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FanDuel Lineup Picks (Week 10) - NFL DFS Advice

FanDuel NFL DFS lineup picks and start 'em, sit' em for Week 10. Daily fantasy football sleepers and lineups cheat sheet for FanDuel DFS GPPs and tournaments.

Welcome to RotoBaller's daily fantasy football FanDuel lineup picks for Week 10 of the NFL season. In this article I will be taking you through the best FanDuel DFS plays of the week for this upcoming Sunday.

These FanDuel lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more.

Good luck with your FanDuel DFS lineups!

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FanDuel Quarterbacks - Week 10 DFS Picks

Ryan Fitzpatrick (vs. NYJ, $6,100)

Ryan Fitzpatrick will be behind center for the Buccaneers this week and for the foreseeable future. The combination of price and matchup (plus a little narrative) make it difficult to pass in this spot despite the fact that Mike Evans won’t be on the field this week. The Jets are ranked 21st in pass DVOA and the price will allow spending up at other spots on the slate.

Matthew Stafford (vs. CLE, $8,200)

If you’re feeling a safer option than Fitzpatrick this week, Stafford is the quarterback to turn to. Stafford has been good lately, passing for multiple touchdowns in two of his past three games and over 300 yards in all three. He should be able to do each of those things against a hapless Browns pass defense that ranks 28th in pass DVOA for the season. The only risk for Stafford is that the Lions pull ahead quickly without those scores coming through the air, but with the ineptitude of their ground game that seems unlikely.

 

FanDuel Running Backs - Week 10 DFS Picks

Carlos Hyde (vs. NYG, $6,700)

Carlos Hyde hasn’t been anything special on the ground this season which is obviously not a great statement in reference to a running back. On the other hand, he has been very involved in the pass game which has kept his floor at a safe level. When the 49ers have lost by 10 points or less this season, Hyde has seen an average of 23 touches per game. The Giants are just as inept as the 49ers, if not more, so this should be a close game between two bad teams and allow Hyde to see a healthy dose of touches.

Bilal Powell (@TB, $6,000)

With Matt Forte officially out this week, we can look to Powell as a bargain running back that paves the way to Antonio Brown, LeVeon Bell, or Gronk. While the narrative has been that the Jets rushing attack has been an unreliable mess in terms of workload, the absence of Forte should open sufficient volume for Powell to take advantage of. The Bucs are far from tough on opposing running backs, allowing big games to Adrian Peterson, LeSean McCoy, and the Saints running back committee of late, opening up some more nice value at the running back position.

 

FanDuel Wide Receivers - Week 10 DFS Picks

A.J. Green (@TEN, $7,900) 

A.J. Green has been a story this week, but not because of his play. He should be motivated to perform as a result and he’s in a decent spot to do so. Though Tennessee has shown improvement on defense, most of that improvement has come against opposing rushing attacks. If the Bengals are smart, that’s a big if, they will pepper A.J. Green with targets as has a six-inch height advantage over otherwise impressive rookie Adoree’ Jackson.

Marvin Jones (vs. CLE, $6,400)

Golden Tate has been a reliable option this season, but the price disparity between he and Marvin Jones on FanDuel doesn’t make much sense. Over the past three games, in which Matt Stafford has gotten on track, Jones has put up 18.6, 15.8, and 26.2 FD points respectively. In an A+ matchup there’s no reason to go away from Jones.

 

FanDuel Tight End - Week 10 DFS Pick

Rob Gronkowski (@DEN, $8,100) 

Gronk is a relatively easy choice this week, assuming the ability or desire to pay up at the position. The Broncos still can’t cover opposing tight ends, as they have allowed 14.47 FD points per game to them on the season. Coming off of a bye week, the Patriots will be prepared to take advantage of that huge edge making Gronk worth the premium.

 

FanDuel Defense - Week 10 DFS Pick

Chicago Bears (vs. CIN, $4,300)

The Bears have been a respectable defense all season, especially at home, and the Packers offense has been non-existent since the loss of Aaron Rodgers. It comes as little surprise that they have an implied total of just 16.25 The Bears will be the chalk defense of the week, but at this price point there is good reason why.

 

More Week 10 DFS Analysis

 

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REAL-TIME FANTASY NEWS

Ja Morant

to Miss Second Straight Game Saturday
Brandon Lowe

Pirates Acquire Brandon Lowe in Three-Team Trade
RJ Barrett

to Remain Out Saturday
Jakob Poeltl

Facing Another Potential Absence Saturday
Jerami Grant

Picks Up Questionable Tag
Deandre Ayton

to Miss Matchup Against Clippers Saturday
Lauri Markkanen

Unlikely to Play Saturday
Klay Thompson

Iffy for Saturday
Anthony Davis

Expected to Play Saturday
James Harden

Available Saturday
Domantas Sabonis

to Miss 4-5 More Weeks
Anthony Edwards

Returns Without Minutes Restriction Friday
Zach Collins

Upgraded to Available Friday
Tre Jones

Available With Minutes Restriction
Ayo Dosunmu

Returns From Three-Game Absence
Kasparas Jakucionis

Makes First Career Start Friday
Davion Mitchell

Ruled Out Friday
Craig Porter Jr.

