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Fantasy Aces DFS Advice: Week 12 NFL - Daily Fantasy Football Picks

Hey there Rotoballers! In this article I will be taking a look at some of my favorite FantasyAces DFS lineups plays for the Week 12 slate.

These picks are based on a multitude of factors including matchup, talent, recent performance, and pricing on Fantasy Aces. Let's get to the picks!

Editor's Note: New users that sign up on FantasyAces, make a $20 deposit, and enter any game will receive BOTH our full season NFL and NBA Premium Passes for free, a $119.99 value. Just email [email protected] with your new FantasyAces username - and boom, that's it! We will email you with your Premium Passes.

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

Quarterback Plays for Fantasy Aces

Russell Wilson (@ TB, $6,800)

Based on his route running prowess last weekend, Wilson appears to be fully healthy following early season knee and ankle injuries which were clearly limiting his performance. Just like during the 2015 season, Wilson is heating up as we head into the stretch run of the season. Over his past three games, he has scored eight total touchdowns (including one rushing and one receiving). Look for Wilson's hot streak to continue this weekend when the Seahawks take on a beatable Tampa Bay secondary. The Bucs are allowing the sixth-most fantasy points per game to opposing signal callers. At just $6,800, Wilson has just as much upside as the most expensive quarterback options on the slate at a significant discount. 

 

Marcus Mariota (@ CHI, $6,250)

Mariota remains such a fantastic deal on Aces. His $6,250 price tag ranks him as just the 13th-most expensive quarterback on the site, even though he's been absolutely on fire over his past six games. In that span, Mariota has racked up 17 total touchdowns to go along with 1,684 yards. The Chicago defense hasn't been as bad as originally expected this season, but they still don't represent an imposing matchup by any stretch. On the year, Chicago's pass defense ranks 14th in DVOA according to Football Outsiders. As a second quarterback on Aces, Mariota offers plenty of upside at a reasonable price this weekend.

 

Running Back Plays for Fantasy Aces

Jay Ajayi (vs. SF, $5,500)

Ajayi is the latest running back to get a crack at the woeful San Francisco run defense. Ajayi has a perfect set of factors working in his favor in this matchup. The fast-paced 49ers offense ensures that the run-first Dolphins will run way more plays than usual. Football Outsiders has San Francisco's run defense ranked last in the league in DVOA. Add in the almost 29 fantasy points per game that San Francisco is allowing to running backs and Ajayi is the top running back play on the slate. Even better, he's over $1,000 cheaper than David Johnson, the highest priced back on the slate.   

 

Wendell Smallwood (vs. GB, $4,000)

Be sure to check in on Ryan Mathews' status before lineups lock on Sunday morning, but it's looking like Smallwood could be Philadelphia's lead back against the Packers on Monday night. Mathews sprained his MCL last week and has missed Wednesday and Thursday's practices so far. That makes Smallwood, at $4,000, a top value play at running back. While the Packers have solid season-long numbers against running backs, they have been getting gashed on the ground over the past couple of weeks. Last week, Robert Kelley smoked them for 137 yards and three touchdowns. Back in Week 10, the Packers coughed up 123 yards and a score to DeMarco Murray

 

Wide Receiver Plays for Fantasy Aces

Amari Cooper (vs. CAR, $5,200)

Cooper shapes up as one of the top receivers on the slate as he draws a plum matchup against a very burnable Carolina secondary. With the Panthers sporting a stout run defense, expect the Raiders to take to the air early and often in Oakland. Cooper has either 100 yards or a score in four of his past six games and should have no trouble getting open against the Panthers. Carolina's pass defense, according to Football Outsiders, is 27th in DVOA against opposing number one wide receivers. 

 

Larry Fitzgerald (@ ATL, $4,900)

Fitzgerald just keeps on producing, catching six passes or more passes in all but one game this season while seeing double-digit targets in 6-of-10 games played. In the latter stages of his career he runs most of his routes from the slot, meaning he will avoid the coverage of Desmond Trufant, Atlanta's shutdown cornerback. Instead of Trufant, Fitzgerald will get to pick on rookie slot corner Brian Poole. You have to like the chances for Fitzgerald in that matchup. 

 

Tight End Play for Fantasy Aces

Cameron Brate (vs. SEA, $4,200)

Cameron Brate could be in for a big afternoon as the Buccaneers could be forced to lean on him in the passing game. Tampa Bay's top receiver and resident target hog, Mike Evans, is expected to draw shadow coverage from lockdown corner Richard Sherman. With that being the case, expect Jameis Winston to funnel extra looks towards Brate. Brate has scored a touchdown in three of the past four games and has a good shot at scoring again against Seattle. As good as the Seahawks' defense is, they have had their struggles against tight ends over the past few years. 

