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FanPicks NFL DFS Lineup Picks for Week 2

RotoBallers, welcome to the show. This year we're partnering with our friends from FanPicks. We'll be running all sorts of promos and fun DFS contests, including weekly freerolls, so stay tuned.

In this column, you will find my recommended FanPicks DFS Lineup Picks to target for Week 2 of the NFL season. The goal is to identify players to start on FanPicks this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the FanPicks price.

Let's find some DFS lineup sleepers, and win on FanPicks. Good luck in Week 2!

Be sure to check all of our fantasy football rankings for 2025:

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FanPicks Quarterbacks - Week 2 DFS Picks

Jimmy Garoppolo - vs DET ($5,400)

Garoppolo struggled in his first game, but there is a big difference between the Detroit Lions secondary and the Minnesota Vikings in Minnesota. Sam Darnold completed 16 of 21 attempts for 198 yards, two touchdowns, and one interception on Monday night. That game was out of hand quickly, or he likely could have continued to find success. The San Francisco 49ers are also -6 point favorites in a game set at 48 points, giving them an implied total of 27 points.

 

FanPicks Running Backs - Week 2 DFS Picks

James Conner - vs KC ($5,800)

Conner has taken over for Le'Veon Bell, who is expected to miss the game this week, as well. Conner saw 36 touches last week, totaling 192 yards and two touchdowns. He should see another massive role in this game, which will be extremely high scoring. Kansas City gave up plenty of fantasy points to Melvin Gordon and Austin Ekeler last week, and Conner could find similar success. He'll feature a ton of ownership, and for good reason.

Carlos Hyde - at NO ($4,900)

Hyde struggled in his game last week, but he saw 22 carries in that game. He was the lead running back in Cleveland, and that should be the case again this week. He gets a solid matchup against the New Orleans Saints in a game that should feature a ton of scoring. Hyde has a nose for the end zone, and he's one of Cleveland's greatest threats near the goal line. He's surprisingly cheap, making him a great option in all leagues.

 

FanPicks Wide Receivers - Week 2 DFS Picks

Odell Beckham Jr. - at DAL ($6,500)

Beckham had one of the hardest matchups on the slate against Jalen Ramsey, but he still recorded 11 receptions for 111 yards on 15 targets. He's a massive part of the Giants offense, and he'll get a significantly easier matchup this week. Beckham is the cheapest of the elite options on the slate. He'll continue to get better as he returns to game form, and OBJ can safely be used in all leagues.

Kenny Golladay - at SF ($4,500)

Golladay's role in the offense is a bit unknown at this point. It looks like he'll continue to play in two receiver sets, and he was a major part of the offense last week. In his first game of the season, Golladay posted a 7/114 line on 12 targets. He's a red zone threat because of his size, and Gollday is a great option that is seemingly flying under the radar.

 

FanPicks Tight End - Week 2 DFS Pick

Jared Cook - at DEN ($3,300)

Cook was a featured player in the Oakland offense last week, catching nine passes for 180 yards on 12 targets. He gets a matchup against the Denver Broncos, who have struggled at times against tight ends. Cook could see a slight downtick in targets as the season progresses, but he could potentially see double digit targets once again. He's a cheap option with a high floor and even higher ceiling.

 

FanPicks Defense - Week 2 DFS Pick

Los Angeles Chargers - at BUF ($3,400)

The Buffalo Bills feature the worst offense in the NFL. They scored only three points in the opener, and they will now get a matchup against the Los Angeles Chargers, who feature arguably the best secondary in the NFL. Josh Allen will draw the start, and he's a bit known for being careless with the football. The Bills own an implied total of only 17.5 points, which is the second lowest on the slate. Los Angeles is a safe play at defense.

 

More Weekly DFS Analysis




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REAL-TIME FANTASY NEWS

Mikael Granlund

Returning From 10-Game Absence Friday
P.J. Washington

Won't Suit Up Friday Night
John Carlson

Misses Second Consecutive Game Friday
Rome Odunze

has Fractured Foot, Labeled Week-to-Week
Brandon Miller

Trending Toward A Return To The Court
Paul George

Avoids Injury Report On Friday
Alperen Sengün

Alperen Sengun Added To Injury Report With An Illness
Joel Embiid

Sitting Out Game 2 of a Back-To-Back
Evan Mobley

Questionable For Friday Night's Game
LeBron James

Lebron James, Luka Doncic Missing Friday's Game
Sauce Gardner

Ruled Out for Sunday
Luke Kornet

To Be Sidelined In Cleveland
Norman Powell

Good To Go Versus Orlando
Petr Yan

Looks To Reclaim Bantamweight Belt
Merab Dvalishvili

Set For His Fourth Title Defense
Joshua Van

Can Become The New Flyweight Champion
Aaron Jones Sr.

Cleared to Play in Week 14
Chris Olave

Listed as Questionable for Week 14
Jaylen Brown

Off the Injury Report
Alexandre Pantoja

Set For Fifth Title Defense At UFC 323
Paolo Banchero

Returning on Friday Night
Tatsuro Taira

Looks To Win Back-To-Back Fights
Alvin Kamara

Ruled Out for Sunday
Brandon Moreno

Searches For His Third Win In A Row
Rome Odunze

Ruled Out for Week 14
Payton Talbott

A Favorite At UFC 323
Henry Cejudo

Set For His Retirement Fight
Drake London

Ruled Out vs Seattle
Jan Blachowicz

Set To Open Up UFC 323 Main Card
Lamar Jackson

Will Play on Sunday
Bogdan Guskov

Looks To Extend His Win Streak
CFB

Emmett Johnson Leaving Nebraska for 2026 NFL Draft
Dalton Kincaid

to be Questionable for Week 14
Tee Higgins

Clears Concussion Protocol, is a Full-Go for Sunday
CFB

Jam Miller Unlikely to Play in SEC Title Game
CFB

Penn State Expected to Hire Matt Campbell from Iowa State
Mike Evans

Not Quite Ready to Return This Week
Jayden Daniels

Will Start Against Vikings
Lamar Jackson

Returns to Practice, on Track to Play on Sunday
Kyler Murray

Won't Return This Year, Cardinals Non-Committal on his Future
Trey Benson

Out in Week 14; Could he Miss the Rest of the Season?
Marvin Harrison Jr.

Ruled Out for Sunday's Game
CeeDee Lamb

in the League's Concussion Protocol
Brian Branch

Out with Torn Achilles
Daniel Gafford

Uncertain For Friday's Game
Darius Garland

Ruled Out For Friday Against Spurs
Kristaps Porzingis

Tagged as Questionable Against Nuggets
Jalen Johnson

Could Miss Second Straight Game
LaMelo Ball

Probable To Play Through Wrist Sprain Friday
Detroit Lions

Brian Branch Feared to Have Suffered an Achilles Injury
Tyler Herro

Uncertain For Magic Matchup
CFB

Arkansas Targeting Ron Roberts for Defensive Coordinator Job
Jayden Daniels

Tracking Towards a Week 14 Return
Justin Herbert

Trending in the Right Direction to Play Monday Night
Mathew Barzal

Leads Islanders Past Avalanche
Elias Lindholm

Posts Hat Trick of Assists Thursday
Leon Draisaitl

Notches Season-High Four Points in Thursday's Win
Connor McDavid

Nets 13th Career Hat Trick
Teuvo Teravainen

Expected to Be Fine After Thursday's Exit
Shane Pinto

Exits Loss With Injury
Joseph Woll

Sustains Lower-Body Injury Thursday
Jhostynxon Garcia

Pirates Acquire Jhostynxon Garcia From Red Sox
Draymond Green

Won't Return on Thursday Night
Cody Bellinger

Yankees Pushing Hard to Re-Sign Cody Bellinger
CFB

Penn State Eyeing Iowa State Coach Matt Campbell For Coaching Vacancy
Alex Bregman

Cubs Have Renewed Interest in Alex Bregman
Quinten Post

Set to Suit Up Versus Philadelphia
Joel Embiid

Back on Thursday Night
Al Horford

Available on Thursday
Kirill Marchenko

Returns From Four-Game Absence
Carter Verhaeghe

Ready to Return Thursday
Scott Wedgewood

Skips Thursday's Game
Danila Yurov

Misses Second Straight Game
CFB

Billy Napier Finalizing Deal to Become James Madison's New Head Coach
Andrei Vasilevskiy

Unavailable Thursday
CFB

Buster Faulkner Set to Become Florida's New Offensive Coordinator
David Pastrnak

Still Out Thursday
Ryan McDonagh

Lightning Sign Ryan McDonagh to Three-Year Extension
CFB

Joe Sloan Expected to be Kentucky's New Offensive Coordinator
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Lane Kiffin Working to Keep Defensive Coordinator Blake Baker at LSU
CFB

Brian Daboll a Candidate for Penn State Head-Coaching Job?
Karel Vejmelka

Records Impressive Shutout
JJ Peterka

Rocks Ducks With Four-Point Effort
Cole Caufield

Extends Point Streak With Power-Play Assist
Matvei Michkov

Delivers Two Assists Wednesday
Jake Oettinger

Grabs Fourth Consecutive Victory With Shutout
Kyle Tucker

Visits With Blue Jays
Emilio Pagán

Reds Bring Back Closer Emilio Pagan on Two-Year Deal
Cedric Mullins

Rays Agree on One-Year Deal
Freddy Peralta

Brewers Considering Trading Freddy Peralta
Kyle Schwarber

Reds Serious About Adding Kyle Schwarber in Free Agency?
CFB

Brent Key Signing Five-Year Deal to Remain at Georgia Tech
CFB

Brian Hartline Expected to Land USF Head-Coaching Job
CFB

Collin Klein Expected to be Top Target for Kansas State if Head-Coach Job Opens
CFB

Chris Klieman Considering Stepping Down at Kansas State
CFB

D.J. Durkin Staying at Auburn Under Alex Golesh
CFB

Charlie Weis Jr. Permitted to Coach Ole Miss Offense in College Football Playoff
CFB

Five-Star Quarterback Jared Curtis Flips Commitment From Georgia to Vanderbilt
CFB

Florida Hiring Brad White as Defensive Coordinator
Kyle Schwarber

Giants Have Checked in on Kyle Schwarber
Willson Contreras

Willing to Waive his Full No-Trade Clause?
Edwin Díaz

Mets Still Interested in Re-Signing Edwin Diaz
Devin Williams

Agrees to Three-Year Deal With Mets
Cole Ragans

Red Sox Targeting Cole Ragans in a Trade?
CFB

Kentucky Hires Oregon Offensive Coordinator Will Stein As Head Coach
CFB

Kalani Sitake the Top Target for Penn State Coaching Job
CFB

Josh Heupel Says He's Not a Candidate for Penn State Head Coach Job
Zack Wheeler

Likely to Return in May

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