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Fantasy Aces DFS Advice: Week 10 NFL - Daily Fantasy Football Picks

Matt Terelle's Week 10 daily fantasy football advice and sleepers. NFL DFS lineup picks and value plays for Fantasy Aces at RB, WR, QB, TE, and DEF.

Hey there RotoBallers! In this article I will be taking a look at some of my favorite FantasyAces DFS lineups plays for Week 10 of the NFL slate.

These picks are based on a multitude of factors including matchup, talent, recent performance, and pricing on Fantasy Aces. Let's get to the picks!

Editor's Note: New users that sign up on FantasyAces, make a $20 deposit, and enter any game will receive our full season NFL (or NBA) Premium Pass for free, a $59.99 value. Just email [email protected] with your new FantasyAces username - and boom, that's it! We will email you with your Premium pass.

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Quarterback Plays for Fantasy Aces

Eli Manning (vs. CIN, $6,450)

Manning is coming off one of his best games of the season, throwing for 257 yards, four touchdowns, and two interceptions against the Eagles. While the interceptions weren't ideal, Manning was extremely efficient against an Eagles pass defense that has been stingy against opposing quarterbacks for most of the season. Now he gets to take on a Bengals pass defense that has been one of the best matchups for opposing signal callers on the year. Cincinnati has been getting dismantled through the air this season, allowing 20.04 fantasy points per game to quarterbacks, seventh-highest in the league. I've found the scoring system on Aces favorable for those who search for values at the quarterback position and Eli is one of the top values on the slate. 

Dak Prescott (@ PIT, $6,200)

Prescott's price somehow dropped $250 from last week on Aces, even following his three-touchdown performance against the Browns in Week 9. His upside is just as high this week, but the Cowboys could struggle to play ball-control football against a Pittsburgh offense that can be explosive at home. With Ben Roethlisberger a week healthier, look for the Steelers offense to look much better than it did last week against the Ravens. Prescott, as mentioned above, remains very reasonably priced and sets up as a perfect QB2 on Fantasy Aces for this weekend.

 

Running Back Plays for Fantasy Aces

David Johnson (vs. SF, $6,400)

Johnson is the most expensive back on the slate, but he also has a mouth-watering matchup against a 49ers run defense that has been an absolute disaster this season. San Francisco is fresh off of allowing the Mark Ingram/Tim Hightower duo to combine for 245 rushing yards and three touchdowns in Week 9. Johnson's extensive work in the passing game makes him basically matchup-proof anyway, but it is going to be really hard to keep him out of lineups with the 49ers on the other side of the field. It is doubtful the Cardinals will have to throw very often and Johnson could be deployed in clock-killing mode as early as the third quarter on Sunday. Fade DJ at your own risk this weekend. 

Darren Sproles (vs. ATL, $4,650)

Sproles has emerged as the lead back in Philadelphia, handling 13 of 21 running back carries in Week 9, while also pulling in three receptions. This game should be high-scoring, with the over/under set at a robust 50 points. Furthermore, the Falcons have really struggled to contain opposing pass-catching backs as their pass defense DVOA against running backs ranks just 26th in the league according to Football Outsiders. Sproles' role in the passing game insulates him from becoming a poor game script casualty and keeps his floor high for this matchup which should produce plenty of fantasy goodness for daily players this weekend. 

 

Wide Receiver Plays for Fantasy Aces

Mike Evans (vs. CHI, $5,900)

Evans is coming off a massive Thursday night game which saw him turn 17 targets into 11 catches for 150 yards and two touchdowns, including this beauty for his second score of the night. Evans did enter the concussion protocol after the game, but he's been able to practice thus far and at this point of the week it would be a minor shock if he wasn't able to play in Week 10. The Bears secondary is allowing the sixth-most fantasy points per game to opposing wide receivers on the season. Evans should be in line for another high target volume against Chicago this weekend. 

Alshon Jeffery (@ TB, $4,850)

Jeffery's price is still suppressed, even though he found the end zone for the first time all season in Week 8, the last time Chicago took the field. Jeffery is just the 18th-most expensive wide receiver on Aces this weekend, even though he has the potential to finish as a top-five wideout when all is said and done. The Buccaneers secondary has struggled this season, ranking 20th in DVOA. Rookie cornerback Vernon Hargreaves is expected to spend the majority of his time attempting to slow Jeffery. There is a huge price discrepancy between the two as Hargreaves is 5'10" while Jeffery stands 6'3". This shapes up as a huge mismatch for a star wide receiver who should be peppered with targets from quarterback Jay Cutler

 

Tight End Play for Fantasy Aces

Travis Kelce (@ CAR, $4,700)

Kelce, while he didn't enjoy the officiating last week, did post five catches for 58 yards before getting ejected during the fourth quarter of the Chiefs' win over the Jaguars. Jeremy Maclin, Kansas City's top target, is not expected to play this week after suffering a groin injury during last week's game. That should give Kelce some extra work as he gets set to take on a Panthers defense that is allowing the third-most fantasy points per game to tight ends this season. Add in the fact that Carolina is stout against opposing run games and we should see the Chiefs throwing more often than they usually prefer to.  

 

Defense/Special Teams Play for Fantasy Aces

Washington Redskins (vs. MIN, $2,700)

The Redskins defense could be a sneaky start this weekend as they have a nice shot at performing and could be lightly owned in the Week 10 slate. Minnesota's offense has been struggling, to say the least, over their three-game losing streak, scoring just 36 points over that span. Washington's defense has struggled against opposing run games, but Minnesota's weak offensive line has rendered their run game practically useless, so it is doubtful the Vikings will be able to take advantage of the Redskins' weakness in that facet of the game. Washington is a -2.5 point favorite at home, against a bad offense, in a game that should be low-scoring, making them a prime target for daily leagues.




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REAL-TIME FANTASY NEWS

Bo Bichette

Yankees Showing Interest in Bo Bichette
D'Angelo Russell

Ruled Out Thursday With Illness
George Kittle

Listed as Questionable for Week 18
Alperen Sengün

Alperen Sengun Active Versus Nets
Amon-Ra St. Brown

Trending Towards Playing
Clint Capela

Steven Adams and Clint Capela Sidelined Thursday
Miles Wood

Blue Jackets Place Miles Wood on Injured Reserve
Dak Prescott

May Not Play Full Game in Week 18
Conor Garland

to Miss One Week
Egor Demin

Won't Suit Up Against Houston
Marco Rossi

to Miss at Least One Week
Ace Bailey

Still Out on Thursday Night
Tari Eason

Active on Thursday
Yegor Chinakhov

Set for Penguins Debut Thursday
Lauri Markkanen

Ruled Out on Thursday
Tanner McKee

Will Start for Eagles in Week 18
Shayne Gostisbehere

Misses Third Consecutive Game Thursday
Keyonte George

Unavailable on Thursday
Michael Porter Jr.

Out on Thursday
Auston Matthews

Returns From One-Game Absence
Josh Allen

Trending Towards Resting in Week 18
William Nylander

Remains Out Thursday
Lamar Jackson

Will Officially Return in Week 18
Tobias Harris

Won't Suit Up Against Miami
Lauri Markkanen

on the Injury Report for Thursday Night
Keyonte George

Battling an Illness, Might Miss Thursday's Game
Jusuf Nurkić

Jusuf Nurkic Won't Play on Thursday Evening
Houston Astros

Astros Sign Tatsuya Imai to Three-Year Deal
Jordan Love

Clears Concussion Protocol, Won't Start in Week 18
George Kittle

"Absolutely" Expects to Play in Week 18
Clayton Tune

to Start for Packers in Week 18
Chris Olave

Ruled Out for Week 18
Tom Wilson

Wraps Up 2025 With Gordie Howe Hat Trick
Valeri Nichushkin

Nets Second Career Hat Trick
Frank Vatrano

to Miss Six Weeks With Shoulder Injury
Conor Sheary

Noah Laba Exit With Injuries Wednesday
Brayden McNabb

Suffers Upper-Body Injury Wednesday
Miles Wood

Exits Early Wednesday
Gavin Brindley

Sustains Upper-Body Injury
Michael Porter Jr.

Battling Illness, Questionable Thursday
Joel Embiid

Likely to Play Thursday
Anthony Davis

Available Thursday
Coby White

to Miss at Least One Week
Josh Giddey

to Be Re-Evaluated in Two Weeks
Jonas Valančiūnas

Jonas Valanciunas in Walking Boot After Suffering Calf Injury
Victor Wembanyama

Expects to Play Next Game After Suffering Minor Knee Injury
Davante Adams

Not Expected to Play in Week 18
Stephon Castle

Active on Wednesday
Geno Smith

Won't Play in Week 18
Aaron Rodgers

Considering Playing Beyond 2025?
Sean Monahan

Sits Out Wednesday's Game
Zach Werenski

Misses Fourth Straight Game Wednesday
Dougie Hamilton

Questionable Wednesday
Radko Gudas

Expected to Remain Out Wednesday
Stefon Diggs

Expected to Play in Week 18
Ilya Lyubushkin

Back From One-Game Absence Wednesday
Alex Lyon

to Miss "Bit of Time"
Erik Cernak

Rejoins Lightning Lineup Wednesday
Christian McCaffrey

Trending to Play in Week 18
Jalen Hurts

Eagles Expected to Rest Jalen Hurts, Most Starters in Week 18
George Kittle

49ers Will be "Very Surprised" if George Kittle Doesn't Play on Saturday
Marvin Harrison Jr.

Ruled Out for Regular-Season Finale
CFB

Lane Kiffin Interested in Sam Leavitt, Brendan Sorsby at LSU
CFB

Deuce Knight Officially Entering Transfer Portal
CFB

Kewan Lacy Expected to Be Full-Go Against Georgia
Stefon Diggs

Facing Strangulation, Assault Charges
CFB

Chip Kelly Named Northwestern Offensive Coordinator
Riley Leonard

Will Start Against the Texans
Bijan Robinson

Explodes for 229 Total Yards, Two Touchdowns on Monday Night
CFB

Penn State Working to Hire D'Anton Lynn as Next Defensive Coordinator
CFB

Omar Cooper Expected to be Full-Go for Rose Bowl
CFB

Marcus Freeman Staying with Notre Dame for 2026 Season
CFB

Star Wideout Cam Coleman Entering Transfer Portal
CFB

Jay Hill Expected to be Next Michigan Defensive Coordinator

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