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FanDuel Lineup Picks (Week 10) - NFL DFS Advice

FanDuel NFL DFS lineup picks and start 'em, sit' em for Week 10. Daily fantasy football sleepers and lineups cheat sheet for FanDuel DFS GPPs and tournaments.

Welcome to RotoBaller's daily fantasy football FanDuel lineup picks for Week 10 of the NFL season. In this article I will be taking you through the best FanDuel DFS plays of the week for this upcoming Sunday.

These FanDuel lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more.

Good luck with your FanDuel DFS lineups!

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FanDuel Quarterbacks - Week 10 DFS Picks

Ryan Fitzpatrick (vs. NYJ, $6,100)

Ryan Fitzpatrick will be behind center for the Buccaneers this week and for the foreseeable future. The combination of price and matchup (plus a little narrative) make it difficult to pass in this spot despite the fact that Mike Evans won’t be on the field this week. The Jets are ranked 21st in pass DVOA and the price will allow spending up at other spots on the slate.

Matthew Stafford (vs. CLE, $8,200)

If you’re feeling a safer option than Fitzpatrick this week, Stafford is the quarterback to turn to. Stafford has been good lately, passing for multiple touchdowns in two of his past three games and over 300 yards in all three. He should be able to do each of those things against a hapless Browns pass defense that ranks 28th in pass DVOA for the season. The only risk for Stafford is that the Lions pull ahead quickly without those scores coming through the air, but with the ineptitude of their ground game that seems unlikely.

 

FanDuel Running Backs - Week 10 DFS Picks

Carlos Hyde (vs. NYG, $6,700)

Carlos Hyde hasn’t been anything special on the ground this season which is obviously not a great statement in reference to a running back. On the other hand, he has been very involved in the pass game which has kept his floor at a safe level. When the 49ers have lost by 10 points or less this season, Hyde has seen an average of 23 touches per game. The Giants are just as inept as the 49ers, if not more, so this should be a close game between two bad teams and allow Hyde to see a healthy dose of touches.

Bilal Powell (@TB, $6,000)

With Matt Forte officially out this week, we can look to Powell as a bargain running back that paves the way to Antonio Brown, LeVeon Bell, or Gronk. While the narrative has been that the Jets rushing attack has been an unreliable mess in terms of workload, the absence of Forte should open sufficient volume for Powell to take advantage of. The Bucs are far from tough on opposing running backs, allowing big games to Adrian Peterson, LeSean McCoy, and the Saints running back committee of late, opening up some more nice value at the running back position.

 

FanDuel Wide Receivers - Week 10 DFS Picks

A.J. Green (@TEN, $7,900) 

A.J. Green has been a story this week, but not because of his play. He should be motivated to perform as a result and he’s in a decent spot to do so. Though Tennessee has shown improvement on defense, most of that improvement has come against opposing rushing attacks. If the Bengals are smart, that’s a big if, they will pepper A.J. Green with targets as has a six-inch height advantage over otherwise impressive rookie Adoree’ Jackson.

Marvin Jones (vs. CLE, $6,400)

Golden Tate has been a reliable option this season, but the price disparity between he and Marvin Jones on FanDuel doesn’t make much sense. Over the past three games, in which Matt Stafford has gotten on track, Jones has put up 18.6, 15.8, and 26.2 FD points respectively. In an A+ matchup there’s no reason to go away from Jones.

 

FanDuel Tight End - Week 10 DFS Pick

Rob Gronkowski (@DEN, $8,100) 

Gronk is a relatively easy choice this week, assuming the ability or desire to pay up at the position. The Broncos still can’t cover opposing tight ends, as they have allowed 14.47 FD points per game to them on the season. Coming off of a bye week, the Patriots will be prepared to take advantage of that huge edge making Gronk worth the premium.

 

FanDuel Defense - Week 10 DFS Pick

Chicago Bears (vs. CIN, $4,300)

The Bears have been a respectable defense all season, especially at home, and the Packers offense has been non-existent since the loss of Aaron Rodgers. It comes as little surprise that they have an implied total of just 16.25 The Bears will be the chalk defense of the week, but at this price point there is good reason why.

 

More Week 10 DFS Analysis

 

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REAL-TIME FANTASY NEWS

Rhamondre Stevenson

Questionable to Return on Sunday With Eye Injury
Woody Marks

Returns Following Brief Exit on Sunday
Dalton Schultz

Won't Return in Sunday's AFC Divisional Round Game
Aaron Rodgers

Steelers Open to Aaron Rodgers Returning in 2026?
Kawhi Leonard

to Miss Final Two Games of Road Trip
Jarrett Stidham

to Start AFC Championship Game
Zach Charbonnet

Questionable to Return Against 49ers
Atlanta Falcons

Falcons Hiring Kevin Stefanski as Head Coach
Jalen Williams

Ruled Out for Remainder of Meeting with Miami
Naz Reid

Won't Return on Saturday Night
Bo Nix

Suffers Broken Bone in Ankle, Done for Playoffs
Jalen Suggs

Out on Sunday Against Grizzlies
Santi Aldama

Questionable for Sunday's Matchup
Ja Morant

Listed as Probable for Sunday
Tari Eason

Listed as Questionable for Sunday
Herbert Jones

Ruled Out for Sunday
Rudy Gobert

Won't Play Saturday
Paul Reed

Available Saturday
Stephon Castle

is Available on Saturday
Ausar Thompson

Good to Go Against Pacers
Cade Cunningham

Cleared for Saturday's Action
Ziaire Williams

Still Out Sunday
Drake Powell

Won't Play Against Bulls
Green Bay Packers

Packers Sign Head Coach Matt LaFleur to Multi-Year Extension
Josh Giddey

Holds Doubtful Tag for Sunday's Game
Michael Porter Jr.

to Be Rested Sunday
Patrick Williams

Tagged as Questionable for Sunday
Ricky Pearsall

Active for Divisional Round
Sam Darnold

Officially Active for Saturday's Divisional Round Game vs. 49ers
Nikola Jović

Nikola Jovic Active Saturday
Isaiah Jackson

Will Play on Saturday
Tyler Herro

Out Saturday Night
William Carrier

Misses Fourth Consecutive Game
Shayne Gostisbehere

Remains Out Saturday
Jake Evans

Available Saturday
Teuvo Teravainen

Misses Second Straight Game
William Nylander

Out Against Jets
Pat Bryant

Won't Return on Saturday, Ruled Out with a Concussion
Tom Wilson

Could Be an Option Saturday
Leo Carlsson

Out for 3-5 Weeks After Thigh Procedure
Leon Draisaitl

Takes Leave of Absence
New York Giants

John Harbaugh, Giants Finalize Five-Year Deal
Aaron Rodgers

Not Expected to Return to Steelers in 2026
Atlanta Falcons

Kevin Stefanski the Favorite for Falcons Head-Coaching Job
Matt Boldy

Placed on Injured Reserve
Ross Colton

Good to Go Friday
Will Smith

Returns Against Red Wings
Shayne Gostisbehere

Out Friday
Brad Marchand

Remains Out Friday
Joel Armia

Returns From Five-Game Absence
Chris Kreider

a Game-Time Call Friday
Troy Terry

Cutter Gauthier Available Friday
Leo Carlsson

Sits Out Second Consecutive Game
CFB

Darian Mensah Entering Transfer Portal
Sam Darnold

Seahawks "Optimistic" That Sam Darnold Will Play on Saturday
Nico Collins

Officially Ruled Out for Divisional Round
Rome Odunze

Questionable for Divisional Round
J.T. Realmuto

Signs Three-Year Deal to Return to Phillies
Bo Bichette

Agrees to Three-Year Contract With Mets
CFB

Weber State Signs former Ohio State, Cal Quarterback Devin Brown
Bo Bichette

Phillies the "Overwhelming" Favorite to Sign Bo Bichette
Mark Scheifele

Leads Jets to Victory Thursday
Tage Thompson

Records Season-High Five Points Thursday
Jack Eichel

Notches Four Points Thursday
Ilya Sorokin

Shuts Out Oilers With 35 Saves
Josh Lowe

Angels Acquire Josh Lowe in Three-Team Trade
Kyle Tucker

Signs Four-Year Contract With Dodgers
Ricky Pearsall

Questionable to Play on Saturday Night
Sam Darnold

Questionable With Oblique Injury, Expected to Play
Clayton Kershaw

to Pitch for Team USA in World Baseball Classic
Patrick Mahomes

Says Rehab Going "Great," Goal is 2026 Week 1 Return
CFB

Auburn, Ohio State the Lead Suitors for Kyle Parker
CFB

Oregon QB Transfer Bryson Beaver Linked to Georgia, Kentucky
CFB

Jake Merklinger Commits to UConn
Ben Griffin

Looks To Stay Hot In 2026
Ranger Suárez

Ranger Suarez Agrees to Five-Year Deal With Red Sox
CFB

Dante Moore Not Entering 2026 NFL Draft, Will Return to Oregon
CFB

FBS Coaches Unanimously Vote to Expand Redshirt Eligibility to Nine Games
CFB

Ohio State Transfer Mylan Graham Signs with Notre Dame
CFB

Caden Durham Withdraws from Transfer Portal, Will Stay at LSU
Jordan Spieth

Perhaps the Most Intriguing Player at Sony Open
Aaron Rai

Looking For Putting Confidence at Waialae Country Club
Collin Morikawa

Isn't The Safe Play He Used to Be Ahead of Sony Open
Kurt Kitayama

Needs His Putting to Turn Around For Success at Year's First Event
Ryan Weathers

Yankees Add Rotation Depth, Acquire Ryan Weathers in Four-Player Deal
CFB

Georgia Tech the Favorite to Land Justice Haynes?
Nolan Arenado

Cardinals Trade Nolan Arenado to Diamondbacks
Tom Kim

Desperately Needs a Solid Week at Sony Open
Billy Horschel

Hoping For a Fast Start to New Season at Sony Open
Corey Conners

Looks to Have a Return to Form in 2026
PGA

Chris Gotterup a Decent Play at Sony Open
Gary Woodland

Could Prosper at the Sony Open
Keith Mitchell

Unlikely to Contend at Sony Open
Robert MacIntyre

Looking for a Good Performance at the Sony Open
Michael Kim

Hopes to Start Sony Open Better This Week
Tom Hoge

Tries to Erase Poor 2025 Second Half in Hawaii
Brian Harman

Seeks Fresh Start in Hawaii
Eric Cole

Looks to Last Year for Success at Sony Open
Daniel Berger

Starts Off 2026 at Sony Open
Kyle Tucker

Mets Meet With Kyle Tucker

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