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Fantasy Aces DFS Advice: Week 12 NFL - Daily Fantasy Football Picks

Hey there Rotoballers! In this article I will be taking a look at some of my favorite FantasyAces DFS lineups plays for the Week 12 slate.

These picks are based on a multitude of factors including matchup, talent, recent performance, and pricing on Fantasy Aces. Let's get to the picks!

Editor's Note: New users that sign up on FantasyAces, make a $20 deposit, and enter any game will receive BOTH our full season NFL and NBA Premium Passes for free, a $119.99 value. Just email [email protected] with your new FantasyAces username - and boom, that's it! We will email you with your Premium Passes.

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

Quarterback Plays for Fantasy Aces

Russell Wilson (@ TB, $6,800)

Based on his route running prowess last weekend, Wilson appears to be fully healthy following early season knee and ankle injuries which were clearly limiting his performance. Just like during the 2015 season, Wilson is heating up as we head into the stretch run of the season. Over his past three games, he has scored eight total touchdowns (including one rushing and one receiving). Look for Wilson's hot streak to continue this weekend when the Seahawks take on a beatable Tampa Bay secondary. The Bucs are allowing the sixth-most fantasy points per game to opposing signal callers. At just $6,800, Wilson has just as much upside as the most expensive quarterback options on the slate at a significant discount. 

 

Marcus Mariota (@ CHI, $6,250)

Mariota remains such a fantastic deal on Aces. His $6,250 price tag ranks him as just the 13th-most expensive quarterback on the site, even though he's been absolutely on fire over his past six games. In that span, Mariota has racked up 17 total touchdowns to go along with 1,684 yards. The Chicago defense hasn't been as bad as originally expected this season, but they still don't represent an imposing matchup by any stretch. On the year, Chicago's pass defense ranks 14th in DVOA according to Football Outsiders. As a second quarterback on Aces, Mariota offers plenty of upside at a reasonable price this weekend.

 

Running Back Plays for Fantasy Aces

Jay Ajayi (vs. SF, $5,500)

Ajayi is the latest running back to get a crack at the woeful San Francisco run defense. Ajayi has a perfect set of factors working in his favor in this matchup. The fast-paced 49ers offense ensures that the run-first Dolphins will run way more plays than usual. Football Outsiders has San Francisco's run defense ranked last in the league in DVOA. Add in the almost 29 fantasy points per game that San Francisco is allowing to running backs and Ajayi is the top running back play on the slate. Even better, he's over $1,000 cheaper than David Johnson, the highest priced back on the slate.   

 

Wendell Smallwood (vs. GB, $4,000)

Be sure to check in on Ryan Mathews' status before lineups lock on Sunday morning, but it's looking like Smallwood could be Philadelphia's lead back against the Packers on Monday night. Mathews sprained his MCL last week and has missed Wednesday and Thursday's practices so far. That makes Smallwood, at $4,000, a top value play at running back. While the Packers have solid season-long numbers against running backs, they have been getting gashed on the ground over the past couple of weeks. Last week, Robert Kelley smoked them for 137 yards and three touchdowns. Back in Week 10, the Packers coughed up 123 yards and a score to DeMarco Murray

 

Wide Receiver Plays for Fantasy Aces

Amari Cooper (vs. CAR, $5,200)

Cooper shapes up as one of the top receivers on the slate as he draws a plum matchup against a very burnable Carolina secondary. With the Panthers sporting a stout run defense, expect the Raiders to take to the air early and often in Oakland. Cooper has either 100 yards or a score in four of his past six games and should have no trouble getting open against the Panthers. Carolina's pass defense, according to Football Outsiders, is 27th in DVOA against opposing number one wide receivers. 

 

Larry Fitzgerald (@ ATL, $4,900)

Fitzgerald just keeps on producing, catching six passes or more passes in all but one game this season while seeing double-digit targets in 6-of-10 games played. In the latter stages of his career he runs most of his routes from the slot, meaning he will avoid the coverage of Desmond Trufant, Atlanta's shutdown cornerback. Instead of Trufant, Fitzgerald will get to pick on rookie slot corner Brian Poole. You have to like the chances for Fitzgerald in that matchup. 

 

Tight End Play for Fantasy Aces

Cameron Brate (vs. SEA, $4,200)

Cameron Brate could be in for a big afternoon as the Buccaneers could be forced to lean on him in the passing game. Tampa Bay's top receiver and resident target hog, Mike Evans, is expected to draw shadow coverage from lockdown corner Richard Sherman. With that being the case, expect Jameis Winston to funnel extra looks towards Brate. Brate has scored a touchdown in three of the past four games and has a good shot at scoring again against Seattle. As good as the Seahawks' defense is, they have had their struggles against tight ends over the past few years. 

 

Defense/Special Teams Play for Fantasy Aces

Buffalo Bills (vs. JAX, $2,900)

The Bills have a favorable home matchup against the turnover-prone Jaguars. They head into Sunday's game as -7.5 favorites in a game that should be low-scoring, with the over/under set at 44.5 points. Jacksonville quarterback Blake Bortles has taken a huge step back this season and is tied for first in the league with 13 interceptions. Buffalo's defense ranks first in the league with 31 sacks. A fearsome pass rush taking on an interception-prone quarterback is usually a recipe for fantasy success.




