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Fantasy Aces DFS Advice: Week 12 NFL - Daily Fantasy Football Picks

Hey there Rotoballers! In this article I will be taking a look at some of my favorite FantasyAces DFS lineups plays for the Week 12 slate.

These picks are based on a multitude of factors including matchup, talent, recent performance, and pricing on Fantasy Aces. Let's get to the picks!

Editor's Note: New users that sign up on FantasyAces, make a $20 deposit, and enter any game will receive BOTH our full season NFL and NBA Premium Passes for free, a $119.99 value. Just email [email protected] with your new FantasyAces username - and boom, that's it! We will email you with your Premium Passes.

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

Quarterback Plays for Fantasy Aces

Russell Wilson (@ TB, $6,800)

Based on his route running prowess last weekend, Wilson appears to be fully healthy following early season knee and ankle injuries which were clearly limiting his performance. Just like during the 2015 season, Wilson is heating up as we head into the stretch run of the season. Over his past three games, he has scored eight total touchdowns (including one rushing and one receiving). Look for Wilson's hot streak to continue this weekend when the Seahawks take on a beatable Tampa Bay secondary. The Bucs are allowing the sixth-most fantasy points per game to opposing signal callers. At just $6,800, Wilson has just as much upside as the most expensive quarterback options on the slate at a significant discount. 

 

Marcus Mariota (@ CHI, $6,250)

Mariota remains such a fantastic deal on Aces. His $6,250 price tag ranks him as just the 13th-most expensive quarterback on the site, even though he's been absolutely on fire over his past six games. In that span, Mariota has racked up 17 total touchdowns to go along with 1,684 yards. The Chicago defense hasn't been as bad as originally expected this season, but they still don't represent an imposing matchup by any stretch. On the year, Chicago's pass defense ranks 14th in DVOA according to Football Outsiders. As a second quarterback on Aces, Mariota offers plenty of upside at a reasonable price this weekend.

 

Running Back Plays for Fantasy Aces

Jay Ajayi (vs. SF, $5,500)

Ajayi is the latest running back to get a crack at the woeful San Francisco run defense. Ajayi has a perfect set of factors working in his favor in this matchup. The fast-paced 49ers offense ensures that the run-first Dolphins will run way more plays than usual. Football Outsiders has San Francisco's run defense ranked last in the league in DVOA. Add in the almost 29 fantasy points per game that San Francisco is allowing to running backs and Ajayi is the top running back play on the slate. Even better, he's over $1,000 cheaper than David Johnson, the highest priced back on the slate.   

 

Wendell Smallwood (vs. GB, $4,000)

Be sure to check in on Ryan Mathews' status before lineups lock on Sunday morning, but it's looking like Smallwood could be Philadelphia's lead back against the Packers on Monday night. Mathews sprained his MCL last week and has missed Wednesday and Thursday's practices so far. That makes Smallwood, at $4,000, a top value play at running back. While the Packers have solid season-long numbers against running backs, they have been getting gashed on the ground over the past couple of weeks. Last week, Robert Kelley smoked them for 137 yards and three touchdowns. Back in Week 10, the Packers coughed up 123 yards and a score to DeMarco Murray

 

Wide Receiver Plays for Fantasy Aces

Amari Cooper (vs. CAR, $5,200)

Cooper shapes up as one of the top receivers on the slate as he draws a plum matchup against a very burnable Carolina secondary. With the Panthers sporting a stout run defense, expect the Raiders to take to the air early and often in Oakland. Cooper has either 100 yards or a score in four of his past six games and should have no trouble getting open against the Panthers. Carolina's pass defense, according to Football Outsiders, is 27th in DVOA against opposing number one wide receivers. 

 

Larry Fitzgerald (@ ATL, $4,900)

Fitzgerald just keeps on producing, catching six passes or more passes in all but one game this season while seeing double-digit targets in 6-of-10 games played. In the latter stages of his career he runs most of his routes from the slot, meaning he will avoid the coverage of Desmond Trufant, Atlanta's shutdown cornerback. Instead of Trufant, Fitzgerald will get to pick on rookie slot corner Brian Poole. You have to like the chances for Fitzgerald in that matchup. 

 

Tight End Play for Fantasy Aces

Cameron Brate (vs. SEA, $4,200)

Cameron Brate could be in for a big afternoon as the Buccaneers could be forced to lean on him in the passing game. Tampa Bay's top receiver and resident target hog, Mike Evans, is expected to draw shadow coverage from lockdown corner Richard Sherman. With that being the case, expect Jameis Winston to funnel extra looks towards Brate. Brate has scored a touchdown in three of the past four games and has a good shot at scoring again against Seattle. As good as the Seahawks' defense is, they have had their struggles against tight ends over the past few years. 

