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FanDuel Lineup Picks (Week 10) - NFL DFS Advice

FanDuel NFL DFS lineup picks and start 'em, sit' em for Week 10. Daily fantasy football sleepers and lineups cheat sheet for FanDuel DFS GPPs and tournaments.

Welcome to RotoBaller's daily fantasy football FanDuel lineup picks for Week 10 of the NFL season. In this article I will be taking you through the best FanDuel DFS plays of the week for this upcoming Sunday.

These FanDuel lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more.

Good luck with your FanDuel DFS lineups!

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FanDuel Quarterbacks - Week 10 DFS Picks

Ryan Fitzpatrick (vs. NYJ, $6,100)

Ryan Fitzpatrick will be behind center for the Buccaneers this week and for the foreseeable future. The combination of price and matchup (plus a little narrative) make it difficult to pass in this spot despite the fact that Mike Evans won’t be on the field this week. The Jets are ranked 21st in pass DVOA and the price will allow spending up at other spots on the slate.

Matthew Stafford (vs. CLE, $8,200)

If you’re feeling a safer option than Fitzpatrick this week, Stafford is the quarterback to turn to. Stafford has been good lately, passing for multiple touchdowns in two of his past three games and over 300 yards in all three. He should be able to do each of those things against a hapless Browns pass defense that ranks 28th in pass DVOA for the season. The only risk for Stafford is that the Lions pull ahead quickly without those scores coming through the air, but with the ineptitude of their ground game that seems unlikely.

 

FanDuel Running Backs - Week 10 DFS Picks

Carlos Hyde (vs. NYG, $6,700)

Carlos Hyde hasn’t been anything special on the ground this season which is obviously not a great statement in reference to a running back. On the other hand, he has been very involved in the pass game which has kept his floor at a safe level. When the 49ers have lost by 10 points or less this season, Hyde has seen an average of 23 touches per game. The Giants are just as inept as the 49ers, if not more, so this should be a close game between two bad teams and allow Hyde to see a healthy dose of touches.

Bilal Powell (@TB, $6,000)

With Matt Forte officially out this week, we can look to Powell as a bargain running back that paves the way to Antonio Brown, LeVeon Bell, or Gronk. While the narrative has been that the Jets rushing attack has been an unreliable mess in terms of workload, the absence of Forte should open sufficient volume for Powell to take advantage of. The Bucs are far from tough on opposing running backs, allowing big games to Adrian Peterson, LeSean McCoy, and the Saints running back committee of late, opening up some more nice value at the running back position.

 

FanDuel Wide Receivers - Week 10 DFS Picks

A.J. Green (@TEN, $7,900) 

A.J. Green has been a story this week, but not because of his play. He should be motivated to perform as a result and he’s in a decent spot to do so. Though Tennessee has shown improvement on defense, most of that improvement has come against opposing rushing attacks. If the Bengals are smart, that’s a big if, they will pepper A.J. Green with targets as has a six-inch height advantage over otherwise impressive rookie Adoree’ Jackson.

Marvin Jones (vs. CLE, $6,400)

Golden Tate has been a reliable option this season, but the price disparity between he and Marvin Jones on FanDuel doesn’t make much sense. Over the past three games, in which Matt Stafford has gotten on track, Jones has put up 18.6, 15.8, and 26.2 FD points respectively. In an A+ matchup there’s no reason to go away from Jones.

 

FanDuel Tight End - Week 10 DFS Pick

Rob Gronkowski (@DEN, $8,100) 

Gronk is a relatively easy choice this week, assuming the ability or desire to pay up at the position. The Broncos still can’t cover opposing tight ends, as they have allowed 14.47 FD points per game to them on the season. Coming off of a bye week, the Patriots will be prepared to take advantage of that huge edge making Gronk worth the premium.

 

FanDuel Defense - Week 10 DFS Pick

Chicago Bears (vs. CIN, $4,300)

The Bears have been a respectable defense all season, especially at home, and the Packers offense has been non-existent since the loss of Aaron Rodgers. It comes as little surprise that they have an implied total of just 16.25 The Bears will be the chalk defense of the week, but at this price point there is good reason why.

 

More Week 10 DFS Analysis

 

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REAL-TIME FANTASY NEWS

Jerami Grant

May Miss Saturday's Game
Jrue Holiday

Questionable for Saturday
Aaron Gordon

Likely to Face Wizards
Jamal Murray

Listed as Probable for Saturday
Stephon Castle

Questionable for Saturday
Keon Ellis

Out Friday Night
Tari Eason

Still Out Friday
Deni Avdija

Unlikely to Play Against Lakers
Deandre Ayton

Questionable for Saturday's Tilt
Luka Dončić

Luka Doncic Won't Play Saturday
Domantas Sabonis

Officially Active Friday
Cade Cunningham

Considered Probable for Saturday
Jaime Jaquez Jr.

to Sit Out Second Consecutive Game
Tyler Herro

Questionable to Play Saturday
Jalen Brunson

Iffy for Meeting With Suns
Devin Booker

Uncertain for Saturday
Nicolas Batum

Starting Against Raptors
Julian Phillips

Returns From Two-Game Absence
Kevin Huerter

Available Against Nets
Ivica Zubac

Upgraded to Available
John Collins

Good to Go Friday
Atlanta Falcons

Kevin Stefanski the Favorite for Falcons Head-Coaching Job
Matt Boldy

Placed on Injured Reserve
Ross Colton

Good to Go Friday
Will Smith

Returns Against Red Wings
Shayne Gostisbehere

Out Friday
Brad Marchand

Remains Out Friday
Joel Armia

Returns From Five-Game Absence
Chris Kreider

a Game-Time Call Friday
Troy Terry

Cutter Gauthier Available Friday
Leo Carlsson

Sits Out Second Consecutive Game
CFB

Darian Mensah Entering Transfer Portal
Sam Darnold

Seahawks "Optimistic" That Sam Darnold Will Play on Saturday
Nico Collins

Officially Ruled Out for Divisional Round
Rome Odunze

Questionable for Divisional Round
J.T. Realmuto

Signs Three-Year Deal to Return to Phillies
Bo Bichette

Agrees to Three-Year Contract With Mets
CFB

Weber State Signs former Ohio State, Cal Quarterback Devin Brown
Bo Bichette

Phillies the "Overwhelming" Favorite to Sign Bo Bichette
Mark Scheifele

Leads Jets to Victory Thursday
Tage Thompson

Records Season-High Five Points Thursday
Jack Eichel

Notches Four Points Thursday
Ilya Sorokin

Shuts Out Oilers With 35 Saves
Andrew Peeke

Not Expected to Be Out Long-Term
William Nylander

Aggravates Lower-Body Injury Thursday
Ross Colton

Uncertain for Friday
Josh Lowe

Angels Acquire Josh Lowe in Three-Team Trade
Kyle Tucker

Signs Four-Year Contract With Dodgers
Ricky Pearsall

Questionable to Play on Saturday Night
Sam Darnold

Questionable With Oblique Injury, Expected to Play
Damon Severson

Back for Blue Jackets Thursday
Adin Hill

Available Thursday Night
Brandon Montour

Activated From Injured Reserve
Joel Eriksson Ek

Misses Third Straight Game Thursday
Jonas Brodin

Placed on Injured Reserve, Out Week-to-Week
Clayton Kershaw

to Pitch for Team USA in World Baseball Classic
Patrick Mahomes

Says Rehab Going "Great," Goal is 2026 Week 1 Return
Nico Collins

a "Long Shot" to Play in Divisional Round
CFB

Auburn, Ohio State the Lead Suitors for Kyle Parker
CFB

Oregon QB Transfer Bryson Beaver Linked to Georgia, Kentucky
CFB

Jake Merklinger Commits to UConn
New York Giants

John Harbaugh Finalizing Deal With Giants
Ben Griffin

Looks To Stay Hot In 2026
New York Giants

Giants Making "Massive Push" to Hire John Harbaugh on Wednesday
Ranger Suárez

Ranger Suarez Agrees to Five-Year Deal With Red Sox
CFB

Dante Moore Not Entering 2026 NFL Draft, Will Return to Oregon
NFL

Mike Tomlin Doesn't Plan to Coach in 2026
Travis Hunter

Expected to Play More Defense in 2026
CFB

FBS Coaches Unanimously Vote to Expand Redshirt Eligibility to Nine Games
CFB

Ohio State Transfer Mylan Graham Signs with Notre Dame
CFB

Caden Durham Withdraws from Transfer Portal, Will Stay at LSU
Jordan Spieth

Perhaps the Most Intriguing Player at Sony Open
Aaron Rai

Looking For Putting Confidence at Waialae Country Club
Collin Morikawa

Isn't The Safe Play He Used to Be Ahead of Sony Open
Kurt Kitayama

Needs His Putting to Turn Around For Success at Year's First Event
Ryan Weathers

Yankees Add Rotation Depth, Acquire Ryan Weathers in Four-Player Deal
Los Angeles Chargers

Chargers Fire Offensive Coordinator Greg Roman
Pittsburgh Steelers

Mike Tomlin Stepping Down as Steelers Head Coach
CFB

Georgia Tech the Favorite to Land Justice Haynes?
Nolan Arenado

Cardinals Trade Nolan Arenado to Diamondbacks
Tom Kim

Desperately Needs a Solid Week at Sony Open
Billy Horschel

Hoping For a Fast Start to New Season at Sony Open
Corey Conners

Looks to Have a Return to Form in 2026
PGA

Chris Gotterup a Decent Play at Sony Open
Gary Woodland

Could Prosper at the Sony Open
Keith Mitchell

Unlikely to Contend at Sony Open
Robert MacIntyre

Looking for a Good Performance at the Sony Open
Michael Kim

Hopes to Start Sony Open Better This Week
Tom Hoge

Tries to Erase Poor 2025 Second Half in Hawaii
Brian Harman

Seeks Fresh Start in Hawaii
Eric Cole

Looks to Last Year for Success at Sony Open
Daniel Berger

Starts Off 2026 at Sony Open
Nico Collins

Suffers Concussion Against Steelers
Nico Collins

Carted to Locker Room for Concussion Evaluation
Kyle Tucker

Mets Meet With Kyle Tucker
Dalton Kincaid

"Should be Fine" for Divisional Round
Brooks Koepka

Officially Returning To PGA Tour
Tucker Kraft

Hopes to be Ready for Week 1 of Next Season
CFB

Georgia Lands Kentucky Transfer Dante Dowdell
Matthew Stafford

has "Little Sprain," Should be "Good to Go"
CFB

Sam Leavitt Expected to Sign with LSU
Green Bay Packers

Packers Expected to Work Out New Deal With Matt LaFleur in the "Coming Days"
CFB

Dylan Raiola Commits to Oregon
CFB

Isaiah Horton Landing with Texas A&M
George Kittle

Suffers Torn Achilles on Sunday
MacKenzie Gore

Yankees Pursuing Trade for MacKenzie Gore

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP