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FanDuel Lineup Picks (Week 10) - NFL DFS Advice

FanDuel NFL DFS lineup picks and start 'em, sit' em for Week 10. Daily fantasy football sleepers and lineups cheat sheet for FanDuel DFS GPPs and tournaments.

Welcome to RotoBaller's daily fantasy football FanDuel lineup picks for Week 10 of the NFL season. In this article I will be taking you through the best FanDuel DFS plays of the week for this upcoming Sunday.

These FanDuel lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more.

Good luck with your FanDuel DFS lineups!

Be sure to check all of our fantasy football rankings for 2025:

 

FanDuel Quarterbacks - Week 10 DFS Picks

Ryan Fitzpatrick (vs. NYJ, $6,100)

Ryan Fitzpatrick will be behind center for the Buccaneers this week and for the foreseeable future. The combination of price and matchup (plus a little narrative) make it difficult to pass in this spot despite the fact that Mike Evans won’t be on the field this week. The Jets are ranked 21st in pass DVOA and the price will allow spending up at other spots on the slate.

Matthew Stafford (vs. CLE, $8,200)

If you’re feeling a safer option than Fitzpatrick this week, Stafford is the quarterback to turn to. Stafford has been good lately, passing for multiple touchdowns in two of his past three games and over 300 yards in all three. He should be able to do each of those things against a hapless Browns pass defense that ranks 28th in pass DVOA for the season. The only risk for Stafford is that the Lions pull ahead quickly without those scores coming through the air, but with the ineptitude of their ground game that seems unlikely.

 

FanDuel Running Backs - Week 10 DFS Picks

Carlos Hyde (vs. NYG, $6,700)

Carlos Hyde hasn’t been anything special on the ground this season which is obviously not a great statement in reference to a running back. On the other hand, he has been very involved in the pass game which has kept his floor at a safe level. When the 49ers have lost by 10 points or less this season, Hyde has seen an average of 23 touches per game. The Giants are just as inept as the 49ers, if not more, so this should be a close game between two bad teams and allow Hyde to see a healthy dose of touches.

Bilal Powell (@TB, $6,000)

With Matt Forte officially out this week, we can look to Powell as a bargain running back that paves the way to Antonio Brown, LeVeon Bell, or Gronk. While the narrative has been that the Jets rushing attack has been an unreliable mess in terms of workload, the absence of Forte should open sufficient volume for Powell to take advantage of. The Bucs are far from tough on opposing running backs, allowing big games to Adrian Peterson, LeSean McCoy, and the Saints running back committee of late, opening up some more nice value at the running back position.

 

FanDuel Wide Receivers - Week 10 DFS Picks

A.J. Green (@TEN, $7,900) 

A.J. Green has been a story this week, but not because of his play. He should be motivated to perform as a result and he’s in a decent spot to do so. Though Tennessee has shown improvement on defense, most of that improvement has come against opposing rushing attacks. If the Bengals are smart, that’s a big if, they will pepper A.J. Green with targets as has a six-inch height advantage over otherwise impressive rookie Adoree’ Jackson.

Marvin Jones (vs. CLE, $6,400)

Golden Tate has been a reliable option this season, but the price disparity between he and Marvin Jones on FanDuel doesn’t make much sense. Over the past three games, in which Matt Stafford has gotten on track, Jones has put up 18.6, 15.8, and 26.2 FD points respectively. In an A+ matchup there’s no reason to go away from Jones.

 

FanDuel Tight End - Week 10 DFS Pick

Rob Gronkowski (@DEN, $8,100) 

Gronk is a relatively easy choice this week, assuming the ability or desire to pay up at the position. The Broncos still can’t cover opposing tight ends, as they have allowed 14.47 FD points per game to them on the season. Coming off of a bye week, the Patriots will be prepared to take advantage of that huge edge making Gronk worth the premium.

 

FanDuel Defense - Week 10 DFS Pick

Chicago Bears (vs. CIN, $4,300)

The Bears have been a respectable defense all season, especially at home, and the Packers offense has been non-existent since the loss of Aaron Rodgers. It comes as little surprise that they have an implied total of just 16.25 The Bears will be the chalk defense of the week, but at this price point there is good reason why.

 

More Week 10 DFS Analysis

 

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REAL-TIME FANTASY NEWS

Trey Yesavage

Heading to Big Leagues
Will Smith

Placed on 10-Day Injured List
Ivan Demidov

Turning Heads in Rookie Camp
NHL

Calvin de Haan Signs With Swedish Team
Samuel Girard

Skates With Non-Contract Jersey
Mackenzie Blackwood

Dealing With Injury Ahead of Training Camp
Brock Bowers

Officially Questionable for Monday Night
Spencer Knight

Signs Three-Year Extension With Blackhawks
Chris Buescher

May have Another Solid Run at Bristol
Corey Perry

Out 6-8 Weeks Following Surgery
Kyle Busch

Should DFS Players Roster Kyle Busch At Bristol?
Ricky Stenhouse Jr

Is Ricky Stenhouse Jr. too Risky to Consider Rostering At Bristol?
Michael McDowell

Could be A Solid Value Option For Bristol DFS Lineups
Chase Elliott

Consistent Enough to Advance in Playoffs, but Probably Won't Factor for Bristol Win
NASCAR

Bubba Wallace Not as Strong at Bristol as Other Short Tracks
Alex Bowman

Needs to Win to Make Round of 12 but Might Be Able to Do It
Ross Chastain

Has Never Led at Bristol, but Has Been Pretty Consistent
Austin Dillon

Richmond Speed Unlikely to Carry Over to Bristol
Josh Berry

Might Run Well at Bristol, but Almost Certainly Won't Win to Advance
Justin Haley

Bristol One of Justin Haley's Few Recent Bright Spots
Ryan Preece

Seems Slower on Concrete Than on Asphalt
NASCAR

Legacy Motor Club's Short Track Speed Will Likely Hold John H. Nemechek Back
Erik Jones

Definitely Faster This Year, but Short Tracks Still a Liability
Daniel Suarez

Despite Poor Qualifying Run, Daniel Suarez Might Not Be a Great Choice for Place Differential Points
Noah Gragson

Unlikely to Be Fast at Bristol but Still Might Be Worth Considering for DFS
Tarik Skubal

Avoids Serious Injury, Expected to Make Next Start
Xavier Worthy

Officially Ruled Out for Week 2
Austin Ekeler

Suffers Torn Achilles
Quinshon Judkins

Expected to Play Against Ravens
CFB

Austin Simmons Listed As Game-Time Decision Against Arkansas
CFB

Nico Iamaleava Struggles In Fourth Straight Loss
Ukko-Pekka Luukkonen

Dealing With a "Tweak"
BUF

Alexandar Georgiev Joins Sabres on One-Year Deal
Corey Perry

Injured During Pre-Camp Skate
Kyle Larson

Can Kyle Larson Dominate at Bristol Again?
Denny Hamlin

One of the Best at Bristol
Ryan Blaney

All Eyes on Ryan Blaney at Bristol
Chase Briscoe

Whiffs in Qualifying, Will Start 31st in Bristol Night Race
Ty Gibbs

Could Contend at Bristol
Tanner Bibee

Fans 10 in Two-Hit Shutout
Zach Neto

Dealing With Wrist Soreness
Masyn Winn

Shut Down for Rest of Season
Tarik Skubal

to Undergo Imaging on Saturday
Jacory Croskey-Merritt

RapSheet: Jacory Croskey-Merritt Expected to Be Lead Back Moving Forward
Tyler Soderstrom

Scratched on Friday With Groin Tightness
Tarik Skubal

Exits with Side Tightness
CFB

Antonio Williams Out Against Georgia Tech
Ketel Marte

Scratched From Friday's Lineup
Brock Purdy

Officially Ruled Out Against Saints
Jauan Jennings

Given Questionable Tag for Week 2
CFB

CJ Bailey Flashes Again in Win Over Wake Forest
CFB

Jaxson Moi a Game-Time Decision for Tennessee on Saturday
Dallas Goedert

Officially Ruled Out for Week 2
Xavier Worthy

Listed as Doubtful to Play in Week 2
Jayden Reed

Hopes to Return in November Following Surgery
Jean Silva

A Favorite At Noche UFC 3
Kyle Tucker

"Unlikely" to Return When Eligible on Tuesday
Diego Lopes

Set For Noche UFC 3 Main Event
Ketel Marte

Expected to Return on Friday
Rob Font

Looks For His Third Consecutive Win
David Martinez

Set For Noche UFC 3 Co-Main Event
Quinshon Judkins

Questionable to Make NFL Debut in Week 2
Rafa Garcia

An Underdog At Noche UFC 3
Jared Gordon

Looks To Win Back-To-Back Fights
Dustin Stoltzfus

Looks To Return To The Win Column
Kelvin Gastelum

In Dire Need Of Victory
Diego Ferreira

Looks To Get Back In The Win Column
Alexander Hernandez

Looks To Extend His Win Streak
Quang Le

Set For Noche UFC 3 Main Card Opener
Santiago Luna

Set For His Debut At Noche UFC 3
Malcolm Brogdon

Heading to Knicks on One-Year Deal
CFB

David Sanders Jr. Won't Play Against Georgia
Landry Shamet

Staying with the Knicks
CFB

Dylan Edwards Slated to Return on Friday
Jacory Croskey-Merritt

Sees Little Usage in Week 2, Outlook Still Trending Upwards?
Deebo Samuel Sr.

Leads Commanders in Catches, Scores Touchdown Again
Tucker Kraft

Posts Huge Performance on Thursday
Joe Mixon

Lack of Joe Mixon Injury Updates Sparking Concern for Fantasy Managers?
Jayden Reed

Fractures Collarbone, Headed for Injured Reserve
Austin Ekeler

Commanders Fear Austin Ekeler Tore his Achilles
Jesús Luzardo

Jesus Luzardo Strikes Out 10 in Win
Aaron Judge

Matches Yankees Legend with Two-Homer Game
Austin Ekeler

Injured, Carried Off Field with Non-Contact Injury
Jayden Reed

Ruled Out with Shoulder Injury
Quinshon Judkins

Browns Insider Expects NFL to "Come Down Heavy" on a Quinshon Judkins Suspension
Jayden Reed

Questionable to Return on TNF With Shoulder Injury
Anthony Volpe

Playing Through Partially Torn Labrum in his Shoulder
Adam Lowry

Aims for Early-Season Return
Charles Oliveira

Not Eyeing Retirement
CFB

Ryan Williams Expected to Play Against Wisconsin
CFB

Billy Edwards Jr. Unlikely to Play on Saturday
P.J. Washington

Officially Signs Contract Extension
CFB

David Sanders Jr. Questionable to Make Debut Against Georgia
Lauri Markkanen

Big at Both Ends as Finland Books Place in EuroBasket Semis
Luka Dončić

Luka Doncic Notches 39 Points in Losing Effort
NBA

Cam Reddish Expected to Move to Europe
NBA

Trey Lyles Joins Real Madrid
Charles Bassey

Signs Exhibit 10 Deal With Hawks
Sacramento Kings

Terence Davis Waived by Kings
Will Smith

Scratched With Hand Soreness on Wednesday
Ketel Marte

has Foot Contusion, Expected to Play Friday
Shohei Ohtani

Won't Pitch This Weekend
MacKenzie Gore

to Start on Thursday
Ketel Marte

Exits Early on Wednesday
Matthew Knies

Ready for Bigger Role With Maple Leafs
Jack Eichel

Unbothered by Lack of Extension
Sidney Crosby

Not Thinking About Leaving Pittsburgh
SJ

Michael Misa Signs Entry-Level Contract With Sharks
Rutger McGroarty

Nursing an Injury
Anthony Rizzo

Retires
Cameron Champ

the Ultimate Wild Card at Procore
Cameron Young

Looks to Extend Momentum in Napa
Davis Thompson

Searching for a Spark at Procore
Sahith Theegala

Looking to Reignite Form at Procore
Mackenzie Hughes

Aims for Another Strong Showing at Procore
Luke Clanton

Brings Ball-Striking Upside to Napa
Seamus Power

Looking to Overcome Poor Course History at Procore
Joe Highsmith

Hoping to Find Form in Napa
Kristaps Porzingis

Reportedly Still Not Completely Healthy
Kelly Oubre Jr.

Reportedly on the Trade Block
Andre Drummond

Future in Philadelphia in Doubt
Giannis Antetokounmpo

Helps Greece Reach Semis at EuroBasket
Alperen Sengün

Alperen Sengun Posts Historic Triple-Double
Joel Dahmen

Finishes Tied For 15 at Wyndham Championship
Bud Cauley

Finishes Tied for 33rd at BMW Championship
Justin Thomas

Finishes Tied for Seventh at Tour Championship
J.J. Spaun

Finishes Tied for 25th at Tour Championship
Collin Morikawa

Finishes Tied for 19th at Tour Championship
Keith Mitchell

Misses Cut at Wyndham Championship
Ben Griffin

Finishes Tied for 10th at Tour Championship
Patrick Cantlay

Finishes Tied for Second at Tour Championship
Gary Woodland

Could Hang Around at Procore Championship
Karl Vilips

Ready for Napa Valley This Weekend
Taylor Montgomery

Heating Up at the Right Time
Jackson Koivun

May Be a Little Rusty at Procore Championship
Doug Ghim

Looking to Rise Up at Napa Valley
Josh Giddey

Re-Signs With Bulls for Four Years
Shakir Mukhamadullin

Joins Informal Skate
William Eklund

Skates With Sharks
Owen Power

Back at 100 Percent
Tyler Seguin

Cleared for Action
Mathew Barzal

Good to Go for Season Opener
Dustin Wolf

Signs Seven-Year Extension
NBA

Mason Jones Takes His Talents to Australia
NBA

Talen Horton-Tucker Joins Reigning EuroLeague Champions
Malcolm Brogdon

on Knicks' Radar
Andrew Wiggins

Attracting Interest From Lakers
Miami Heat

Heat Interested in Reunion With Precious Achiuwa
New York Knicks

Ben Simmons Reportedly Declined Knicks' Contract Offer
Caio Borralho

Suffers His First UFC Loss
Nassourdine Imavov

Extends Win Streak
Mauricio Ruffy

Gets Submitted
Benoît Saint Denis

Benoit Saint Denis Taps Out Mauricio Ruffy
Paul Craig

Retires After UFC Paris Loss
Modestas Bukauskas

Scores First-Round Knockout
Bolaji Oki

Suffers Second-Round TKO Loss
Mason Jones

Scores Comeback Win

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