 

Defense/Special Teams Play for Fantasy Aces

Buffalo Bills (vs. JAX, $2,900)

The Bills have a favorable home matchup against the turnover-prone Jaguars. They head into Sunday's game as -7.5 favorites in a game that should be low-scoring, with the over/under set at 44.5 points. Jacksonville quarterback Blake Bortles has taken a huge step back this season and is tied for first in the league with 13 interceptions. Buffalo's defense ranks first in the league with 31 sacks. A fearsome pass rush taking on an interception-prone quarterback is usually a recipe for fantasy success.




REAL-TIME FANTASY NEWS

Jacory Croskey-Merritt

Held Out of OTAs on Wednesday
Jayden Daniels

Participating in Commanders OTAs
Chris Bell

No Timetable for Chris Bell's Return from Knee Surgery
De'Von Achane

Limited in OTAs Due to Recovery From Shoulder Injury
MarShawn Lloyd

Participating in Packers OTAs
Josh Jacobs

No Criminal Charges Filed Against Josh Jacobs
Eury Pérez

Eury Perez Pulled Early on Wednesday With Hamstring Issue
Daniel Jones

Present at OTA Practice on Wednesday
CFB

Drew Mestemaker a Top Big 12 Quarterback Right Away?
T.J. Hockenson

Dynasty Stock Continues to Trend Down
Jordan Addison

Is Jordan Addison a Clear Buy-Low Candidate Ahead of 2026?
Cade Otton

Continues to Offer Depth in Dynasty Leagues
PGA

Sungjae Im Remains Boom-or-Bust at Colonial
Jared Goff

Continues to Have Dynasty Appeal at 31 Years Old
Tez Johnson

No Clear Path to Fantasy Relevance for Tez Johnson in Tampa Bay?
PGA

Michael Thorbjornsen Trending in Wrong Direction Entering Colonial
Zach Ertz

Could Still Contribute in Dynasty Leagues
De'Aaron Fox

Limited to Nine Points in Game 5 Loss
Russell Henley

a Top Option at Colonial
Dyami Brown

Holds Little Dynasty Value in His Return to Washington
Harry Hall

Hoping Putter Carries Him at Colonial
Julian Champagnie

Notches 22 Points With Four Triples Tuesday
Trevor Etienne

Could Still Find Dynasty Relevance After Quiet Rookie Season
Stephon Castle

Leads Spurs in Scoring Tuesday Night
Rickie Fowler

Looks to Regain Momentum at Colonial
Victor Wembanyama

Struggles in Game 5 Loss to Thunder
Bam Knight

Dynasty Value Has Run Dry in Crowded Running Back Room
Alex Caruso

a Difference-Maker Again in Game 5
Pierceson Coody

Looking to Stay Hot at Colonial
Jared McCain

Produces 20 Points in First Playoff Start
Mac Jones

and 49ers Agree to a Revised Contract
Shai Gilgeous-Alexander

Scores Game-High 32 Points in Game 5 Win
Martin Necas

Collects an Assist in Game 4 Loss to Golden Knights
Gabriel Landeskog

Scores Only Avalanche Goal in Season-Ending Loss
Carter Hart

Finishes Series-Clincher With 20 Saves
Dylan Coghlan

Continues Unlikely Success Story
Cole Smith

Scores Series-Clincher Tuesday Night
Mark Stone

Nets Another Goal as Golden Knights Finish Off Avalanche
Ludvig Aberg

Looking to Exchange Momentum for a Victory in Fort Worth
Stephan Jaeger

Trending Upward as PGA Heads to Fort Worth
Max Homa

Comes Off Awful Putting Performance at PGA Championship
Tony Finau

Faces Different Test at the Colonial
Robert MacIntyre

Seeks Better Beginning in Fort Worth
Tom Hoge

Ups and Downs Could Continue at Colonial
Brian Harman

Not Having the Best Golf Season in 2026
Austin Eckroat

Struggling Too Often Heading to Charles Schwab Challenge
Zach Bauchou

Tries to Keep Momentum Rolling at Colonial
Keegan Bradley

Looking to Rebound at Colonial
Tory Horton

Could Do Some Stuff "Toward the End of Spring"
Patrick Mahomes

Takes Part in First OTA Practice on Tuesday
Los Angeles Chargers

Derwin James Jr. Becomes Highest-Paid Safety for the Second Time in his Career
Chris Brooks