 

Defense/Special Teams Play for Fantasy Aces

Buffalo Bills (vs. JAX, $2,900)

The Bills have a favorable home matchup against the turnover-prone Jaguars. They head into Sunday's game as -7.5 favorites in a game that should be low-scoring, with the over/under set at 44.5 points. Jacksonville quarterback Blake Bortles has taken a huge step back this season and is tied for first in the league with 13 interceptions. Buffalo's defense ranks first in the league with 31 sacks. A fearsome pass rush taking on an interception-prone quarterback is usually a recipe for fantasy success.




REAL-TIME FANTASY NEWS

Rasmus Hojgaard

Looking to Shake Off Poor Major Showing at TPC Craig Ranch
Joel Dahmen

is of No DFS Consideration This Week in Dallas
Pierceson Coody

is Not The Fun DFS Play He Used to Be
Tank Bigsby

Is Tank Bigsby a Worthy Dynasty Stash Entering 2026?
Hunter Henry

Profiles as a Dynasty Sell-High Candidate Entering 2026
Gerrit Cole

to Make Season Debut on Friday Against Rays
Matthew Golden

Can Matthew Golden Re-Establish His Dynasty Value in 2026?
Jalen Coker

a Prime Buy-Low Dynasty Target
Dak Prescott

Remains a High-Floor Dynasty Quarterback
CeeDee Lamb

Is CeeDee Lamb's Dynasty Value Poised to Rise in 2026?
Keon Coleman

Joe Brady Likes What he's Seen From Keon Coleman
Deshaun Watson

Hitting it Off With Todd Monken?
Jacoby Brissett

Not Present for First OTA Practice
Tua Tagovailoa

Michael Penix Jr. Splitting First-Team Reps at OTAs
Rashee Rice

Tests Positive for Marijuana, Violating his Probation
Cam Skattebo

Says he'll be Ready for Week 1
De'Von Achane

Present for Start of OTAs This Week
Malik Washington

an Affordable Trade Target in Dynasty Leagues
Patrick Mahomes

Is Patrick Mahomes Still a Top-Five Dynasty Quarterback?
Michael Trigg

Is There a Spot for Michael Trigg in Dallas?
Seth McGowan

in the Mix for Playing Time as a Rookie?
Audric Estimé

Audric Estime Droppable in Dynasty Leagues?
Drake Baldwin

Braves Place Drake Baldwin on Injured List With Oblique Strain
Kyren Williams

Have Timeshare Concerns Sunk Kyren Williams' Dynasty Value Too Low?
Ja'Marr Chase

Is Ja'Marr Chase the Most Valuable Player in Dynasty?
Javonte Williams

' Unusual Career Path Has Left Him Undervalued in Dynasty Leagues
CFB

Ezavier Crowell has Immediate Opportunity at Alabama
CFB

Mark Bowman a Day 1 Impact Player for USC?
CFB

Bill Belichick Says Relationship with First North Carolina Team "Wasn't Great"
Alex Caruso

Erupts for 31 Points in Game 1 Loss to Spurs
CFB

Kemario Taylor a Breakout Candidate at Quarterback
Jalen Williams

Productive in Comeback Game
CFB

Trinidad Chambliss the Undisputed Top SEC Quarterback Entering 2026?
Shai Gilgeous-Alexander

Records First Double-Double of Postseason
CFB

Rocco Becht The "Unifier" of Penn State's Roster
Stephon Castle

Opens Conference Finals With Double-Double
Dylan Harper

Makes Outstanding Two-Way Impact in Game 1 Win
Victor Wembanyama

Dominates Game 1 Against Thunder
Mattias Samuelsson

Picks Up an Assist in Season-Ending Loss
Rasmus Dahlin

Nets Fourth Postseason Goal
Jakub Dobes

Records 37 Saves in Game 7 Win
Lane Hutson

Contributes Power-Play Assist in Game 7 Victory
Nick Suzuki

Extends Road Point Streak
Alex Newhook

Scores Series-Clincher in Overtime
Jackson Holliday

Orioles Reinstate Jackson Holliday From Injured List on Monday
Ronald Acuña Jr.

