Steelers vs Colts Start 'Em, Sit 'Em: Parris Campbell, Alec Pierce, Matt Ryan, Najee Harris, George Pickens, Diontae Johnson

Fantasy football start em, sit em and lineups advice for the Steelers vs Colts Monday Night game in Week 12 (2022). MNF matchups analysis with detailed breakdowns.

It's the final game of Week 12 fellow RotoBallers. We're here as always bringing you our Monday Night Football matchups analysis article for the Steelers vs. Colts. It's been yet another fun and crazy week of NFL and fantasy football action filled with big performances, new players emerging, and injuries. Hopefully, you're on the verge of winning your matchups (or already have).

Now we get one more game on Monday night to finish it off. Below you will find our matchups analysis for the Monday Night Football game between the Pittsburgh Steelers vs Indianapolis Colts. Hopefully, it will be an exciting game that adds to a week filled with plenty of booms, busts, and injuries.

Read our fantasy football breakdowns for these games -- the recommended starts, sits, and matchups we love heading into the Week 12 matchups. Good luck RotoBallers!

• 2025 fantasy football rankings
• Running back (RB) fantasy football rankings
• Wide receiver (WR) fantasy football rankings
• Tight end (TE) fantasy football rankings
• Quarterback (QB) fantasy football rankings
• FLEX fantasy football rankings
• Defense (D/ST) fantasy football rankings
• Kicker (K) fantasy football rankings
• Dynasty fantasy football rankings

Pittsburgh Steelers at Indianapolis Colts

Spread: Colts -2.5
Implied Total: Steelers (18.25) vs. Colts (20.75)
Pace: Steelers (12th) vs. Colts (10th)
Steelers Off. DVOA: 2.5% Pass (21st), -9.8% Rush (22nd)
Colts Off. DVOA: -21.5% Pass (31st), -24.3% Rush (32nd)
Steelers Def. DVOA: 9.1% Pass (19th), -14.4% Rush (7th)
Colts Def. DVOA: 2.8% Pass (14th), -17.0% Rush (6th)

Matchups We Love:

Pat Freiermuth (TE, PIT)

After leading the team with 12 targets, Freiermuth now has a 20.7% target share on the year, which is the sixth-highest among all tight ends. He also ranks seventh in yards per route run at the position with 1.76.

He's become an elite option, warranting top-10 consideration each week. The Colts have improved on defense since the coaching change to Jeff Saturday, but the matchup isn't bad enough to fade him.

Colts Wide Receivers

Michael Pittman Jr. and Parris Campbell continue to make an impact with Matt Ryan throwing them the ball. Alec Pierce actually led the team in targets, unfortunately, it only amounted to three catches for 28 yards.

The Steelers have been the best matchup for receivers over the course of the year, so even with T.J. Watt back, they're a favorable spot for Pittman Jr. and Campbell, who are both in the top 36. You could also take a shot a Pierce for a big play as a flex option.

Matchups We Hate:

Najee Harris (RB, PIT)

The two issues for Harris were his health and the involvement of Jaylen Warren. He appeared closer to the version of himself we saw last year on Sunday, plus Warren left with an injury.

Given that Warren has officially been ruled out, Harris will have a much larger workload. Indianapolis has been strong against the run, landing him right around that top-24 range.

Other Matchups:

Jonathan Taylor (RB, IND)

Taylor is another back who looks recovered and has performed well the past two weeks. Additionally, he's being utilized in the passing game, which adds to his value. He caught three passes on four targets.

It's another tougher matchup, but the Colts are favored, meaning it will at the very least stay competitive, enabling them to run the ball. Taylor is in the top 12.

George Pickens (WR, PIT)

Pickens showcased his big play ability racking up 83 yards and a score on four receptions. The six targets are still low, but his upside cannot be denied. He's a top-36 receiver that can give you a better day than many of the other players around him.

Diontae Johnson, who is supposed to be the No. 1 receiver, had fewer targets than Pickens and fewer yards than four other players. He's no longer a player you need to start, even as a flex option.

Injuries:

Jaylen Warren (hamstring)

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