REAL-TIME FANTASY NEWS

Parker Washington

Set to Play "Most Important Role" of His Career in Jaguars Offense
Elly De La Cruz

Exits with Hamstring Tightness
Tyler Reddick

Is One of the Top Favorites to Win at Nashville
Kyle Larson

May Continue his Top-10 Consistency at Nashville this week
Christopher Bell

Is One of the Top Competitors for the Win at Nashville
Chase Briscoe

Is A Must Start for Nashville DFS Lineups
Chase Elliott

has Plenty of Upside for Nashville DFS Lineups
William Byron

Is William Byron A Playable DFS Option for Nashville Lineups?
Wan'Dale Robinson

Dynasty Value May Have Peaked in 2025
Carson Hocevar

Is Likely to have Another Solid Result at Nashville
Tyler Shough

Should Dynasty Managers Consider Selling High on Tyler Shough?
NASCAR

Should Fantasy Players Roster Bubba Wallace at Nashville?
Garrett Wilson

Dynasty Upside Remains High Despite Questionable Offensive Environment in New York
Chris Buescher

Is A Decent All-Around DFS Option for Nashville Lineups
Daniel Suarez

is Likely to Drop Positions during the Cracker Barrel 400
Kenneth Gainwell

Carries Dynasty Sell-High Appeal After Breakout 2025 Campaign
Emeka Egbuka

Undervalued in Dynasty Formats After Underwhelming Close to 2025?
Trey Benson

a Dynasty Hold Despite Unfavorable Situation
Omar Cooper Jr.

a Long-Term Investment in the First Round of Rookie Drafts
Colston Loveland

Just How High is Colston Loveland's Dynasty Ceiling?
Garrett Crochet

Suffers Setback, Likely to Undergo MRI for Lat Tightness
Zay Flowers

A New-Look Offense in Baltimore Could Impact Zay Flowers' Dynasty Value
LeQuint Allen Jr.

a Dynasty Dart Throw with a Potential Path to Upside
Denny Hamlin

Could Denny Hamlin Dominate at Nashville?
Ryan Blaney

Is a DFS Tournament Option at Nashville
Ty Gibbs

Don't Overlook Ty Gibbs at Nashville
Joey Logano

Could Show Life at Nashville
Ross Chastain

Needs a Good Run at Nashville
Shedeur Sanders

Falling Behind in Quarterback Competition?
Isaiah Davis

Is Isaiah Davis the More Valuable Jets Handcuff?
Trey McBride

a Coveted Dynasty Cornerstone
Chet Holmgren

Fails to Step Up in the Season Finale
Brock Purdy

Still Not Valued as a Dynasty QB1
Cason Wallace

Ends Postseason with Strong Showing
Shai Gilgeous-Alexander

Caps MVP Season with Game 7 Exit
Justin Jefferson

an Obvious Bounce-Back Candidate
Stephon Castle

Continues Postseason Run with 16 Points
Julian Champagnie

Shines in Series-Clinching Win
De'Aaron Fox

Provides Secondary Punch in Game 7 Triumph
Victor Wembanyama

Earns Conference Finals MVP in Spurs' Game 7 Win
J.J. McCarthy

Holding J.J. McCarthy in Dynasty Leagues Will Require Patience
Harold Fannin Jr.

