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FanDuel Lineup Picks (Week 10) - NFL DFS Advice

FanDuel NFL DFS lineup picks and start 'em, sit' em for Week 10. Daily fantasy football sleepers and lineups cheat sheet for FanDuel DFS GPPs and tournaments.

Welcome to RotoBaller's daily fantasy football FanDuel lineup picks for Week 10 of the NFL season. In this article I will be taking you through the best FanDuel DFS plays of the week for this upcoming Sunday.

These FanDuel lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more.

Good luck with your FanDuel DFS lineups!

 

FanDuel Quarterbacks - Week 10 DFS Picks

Ryan Fitzpatrick (vs. NYJ, $6,100)

Ryan Fitzpatrick will be behind center for the Buccaneers this week and for the foreseeable future. The combination of price and matchup (plus a little narrative) make it difficult to pass in this spot despite the fact that Mike Evans won’t be on the field this week. The Jets are ranked 21st in pass DVOA and the price will allow spending up at other spots on the slate.

Matthew Stafford (vs. CLE, $8,200)

If you’re feeling a safer option than Fitzpatrick this week, Stafford is the quarterback to turn to. Stafford has been good lately, passing for multiple touchdowns in two of his past three games and over 300 yards in all three. He should be able to do each of those things against a hapless Browns pass defense that ranks 28th in pass DVOA for the season. The only risk for Stafford is that the Lions pull ahead quickly without those scores coming through the air, but with the ineptitude of their ground game that seems unlikely.

 

FanDuel Running Backs - Week 10 DFS Picks

Carlos Hyde (vs. NYG, $6,700)

Carlos Hyde hasn’t been anything special on the ground this season which is obviously not a great statement in reference to a running back. On the other hand, he has been very involved in the pass game which has kept his floor at a safe level. When the 49ers have lost by 10 points or less this season, Hyde has seen an average of 23 touches per game. The Giants are just as inept as the 49ers, if not more, so this should be a close game between two bad teams and allow Hyde to see a healthy dose of touches.

Bilal Powell (@TB, $6,000)

With Matt Forte officially out this week, we can look to Powell as a bargain running back that paves the way to Antonio Brown, LeVeon Bell, or Gronk. While the narrative has been that the Jets rushing attack has been an unreliable mess in terms of workload, the absence of Forte should open sufficient volume for Powell to take advantage of. The Bucs are far from tough on opposing running backs, allowing big games to Adrian Peterson, LeSean McCoy, and the Saints running back committee of late, opening up some more nice value at the running back position.

 

FanDuel Wide Receivers - Week 10 DFS Picks

A.J. Green (@TEN, $7,900) 

A.J. Green has been a story this week, but not because of his play. He should be motivated to perform as a result and he’s in a decent spot to do so. Though Tennessee has shown improvement on defense, most of that improvement has come against opposing rushing attacks. If the Bengals are smart, that’s a big if, they will pepper A.J. Green with targets as has a six-inch height advantage over otherwise impressive rookie Adoree’ Jackson.

Marvin Jones (vs. CLE, $6,400)

Golden Tate has been a reliable option this season, but the price disparity between he and Marvin Jones on FanDuel doesn’t make much sense. Over the past three games, in which Matt Stafford has gotten on track, Jones has put up 18.6, 15.8, and 26.2 FD points respectively. In an A+ matchup there’s no reason to go away from Jones.

 

FanDuel Tight End - Week 10 DFS Pick

Rob Gronkowski (@DEN, $8,100) 

Gronk is a relatively easy choice this week, assuming the ability or desire to pay up at the position. The Broncos still can’t cover opposing tight ends, as they have allowed 14.47 FD points per game to them on the season. Coming off of a bye week, the Patriots will be prepared to take advantage of that huge edge making Gronk worth the premium.

 

FanDuel Defense - Week 10 DFS Pick

Chicago Bears (vs. CIN, $4,300)

The Bears have been a respectable defense all season, especially at home, and the Packers offense has been non-existent since the loss of Aaron Rodgers. It comes as little surprise that they have an implied total of just 16.25 The Bears will be the chalk defense of the week, but at this price point there is good reason why.

 

More Week 10 DFS Analysis

 

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REAL-TIME FANTASY NEWS

Pascal Siakam

Iffy for Sunday
Chet Holmgren

Available Against Knicks Sunday
Norman Powell

May Miss Sunday's Game
Jaylen Brown

Questionable Sunday
Kevin Porter Jr.

Unlikely to Return This Season
Denny Hamlin

the Favorite to Win at Martinsville
Ryan Blaney

Should Contend at Martinsville
Tyler Reddick

Should Come Back Down to Earth at Martinsville
Joey Logano

Will Be Strong at Martinsville
Deshaun Watson

in "Pole Position" to be Week 1 Starting QB?
NASCAR

Bubba Wallace Looking to Rebound at Martinsville
Shane Van Gisbergen

Shane van Gisbergen Showing Progress, Qualifies Fifth at Martinsville
Gabriel Vilardi

has a Two-Point Performance
Ivan Demidov

Collects Two More Points on Saturday
Alexandre Sarr

Out Sunday vs. Trail Blazers
Neemias Queta

Questionable for Sunday
Jayson Tatum

Could Rest on Back-to-Back
Derrick White

Could Miss Hornets Game
Immanuel Quickley

Remains Sidelined vs. Magic
Brandon Ingram

Questionable Against Orlando
Luka Dončić

Luka Doncic to Serve One-Game Suspension Monday
Walter Clayton Jr.

is Available for Saturday's Game
Dylan Cease

Fans 12 in Blue Jays Debut on Saturday
Jahmai Mashack

is Returning on Saturday
Guerschon Yabusele

is Absent on Saturday
Malik Monk

Moves into Starting Five on Saturday
Kyler Murray

Dynasty Value Gets New Life With Move to Minnesota
Jonathan Kuminga

to Sit Out on Saturday
Onyeka Okongwu

Won't Play on Saturday
Rachaad White

Is Rachaad White the New RB1 for the Commanders?
Jock Landale

is Cleared for Saturday's Game
Dyson Daniels

is Ruled Out for Saturday
Shane Wright

Exits Early Saturday
Connor Zary

Remains Out Saturday Night
Noah Laba

a Game-Time Call Sunday
Jonathan Quick

to Remain Unavailable Sunday
Stefon Diggs

Still a Free Agent With April Approaching
Joel Hanley

to Miss Rest of Season
Alvin Kamara

Workload Expected to Look Drastically Different in 2026
Ethen Frank

Remains Out Saturday
Robert Thomas

Available Saturday
Andrew Vaughn

Needs Hand Surgery, Expected to be Out 4-6 Weeks
Jacob deGrom

"Confident" he Will Make his Next Start
Trey Benson

Facing Uphill Battle for Playing Time in Arizona
Jacory Croskey-Merritt

Can Jacory Croskey-Merritt Emerge as the Clear RB1 in Washington?
Lamar Jackson

Looking for Return to Full Health in 2026
Sean Tucker

Remains Buried on Buccaneers' Running Back Depth Chart
Jake Tonges

Appears Likely to Enter 2026 Atop 49ers' Tight End Depth Chart
NFL

Can Ja'Kobi Lane Carve Out a Fantasy-Relevant Role as a Rookie?
Chig Okonkwo

Instantly Jumping to Fantasy Relevance in Washington?
Aaron Jones Sr.

Set for Familiar Role in 2026?
Brandon Aiyuk

a Buy-Low Candidate in Dynasty Leagues?
Romeo Doubs

the New No. 1 Target in New England?
Daniel Jones

a QB1 if Ready for Season Opener?
Jacob deGrom

Scratched From Saturday's Start Due to Neck Stiffness
Jeferson Quero

Brewers Calling Up Catching Prospect Jeferson Quero
Josh Allen

Still the Top Dog at QB in Fantasy
Jared Goff

Should Have Safe Floor as QB1 Again Under New Offensive Coordinator
Jacoby Brissett

Will Jacoby Brissett be on the Streaming Radar Again in 2026?
NFL

Kaytron Allen Should Attract Plenty of Interest in 2026 NFL Draft
NFL

Makai Lemon a Polarizing Receiver Prospect Heading into This Year's Draft
David Pastrnak

Riding 11-Game Point Streak
John Gibson

Gets Back on Track Friday
J.T. Miller

Bags Three Points Against Blackhawks
Tage Thompson

Picks Up 400th Career Point
Patrick Kane

Collects Two Points in Friday's Win
Nick Lardis

Pots Another Goal Friday Night
Shayne Gostisbehere

Could Be an Option Saturday
Nique Clifford

Could Return Saturday
Deyvison De Los Santos

Marlins Promote Deyvison De Los Santos to Major Leagues
Moritz Seider

Assists on Two Goals Against the Sabres
Shea Langeliers

Hits Two Home Runs on Opening Day
Kevin Gausman

Picks Up No-Decision But Strikes Out 11 on Opening Day
Alex DeBrincat

Picks Up Three Points Versus Buffalo
Tanner Bibee

Day-to-Day, Could Make his Next Start
Dylan Garand

Starts Friday
Noah Ostlund

Won't Play Friday
Connor Zary

Returns to Practice
Shane Baz

Orioles Agree to Five-Year Extension
Jeremy Peña

Jeremy Pena Making Season Debut on Friday Against Angels
Tiger Woods

Involved In Rollover Car Crash
Tanner Bibee

Shoulder Issue Not Considered Serious
Joe Pyfer

Set For UFC Seattle Main Event
Israel Adesanya

Returns At UFC Seattle
Maycee Barber

Looks To Extend Her Win Streak To Eight
Alexa Grasso

Looks To Get Back In The Win Column
Dominic Canzone

a Top Pickup After Two-Homer Game
Niko Price

In Dire Need Of Victory
Michael Chiesa

Set For Retirement Fight
Chase DeLauter

Launches Two Home Runs, Emerges as Top Waiver-Wire Target
Lerryan Douglas

Set For His UFC Debut
Julian Erosa

Looks To Bounce Back
Tanner Bibee

Leaves Opening Day Start Early With Shoulder Inflammation
Cristopher Sánchez

Cristopher Sanchez Makes a Statement on Opening Day With 10 Strikeouts
Kevin McGonigle

has Four Hits in Impressive MLB Debut
Nico Hoerner

Cubs Agree to Six-Year Deal With Nico Hoerner
Jacob Misiorowski

Shows Off his High-Strikeout Upside in Opening Day Win
Paul Skenes

Greeted Harshly by Mets on Opening Day
Brandon Lowe

Hits Two Home Runs on Opening Day
Ryan Fox

a High-Upside Value in Houston
Marco Penge

a Boom-or-Bust Option in Houston
Aaron Rai

Looks to Bounce Back in Houston
Jason Day

a Volatile Option at the Texas Children's Houston Open
Harris English

Eyes a Bounce-Back at the Texas Children's Houston Open
Ben Griffin

Looks for Turnaround at the Texas Children's Houston Open
Rickie Fowler

Brings Strong Form Into Texas Children's Houston Open
Ryan Gerard

Can Continue Rolling at Texas Children's Houston Open
Pierceson Coody

Bounces Back at Valspar Championship
Rasmus Hojgaard

Trying to Get Back on Track at Texas Children's Houston Open
Michael Thorbjornsen

Playing Well Heading to Texas Children's Houston Open
Harry Hall

Looking for Consistency at Texas Children's Houston Open
Brooks Koepka

Continues Building Momentum
Scottie Scheffler

Withdraws From Texas Children's Houston Open
Luke Clanton

Might Have a Problem in Houston
Sam Stevens

Happy to See Houston This Week
Keith Mitchell

Tries to Rebound After The Players Championship
Will Zalatoris

Returning This Week at Houston
Wyndham Clark

Trending in the Wrong Direction Heading to Houston
Shane Lowry

Seeking Better Luck in Houston This Weekend
Lerone Murphy

Suffers His First Loss
Movsar Evloev

Edges Out Lerone Murphy
CFB

Notre Dame Ranks No. 1 in Returning Production for 2026
Michael Aswell

Jr. Drops Decision At UFC London
Michael Aswell

Luke Riley Outclasses Michael Aswell Jr.
Sam Patterson

Suffers Unanimous-Decision Loss
Michael Page

Wins Lackluster Decision
Austen Lane

Suffers First-Round TKO Loss
Iwo Baraniewski

Delivers 28-Second TKO
RANKINGS
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1B
2B
3B
SS
OF
SP
RP

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QB
RB
WR
TE
K
DEF