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FanPicks NFL DFS Lineup Picks for Week 2

RotoBallers, welcome to the show. This year we're partnering with our friends from FanPicks. We'll be running all sorts of promos and fun DFS contests, including weekly freerolls, so stay tuned.

In this column, you will find my recommended FanPicks DFS Lineup Picks to target for Week 2 of the NFL season. The goal is to identify players to start on FanPicks this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the FanPicks price.

Let's find some DFS lineup sleepers, and win on FanPicks. Good luck in Week 2!

Be sure to check all of our fantasy football rankings for 2025:

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FanPicks Quarterbacks - Week 2 DFS Picks

Jimmy Garoppolo - vs DET ($5,400)

Garoppolo struggled in his first game, but there is a big difference between the Detroit Lions secondary and the Minnesota Vikings in Minnesota. Sam Darnold completed 16 of 21 attempts for 198 yards, two touchdowns, and one interception on Monday night. That game was out of hand quickly, or he likely could have continued to find success. The San Francisco 49ers are also -6 point favorites in a game set at 48 points, giving them an implied total of 27 points.

 

FanPicks Running Backs - Week 2 DFS Picks

James Conner - vs KC ($5,800)

Conner has taken over for Le'Veon Bell, who is expected to miss the game this week, as well. Conner saw 36 touches last week, totaling 192 yards and two touchdowns. He should see another massive role in this game, which will be extremely high scoring. Kansas City gave up plenty of fantasy points to Melvin Gordon and Austin Ekeler last week, and Conner could find similar success. He'll feature a ton of ownership, and for good reason.

Carlos Hyde - at NO ($4,900)

Hyde struggled in his game last week, but he saw 22 carries in that game. He was the lead running back in Cleveland, and that should be the case again this week. He gets a solid matchup against the New Orleans Saints in a game that should feature a ton of scoring. Hyde has a nose for the end zone, and he's one of Cleveland's greatest threats near the goal line. He's surprisingly cheap, making him a great option in all leagues.

 

FanPicks Wide Receivers - Week 2 DFS Picks

Odell Beckham Jr. - at DAL ($6,500)

Beckham had one of the hardest matchups on the slate against Jalen Ramsey, but he still recorded 11 receptions for 111 yards on 15 targets. He's a massive part of the Giants offense, and he'll get a significantly easier matchup this week. Beckham is the cheapest of the elite options on the slate. He'll continue to get better as he returns to game form, and OBJ can safely be used in all leagues.

Kenny Golladay - at SF ($4,500)

Golladay's role in the offense is a bit unknown at this point. It looks like he'll continue to play in two receiver sets, and he was a major part of the offense last week. In his first game of the season, Golladay posted a 7/114 line on 12 targets. He's a red zone threat because of his size, and Gollday is a great option that is seemingly flying under the radar.

 

FanPicks Tight End - Week 2 DFS Pick

Jared Cook - at DEN ($3,300)

Cook was a featured player in the Oakland offense last week, catching nine passes for 180 yards on 12 targets. He gets a matchup against the Denver Broncos, who have struggled at times against tight ends. Cook could see a slight downtick in targets as the season progresses, but he could potentially see double digit targets once again. He's a cheap option with a high floor and even higher ceiling.

 

FanPicks Defense - Week 2 DFS Pick

Los Angeles Chargers - at BUF ($3,400)

The Buffalo Bills feature the worst offense in the NFL. They scored only three points in the opener, and they will now get a matchup against the Los Angeles Chargers, who feature arguably the best secondary in the NFL. Josh Allen will draw the start, and he's a bit known for being careless with the football. The Bills own an implied total of only 17.5 points, which is the second lowest on the slate. Los Angeles is a safe play at defense.

 

More Weekly DFS Analysis




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REAL-TIME FANTASY NEWS

Collin Murray-Boyles

Questionable for Thursday
Zion Williamson

Cleared for Contact
LeBron James

Practices With G League Team
Christian Braun

Leaves Game with Ankle Injury
Jalen Brunson

Leaves The Garden in Walking Boot
Félix Bautista

Felix Bautista Could Return in Second Half in 2026
Kodai Senga

Attracting Trade Interest, Will the Mets Move him?
Jonathan Kuminga

Won't Return on Wednesday Evening
Paolo Banchero

Ruled Out for Remainder of Wednesday's Game
Yordan Alvarez

Expected to be Ready for Spring Training
Byron Buxton

Could Waive his No-Trade Clause
Paul Skenes

the Unanimous NL Cy Young Winner
Tarik Skubal

Wins AL Cy Young for Second Straight Year
Bilal Coulibaly

Without A Timetable For Return
Nickeil Alexander-Walker

Upgraded To Probable For Matchup Versus Kings
Jonathan Kuminga

Active Wednesday, Not In Starting Lineup
Dereck Lively II

Downgraded to Unavailable on Wednesday
Ja Morant

Unavailable Wednesday
Sam LaPorta

Misses Practice With Back Injury Wednesday
Isaiah Stewart

Sidelined Again on Wednesday
Jalen Duren

Downgraded Versus Chicago
Cade Cunningham

Ruled Out On Wednesday
Ryan Kalkbrenner

Available to Suit Up Wednesday
Zach LaVine

Won't Play on Wednesday Evening
Josh Giddey

Sidelined on Wednesday
J.K. Dobbins

Not Practicing, IR Move Undecided
Zach Hyman

Nearing Season Debut
Davante Adams

Out Wednesday, Expected to Play in Week 11
Colten Ellis

to Make Second Career Start Wednesday
Adam Erne

to Miss "a Few Weeks"
Paul George

Moving Closer to Return
Tyson Foerster

on Track to Return Wednesday
Joel Embiid

Showing No Structural Issues in Right Knee
Kayshon Boutte

Ruled Out for Thursday Night
Andre Burakovsky

a Game-Time Call Wednesday
Frank Nazar

Out on Wednesday
Rhamondre Stevenson

Ruled Out For Thursday
Brock Purdy

Working Toward Starting Sunday
Giannis Antetokounmpo

Sidelined on Wednesday
C.J. Stroud

Not at Practice, Set for Another Missed Game?
J.J. McCarthy

Nursing Hand Injury, Set to Play on Sunday
Romeo Doubs

"Should be Good to Go" on Sunday
Rico Dowdle

Held Out on Wednesday, Should Fantasy Managers be Worried?
Lamar Jackson

has Knee Soreness, "Should be Good" for Week 11
Garrett Wilson

Officially Ruled Out for Thursday Night
Brian Thomas Jr.

Practicing, on Track to Return in Week 11?
Joe Burrow

Looking Sharp at Practice
Isiah Pacheco

Won't Practice on Wednesday
Calvin Ridley

Back at Wednesday's Practice
Chris Godwin

"Making Good Strides" and "Running"
Jaxson Dart

in Concussion Protocol, Won't Start in Week 11
Jameis Winston

Will Start in Week 11 for Giants
Dalton Kincaid

Won't Practice on Wednesday
CFB

Still No Update on Jermod McCoy's Return Timeline
Rhamondre Stevenson

Expected to Reclaim Lead-Back Role When Healthy?
Sami Valimaki

Riding Momentum Into Bermuda
Matthieu Pavon

Struggling Through a Rough Season
Taylor Montgomery

Hopes to Get Back on Track at Port Royal
Ben Martin

a Risky Play at Bermuda Championship
Mark Hubbard

Primed for a Bounce-Back Week in Bermuda
Boone Jenner

Exits Win With Upper-Body Injury
Lee Hodges

Searching for a Spark in Bermuda
Frederik Andersen

Pulled by Concussion Spotter
Valeri Nichushkin

Sustains Lower-Body Injury in Win
Thatcher Demko

Suffers Lower-Body Injury Tuesday
Thomas Chabot

Injured Versus Stars
Anthony Stolarz

Exits Early Tuesday
Auston Matthews

Hurt in Tuesday's Loss
Stephen Vogt

Wins Back-to-Back AL Manager of the Year Honors
Milwaukee Brewers

Pat Murphy Named NL Manager of the Year Again
Patrick Fishburn

Looking to Bounce Back in Bermuda
Eric Cole

Carrying Momentum into Bermuda
Tommy Edman

to Have Ankle Surgery Next Week
Ketel Marte

Diamondbacks Unlikely to Trade Ketel Marte
Roman Anthony

to Have a Normal Offseason
Jarren Duran

Red Sox Think Jarren Duran Needs a Fresh Start
MacKenzie Gore

Nationals Expected to Trade MacKenzie Gore?
Sahith Theegala

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Sam Stevens

Finishes Tied for 36th at Baycurrent Classic
Patrick Rodgers

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Luke List

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Ben Kohles

Finishes Tied for 63rd at World Wide Technology Championship
PGA

Nico Echavarria Finishes Tied for 14th at World Wide Technology Championship
Luke Clanton

Finishes Tied for 46th at World Wide Technology Championship
Blades Brown

Finishes Tied for 18th at Korn Ferry Tour Championship
Victor Hedman

Iffy for Wednesday
Ryan McDonagh

to Sit Out "a Few Games"
Charlie McAvoy

Back in Action Tuesday
Scott Laughton

Unavailable Tuesday
Ryan Strome

Won't Play Tuesday
Shayne Gostisbehere

Ready to Face Capitals
Thatcher Demko

Returns to Canucks Crease Tuesday
Tarik Skubal

Tigers Unlikely to Trade Tarik Skubal
Framber Valdez

Cubs Could Land Framber Valdez in Free Agency
Jake Walman

Plays Key Role in Comeback Victory
Sandy Alcantara

Marlins Ready to Trade Sandy Alcantara
Ketel Marte

Diamondbacks Motivated to Move Ketel Marte
Hunter Greene

Reds to Listen to Offers on Hunter Greene
Paul Skenes

Pirates Won't Trade Paul Skenes
Pete Alonso

Mets Expected to Let Pete Alonso Walk in Free Agency
Kyle Tucker

to Sign With Yankees, Blue Jays, or Dodgers
CFB

Nic Anderson Could Return for LSU this Season
Randy Brown

Suffers Second-Round TKO Loss
Gabriel Bonfim

Extends His Win Streak
Joseph Morales

Gets First-Round Submission Win
Matt Schnell

Suffers First-Round Submission Loss
Muslim Salikhov

Suffers First-Round TKO Loss
Uros Medic

Wins Back-To-Back Fights
Ismael Bonfim

Loses Back-to-Back Fights
Chris Padilla

Remains Unbeaten In The UFC
Marco Tulio

Suffers His First UFC Loss
Christian Leroy Duncan

Scores Second-Round Knockout Victory
Randy Brown

Set For UFC Vegas 111 Main Event
Gabriel Bonfim

Looks To Extend His Win Streak
Joseph Morales

A Favorite At UFC Vegas 111
Matt Schnell

Set For UFC Vegas 111 Co-Main Event
Uros Medic

Aims To Win Back-To-Back Fights
Muslim Salikhov

Looks For His Fourth Consecutive Win
Chris Padilla

Looks To Remain Unbeaten In The UFC

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