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FanDuel NFL DFS Lineup Picks (Week 15): Daily Fantasy Football Advice

Tom Vecchio highlights the top FanDuel NFL DFS lineup picks for Week 15, and a couple of sleepers to consider while building daily rosters.

RotoBallers, welcome to Week 15 of the daily fantasy football season. In this column, you will find my recommended FanDuel DFS Lineup Picks to target for Week 15 of the NFL season. You can also click here to find more DFS analysis articles and tools.

The goal is to identify players to start on FanDuel this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the FanDuel price.

Let's find some DFS lineup sleepers, and win on FanDuel. Good luck in Week 15! Find me @DFS_Tom if you have any questions.

Be sure to check all of our fantasy football rankings for 2025:

 

FanDuel Quarterbacks - Week 15 DFS Picks

Tom Brady - QB, NE @ PIT (FD - $7,900)

Brady is often a quarterback who goes overlooked on most weeks due to his higher price, but this is the spot you should be willing to roster him. He has amazing success against the Steelers, with multiple touchdowns in six of his last seven regular season games against them. Yes, there are obviously some differences in the teams, but he has always seemingly had their number and now with the Patriots needing to pick up a win after last week, he will certainly reach that production again. The Steelers come in with the 21st DVOA versus the pass this season and have given up 24 points or more in three straight games.

Kirk Cousins - QB, MIN vs MIA (FD - $7,800)

Cousins is coming off of two bad games, there is really no other way to put it. He has under 210 yards in each of these last two games and only one touchdown, along with two interceptions. Those are some really rough to look at and if most people are box score watching, they won't be willing to roster him, but you should be looking to him in tournaments this week. He is up against the Dolphins who come in with the 26th DVOA versus the pass and have allowed multiple touchdowns in four straight games. The Vikings need to win here to make a push towards the playoffs and this is an easier game to do so.

 

FanDuel Running Backs - Week 15 DFS Picks

Joe Mixon - RB, CIN vs OAK (FD - $7,800)

Mixon and the Bengals may not be the best offense in the league, but they are up against the Raiders, who are one of the worst defenses so a spot for him to thrive. He comes in with 21 or more touches in two of his last three games, a level of involvement in the offense which should continue with A.J. Green out for the year. The Raiders come in with the 32nd DVOA versus the pass, the 27th DVOA versus the rush and the 21st DVOA versus running backs in the passing game. All of this adds up for Mixon to be in the ideal spot this week and continue posting big numbers against this Raiders defense.

Tarik Cohen  - RB, CHI vs GB (FD - $6,800)

Cohen makes a nice GPP play this week and comes in with a very favorable matchup versus the Packers, who are 27th DVOA against running backs in the passing game. Cohen has five or more targets in four of his last five games and while FanDuel isn't a full PPR site, he can bring solid upside with his big play ability. This game has a modest over-under set at 45 points, but we've seen these divisional games get a bit out of hand and post plenty of points.

 

FanDuel Wide Receivers - Week 15 DFS Picks

T.Y. Hilton - WR, IND vs DAL (FD - $7,900)

Hilton has some solid home v road splits, so you want to be rostering him when he is at home, as he is this week. He comes in with 10 or more targets in each of his last three games, with over 125 yards in three of his last four and two touchdowns in that span. He is posting big number nearly every week and even with this being a bit of a tougher matchup versus the Cowboys who are 12 DVOA against the pass, he still brings plenty of tournament upside.

Larry Fitzgerald - WR, ARI @ ATL (FD - $6,000)

Fitzgerald has six or more targets in six of his last eight games and is in a fantastic spot this week against the Falcons, who are giving up the ninth most fantasy points to slot receivers this season. It should be noted that the Cardinals come in with an implied team total set at 17.8, which is the third lowest in the entire week. It really comes down to this, the Cardinals don't have a good offense, but they have a fantastic matchup this week, use Fitzy sparing this week.

 

FanDuel Tight End - Week 15 DFS Pick

Cameron Brate - TE, TB @ BAL (FD - $5,400)

Brate has been super popular over the past few weeks since OJ Howard is done for the year with an injury and Brate is making the most of this opportunity. He has three touchdowns in his last three weeks and despite this being a tougher matchup on the surface, he actually has some nice upside. The Ravens are 4th DVOA versus the pass, but they are 26th DVOA versus tight ends specifically. A slight opening for him to continue reaching the end zone.

 

FanDuel Defense - Week 15 DFS Pick

Atlanta Falcons vs Arizona Cardinals (FD - $4,000)

The Falcons aren't a team you normally look towards for solid defense, but they are at home against Josh Rosen and the Cardinals and are actually in play this week. Rosen has thrown an interception in seven of his last eight games, giving the Falcons a bit of upside to turn that into a touchdown this week. Arizona comes in with and implied team total set at 17, which is one of the lowest ones on the slate.

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