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FanDuel Lineup Picks (Week 10) - NFL DFS Advice

FanDuel NFL DFS lineup picks and start 'em, sit' em for Week 10. Daily fantasy football sleepers and lineups cheat sheet for FanDuel DFS GPPs and tournaments.

Welcome to RotoBaller's daily fantasy football FanDuel lineup picks for Week 10 of the NFL season. In this article I will be taking you through the best FanDuel DFS plays of the week for this upcoming Sunday.

These FanDuel lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more.

Good luck with your FanDuel DFS lineups!

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FanDuel Quarterbacks - Week 10 DFS Picks

Ryan Fitzpatrick (vs. NYJ, $6,100)

Ryan Fitzpatrick will be behind center for the Buccaneers this week and for the foreseeable future. The combination of price and matchup (plus a little narrative) make it difficult to pass in this spot despite the fact that Mike Evans won’t be on the field this week. The Jets are ranked 21st in pass DVOA and the price will allow spending up at other spots on the slate.

Matthew Stafford (vs. CLE, $8,200)

If you’re feeling a safer option than Fitzpatrick this week, Stafford is the quarterback to turn to. Stafford has been good lately, passing for multiple touchdowns in two of his past three games and over 300 yards in all three. He should be able to do each of those things against a hapless Browns pass defense that ranks 28th in pass DVOA for the season. The only risk for Stafford is that the Lions pull ahead quickly without those scores coming through the air, but with the ineptitude of their ground game that seems unlikely.

 

FanDuel Running Backs - Week 10 DFS Picks

Carlos Hyde (vs. NYG, $6,700)

Carlos Hyde hasn’t been anything special on the ground this season which is obviously not a great statement in reference to a running back. On the other hand, he has been very involved in the pass game which has kept his floor at a safe level. When the 49ers have lost by 10 points or less this season, Hyde has seen an average of 23 touches per game. The Giants are just as inept as the 49ers, if not more, so this should be a close game between two bad teams and allow Hyde to see a healthy dose of touches.

Bilal Powell (@TB, $6,000)

With Matt Forte officially out this week, we can look to Powell as a bargain running back that paves the way to Antonio Brown, LeVeon Bell, or Gronk. While the narrative has been that the Jets rushing attack has been an unreliable mess in terms of workload, the absence of Forte should open sufficient volume for Powell to take advantage of. The Bucs are far from tough on opposing running backs, allowing big games to Adrian Peterson, LeSean McCoy, and the Saints running back committee of late, opening up some more nice value at the running back position.

 

FanDuel Wide Receivers - Week 10 DFS Picks

A.J. Green (@TEN, $7,900) 

A.J. Green has been a story this week, but not because of his play. He should be motivated to perform as a result and he’s in a decent spot to do so. Though Tennessee has shown improvement on defense, most of that improvement has come against opposing rushing attacks. If the Bengals are smart, that’s a big if, they will pepper A.J. Green with targets as has a six-inch height advantage over otherwise impressive rookie Adoree’ Jackson.

Marvin Jones (vs. CLE, $6,400)

Golden Tate has been a reliable option this season, but the price disparity between he and Marvin Jones on FanDuel doesn’t make much sense. Over the past three games, in which Matt Stafford has gotten on track, Jones has put up 18.6, 15.8, and 26.2 FD points respectively. In an A+ matchup there’s no reason to go away from Jones.

 

FanDuel Tight End - Week 10 DFS Pick

Rob Gronkowski (@DEN, $8,100) 

Gronk is a relatively easy choice this week, assuming the ability or desire to pay up at the position. The Broncos still can’t cover opposing tight ends, as they have allowed 14.47 FD points per game to them on the season. Coming off of a bye week, the Patriots will be prepared to take advantage of that huge edge making Gronk worth the premium.

 

FanDuel Defense - Week 10 DFS Pick

Chicago Bears (vs. CIN, $4,300)

The Bears have been a respectable defense all season, especially at home, and the Packers offense has been non-existent since the loss of Aaron Rodgers. It comes as little surprise that they have an implied total of just 16.25 The Bears will be the chalk defense of the week, but at this price point there is good reason why.

 

More Week 10 DFS Analysis

 

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REAL-TIME FANTASY NEWS

P.J. Washington

is Ruled Out for Thursday's Contest
Jaime Jaquez Jr.

is Returning on Thursday
Daniel Jones

Colts Plan to Re-Sign Daniel Jones
Darius Garland

to Play on Thursday
Anthony Edwards

Active Thursday
Coby White

to Play with Minutes Limit on Thursday
Ace Bailey

Sidelined on Thursday
Kevin Huerter

Won't Play on Thursday
Andrew Nembhard

Won't Play on Thursday
Brandon Miller

is Cleared for Thursday's Game
LaMelo Ball

Upgraded to Available on Thursday
Kevin Love

Available For Thursday
Kawhi Leonard

Suffers Ankle Injury, Considered Questionable for Friday
Jamie Drysdale

Unavailable Against Maple Leafs
Bobby Brink

Sits Out Thursday
Simon Nemec

Back for Devils Thursday
Jusuf Nurkić

Jusuf Nurkic Questionable For Thursday Against Mavs
Troy Terry

Misses Thursday's Game
Alexis Lafrenière

Alexis Lafreniere Good to Go Against Sabres
Brad Marchand

Out Thursday
Ace Bailey

Considered Questionable Versus Dallas
Evgeni Malkin

Set to Return Thursday
Anthony Edwards

Questionable for Thursday
Davante Adams

Off the Injury Report, Will Play Against Carolina
Bo Bichette

Phillies to Meet With Bo Bichette
Rome Odunze

Will Return for Wild-Card Game on Saturday
CFB

DJ Lagway Commits to Baylor
Miami Dolphins

Dolphins Fire Head Coach Mike McDaniel
Matvei Michkov

Expected to Play Thursday
Alex Lyon

to Miss at Least One More Week
Mason Marchment

Placed on Injured Reserve, Out Week-to-Week
Alexis Lafrenière

Alexis Lafreniere Battling Illness, Iffy for Thursday
J.T. Miller

Likely to Return Thursday
Adam Henrique

Out Through Olympic Break
Dean Wade

Ruled Out Thursday
Brandon Williams

Questionable for Thursday
P.J. Washington

Doubtful Thursday
Jaime Jaquez Jr.

Questionable Thursday
Donovan Mitchell

Available Thursday
Corey Kispert

Hawks Land Corey Kispert
Sam LaPorta

Plans to be Back for Training Camp
Owen Caissie

Shipped to Miami as Centerpiece of Trade
Edward Cabrera

Cubs Officially Acquire Edward Cabrera From Marlins
Nathan Walker

Ready to End 16-Game Absence
Rutger McGroarty

Out Indefinitely With Concussion
Kevin Stenlund

a Game-Time Call Wednesday
Ty Dellandrea

Ruled Out Wednesday
Adam Erne

Misses Wednesday's Action
Tom Wilson

Aliaksei Protas Won't Play Wednesday
Anze Kopitar

Out Wednesday
Rome Odunze

Plans to Play on Saturday
Edward Cabrera

Cubs Finalizing Deal to Acquire Edward Cabrera From Marlins
New York Giants

Giants "All-In" on Hiring John Harbaugh
CFB

Jackson Arnold Signs with UNLV
CFB

Sam Leavitt Scheduled to Visit Tennessee
Devon Toews

to Miss at Least Two Weeks
New York Giants

John Harbaugh Expected to be Favorite to Become New Giants Head Coach
Baltimore Ravens

John Harbaugh Won't Return as Ravens Head Coach
Bo Bichette

Unlikely to Return to Toronto?
Jordan Love

Ready to Start in Wild-Card Game Against Bears
CFB

Jadan Baugh Staying with Florida for Junior Season
Washington Commanders

Commanders "Mutually" Parting Ways With OC Kliff Kingsbury
CFB

Byrum Brown Officially Commits to Auburn
CFB

Austin Simmons Signing with Missouri
CFB

Ty Simpson Undecided on 2026 Plans
CFB

Quarterback AJ Hill Following Ryan Silverfield to Arkansas
Atlanta Falcons

Falcons Have Requested an Interview With Klint Kubiak
Deshaun Watson

Browns Expect Deshaun Watson to be on the Team Next Year
Wan'Dale Robinson

Dealing With Fractured Ribs
Cam Skattebo

Hopes to be Back by Training Camp
Cameron Ward

Won't Need Surgery on his Shoulder
Davante Adams

Rams Expect Davante Adams to Return in Wild-Card Round
Arizona Cardinals

Cardinals Fire Head Coach Jonathan Gannon
Las Vegas Raiders

Raiders Fire Head Coach Pete Carroll
Malik Nabers

Unsure if He Will Be Ready for Week 1 of 2026 Season
CFB

Trinidad Chambliss Will Return to Ole Miss If Granted Sixth Year of Eligibility
Cincinnati Bengals

Zac Taylor Will Return as Bengals Head Coach in 2026
Bo Bichette

Phillies Have Interest in Bo Bichette
Kansas City Royals

Matt Quatraro Signs Three-Year Extension With Royals
CFB

Transfer QB Billy Edwards Commits to North Carolina
CFB

Sam Leavitt Visiting Texas Tech on Saturday
CFB

DJ Lagway Expected To Visit Florida State
Kyle Tucker

Blue Jays "Remain the Favorite" to Sign Kyle Tucker

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