Does Harold Fannin Jr. Have Top-Three Upside in Dynasty Leagues?
Jaylen Waddle

the Top Receiver to Roster in Denver?
Josh Downs

Climbing Up the Dynasty Rankings with Bigger Role Ahead?
Jalen McMillan

Has Been 'Slightly Better' Than Teammate During OTAs
NBA

Warriors Prioritize Depth Around Returning Steve Kerr
Donovan Mitchell

Remains Cleveland's Top Priority
Adou Thiero

Remains a Lakers Development Project
NBA

76ers Hire Mike Gansey as President of Basketball Operations
NBA

Chicago Bulls Explore Kevin Young as Coaching Candidate
Kyrie Irving

Reports He's Nearing Full Strength in ACL Recovery
Lane Hutson

Posts a Power-Play Assist in Game 5 Loss
Cole Caufield

Nets a Power-Play Goal in Season-Ending Loss
Seth Jarvis

Closes Out East Finals With Multi-Point Game
Logan Stankoven

Notches Three Points in Big Game 5 Win
Taylor Hall

Racks Up Three Points in Series-Clinching Win
Frederik Andersen

Remains Stellar as Hurricanes Clinch Finals Berth
Jacob Gonzalez

is Heading to the Big Leagues
Munetaka Murakami

Exits with Hamstring Tightness
Mitchell Robinson

Plans to Play in Game 1 After Finger Surgery
Ajay Mitchell

Ruled Out for Game 7
Jalen Williams

Unavailable in Decisive Game 7
NBA

Magic Finalizing Hire of Sean Sweeney as Head Coach
Eury Pérez

Eury Perez is Placed on 15-Day Injured List
Deiveson Figueiredo

Set For UFC Macau Main Event
MMA

Yadong Song Returns At UFC Macau
Alonzo Menifield

An Underdog At UFC Macau
Zhang Mingyang

Set For UFC Macau Co-Main Event
Tallison Teixeira

Looks To Win Back-To-Back Fights
Sergei Pavlovich

A Favorite At UFC Macau
Cameron Smotherman

Looks To Bounce Back
Kai Asakura

Looks To Get Back In The Win Column
CFB

Faizon Brandon In Position to Start Week 1
CFB

Dane Weber Commits to Cal
CFB

Joey McGuire Attempts to Add Texas to Schedule
CFB

Mike Leach on 2027 College Football Hall of Fame Ballot
CFB

Maryland, Baylor Schedule Home-and-Home
CFB

Taron Dickens Decommits From North Carolina
Jalen Williams

Limited in Game 6 Return
Jared McCain

Provides Bench Spark in Game 6 Loss
Shai Gilgeous-Alexander

Posts Lowest-Scoring Night of His MVP Season
De'Aaron Fox

Struggles From the Field Thursday
MLB

MLB Proposes Hard Salary Cap as Part of Next CBA
Kenley Jansen

Tigers Place Kenley Jansen on Injured List With Pelvic Inflammation
Teoscar Hernández

Teoscar Hernandez Heading to Injured List With Hamstring Strain
MON

Lane Hutson Struggles in Game 4 Loss
CAR

Logan Stankoven Nets Eighth Postseason Goal
CAR

Sebastian Aho Pots Game-Winner on Power Play
CAR

Nikolaj Ehlers Tallies Two Helpers in Impressive Road Win
CAR

Shayne Gostisbehere Records Two Assists in Game 4 Win
CAR

Frederik Andersen Establishes Hurricanes New Postseason Shutout Record
Yordan Alvarez

Continues Homer Barrage With Two More Long Balls on Wednesday
Cristopher Sánchez

Cristopher Sanchez Makes History With Seven More Shutout Innings Against Padres
Teoscar Hernández

Teoscar Hernandez Lifted From Wednesday's Game Early With Hamstring Strain
Kenley Jansen

Exits Relief Appearance on Wednesday With Groin Injury
Eury Pérez

Eury Perez Pulled Early on Wednesday With Hamstring Issue
CFB

Drew Mestemaker a Top Big 12 Quarterback Right Away?
PGA

Sungjae Im Remains Boom-or-Bust at Colonial
PGA

Michael Thorbjornsen Trending in Wrong Direction Entering Colonial
Russell Henley

a Top Option at Colonial
Harry Hall

Hoping Putter Carries Him at Colonial
Rickie Fowler

Looks to Regain Momentum at Colonial
Pierceson Coody

Looking to Stay Hot at Colonial
Martin Necas

Collects an Assist in Game 4 Loss to Golden Knights
Gabriel Landeskog

Scores Only Avalanche Goal in Season-Ending Loss
Carter Hart

Finishes Series-Clincher With 20 Saves
Dylan Coghlan

Continues Unlikely Success Story
Cole Smith

Scores Series-Clincher Tuesday Night
Mark Stone

Nets Another Goal as Golden Knights Finish Off Avalanche
Ludvig Aberg

Looking to Exchange Momentum for a Victory in Fort Worth
Stephan Jaeger

Trending Upward as PGA Heads to Fort Worth
Max Homa

Comes Off Awful Putting Performance at PGA Championship
Tony Finau

Faces Different Test at the Colonial
Robert MacIntyre

Seeks Better Beginning in Fort Worth
Tom Hoge

Ups and Downs Could Continue at Colonial
Brian Harman

Not Having the Best Golf Season in 2026
Austin Eckroat

Struggling Too Often Heading to Charles Schwab Challenge
Zach Bauchou

Tries to Keep Momentum Rolling at Colonial
Keegan Bradley

Looking to Rebound at Colonial
Claude Giroux

Planning to Return for 20th NHL Campaign
Carter Hart

Aiming for Sixth Consecutive Win Tuesday
Evgeni Malkin

Inks New One-Year Deal With Penguins
Ben Griffin

Looking to Repeat This Week at Colonial
Rasmus Hojgaard

a Player to Avoid at Charles Schwab Challenge
Hideki Matsuyama

Needs Solid Driving Week at Charles Schwab Challenge
Justin Thomas

Trending Well Ahead of Charles Schwab Challenge
Akshay Bhatia

Lacking Driving Prowess Needed at Colonial Country Club
CFB

DJ Lagway Looking to Rebound at Baylor
CFB

Josh Hoover Tasked With Leading Indiana Back to the Playoffs
CFB

Braylon Staley the Next 1,000-Yard Tennessee Receiver?
CFB

Ahmad Hardy's Return Timeline Remains Unclear
Gage Jump

Athletics to Promote Top Pitching Prospect Gage Jump to Major Leagues
Tatsuya Imai

Two Relievers Combine to No-Hit the Rangers on Monday
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF