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FanPicks NFL DFS Lineup Picks for Week 2

RotoBallers, welcome to the show. This year we're partnering with our friends from FanPicks. We'll be running all sorts of promos and fun DFS contests, including weekly freerolls, so stay tuned.

In this column, you will find my recommended FanPicks DFS Lineup Picks to target for Week 2 of the NFL season. The goal is to identify players to start on FanPicks this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the FanPicks price.

Let's find some DFS lineup sleepers, and win on FanPicks. Good luck in Week 2!

Be sure to check all of our fantasy football rankings for 2025:

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FanPicks Quarterbacks - Week 2 DFS Picks

Jimmy Garoppolo - vs DET ($5,400)

Garoppolo struggled in his first game, but there is a big difference between the Detroit Lions secondary and the Minnesota Vikings in Minnesota. Sam Darnold completed 16 of 21 attempts for 198 yards, two touchdowns, and one interception on Monday night. That game was out of hand quickly, or he likely could have continued to find success. The San Francisco 49ers are also -6 point favorites in a game set at 48 points, giving them an implied total of 27 points.

 

FanPicks Running Backs - Week 2 DFS Picks

James Conner - vs KC ($5,800)

Conner has taken over for Le'Veon Bell, who is expected to miss the game this week, as well. Conner saw 36 touches last week, totaling 192 yards and two touchdowns. He should see another massive role in this game, which will be extremely high scoring. Kansas City gave up plenty of fantasy points to Melvin Gordon and Austin Ekeler last week, and Conner could find similar success. He'll feature a ton of ownership, and for good reason.

Carlos Hyde - at NO ($4,900)

Hyde struggled in his game last week, but he saw 22 carries in that game. He was the lead running back in Cleveland, and that should be the case again this week. He gets a solid matchup against the New Orleans Saints in a game that should feature a ton of scoring. Hyde has a nose for the end zone, and he's one of Cleveland's greatest threats near the goal line. He's surprisingly cheap, making him a great option in all leagues.

 

FanPicks Wide Receivers - Week 2 DFS Picks

Odell Beckham Jr. - at DAL ($6,500)

Beckham had one of the hardest matchups on the slate against Jalen Ramsey, but he still recorded 11 receptions for 111 yards on 15 targets. He's a massive part of the Giants offense, and he'll get a significantly easier matchup this week. Beckham is the cheapest of the elite options on the slate. He'll continue to get better as he returns to game form, and OBJ can safely be used in all leagues.

Kenny Golladay - at SF ($4,500)

Golladay's role in the offense is a bit unknown at this point. It looks like he'll continue to play in two receiver sets, and he was a major part of the offense last week. In his first game of the season, Golladay posted a 7/114 line on 12 targets. He's a red zone threat because of his size, and Gollday is a great option that is seemingly flying under the radar.

 

FanPicks Tight End - Week 2 DFS Pick

Jared Cook - at DEN ($3,300)

Cook was a featured player in the Oakland offense last week, catching nine passes for 180 yards on 12 targets. He gets a matchup against the Denver Broncos, who have struggled at times against tight ends. Cook could see a slight downtick in targets as the season progresses, but he could potentially see double digit targets once again. He's a cheap option with a high floor and even higher ceiling.

 

FanPicks Defense - Week 2 DFS Pick

Los Angeles Chargers - at BUF ($3,400)

The Buffalo Bills feature the worst offense in the NFL. They scored only three points in the opener, and they will now get a matchup against the Los Angeles Chargers, who feature arguably the best secondary in the NFL. Josh Allen will draw the start, and he's a bit known for being careless with the football. The Bills own an implied total of only 17.5 points, which is the second lowest on the slate. Los Angeles is a safe play at defense.

 

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REAL-TIME FANTASY NEWS

Quentin Grimes

Unavailable on Tuesday
Paul George

Available to Play on Tuesday
LaMelo Ball

Expected to Play on Wednesday
Brandon Miller

Ruled Out for Wednesday's Game
Kristaps Porzingis

Sidelined Again for Wednesday
Kyshawn George

Upgraded to Available on Tuesday
Giannis Antetokounmpo

Expected to Suit Up Wednesday
Nathan Walker

Out for Eight Weeks
Lian Bichsel

to Sit Out 6-8 Weeks
Viktor Arvidsson

Activated From Injured Reserve
Warren Foegele

Remains Out Tuesday
Nikola Jokić

Nikola Jokic Probable for Wednesday
Valeri Nichushkin

Available After Eight-Game Absence
Gabriel Landeskog

Nathan MacKinnon, Gabriel Landeskog Cleared for Tuesday
Jamal Murray

Questionable for Wednesday
Tyson Foerster

to Miss 2-3 Months
CFB

D.J. Durkin Staying at Auburn Under Alex Golesh
Alexandre Sarr

Out of Action Again on Tuesday
Zion Williamson

Sidelined at Least Three Weeks
CFB

Charlie Weis Jr. Permitted to Coach Ole Miss Offense in College Football Playoff
Khris Middleton

Will Not Play Tuesday
Kyshawn George

Is Questionable Against the 76ers
Tyrone Tracy Jr.