Skips Friday's Game
Sam Hauser

Available Versus Heat
Shane Baz

Orioles Acquire Shane Baz From the Rays
Andrew Wiggins

Misses Friday's Action
Donovan Mitchell

Unavailable Friday Due to Illness
Jonathan Marchessault

Out Day-to-Day
Tristan Jarry

Oilers Place Tristan Jarry on Injured Reserve
Patrick Kane

to Remain Out Saturday
Shea Theodore

Considered Week-to-Week
Karl-Anthony Towns

& Josh Hart Active Friday Night
Jack Eichel

to Miss at Least Two More Games
Davante Adams

Likely Won't Play in Week 17
Jordan Martinook

Misses Friday's Contest
Evan Rodrigues

Available Against Hurricanes
Tyler Seguin

Undergoes Surgery, to Be Re-Evaluated After Olympics
Marvin Harrison Jr.

Listed as Questionable for Week 16
Drake London

Expected to Play Sunday
Tee Higgins

Questionable to Play in Week 16
Michael Carter

Will Start at RB in Week 16
Dalton Kincaid

Will Practice on Friday, Expected to Play on Sunday
Garrett Wilson

Shelved for Remainder of 2025
CFB

Darian Mensah Returning to Duke Next Season
CFB

Josh Hoover Linked to Indiana in Transfer Portal
CFB

Arch Manning Agrees to Reduced Compensation for 2026 Season
Zach Werenski

Enjoys Second Consecutive Multi-Goal Game
Logan Thompson

Collects Second Shutout of the Season
Linus Ullmark

Blanks Penguins Thursday
Tyson Kozak

Hurt Against Flyers
Conor Timmins

to Miss 6-8 Weeks With Broken Leg
Tristan Jarry

Sustains Lower-Body Injury Versus Bruins
Anthony Cirelli

Injured in Thursday's Loss
Kenneth Walker III

Breaks Off Long Touchdown in Comeback Win vs. Rams
Matthew Stafford

Racks Up Highest Yardage Total in Over a Decade
Puka Nacua

Delivers Career-Best Performance on Thursday Night Football
Michael King

Padres Bring Michael King Back on Three-Year Deal
Logan Webb

Will Pitch for Team USA in World Baseball Classic
Tarik Skubal

Joins Team USA for World Baseball Classic
Jakobi Meyers

Jaguars Agree to Three-Year Extension With Jakobi Meyers
Davante Adams

Officially Out on Thursday Night
Michael Kesselring

Available After 14-Game Absence
Peyton Krebs

Good to Go Thursday
Jake Bean

Set for Surgery, Out Indefinitely
Mike Matheson

Misses Second Straight Game Thursday
Andrei Vasilevskiy

Back for Lightning Thursday
Ryan McDonagh

Available Thursday
Devin Neal

Placed on Injured Reserve, Will Not Return in 2025
CFB

Will Muschamp Becoming Next Texas Defensive Coordinator
Christian Watson

Questionable for Week 16
Josh Jacobs

Listed as Questionable for Saturday Night
T.J. Watt

Unlikely to Play in Week 16
D'Andre Swift

Questionable to Face the Packers
Rome Odunze

Ruled Out for Week 16
Jawhar Jordan

Could be in for Significant Workload Against Raiders
Rome Odunze

Expected to Miss Third Straight Game
CFB

Beau Pribula Set to Enter Transfer Portal
Josh Jacobs

Expected to Play in Week 16
Bo Bichette

Willing to Make the Move to Second Base
CFB

Jeremiyah Love Officially Heading to NFL Draft
CFB

Jake Merklinger Leaving Tennessee for Transfer Portal
Mike Trout

Angels Open to Mike Trout Playing Center Field in 2026
CFB

Kansas State's Jayce Brown Intends to Transfer
CFB

Nation's Leading Passer Drew Mestemaker to Enter Transfer Portal
Justin Crawford

Phillies Planning to Start Justin Crawford in Center Field
CFB

Jayden Maiava Signs New Deal to Return to USC
CFB

Aidan Mizell Won't Return to Florida, Entering Transfer Portal
CFB

East Carolina Targeting Jordan Davis as Next Offensive Coordinator
CFB

Michigan QB Jadyn Davis Set to Enter Transfer Portal
CFB

Travis Williams Joining Texas A&M Defensive Staff
CFB

Dylan Raiola Entering His Name into Transfer Portal
CFB

Cincinnati's Brendan Sorsby Plans to Transfer When Portal Opens
Adolis García

Adolis Garcia, Phillies Finalizing One-Year Deal on Monday
Brandon Royval

Suffers First-Round TKO Loss
CFB

Baylor, LSU, Miami Among Potential Suitors for DJ Lagway
CFB

Aidan Chiles Will Enter Transfer Portal
Manel Kape

Shines At UFC Vegas 112
Kevin Vallejos

Gets Second-Round Knockout Win
Giga Chikadze

Suffers His First Career Knockout Loss
CFB

Quarterback DJ Lagway Entering Transfer Portal
Cesar Almeida

Gets Dominated
Cezary Oleksiejczuk

Wins Sixth Fight In A Row
Morgan Charrière

Morgan Charriere Suffers First-Round Knockout Loss
Melquizael Costa

Gets First-Round Knockout Win
Marcus Buchecha

Still Winless In The UFC
Kennedy Nzechukwu

And Marcus Buchecha Fight To Draw
Lance Gibson jr

Lance Gibson Jr. Drops Decision In His UFC Debut
King Green

Gets Back In The Win Column
Kenley Jansen

Agrees to One-Year Deal With Tigers
Merrill Kelly

Returns to Diamondbacks on Two-Year Deal

RANKINGS

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WR
TE
K
DEF
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1B
2B
3B
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SP
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