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FanDuel Lineup Picks (Week 1) - NFL DFS Advice

Tom Vecchio's FanDuel NFL DFS lineup picks and start 'em, sit' em for Week 1. Daily fantasy football sleepers and lineups cheat sheet for FanDuel DFS GPPs and tournaments.

RotoBallers, welcome to Week 1 of the daily fantasy football season. In this column, you will find my recommended FanDuel DFS Lineup Picks to target for Week 1 of the NFL season.

The goal is to identify players to start on FanDuel this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the FanDuel price.

Let's find some DFS lineup sleepers, and win on FanDuel. Good luck in Week 1! Find me @DFS_Tom if you have any questions.

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FanDuel Quarterbacks - Week 1 DFS Picks

Kirk Cousins - QB, MIN vs SF (FD - $7,600)

Cousins is making his debut for the Vikings this week and he has a great matchup to make a lasting first impression. He is facing off against the 49ers, who finished last season with the 28th DVOA against the pass and were a team you could attack on a weekly basis. Cousins has a significant upgrade in terms of the offensive weapons surrounding him, namely Stefon Diggs and Adam Thielen. There hasn't been much chatter about Cousins this week and if he were to air the ball out a bit more this week in his debut, it wouldn't be too much of a shock. The Vikings come in with an implied team total sitting at 26.3, which is third highest on the slate, so we are looking at nearly four touchdowns from them. Two passing touchdowns is firmly in play in play for him, along with 300-yard ceiling is certainly in play for him this week.

Drew Brees - QB, NO vs TB (FD - $8,400)

Everyone around the industry is talking about how good of a play Alvin Kamara is this week since the Saints are at home and come in with an implied team total of 29.5, which is highest on the slate. Well, if you are looking for some leverage in tournaments to get away from the ownership on Kamara, then Brees is the call. You should be looking to stack him with Michael Thomas, to really have some nice tournament upside, as they have a high correlation in terms of offensive production.

 

FanDuel Running Backs - Week 1 DFS Picks

Joe Mixon - RB, CIN @ IND (FD - $6,900)

Mixon and the Bengals are one of my favorite stacks for this week and we could be in for a bit of a shootout vs Indianapolis. Last season, the Colts finished with the 31st DVOA against running backs in the passing game, along with being 32nd DVOA overall vs the pass. Mixon saw an average of 12 rushing attempts per game, along with two targets per game last season. He was a bit inconsistent at times last year, but the news coming out of preseason puts him in a positive light and should see an increased role in the offense.

David Johnson - RB, ARI vs WAS (FD - $8,600)

Johnson is back this season after missing nearly all of last year due to a wrist injury. He is fully healthy this year and hopefully returns to his 20+ carries per game, making him a fantastic cash game option this and nearly every week. The Cardinals are at home and only a -1 favorite in a game which has a low over-under only sitting at 44. Love the price on him this week and the matchup, since he is up against this Redskins team, who had the 29th DVOA vs the run last season.

 

FanDuel Wide Receivers - Week 1 DFS Picks

Taywan Taylor - WR, TEN @ MIA (FD - $4,500)

If you are looking for a cheap tournament option, Taylor is your guy this week. He is minimum salary on FanDuel this week and is facing off against a Dolphins team, who were 29th DVOA vs the pass last year. Taylor put up very impressive numbers in the preseason and when he plays out of the slot, they are drawing up plays for him on screens. He has big-play upside and hopefully comes in at lower ownership.

Chris Hogan - WR, NE vs HOU (FD - $6,700)

The Patriots came out of camp with only three wide receivers on their roster, so we should see a condensed target share in the passing game, where Hogan should be one of the top options. Hogan had over six targets per game last season and is the most reliable receiver for Tom Brady. He is a cash game option this week and we should only see his price increase until Edelman returns from his suspension, so buy in before his price jumps up.

 

FanDuel Tight End - Week 1 DFS Pick

Jack Doyle - TE, IND vs CIN (FD - $5,600)

Doyle finished last season with the second most receptions among tight ends but dealt with some terrible play from his quarterbacks. This year, hopefully, things will be different now that Andrew Luck is back behind center. The Bengals have been a flowchart team in terms of rostering tight ends against them, as they had the 30th DVOA against TE. Doyle isn't too expensive and offers a nice floor of points with his receptions, in what should be a high scoring game.

Kyle Rudolph - TE, MIN vs SF (FD - $5,900)

Rudolph can always be a bit of risky play since he is generally touchdown dependant in order to reach value. He averaged only five targets and three receptions per game, which certainly isn't explosive, but makes a nice stacking option for tournaments with Cousins.

 

FanDuel Defense - Week 1 DFS Pick

Arizona Cardinals - DEF vs Washington Redskins (FD - $4,100)

The Cardinals are at home in a lower scoring game, so this could be the time to roster their defense, against what should be a relatively non-threatening offense. I've always been a fan of spending down a bit a defense and with the Cardinals averaging about two sacks per game last season, with allowing about 20 points per game. The Redskins have an implied team total of 21.5, which is in the lower third of teams this week.

 

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REAL-TIME FANTASY NEWS

Devon Toews

to Miss at Least Two Weeks
Gabriel Landeskog

Out for Several Weeks
Jamie Drysdale

Makes Early Exit Tuesday
Bobby Brink

Injured in Tuesday's Win
Adam Henrique

Expected to Miss Time
Brad Marchand

Dealing With Lingering Health Issue
Haydn Fleury

Hospitalized Tuesday
Moussa Diabaté

Ryan Kalkbrenner Out, Moussa Diabate Probable Wednesday
Brandon Miller

Listed as Probable Wednesday
Alex Caruso

Absent for Second Consecutive Game
Nicolas Claxton

Available Wednesday
Moritz Wagner

Still Out Wednesday
Franz Wagner

Not Ready to Return Wednesday
Jalen Suggs

Remains Out Wednesday
Draymond Green

Questionable to Suit Up Wednesday
Jalen Smith

Ruled Out for Second Straight Game
Matas Buzelis

Could Miss First Game of the Season Wednesday
Coby White

May Skip Wednesday's Game
Cade Cunningham

Probable for Wednesday
Isaiah Hartenstein

to Remain Out Wednesday
Kelly Oubre Jr.

Could Return to Action Wednesday
Tim Hardaway Jr.

May Remain Out Wednesday
Christian Braun

Listed as Questionable for Wednesday
Aaron Gordon

Iffy for Wednesday
Jamal Murray

Considered Questionable for Wednesday Night
Max Strus

to Miss Another Month
Vince Williams Jr.

Making Return Tuesday Against Spurs
Trae Young

Listed as Questionable for Wednesday
New York Giants

John Harbaugh Expected to be Favorite to Become New Giants Head Coach
Mason Marchment

Out Tuesday
Sean Monahan

Available Tuesday
Jason Zucker

Set to Return From 11-Game Absence
Matvei Michkov

a Game-Time Call Tuesday
Matthew Schaefer

Cleared for Action Tuesday
Baltimore Ravens

John Harbaugh Won't Return as Ravens Head Coach
Adam Fox

Landing Back on Long-Term Injured Reserve
Seth Jarvis

Back for Hurricanes Tuesday
Bo Bichette

Unlikely to Return to Toronto?
Jordan Love

Ready to Start in Wild-Card Game Against Bears
CFB

Jadan Baugh Staying with Florida for Junior Season
Washington Commanders

Commanders "Mutually" Parting Ways With OC Kliff Kingsbury
CFB

Byrum Brown Officially Commits to Auburn
CFB

Austin Simmons Signing with Missouri
Jake McCabe

to Sit Out One Week
Hampus Lindholm

to Miss Time
Christian Dvorak

Flyers Sign Christian Dvorak to Five-Year Extension
Igor Shesterkin

Exits With Lower-Body Injury Monday
Joel Armia

Hurt in Monday's Win
Anze Kopitar

Sustains Lower-Body Injury Monday
Matthew Schaefer

a Game-Time Call Tuesday
CFB

Ty Simpson Undecided on 2026 Plans
CFB

Quarterback AJ Hill Following Ryan Silverfield to Arkansas
Atlanta Falcons

Falcons Have Requested an Interview With Klint Kubiak
Deshaun Watson

Browns Expect Deshaun Watson to be on the Team Next Year
Wan'Dale Robinson

Dealing With Fractured Ribs
Cam Skattebo

Hopes to be Back by Training Camp
Cameron Ward

Won't Need Surgery on his Shoulder
Davante Adams

Rams Expect Davante Adams to Return in Wild-Card Round
Arizona Cardinals

Cardinals Fire Head Coach Jonathan Gannon
Las Vegas Raiders

Raiders Fire Head Coach Pete Carroll
Malik Nabers

Unsure if He Will Be Ready for Week 1 of 2026 Season
CFB

Trinidad Chambliss Will Return to Ole Miss If Granted Sixth Year of Eligibility
Cincinnati Bengals

Zac Taylor Will Return as Bengals Head Coach in 2026
New York Giants

Giants Expected to Show Interest in Former Browns Head Coach Kevin Stefanski
Daniel Jones

Colts, Daniel Jones Appear to Have "Mutual Interest" in a 2026 Reunion
Cleveland Browns

Browns Fire Kevin Stefanski After Another Losing Season
Zay Flowers

Goes Off for 138 Yards, Two Touchdowns in Loss
Bo Bichette

Phillies Have Interest in Bo Bichette
Amon-Ra St. Brown

Dominates in Week 18 Win
Cameron Ward

Believed to Have Grade 3 AC Joint Sprain in Right Shoulder
Colston Loveland

Leads Bears in Targets, Receptions, Receiving Yards in Week 18
Kansas City Royals

Matt Quatraro Signs Three-Year Extension With Royals
CFB

Transfer QB Billy Edwards Commits to North Carolina
CFB

Sam Leavitt Visiting Texas Tech on Saturday
CFB

DJ Lagway Expected To Visit Florida State
Kyle Tucker

Blue Jays "Remain the Favorite" to Sign Kyle Tucker
CFB

Joey Aguilar Undergoes Surgery to Remove Tumor on Friday
CFB

Texas the "Team to Beat" for Transfer Running Back Isaac Brown
CFB

Rocco Becht to Follow Matt Campbell to Penn State?
CFB

Texas Targeting Cam Coleman in Transfer Portal
CFB

Former Texas Running Back CJ Baxter Visiting Kentucky
CFB

Beau Pribula Visiting Virginia Tech, Georgia Tech
Bo Bichette

Yankees Showing Interest in Bo Bichette
Houston Astros

Astros Sign Tatsuya Imai to Three-Year Deal

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