Says he's Fine After Suffering Hip Contusion
Trey Murphy III

Will Return Tuesday Night
Omarion Hampton

Likely to Return in Week 14
Yves Missi

Uncertain to Play Tuesday Against the Timberwolves
Zion Williamson

Questionable Against Minnesota
Neemias Queta

Set to Return on Tuesday
Derrick White

Will Play Tuesday Against New York
Quentin Grimes

Downgraded to Questionable on Tuesday
CFB

Five-Star Quarterback Jared Curtis Flips Commitment From Georgia to Vanderbilt
CFB

Florida Hiring Brad White as Defensive Coordinator
Kyle Schwarber

Giants Have Checked in on Kyle Schwarber
Willson Contreras

Willing to Waive his Full No-Trade Clause?
Brandon Aiyuk

49ers "Hopeful" Brandon Aiyuk Will Play in 2025
Brayden Point

Without Timetable for Return
Jake Walman

Still Out Tuesday
Mason Appleton

Misses Tuesday's Contest
Oliver Ekman-Larsson

Good to Go Tuesday
Conor Garland

Out on Tuesday
Petr Mrazek

Considered Day-to-Day
Tyson Foerster

Hurt in Monday's Loss
Trey Murphy III

May Skip Another Game Tuesday
Zion Williamson

Back in Pelicans Lineup Tuesday
Tyrone Tracy Jr.

Carted Off With Hip Injury on Monday Night
Edwin Díaz

Mets Still Interested in Re-Signing Edwin Diaz
Devin Williams

Agrees to Three-Year Deal With Mets
Cole Ragans

Red Sox Targeting Cole Ragans in a Trade?
CFB

Kentucky Hires Oregon Offensive Coordinator Will Stein As Head Coach
Davante Adams

Not Dealing With a Serious Injury
Kyler Murray

Surgery Not on the Table for Kyler Murray
Marvin Harrison Jr.

in Danger of Missing Week 14?
Danila Yurov

Won't Play on Tuesday
David Pastrnak

to Remain Out Tuesday
Adam Gaudette

Iffy for Monday
CFB

Kalani Sitake the Top Target for Penn State Coaching Job
Logan Cooley

a Game-Time Decision Monday
Josh Norris

Available Monday
Neal Pionk

Remains Out Monday
Jimmy Snuggerud

to Miss Six Weeks After Wrist Surgery
Justin Herbert

Having Hand Surgery on Monday
Kyler Murray

Cardinals Won't Open Kyler Murray's Practice Window This Week
Sauce Gardner

Not a Candidate to Go on Injured Reserve
Jayden Daniels

Not Cleared for Contact, Decision on Week 14 Status Delayed
CFB

Josh Heupel Says He's Not a Candidate for Penn State Head Coach Job
Trey Hendrickson

Doubtful to Return in Week 14
Tee Higgins

Still in the Concussion Protocol
Drake London

"has a Chance" to Play in Week 14
J.J. McCarthy

in Line to Start in Week 14?
Aaron Jones Sr.

Not Dealing With Serious Shoulder Injury, Likely Day-to-Day
Sam Darnold

Dealing With Ankle Injury, "Should be Good" for Week 14
CFB

Will Stein, Brian Hartline the Top Candidates for Kentucky Job?
CFB

Nebraska Fires Defensive Coordinator John Butler After One Season
CFB

UCLA Expected to Hire Bob Chesney as Next Head Coach
Sauce Gardner

Officially Week-to-Week with Strained Calf
CFB

Lane Kiffin to Make $13 Million Salary, Ties Kirby Smart
CFB

Buster Faulkner, Joey Halzle Candidates for Florida Offensive Coordinator Job?
CFB

Kentucky Officially Fires Mark Stoops
Justin Herbert

Has Metacarpal Fracture in Left Hand
Amon-Ra St. Brown

Week 14 Availability Up in the Air
Zach Ertz

Leads Washington in Receiving in Overtime Loss
CFB

Lane Kiffin to be Introduced as LSU's Next Head Coach on Monday
CFB

Florida Poised to Land Jon Sumrall as Next Head Coach
CFB

Alex Golesh Taking Over Auburn Head-Coaching Job
CFB

Arkansas Expected to Hire Ryan Silverfield as Next Head Coach
Zack Wheeler

Likely to Return in May
Ryan Helsley

Agrees to Two-Year Deal With Orioles

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