Emerging as Top Handcuff to Stash?
Jared McCain

Moves into Starting Five
Boston Celtics

Joe Mazzulla Wins Coach of the Year
Jalen Williams

is Ruled Out for Game 5 on Tuesday
Zion Williamson

to See More Versatile Role
Cleveland Cavaliers

Kenny Atkinson to Remain Cavaliers Head Coach Next Season
Claude Giroux

Planning to Return for 20th NHL Campaign
Carter Hart

Aiming for Sixth Consecutive Win Tuesday
Evgeni Malkin

Inks New One-Year Deal With Penguins
Mackenzie Blackwood

in Net for Game 4 Against Golden Knights
Valeri Nichushkin

a Game-Time Call Tuesday
Nathan MacKinnon

Will Suit Up Tuesday
Ben Griffin

Looking to Repeat This Week at Colonial
Rasmus Hojgaard

a Player to Avoid at Charles Schwab Challenge
Hideki Matsuyama

Needs Solid Driving Week at Charles Schwab Challenge
Justin Thomas

Trending Well Ahead of Charles Schwab Challenge
Akshay Bhatia

Lacking Driving Prowess Needed at Colonial Country Club
CFB

DJ Lagway Looking to Rebound at Baylor
CFB

Josh Hoover Tasked With Leading Indiana Back to the Playoffs
CFB

Braylon Staley the Next 1,000-Yard Tennessee Receiver?
CFB

Ahmad Hardy's Return Timeline Remains Unclear
Evan Mobley

Finishes Season-Ending Loss With 15 Points
James Harden

Wants to Stay in Cleveland
Donovan Mitchell

Remains Committed to Cavaliers
Mikal Bridges

Cools Off in Game 4 Against Cavaliers
OG Anunoby

Active on Both Ends in Blowout Win
Karl-Anthony Towns

Leads Knicks in Scoring During Series-Clincher
Jalen Brunson

Named Eastern Conference Finals MVP
Ivan Demidov

Contributes an Assist in Losing Effort
Lane Hutson

Records Power-Play Goal in Game 3 Loss
Frederik Andersen

Enjoys Another Easy Night at the Office in Game 3
Shayne Gostisbehere

Scores First Postseason Goal
Taylor Hall

Ends Four-Game Goal Drought
Andrei Svechnikov

Scores Game 3 Winner in Overtime
Gage Jump

Athletics to Promote Top Pitching Prospect Gage Jump to Major Leagues
Tatsuya Imai

Two Relievers Combine to No-Hit the Rangers on Monday
Dennis Schröder

Dennis Schroder is Ruled Out for Game 4 on Monday
Michael Porter Jr.

Nets Could Trade Michael Porter Jr.
Valeri Nichushkin

Nathan MacKinnon, Valeri Nichushkin Uncertain for Game 4
Oliver Kapanen

Sitting as Healthy Scratch Monday
Max Domi

Out Indefinitely Due to Offseason Surgery Complications
Dylan Cease

Heading to Injured List With Hamstring Injury
Daniel Suarez

Wins at Charlotte in Rain-Shortened Coca-Cola 600
Christopher Bell

Finishes as the Runner-Up in the Coca-Cola 600 at Charlotte
Denny Hamlin

Falls Short of Winning and Places Third at Charlotte
Tyler Reddick

Places Fourth After Leading Laps at Charlotte
Kyle Larson

Strong and Consistent Day Ends in Fifth at Charlotte
Dylan Cease

Removed From Sunday's Start With Hamstring Discomfort
Vladimir Guerrero Jr.

Exits Sunday's Game Early with Elbow Contusion
MLB

Reds-Cardinals Game Postponed on Sunday
Edward Cabrera

Cubs Place Edward Cabrera on the 15-Day Injured List
Denny Hamlin

the Favorite to Win at Charlotte
Tyler Reddick

on Pole for Coca-Cola 600
Christopher Bell

Could Break Out of Slump
Kyle Larson

May have A Solid Day at Charlotte
Ryan Blaney

Is A DFS Risk for Charlotte Lineups
William Byron

Could have A Great DFS Performance at Charlotte
Chase Briscoe

Is A Solid Tournament Option for Charlotte DFS Lineups
Ty Gibbs

May not be Worth his Salary for Charlotte DFS Lineups
Chris Buescher

May be a Sneaky Tournament Option for Charlotte Lineups
NASCAR

Bubba Wallace Has Favorable Upside for Charlotte DFS Lineups
Ross Chastain

Is A Strong Addition for DFS Lineups at Charlotte
Austin Dillon

Should Fantasy Managers Roster Austin Dillon for Charlotte DFS Lineups?
Chase Elliott

Should Be Strong at Charlotte
Carson Hocevar

Confident for Coca-Cola 600
Corey Heim

a Chalk DFS Pick at Charlotte
Michael McDowell

Is Michael McDowell A Tournament Option for Charlotte Lineups?
MLB

Orioles-Tigers Game Postponed on Saturday
MLB

Rays-Yankees Postponed on Saturday
Mickey Moniak

Heads to Injured List With Ankle Sprain
Jackson Merrill

has Sore Ribs, Expected to Avoid Injured List
CFB

Jaron-Keawe Sagapolutele Looking to Take Sophomore Leap
CFB

Jadan Baugh Primed to Lead Florida Offense in 2026
CFB

LSU Hires Ed Orgeron As Special Assistant
CFB

North Carolina and South Carolina Cancel Home-And-Home Series
CFB

Confidence High in Mississippi State's Kamario Taylor
MLB

Reds-Cardinals Game Postponed on Friday
Trevor Story

has Hernia Surgery, Expected to Miss 6-10 Weeks
Roman Anthony

Dealing With Sprained Ligament in his Finger
Ronald Acuña Jr.

Ronald Acuna Jr. Exits Early, X-Rays Come Back Negative
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF