rankings
• FLEX rankings
• Dynasty rankings

FantasyDraft - DFS Quarterback Pick

Dak Prescott at ATL ($13,300)

Prescott has been playing at an elite level recently. He was not needed in a rainy game against the Redskins, but he has played well in each of his five games aside from that outlier. In those five games, Prescott is averaging 26.8 fantasy points per game. He gets a good matchup against Atlanta, who have been an average defense against the quarterback this season. This game is also expected to stay close, and Prescott can be used in all leagues.

FantasyDraft - DFS Running Back Picks

Le'Veon Bell at IND ($17,800)

Bell has been playing at an elite level this season. He's averaging 122.4 total yards and 0.6 touchdowns on 28.6 touches per game. He is the focal point of the Steelers offense, and he gets an elite matchup against the Indianapolis Colts, who have struggled against the run and pass this season. The Steelers are -10 point favorites in this game, suggesting they could run out the clock for the majority of the second half. Bell will see the majority of those touches, making him an elite option.

Lamar Miller at LAR ($9,500)

Miller has struggled at times this season, but he has recorded at least 15 touches in seven of his eight games this season. He gets an elite matchup against the Los Angeles Rams, who are allowing 121.6 rushing yards per game this season. They have also allowed eight rushing touchdowns. Miller is not an elite running back in the NFL, but he comes with a reasonable price tag, and he makes an elite tournament option this week.

FantasyDraft - DFS Wide Receiver Picks

Antonio Brown at IND ($17,900)

Brown has struggled with efficiency this season, as his catch rate and touchdown rate are lower than his career averages. Still, Brown is averaging a 7.1/103.4/0.4 line on 11.8 targets per game. The Colts have opted to cut Vontae Davis this week, meaning they will have a replacement level talent cornerback trying to keep up with Brown. He is an elite option in all leagues, even with the high price tag.

Demaryius Thomas vs NE ($10,700)

Thomas is an interesting option this week. The New England Patriots have been one of the worst defenses in the NFL this season. Thomas is one of the biggest beneficiaries of the Denver quarterback change, recording 12 targets in his only game with Brock Osweiler. He should be peppered with targets once again this week, making him a great option for his current price tag.

FantasyDraft - DFS Tight End Pick

Garrett Celek vs NYG ($5,000)

Celek is expected to draw the start for George Kittle this week. Last week, Celek saw four targets in limited playing time. He gets an elite matchup against the New York Giants, who rank 32nd in the NFL against the tight end. They have been allowing touchdowns to tight ends at an elite rate this season. Celek comes with an extremely low price tag, and he is an elite option in all leagues.

FantasyDraft - DFS Defense Pick

Chicago Bears D/ST vs GB ($5,100)

The Bears defense has quietly been playing extremely well this season. They are averaging 1.4 turnovers and 2.9 sacks per game this season. They have also scored three defensive touchdowns this season, as well. They get a great matchup against the Green Bay Packers, who have been struggling without Aaron Rodgers. The Bears are also -5.5 point favorites in a game set at only 38, giving Green Bay a low implied team total of 16.3 points. Chicago's defense could fly under the radar this week, but they can be used in all leagues.

More Week 10 DFS Analysis

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