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FanDuel Lineup Picks (Week 10) - NFL DFS Advice

FanDuel NFL DFS lineup picks and start 'em, sit' em for Week 10. Daily fantasy football sleepers and lineups cheat sheet for FanDuel DFS GPPs and tournaments.

Welcome to RotoBaller's daily fantasy football FanDuel lineup picks for Week 10 of the NFL season. In this article I will be taking you through the best FanDuel DFS plays of the week for this upcoming Sunday.

These FanDuel lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more.

Good luck with your FanDuel DFS lineups!

 

FanDuel Quarterbacks - Week 10 DFS Picks

Ryan Fitzpatrick (vs. NYJ, $6,100)

Ryan Fitzpatrick will be behind center for the Buccaneers this week and for the foreseeable future. The combination of price and matchup (plus a little narrative) make it difficult to pass in this spot despite the fact that Mike Evans won’t be on the field this week. The Jets are ranked 21st in pass DVOA and the price will allow spending up at other spots on the slate.

Matthew Stafford (vs. CLE, $8,200)

If you’re feeling a safer option than Fitzpatrick this week, Stafford is the quarterback to turn to. Stafford has been good lately, passing for multiple touchdowns in two of his past three games and over 300 yards in all three. He should be able to do each of those things against a hapless Browns pass defense that ranks 28th in pass DVOA for the season. The only risk for Stafford is that the Lions pull ahead quickly without those scores coming through the air, but with the ineptitude of their ground game that seems unlikely.

 

FanDuel Running Backs - Week 10 DFS Picks

Carlos Hyde (vs. NYG, $6,700)

Carlos Hyde hasn’t been anything special on the ground this season which is obviously not a great statement in reference to a running back. On the other hand, he has been very involved in the pass game which has kept his floor at a safe level. When the 49ers have lost by 10 points or less this season, Hyde has seen an average of 23 touches per game. The Giants are just as inept as the 49ers, if not more, so this should be a close game between two bad teams and allow Hyde to see a healthy dose of touches.

Bilal Powell (@TB, $6,000)

With Matt Forte officially out this week, we can look to Powell as a bargain running back that paves the way to Antonio Brown, LeVeon Bell, or Gronk. While the narrative has been that the Jets rushing attack has been an unreliable mess in terms of workload, the absence of Forte should open sufficient volume for Powell to take advantage of. The Bucs are far from tough on opposing running backs, allowing big games to Adrian Peterson, LeSean McCoy, and the Saints running back committee of late, opening up some more nice value at the running back position.

 

FanDuel Wide Receivers - Week 10 DFS Picks

A.J. Green (@TEN, $7,900) 

A.J. Green has been a story this week, but not because of his play. He should be motivated to perform as a result and he’s in a decent spot to do so. Though Tennessee has shown improvement on defense, most of that improvement has come against opposing rushing attacks. If the Bengals are smart, that’s a big if, they will pepper A.J. Green with targets as has a six-inch height advantage over otherwise impressive rookie Adoree’ Jackson.

Marvin Jones (vs. CLE, $6,400)

Golden Tate has been a reliable option this season, but the price disparity between he and Marvin Jones on FanDuel doesn’t make much sense. Over the past three games, in which Matt Stafford has gotten on track, Jones has put up 18.6, 15.8, and 26.2 FD points respectively. In an A+ matchup there’s no reason to go away from Jones.

 

FanDuel Tight End - Week 10 DFS Pick

Rob Gronkowski (@DEN, $8,100) 

Gronk is a relatively easy choice this week, assuming the ability or desire to pay up at the position. The Broncos still can’t cover opposing tight ends, as they have allowed 14.47 FD points per game to them on the season. Coming off of a bye week, the Patriots will be prepared to take advantage of that huge edge making Gronk worth the premium.

 

FanDuel Defense - Week 10 DFS Pick

Chicago Bears (vs. CIN, $4,300)

The Bears have been a respectable defense all season, especially at home, and the Packers offense has been non-existent since the loss of Aaron Rodgers. It comes as little surprise that they have an implied total of just 16.25 The Bears will be the chalk defense of the week, but at this price point there is good reason why.

 

More Week 10 DFS Analysis

 

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REAL-TIME FANTASY NEWS

Luke Kennard

Out On Saturday Night Against Lakers, Will Miss Second Straight Game
Maxi Kleber

Will Make Season Debut Saturday Night Against Hawks
Dean Wade

Questionable For Saturday Night Against Bulls
Larry Nance Jr.

Listed As Questionable For Saturday Night Against Bulls
Jared McCain

Available For Saturday Night Against Raptors
Ryker Evans

Comes Off Injured Reserve
Bilal Coulibaly

Officially Out For Saturday Night Against Mavericks
Joey Daccord

Kraken Place Joey Daccord on Injured Reserve
Jordan Kyrou

Rejoins Blues Lineup Saturday
Anthony Cirelli

Won't Play on Saturday
Casey Mittelstadt

Misses Meeting With Maple Leafs
Charlie McAvoy

Sits Out Saturday's Game
Sean Monahan

a Game-Time Decision Saturday
Tetairoa McMillan

Trending Towards Playing in Week 10
Jamal Murray

Listed As Questionable For Saturday Night Against Pacers
Aaron Gordon

Questionable For Saturday Night Against Pacers
Norman Powell

Listed As Probable For Saturday Night Against Blazers
Jaime Jaquez Jr.

Listed Questionable For Saturday Night Against Blazers
Bam Adebayo

Ruled Out For Second Straight Game
A.J. Brown

Off Final Injury Report, Set To Play Monday Versus Packers
Jalen Johnson

Questionable For Saturday Night Against Lakers
Saquon Barkley

Cleared From Final Injury Report, Good To Go For Monday
Nickeil Alexander-Walker

Listed As Questionable For Saturday Against Lakers
Ayo Dosunmu

Listed As Probable For Saturday Night Against Cleveland
Jakob Poeltl

Ruled Out For Saturday's Matchup Against Sixers
Justin Fields

Set to Start in Week 10 Against Browns
Aaron Jones Sr.

Expected to Play Sunday Against Ravens
Kristaps Porzingis

Ruled Out Versus the Lakers
Darius Garland

Resting on Saturday Night
Kyshawn George

in Danger of Missing Another Game on Saturday
Dereck Lively II

Not Expected to Face the Wizards
Daniel Gafford

on the Injury Report for Saturday Night
Anthony Davis

Questionable to Play Versus the Wizards
Brock Purdy

Could Return in Week 11
Jayden Daniels

Could Return After Three Weeks
Kyler Murray

Future with Cardinals in Limbo
Tyrone Tracy Jr.

Will Remain the Giants' Starting Running Back
Artemi Panarin

Ends Dry Spell With Three-Point Outing
Marcus Johansson

Extends Point Streak to Eight Games
Spencer Knight

Posts First Shutout of the Season
Matt Duchene

to Remain Out Saturday
Zayne Parekh

Expected to "Miss a Little Bit of Time"
Frank Nazar

Day-to-Day Following Friday's Early Exit
Rashid Shaheed

Could Play Extensively in Seahawks Debut
Aaron Judge

Headlines AL Silver Slugger Award Winners
Terry McLaurin

Officially Ruled Out for Week 10
Puka Nacua

Will Play in Week 10
William Eklund

Moved to Injured Reserve
Gustav Nyquist

Expected to Remain Out Friday
Thatcher Demko

Questionable to Play This Weekend
Brock Purdy

Questionable Again, Won't Start in Week 10
Rasmus Dahlin

Takes Leave of Absence
Filip Hallander

to Miss at Least Three Months With Blood Clot
Kevin Bahl

a Game-Time Call Friday
Patrick Kane

Returns to Action Friday
Garrett Wilson

Listed as Questionable for Week 10, Expected to Play
Shohei Ohtani

Headlines List of NL Silver Slugger Winners
MLB

Munetaka Murakami Officially Being Posted on Friday
Alvin Kamara

Listed as Questionable for Week 10
Aaron Jones Sr.

Questionable for Week 10
Brian Thomas Jr.

Ruled Out For Week 10
D'Andre Swift

Listed as Questionable for Week 10
J.K. Dobbins

Getting Second Opinion on Foot Injury
Kyler Murray

Expected to Return This Season
Harold Fannin Jr.

Questionable for Sunday
Randy Brown

Set For UFC Vegas 111 Main Event
Gabriel Bonfim

Looks To Extend His Win Streak
Joseph Morales

A Favorite At UFC Vegas 111
Matt Schnell

Set For UFC Vegas 111 Co-Main Event
Uros Medic

Aims To Win Back-To-Back Fights
Muslim Salikhov

Looks For His Fourth Consecutive Win
Chris Padilla

Looks To Remain Unbeaten In The UFC
Chris Kreider

Extends Goal Streak to Four Games
Ismael Bonfim

Looks To Get Back In The Win Column
Marco Tulio

Looks To Remain Undefeated In The UFC
Christian Leroy Duncan

Set To Open Up UFC Vegas 111 Main Card
Kyle Tucker

Headlines List of 13 Players to Receive Qualifying Offers
Pete Fairbanks

Becomes a Free Agent
CFB

Luke Fickell Will Return as Wisconsin's Head Coach in 2026
Bo Bichette

Blue Jays Extend Qualifying Offer to Bo Bichette
Craig Stammen

Named Padres New Manager
Jorge Polanco

Declines his 2026 Option to Become a Free Agent
Chris Sale

Braves Picking Up Chris Sale's 2026 Option
Michael Thorbjornsen

Poised to Continue Hot Play in Mexico
Davis Riley

Struggling to Find Form Ahead of World Wide Technology Championship
Taylor Montgomery

Leaning on Putter at World Wide Technology Championship
Stephan Jaeger

Offers Strong Value at World Wide Technology Championship
Ben Griffin

Looks to Stay Hot at El Cardonal
Nick Dunlap

Looking to Find His Game at El Cardonal
Wyndham Clark

Searching for Consistency at El Cardonal
Michael Brennan

Aims to Extend Fairytale Start at El Cardonal
Shane Bieber

Staying in Toronto for 2026
Salvador Perez

Agrees to Two-Year Extension With Royals
Trevor Story

Opts in for Remaining Two Years on his Contract
Yu Darvish

to Miss All of 2026 Following Flexor-Tendon Surgery
Shota Imanaga

Becomes a Free Agent
Luis Robert Jr.

White Sox Pick Up 2026 Option on Luis Robert Jr.
CFB

LJ Martin Expected to Play in Top-10 Matchup Against Texas Tech
PGA

LIV Golf Expanding To 72-Hole Format In 2026
Atlanta Braves

Braves Hire Walt Weiss as Their Next Manager
Kris Bubic

Cleared to Begin a Throwing Program
Brandon Woodruff

Declines Mutual Option for 2026
Freddy Peralta

Brewers Exercise 2026 Option on Freddy Peralta
Lucas Giolito

Declines his 2026 Player Option
J.J. Spaun

Finishes Sixth at Procore Championship
PGA

Matti Schmid Finishes Tied for 46th at Baycurrent Classic
Keith Mitchell

Finishes Tied for 10th at Baycurrent Classic
Si Woo Kim

Finishes Tied for 21st at Genesis Championship
Mackenzie Hughes

Misses The Cut at Sanderson Farms Championship
Max Greyserman

Finishes Second at Baycurrent Classic
Austin Eckroat

Finishes Tied for 56th at Baycurrent Classic
Luke Clanton

Finishes Tied for 56th at Bank of Utah Championship
Pete Alonso

Officially Opts Out of his Contract With Mets
Kyle Larson

Wins His Second NASCAR Cup Series Championship at Phoenix
Ryan Blaney

Concludes the 2025 Season with A Win at Phoenix
William Byron

Strong Championship Effort Ends With Late-Race Flat-Tire Crash
Denny Hamlin

Overtime Four-Tire Call Costs Denny Hamlin the Championship
Chase Briscoe

Championship Bid Never Really Started After Two Tire Failures
Brad Keselowski

Nearly Steals Phoenix Race
David Onama

Suffers First-Round TKO Loss
Steve Garcia

Scores First-Round TKO Win
Ante Delija

Suffers His First UFC Loss
CFB

Dylan Raiola Suffers Season-Ending Injury
Waldo Cortes-Acosta

Gets Knockout Win
Themba Gorimbo

Drops Decision At UFC Vegas 110
Jeremiah Wells

Gets Back In The Win Column
Yadier del Valle

Remains Undefeated
Isaac Dulgarian

Cut By UFC Following Submission Loss
Daniel Frunza

Still Winless In The UFC
Charles Radtke

Dominates Daniel Frunza
Allan Nascimento

Gets Submission Win

RANKINGS

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K
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