Braves Reinstate Ronald Acuna Jr. From Injured List on Monday
Jose Altuve

Astros Put Jose Altuve on Injured List With Oblique Strain
Larry Nance Jr.

is Questionable for Game 1 on Tuesday
OG Anunoby

is Probable for Tuesday's Game 1
Luke Kornet

is Cleared for Game 1
New Orleans Pelicans

Jamahl Mosley Agrees to Become Pelicans Next Head Coach
De'Aaron Fox

is Ruled Out for Game 1 on Monday
Ukko-Pekka Luukkonen

Set to Start Game 7
Corey Seager

Going on Injured List With Back Injury
Tage Thompson

Can Match Franchise Record With Another Multi-Point Game
Nick Suzuki

Seeks More Road Success Monday
Lane Hutson

Riding a Five-Game Assist Streak Into Game 7
Filip Gustavsson

Needs Offseason Surgery
Jeremy Peña

Jeremy Pena Reinstated and Starting on Monday Against Twins
Melquizael Costa

Drops Decision At UFC Vegas 117
Arnold Allen

Bounces Back
Daniel Santos

Suffers Second-Round TKO Loss
MMA

Dohoo Choi Wins His Third Consecutive Fight
Malcolm Wellmaker

Suffers His Second Loss In A Row
Juan Diaz

Scores Second-Round Submission
Christian Edwards

Defeated At UFC Vegas 117
CFB

Transfer Running Back Arnold Barnes Visiting Iowa State on Monday
Modestas Bukauskas

Gets Split-Decision Win
Jhostynxon Garcia

Expected to Join the Pirates on Tuesday
Tobias Harris

Goes Cold in Game 7 Loss
Quinn Hughes

Open to Signing Extension This Offseason
Jalen Duren

Finishes Game 7 with Quiet Line
Cade Cunningham

Endures Cold Shooting Night Sunday
Joel Eriksson Ek

Misses Second Round Due to Heel Injury
Sam Merrill

Catches Fire in Game 7 Win
Evan Mobley

Posts Versatile Double-Double in Game 7
Jonas Brodin

Sits Out Round 2 Due to Toe Injury
Donovan Mitchell

Guides Cavaliers Into East Finals
Sam Malinski

Practices Fully Sunday
Jarrett Allen

Scores 23 Points in Cavs' Game 7 Rout of Pistons
Josh Manson

Rejoins Practice
Kevin Huerter

Active on Sunday Night
Caris LeVert

Duncan Robinson, Caris LeVert Available Sunday
Dean Wade

Max Strus Replaces Dean Wade in Starting Lineup Sunday
Colt Emerson

Mariners Promoting Top Prospect Colt Emerson to Major Leagues
Munetaka Murakami

Fantastic First Season Continues With Two More Homers
Cristopher Sánchez

Cristopher Sanchez Dazzles With 13-Strikeout Complete Game on Saturday
Blake Snell

to Undergo Elbow Surgery on Tuesday
Clay Holmes

Could Miss Around Three Months
Jose Altuve

Exits After Swing
Corey Seager

Absent With Back Spasms on Saturday
Jeremy Lauzon

Misses Saturday's Practice
Mark Stone

Doesn't Practice Saturday
Josh Manson

Misses Practice, Considered Day-to-Day
Brent Burns

Day-to-Day Ahead of Conference Finals
Cale Makar

Considered Day-to-Day
Trevor Story

Hits the Injured List With Groin Injury
Blake Snell

Likely to Need Elbow Surgery
Kyle Schwarber

on a Heater, Hits Two More Homers to Take Major-League Lead
Clay Holmes

Suffers Fractured Fibula on Friday Night
Blake Snell

Heads to 15-Day Injured List
Blake Snell

Scratched From Start on Friday for Undisclosed Reasons
CFB

Julian Sayin Looking To Build Off Of Strong Debut Season
CFB

College GameDay Set for First Three Weeks
CFB

Jeremiah Smith Aiming For Ohio State Receiving Records
CFB

Keshaun Singleton Projects as Auburn's WR1
CFB

Jeremiah Cobb Impresses New Auburn Staff
CFB

Alberto Mendoza Very Likely to Start for Georgia Tech
CFB

Charles Woodson Jr. Commits to Michigan
Melquizael Costa

Set For UFC Vegas 117 Main Event
Arnold Allen

A Favorite At UFC Vegas 117
Daniel Santos

Set For UFC Vegas 117 Co-Main Event
MMA

Dohoo Choi Returns At UFC Vegas 117
Juan Diaz

Set To Make His UFC Debut
Malcolm Wellmaker

Looks To Bounce Back
Christian Edwards

Set For His UFC Debut
Modestas Bukauskas

Looks To Get Back In The Win Column
CFB

Virginia Tech Lands Commitment from Four-Star QB Peter Bourque
RANKINGS
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1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF