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FanDuel Lineup Picks (Week 10) - NFL DFS Advice

FanDuel NFL DFS lineup picks and start 'em, sit' em for Week 10. Daily fantasy football sleepers and lineups cheat sheet for FanDuel DFS GPPs and tournaments.

Welcome to RotoBaller's daily fantasy football FanDuel lineup picks for Week 10 of the NFL season. In this article I will be taking you through the best FanDuel DFS plays of the week for this upcoming Sunday.

These FanDuel lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more.

Good luck with your FanDuel DFS lineups!

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FanDuel Quarterbacks - Week 10 DFS Picks

Ryan Fitzpatrick (vs. NYJ, $6,100)

Ryan Fitzpatrick will be behind center for the Buccaneers this week and for the foreseeable future. The combination of price and matchup (plus a little narrative) make it difficult to pass in this spot despite the fact that Mike Evans won’t be on the field this week. The Jets are ranked 21st in pass DVOA and the price will allow spending up at other spots on the slate.

Matthew Stafford (vs. CLE, $8,200)

If you’re feeling a safer option than Fitzpatrick this week, Stafford is the quarterback to turn to. Stafford has been good lately, passing for multiple touchdowns in two of his past three games and over 300 yards in all three. He should be able to do each of those things against a hapless Browns pass defense that ranks 28th in pass DVOA for the season. The only risk for Stafford is that the Lions pull ahead quickly without those scores coming through the air, but with the ineptitude of their ground game that seems unlikely.

 

FanDuel Running Backs - Week 10 DFS Picks

Carlos Hyde (vs. NYG, $6,700)

Carlos Hyde hasn’t been anything special on the ground this season which is obviously not a great statement in reference to a running back. On the other hand, he has been very involved in the pass game which has kept his floor at a safe level. When the 49ers have lost by 10 points or less this season, Hyde has seen an average of 23 touches per game. The Giants are just as inept as the 49ers, if not more, so this should be a close game between two bad teams and allow Hyde to see a healthy dose of touches.

Bilal Powell (@TB, $6,000)

With Matt Forte officially out this week, we can look to Powell as a bargain running back that paves the way to Antonio Brown, LeVeon Bell, or Gronk. While the narrative has been that the Jets rushing attack has been an unreliable mess in terms of workload, the absence of Forte should open sufficient volume for Powell to take advantage of. The Bucs are far from tough on opposing running backs, allowing big games to Adrian Peterson, LeSean McCoy, and the Saints running back committee of late, opening up some more nice value at the running back position.

 

FanDuel Wide Receivers - Week 10 DFS Picks

A.J. Green (@TEN, $7,900) 

A.J. Green has been a story this week, but not because of his play. He should be motivated to perform as a result and he’s in a decent spot to do so. Though Tennessee has shown improvement on defense, most of that improvement has come against opposing rushing attacks. If the Bengals are smart, that’s a big if, they will pepper A.J. Green with targets as has a six-inch height advantage over otherwise impressive rookie Adoree’ Jackson.

Marvin Jones (vs. CLE, $6,400)

Golden Tate has been a reliable option this season, but the price disparity between he and Marvin Jones on FanDuel doesn’t make much sense. Over the past three games, in which Matt Stafford has gotten on track, Jones has put up 18.6, 15.8, and 26.2 FD points respectively. In an A+ matchup there’s no reason to go away from Jones.

 

FanDuel Tight End - Week 10 DFS Pick

Rob Gronkowski (@DEN, $8,100) 

Gronk is a relatively easy choice this week, assuming the ability or desire to pay up at the position. The Broncos still can’t cover opposing tight ends, as they have allowed 14.47 FD points per game to them on the season. Coming off of a bye week, the Patriots will be prepared to take advantage of that huge edge making Gronk worth the premium.

 

FanDuel Defense - Week 10 DFS Pick

Chicago Bears (vs. CIN, $4,300)

The Bears have been a respectable defense all season, especially at home, and the Packers offense has been non-existent since the loss of Aaron Rodgers. It comes as little surprise that they have an implied total of just 16.25 The Bears will be the chalk defense of the week, but at this price point there is good reason why.

 

More Week 10 DFS Analysis

 

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REAL-TIME FANTASY NEWS

Lamar Jackson

Questionable to Return in Week 16 with Back Injury
Donovan Mitchell

Likely to Return on Monday Night
Willson Contreras

Shipped to the Red Sox
Patrick Kane

to Miss Fifth Consecutive Game
Tyson Kozak

Misses Second Consecutive Game
Jakob Poeltl

Back in the Lineup on Sunday Night
Jack Roslovic

Ready to Return Sunday
Alexandre Sarr

Ruled Out Against San Antonio
NJ

Arseni Gritsyuk Back in Devils Lineup Sunday
Marvin Bagley III

Ruled Out Against San Antonio
Timo Meier

Available Sunday
Davion Mitchell

Available on Sunday Night
Jack Hughes

Returns From 18-Game Absence Sunday
Andrew Wiggins

Cleared to Play on Sunday Night
J.T. Miller

Out Week-to-Week
Quinshon Judkins

Done for the Season with Broken Leg
Gardner Minshew

Likely Tore His ACL on Sunday
Nick Chubb

Officially Active Against Raiders in Week 16
Gardner Minshew

Won't Return in Week 16
Woody Marks

Officially Inactive for Week 16
Quinshon Judkins

Carted Off in Week 16, Ruled Out with Apparent Leg Injury
Tua Tagovailoa

Dolphins Hope to Trade Tua Tagovailoa in the Offseason
Woody Marks

Not Expected to Play in Week 16
Washington Commanders

Commanders to Retain Dan Quinn, Fire Joe Whitt?
New York Giants

Marcus Freeman is a Top Candidate in Giants' Head Coaching Search
Cincinnati Bengals

Zac Taylor Expected to Return as Bengals' Head Coach in 2026
Las Vegas Raiders

Pete Carroll's Future with Las Vegas Raiders in Doubt
Mike Conley

Nears Return After Missing Four Games
Tee Higgins

Active for Week 16 Against Dolphins
Brandon Clarke

Exits After Brief Appearance Against Wizards
Derrick Jones Jr.

Nears Return From Sprained MCL
Herbert Jones

Head Injury Cuts Night Short
Ivica Zubac

Leaves Early After Suffering Left Ankle Injury
Luka Dončić

Luka Doncic Exits Early With Left Leg Contusion
Tage Thompson

Scores in Sixth Consecutive Game
Jacob Fowler

Posts First Career Shutout
Jonatan Berggren

Totals Three Points Saturday
Jake Evans

to Sit Out Sunday's Game
Zach Werenski

Injured in Saturday's Loss
Frank Nazar

Expected to Miss Four Weeks
Woody Marks

Plans to Play Against Raiders in Week 16
Tee Higgins

Likely to Play at Miami on Sunday
Drake London

Expected to Return in Week 16
Marvin Harrison Jr.

Expected to Play, Will Ease Back In
Romeo Doubs

Questionable to Return Against Bears in Week 16
Jordan Love

Ruled Out with Concussion, Replaced by Malik Willis
Jalen Smith

Expected to Remain in Lineup Sunday
Ayo Dosunmu

Probable for Meeting With Hawks
Jordan Love

Evaluated for Concussion, Questionable to Return
Coby White

Iffy for Sunday
Andrew Wiggins

May Remain Out Sunday
Davion Mitchell

Questionable for Sunday
Tyler Herro

to Miss Fourth Straight Game Sunday
Trae Young

Available for Sunday's Tilt
Doug McDermott

Active on Saturday
Rui Hachimura

Misses Battle of Los Angeles
Mike Matheson

Returns Against Former Team Saturday
Timothy Liljegren

Misses Saturday's Game
Mackie Samoskevich

Out on Saturday
Anthony Cirelli

Available Against Hurricanes
Brandon Hagel

Added to Injured Reserve
Nikita Kucherov

a Game-Time Call Saturday
J.T. Miller

Injured in Saturday's Win
Zach Bogosian

Unavailable Saturday
Brandon Lowe

Pirates Acquire Brandon Lowe in Three-Team Trade
Shane Baz

Orioles Acquire Shane Baz From the Rays
CFB

Darian Mensah Returning to Duke Next Season
CFB

Josh Hoover Linked to Indiana in Transfer Portal
CFB

Arch Manning Agrees to Reduced Compensation for 2026 Season
Michael King

Padres Bring Michael King Back on Three-Year Deal
Logan Webb

Will Pitch for Team USA in World Baseball Classic
Tarik Skubal

Joins Team USA for World Baseball Classic
CFB

Will Muschamp Becoming Next Texas Defensive Coordinator
CFB

Beau Pribula Set to Enter Transfer Portal
Bo Bichette

Willing to Make the Move to Second Base
CFB

Jeremiyah Love Officially Heading to NFL Draft
CFB

Jake Merklinger Leaving Tennessee for Transfer Portal
Mike Trout

Angels Open to Mike Trout Playing Center Field in 2026
CFB

Kansas State's Jayce Brown Intends to Transfer
CFB

Nation's Leading Passer Drew Mestemaker to Enter Transfer Portal
Justin Crawford

Phillies Planning to Start Justin Crawford in Center Field
CFB

Jayden Maiava Signs New Deal to Return to USC
CFB

Aidan Mizell Won't Return to Florida, Entering Transfer Portal
CFB

East Carolina Targeting Jordan Davis as Next Offensive Coordinator
CFB

Michigan QB Jadyn Davis Set to Enter Transfer Portal
CFB

Travis Williams Joining Texas A&M Defensive Staff

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