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FanDuel NFL DFS Lineup Picks (Week 15): Daily Fantasy Football Advice

Tom Vecchio highlights the top FanDuel NFL DFS lineup picks for Week 15, and a couple of sleepers to consider while building daily rosters.

RotoBallers, welcome to Week 15 of the daily fantasy football season. In this column, you will find my recommended FanDuel DFS Lineup Picks to target for Week 15 of the NFL season. You can also click here to find more DFS analysis articles and tools.

The goal is to identify players to start on FanDuel this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the FanDuel price.

Let's find some DFS lineup sleepers, and win on FanDuel. Good luck in Week 15! Find me @DFS_Tom if you have any questions.

Be sure to check all of our fantasy football rankings for 2025:

 

FanDuel Quarterbacks - Week 15 DFS Picks

Tom Brady - QB, NE @ PIT (FD - $7,900)

Brady is often a quarterback who goes overlooked on most weeks due to his higher price, but this is the spot you should be willing to roster him. He has amazing success against the Steelers, with multiple touchdowns in six of his last seven regular season games against them. Yes, there are obviously some differences in the teams, but he has always seemingly had their number and now with the Patriots needing to pick up a win after last week, he will certainly reach that production again. The Steelers come in with the 21st DVOA versus the pass this season and have given up 24 points or more in three straight games.

Kirk Cousins - QB, MIN vs MIA (FD - $7,800)

Cousins is coming off of two bad games, there is really no other way to put it. He has under 210 yards in each of these last two games and only one touchdown, along with two interceptions. Those are some really rough to look at and if most people are box score watching, they won't be willing to roster him, but you should be looking to him in tournaments this week. He is up against the Dolphins who come in with the 26th DVOA versus the pass and have allowed multiple touchdowns in four straight games. The Vikings need to win here to make a push towards the playoffs and this is an easier game to do so.

 

FanDuel Running Backs - Week 15 DFS Picks

Joe Mixon - RB, CIN vs OAK (FD - $7,800)

Mixon and the Bengals may not be the best offense in the league, but they are up against the Raiders, who are one of the worst defenses so a spot for him to thrive. He comes in with 21 or more touches in two of his last three games, a level of involvement in the offense which should continue with A.J. Green out for the year. The Raiders come in with the 32nd DVOA versus the pass, the 27th DVOA versus the rush and the 21st DVOA versus running backs in the passing game. All of this adds up for Mixon to be in the ideal spot this week and continue posting big numbers against this Raiders defense.

Tarik Cohen  - RB, CHI vs GB (FD - $6,800)

Cohen makes a nice GPP play this week and comes in with a very favorable matchup versus the Packers, who are 27th DVOA against running backs in the passing game. Cohen has five or more targets in four of his last five games and while FanDuel isn't a full PPR site, he can bring solid upside with his big play ability. This game has a modest over-under set at 45 points, but we've seen these divisional games get a bit out of hand and post plenty of points.

 

FanDuel Wide Receivers - Week 15 DFS Picks

T.Y. Hilton - WR, IND vs DAL (FD - $7,900)

Hilton has some solid home v road splits, so you want to be rostering him when he is at home, as he is this week. He comes in with 10 or more targets in each of his last three games, with over 125 yards in three of his last four and two touchdowns in that span. He is posting big number nearly every week and even with this being a bit of a tougher matchup versus the Cowboys who are 12 DVOA against the pass, he still brings plenty of tournament upside.

Larry Fitzgerald - WR, ARI @ ATL (FD - $6,000)

Fitzgerald has six or more targets in six of his last eight games and is in a fantastic spot this week against the Falcons, who are giving up the ninth most fantasy points to slot receivers this season. It should be noted that the Cardinals come in with an implied team total set at 17.8, which is the third lowest in the entire week. It really comes down to this, the Cardinals don't have a good offense, but they have a fantastic matchup this week, use Fitzy sparing this week.

 

FanDuel Tight End - Week 15 DFS Pick

Cameron Brate - TE, TB @ BAL (FD - $5,400)

Brate has been super popular over the past few weeks since OJ Howard is done for the year with an injury and Brate is making the most of this opportunity. He has three touchdowns in his last three weeks and despite this being a tougher matchup on the surface, he actually has some nice upside. The Ravens are 4th DVOA versus the pass, but they are 26th DVOA versus tight ends specifically. A slight opening for him to continue reaching the end zone.

 

FanDuel Defense - Week 15 DFS Pick

Atlanta Falcons vs Arizona Cardinals (FD - $4,000)

The Falcons aren't a team you normally look towards for solid defense, but they are at home against Josh Rosen and the Cardinals and are actually in play this week. Rosen has thrown an interception in seven of his last eight games, giving the Falcons a bit of upside to turn that into a touchdown this week. Arizona comes in with and implied team total set at 17, which is one of the lowest ones on the slate.

More Weekly DFS Analysis




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REAL-TIME FANTASY NEWS

Daniel Jones

Undergoes Surgery, Expected to be Ready for Training Camp
Brandon Aiyuk

Placed on Reserve/Left Squad List, Out for the Season
Christian McCaffrey

Expected to Play in Week 15
Haydn Fleury

Cleared to Play
Simon Nemec

to Miss "Some Time"
Jake Evans

Back for Canadiens Saturday
Ilya Lyubushkin

Returns to Stars Lineup Saturday
Roope Hintz

Good to Go Saturday
Charlie Lindgren

Activated From Injured Reserve
Oliver Ekman-Larsson

Available Against Oilers
William Nylander

a Game-Time Decision Saturday
Brandon Aiyuk

49ers' "Optimism Has Run Out" on Brandon Aiyuk
Philip Rivers

Will Start on Sunday Against the Seahawks
Jorge Polanco

Agrees to Two-Year Deal With Mets
De'Von Achane

Expected to Play Monday Night
Rome Odunze

Bears Optimistic Rome Odunze Will Play in Week 15
CFB

LaNorris Sellers to Return to South Carolina in 2026
Cason Wallace

Off Injury Report Saturday
Keyonte George

Erupts for Career-High 39 Points Against Memphis
Bones Hyland

Exits Early With Knee Contusion
Isaiah Joe

To Miss Fourth Straight Game
Isaiah Hartenstein

Removed From Injury Report
Austin Reaves

To Be Re-Evaluated In One Week With Calf Strain
Logan O'Connor

Still Not Ready for Season Debut
Lukas Dostal

Activated From Injured Reserve
NJ

Arseni Gritsyuk Ruled Out for Weekend's Action
Connor Bedard

Ruled Out for Saturday
Zeev Buium

Canucks Acquire Zeev Buium From Wild
Marco Rossi

Moves to Vancouver
Quinn Hughes

Traded to WIld
Joel Embiid

Available Against Indiana
Ja Morant

Back on Friday Night
Rickard Rakell

Available Saturday
Tre Jones

is Returning on Friday
Coby White

Cleared for Action Versus Hornets
Jake Ferguson

Listed as Questionable for Week 15
Bo Horvat

Ruled Out for Saturday
Tre Johnson

to be Limited in Return on Friday
Andrei Vasilevskiy

Could Return Monday
Geno Smith

Officially Ruled Out for Week 15
Victor Hedman

to Be Out Until February
Kenny Pickett

to Start in Week 15 Against Eagles
Moussa Diabaté

Moussa Diabate Available on Friday
Jared McCann

to Miss Three Weeks With Lower-Body Injury
Tyrese Maxey

Under the Weather on Friday
Josh Jacobs

Officially Questionable to Face the Broncos
Victor Wembanyama

Expected to Return on Saturday
Stuart Skinner

Shipped to Pittsburgh
Anthony Edwards

Sidelined on Friday Evening
Deebo Samuel Sr.

Questionable for Week 15
CFB

Washington State Expected to Hire Kirby Moore as Next Head Coach
CFB

Kyle Whittingham Stepping Down as Utah Head Coach
T.J. Watt

Officially Ruled Out for Monday Night
Manel Kape

Set For UFC Vegas 112 Main Event
Davante Adams

to be Questionable, Expected to Play on Sunday
Brandon Royval

An Underdog At UFC Vegas 112
Rome Odunze

Questionable for Sunday
Kevin Vallejos

Set For His Third UFC Fight
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Ruled Out for Sunday
Giga Chikadze

In Dire Need Of Victory
Cesar Almeida

Set To Welcome Cezary Oleksiejczuk To The UFC
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Set To Make His UFC Debut
Jayden Daniels

Not Cleared for Contact
T.J. Watt

Undergoes Surgery for Collapsed Lung
Maikel Garcia

Royals Agree on Five-Year Extension
Melquizael Costa

Looks To Extend His Win Streak
Morgan Charrière

Morgan Charriere Looks to Win Second Consecutive Fights
Marcus Buchecha

Looks To Bounce Back
Kennedy Nzechukwu

A Favorite At UFC Vegas 112
King Green

Returns At UFC Vegas 112
Lance Gibson jr

Lance Gibson Jr. Set To Open Up UFC Vegas 112 Main Card
Jake Ferguson

on Track to Play in Week 15
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Sherrone Moore Charged with Home Invasion, Among Other Charges
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Cleared for Contact
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Ruled Out Against Ravens
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Still Unlikely to Play Friday
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Expected To Play Friday Vs. Hornets
Ayo Dosunmu

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Freddie Kitchens Fired from North Carolina Coaching Staff
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Bryce Underwood Could Leave Michigan Without Buyout
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Padres Not Considering Trading Fernando Tatis Jr.
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Tigers Engaged in "Serious Talks" Around Trading Tarik Skubal at the Winter Meetings
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Chris Brazzell II Declaring for NFL Draft
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Fernando Mendoza Named AP College Football Player of the Year
Raisel Iglesias

to Remain the Braves Closer
Robert Suarez

Agrees on Three-Year Deal With Braves
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Sherrone Moore Remains in Police Custody
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Joe Klanderman Joining Baylor Coaching Staff
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Kentucky Hiring Jay Bateman as Next Defensive Coordinator
Si Woo Kim

Closes 2025 With Strong Finish Among Putting Woes
Akshay Bhatia

Looks to Rebound in 2026 After Down Year Off the Tee
Brian Harman

2025 Season a Step Back Despite Spring Win
Sam Burns

' Elite Putting Headlines a Solid 2025 Season
Sepp Straka

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Robert MacIntyre

Closes Out a Steady 2025 Campaign
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Chip Kelly Interviews for Georgia Tech Offensive Coordinator Job
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Louisville Receiver Chris Bell has a Torn ACL
Min Woo Lee

Breaks Through to Win in Texas This Year
PGA

Alex Noren Wins Twice on European Tour This Year
Wyndham Clark

has Up-and-Down 2025 Golf Season
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Michigan Fires Head Coach Sherrone Moore
Corey Conners

Comes Close to Winning Again in Very Good 2025
Justin Rose

Turns Back the Clock in 2025
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Jim Knowles Expected to be Hired as Tennessee's Defensive Coordinator
Harris English

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CFB

Defensive Coordinator Jim Knowles Not Being Retained at Penn State
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Indiana's Stephen Daley Done for Season After Post-Game Injury
Pete Alonso

Orioles Finalizing Five-Year Deal
Kyle Finnegan

Tigers, Kyle Finnegan Agree on Two-Year Deal
Bo Bichette

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Phillies Extend Manager Rob Thomson Through 2027 Season
Michael King

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Ronald Acuña Jr.

Ronald Acuna Jr. Could Move Back to Leadoff Spot
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Florida, Wisconsin Among Suitors for QB Transfer Kenny Minchey
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Bryan Harsin, Justin Wilcox Candidates for Washington State Head Coach Job?
Edwin Díaz

Edwin Diaz Agrees to Deal With the Dodgers
Kyle Schwarber

Returning to Phillies on Five-Year Deal
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Ole Miss Hiring John David Baker as Offensive Coordinator
CFB

Ty Howle the Top Target for Virginia Tech Offensive Coordinator Job
Shohei Ohtani

to be Used More as Traditional Starting Pitcher Next Year
Yordan Alvarez

to Become Full-Time DH in 2026?
Mason Miller

Padres Plan to Keep Mason Miller in the Bullpen
Ranger Suárez

Orioles Interested in Signing Ranger Suarez
Anthony Volpe

Yankees Don't Expect Anthony Volpe to be Ready in April
Gerrit Cole

Targeting a Return in May/June
Rory McIlroy

Ends 2025 as the Year's Most Unburdened Player
Aaron Rai

Needs to Figure Out Putting Woes This Offseason
Jordan Spieth

Plays Better on Paper in 2025 Than Results Show
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Chris Gotterup Needs to Find Better Touch and Consistency This Offseason
Hideki Matsuyama

Ends 2025 Season With a Bookend Victory
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