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FanPicks NFL DFS Lineup Picks for Week 2

RotoBallers, welcome to the show. This year we're partnering with our friends from FanPicks. We'll be running all sorts of promos and fun DFS contests, including weekly freerolls, so stay tuned.

In this column, you will find my recommended FanPicks DFS Lineup Picks to target for Week 2 of the NFL season. The goal is to identify players to start on FanPicks this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the FanPicks price.

Let's find some DFS lineup sleepers, and win on FanPicks. Good luck in Week 2!

Be sure to check all of our fantasy football rankings for 2025:

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FanPicks Quarterbacks - Week 2 DFS Picks

Jimmy Garoppolo - vs DET ($5,400)

Garoppolo struggled in his first game, but there is a big difference between the Detroit Lions secondary and the Minnesota Vikings in Minnesota. Sam Darnold completed 16 of 21 attempts for 198 yards, two touchdowns, and one interception on Monday night. That game was out of hand quickly, or he likely could have continued to find success. The San Francisco 49ers are also -6 point favorites in a game set at 48 points, giving them an implied total of 27 points.

 

FanPicks Running Backs - Week 2 DFS Picks

James Conner - vs KC ($5,800)

Conner has taken over for Le'Veon Bell, who is expected to miss the game this week, as well. Conner saw 36 touches last week, totaling 192 yards and two touchdowns. He should see another massive role in this game, which will be extremely high scoring. Kansas City gave up plenty of fantasy points to Melvin Gordon and Austin Ekeler last week, and Conner could find similar success. He'll feature a ton of ownership, and for good reason.

Carlos Hyde - at NO ($4,900)

Hyde struggled in his game last week, but he saw 22 carries in that game. He was the lead running back in Cleveland, and that should be the case again this week. He gets a solid matchup against the New Orleans Saints in a game that should feature a ton of scoring. Hyde has a nose for the end zone, and he's one of Cleveland's greatest threats near the goal line. He's surprisingly cheap, making him a great option in all leagues.

 

FanPicks Wide Receivers - Week 2 DFS Picks

Odell Beckham Jr. - at DAL ($6,500)

Beckham had one of the hardest matchups on the slate against Jalen Ramsey, but he still recorded 11 receptions for 111 yards on 15 targets. He's a massive part of the Giants offense, and he'll get a significantly easier matchup this week. Beckham is the cheapest of the elite options on the slate. He'll continue to get better as he returns to game form, and OBJ can safely be used in all leagues.

Kenny Golladay - at SF ($4,500)

Golladay's role in the offense is a bit unknown at this point. It looks like he'll continue to play in two receiver sets, and he was a major part of the offense last week. In his first game of the season, Golladay posted a 7/114 line on 12 targets. He's a red zone threat because of his size, and Gollday is a great option that is seemingly flying under the radar.

 

FanPicks Tight End - Week 2 DFS Pick

Jared Cook - at DEN ($3,300)

Cook was a featured player in the Oakland offense last week, catching nine passes for 180 yards on 12 targets. He gets a matchup against the Denver Broncos, who have struggled at times against tight ends. Cook could see a slight downtick in targets as the season progresses, but he could potentially see double digit targets once again. He's a cheap option with a high floor and even higher ceiling.

 

FanPicks Defense - Week 2 DFS Pick

Los Angeles Chargers - at BUF ($3,400)

The Buffalo Bills feature the worst offense in the NFL. They scored only three points in the opener, and they will now get a matchup against the Los Angeles Chargers, who feature arguably the best secondary in the NFL. Josh Allen will draw the start, and he's a bit known for being careless with the football. The Bills own an implied total of only 17.5 points, which is the second lowest on the slate. Los Angeles is a safe play at defense.

 

More Weekly DFS Analysis




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REAL-TIME FANTASY NEWS

Gradey Dick

Injured on Wednesday
RJ Barrett

to Be Re-Evaluated in One Week
Anthony Davis

on the Cusp of Returning
Gary Payton II

Hurt in Wednesday's Loss
Stephen Curry

Diagnosed With Quadriceps Contusion
Alvin Kamara

Doesn't Practice on Wednesday
Lukas Dostal

Out Wednesday Night
Sean Durzi

Available Against Canadiens
Thomas Chabot

to Remain Out Wednesday
Jared McCann

Expected to Rejoin Kraken Lineup Wednesday
Andre Burakovsky

a Game-Time Decision Wednesday
Zach Edey

Good to Go Versus New Orleans
Mikko Rantanen

Returns to Stars Lineup Wednesday
J.K. Dobbins

Could Return Later This Season
Shai Gilgeous-Alexander

Available on Wednesday
Mark Stone

Ready to Return Wednesday
Nikola Jović

Nikola Jovic Good to go on Wednesday
Dylan Cease

Agrees With Blue Jays on Seven-Year, $210 Million Deal
Norman Powell

Back in Action Wednesday
Giannis Antetokounmpo

Ruled Out on Wednesday Evening
Andrew Wiggins

Will Suit Up Against Milwaukee
Shai Gilgeous-Alexander

a Game-Time Decision on Wednesday
Terry McLaurin

Plans to Play on Sunday Night
Dru Smith

Available Versus Bucks
Miami Heat

Jamie Jaquez Jr. Available for Wednesday's Matchup With Milwaukee
Jaime Jaquez Jr.

Upgraded to Probable Against Bucks
Pat Connaughton

Sidelined on Wednesday
Dylan Harper

Set to Suit Up Wednesday
Jonathan Kuminga

Sent to G League on Wednesday
Landry Shamet

Sidelined at Least Four Weeks
Anthony Rendon

Angels Could Buy Out Final Year of Anthony Rendon's Contract
Brandon Aiyuk

49ers Won't Open Brandon Aiyuk's Practice Window This Week
Joe Burrow

Bengals Officially Activate Joe Burrow for a Return on Thanksgiving
C.J. Stroud

Practicing Wednesday
Trey Benson

Spotted at Practice on Wednesday
Marvin Harrison Jr.

Back at Practice Wednesday
DeVonta Smith

Missing From Practice Again on Wednesday
Josh Hader

Says his Shoulder is "Back to Normal"
Ketel Marte

Diamondbacks "Actively Listening" on Ketel Marte
Jaxson Dart

to be a Full Participant at Wednesday's Practice
Dalton Kincaid

has "a Chance" to Play in Week 13
Drake London

"Doubtful" to Return from Knee Injury in Week 13
Jayden Daniels

Could Return in Week 14
Aaron Rodgers

Slated to Return in Week 13
Baker Mayfield

Could Play This Week
Josh Jacobs

"Good to Go" in Pivotal NFC North Matchup on Thanksgiving
Steven Adams

Ruled Out Wednesday Against Warriors
George Pickens

Expected to Play Thursday Against the Chiefs
J.J. McCarthy

Not Expected to Play Sunday in Seattle
Dennis Schröder

Dennis Schroder Questionable With Hip Soreness On Wednesday
Josh Norris

Nearing Return
Kevin Lankinen

Not Traveling With Canucks
Zach Werenski

Escapes Serious Injury, May Play Wednesday
Auston Matthews

Could Be an Option Wednesday
Jason Robertson

Scores in Seventh Consecutive Game
Wyatt Johnston

Ends Dry Spell With Four-Point Performance
DeVonta Smith

Listed as DNP on Tuesday
Vinnie Hinostroza

to Miss 4-6 Weeks
Pyotr Kochetkov

Dealing With Undisclosed Injury
Tristan Jarry

Expected to Be Available Wednesday
Evgenii Dadonov

Doubtful for Wednesday
J.T. Miller

Joins Team for Road Trip
Joel Kiviranta

Ready to Return Wednesday
Ryan Nugent-Hopkins

Expected to Return on Saturday
Jauan Jennings

Won't be Suspended
Omarion Hampton

Chargers Open Omarion Hampton's Practice Window
J.T. Realmuto

Red Sox Showing Interest in J.T. Realmuto
Sonny Gray

Red Sox Acquire Sonny Gray From the Cardinals
CFB

Jeremiah Smith, Makai Lemon, Skyler Bell Named Biletnikoff Award Finalists
Sam Reinhart

Extends Scoring Streak With Three-Point Effort
Shohei Ohtani

to Play for Team Japan in 2026 World Baseball Classic
Colorado Rockies

Warren Schaeffer to Stick Around as Rockies Manager in 2026
CFB

Chris Bell Out for Rivalry Matchup Against Kentucky
Ryan Helsley

Tigers Eyeing Ryan Helsley as a Starter
Dan Hooker

Suffers Second-Round Submission Loss
Marcus Semien

Shipped to the Mets on Sunday
Arman Tsarukyan

Gets Submission Win
Brandon Nimmo

Traded to Texas
Belal Muhammad

Loses Back-to-Back Fights
Belal Muhammad

Ian Machado Garry Outpoints Belal Muhammad
Alonzo Menifield

Suffers First-Round Knockout Loss
Volkan Oezdemir

Gets Back In The Win Column
Jack Hermansson

Gets Knocked Out
Jack Hermansson

Myktybek Orolbai Knocks Out Jack Hermansson
Shamil Gaziev

Suffers First-Round Knockout Loss
Waldo Cortes-Acosta

Shines At UFC Qatar
Tagir Ulanbekov

Suffers Third-Round Submission Loss
Kyoji Horiguchi

Makes Triumphant UFC Return
Adolis García

Rangers Non-Tender Adolis Garcia on Friday
CFB

Beau Pribula Expected to Start Against Oklahoma
Dan Hooker

An Underdog At UFC Qatar
Arman Tsarukyan

Looks To Extend His Win Streak
Ian Machado Garry

A Favorite At UFC Qatar
Belal Muhammad

Looks To Bounce Back
Alonzo Menifield

Looks For His Third Consecutive Win
Volkan Oezdemir

Looks To Get Back In The Win Column
Myktybek Orolbai

Looks To Win Back-To-Back Fights
Jack Hermansson

Makes His Welterweight Debut
Kyoji Horiguchi

Returns To The UFC

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