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FanDuel Lineup Picks (Week 1) - NFL DFS Advice

Tom Vecchio's FanDuel NFL DFS lineup picks and start 'em, sit' em for Week 1. Daily fantasy football sleepers and lineups cheat sheet for FanDuel DFS GPPs and tournaments.

RotoBallers, welcome to Week 1 of the daily fantasy football season. In this column, you will find my recommended FanDuel DFS Lineup Picks to target for Week 1 of the NFL season.

The goal is to identify players to start on FanDuel this week based on various factors including the opponent, the player's opportunity, analysis of the game's matchups, and the FanDuel price.

Let's find some DFS lineup sleepers, and win on FanDuel. Good luck in Week 1! Find me @DFS_Tom if you have any questions.

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

FanDuel Quarterbacks - Week 1 DFS Picks

Kirk Cousins - QB, MIN vs SF (FD - $7,600)

Cousins is making his debut for the Vikings this week and he has a great matchup to make a lasting first impression. He is facing off against the 49ers, who finished last season with the 28th DVOA against the pass and were a team you could attack on a weekly basis. Cousins has a significant upgrade in terms of the offensive weapons surrounding him, namely Stefon Diggs and Adam Thielen. There hasn't been much chatter about Cousins this week and if he were to air the ball out a bit more this week in his debut, it wouldn't be too much of a shock. The Vikings come in with an implied team total sitting at 26.3, which is third highest on the slate, so we are looking at nearly four touchdowns from them. Two passing touchdowns is firmly in play in play for him, along with 300-yard ceiling is certainly in play for him this week.

Drew Brees - QB, NO vs TB (FD - $8,400)

Everyone around the industry is talking about how good of a play Alvin Kamara is this week since the Saints are at home and come in with an implied team total of 29.5, which is highest on the slate. Well, if you are looking for some leverage in tournaments to get away from the ownership on Kamara, then Brees is the call. You should be looking to stack him with Michael Thomas, to really have some nice tournament upside, as they have a high correlation in terms of offensive production.

 

FanDuel Running Backs - Week 1 DFS Picks

Joe Mixon - RB, CIN @ IND (FD - $6,900)

Mixon and the Bengals are one of my favorite stacks for this week and we could be in for a bit of a shootout vs Indianapolis. Last season, the Colts finished with the 31st DVOA against running backs in the passing game, along with being 32nd DVOA overall vs the pass. Mixon saw an average of 12 rushing attempts per game, along with two targets per game last season. He was a bit inconsistent at times last year, but the news coming out of preseason puts him in a positive light and should see an increased role in the offense.

David Johnson - RB, ARI vs WAS (FD - $8,600)

Johnson is back this season after missing nearly all of last year due to a wrist injury. He is fully healthy this year and hopefully returns to his 20+ carries per game, making him a fantastic cash game option this and nearly every week. The Cardinals are at home and only a -1 favorite in a game which has a low over-under only sitting at 44. Love the price on him this week and the matchup, since he is up against this Redskins team, who had the 29th DVOA vs the run last season.

 

FanDuel Wide Receivers - Week 1 DFS Picks

Taywan Taylor - WR, TEN @ MIA (FD - $4,500)

If you are looking for a cheap tournament option, Taylor is your guy this week. He is minimum salary on FanDuel this week and is facing off against a Dolphins team, who were 29th DVOA vs the pass last year. Taylor put up very impressive numbers in the preseason and when he plays out of the slot, they are drawing up plays for him on screens. He has big-play upside and hopefully comes in at lower ownership.

Chris Hogan - WR, NE vs HOU (FD - $6,700)

The Patriots came out of camp with only three wide receivers on their roster, so we should see a condensed target share in the passing game, where Hogan should be one of the top options. Hogan had over six targets per game last season and is the most reliable receiver for Tom Brady. He is a cash game option this week and we should only see his price increase until Edelman returns from his suspension, so buy in before his price jumps up.

 

FanDuel Tight End - Week 1 DFS Pick

Jack Doyle - TE, IND vs CIN (FD - $5,600)

Doyle finished last season with the second most receptions among tight ends but dealt with some terrible play from his quarterbacks. This year, hopefully, things will be different now that Andrew Luck is back behind center. The Bengals have been a flowchart team in terms of rostering tight ends against them, as they had the 30th DVOA against TE. Doyle isn't too expensive and offers a nice floor of points with his receptions, in what should be a high scoring game.

Kyle Rudolph - TE, MIN vs SF (FD - $5,900)

Rudolph can always be a bit of risky play since he is generally touchdown dependant in order to reach value. He averaged only five targets and three receptions per game, which certainly isn't explosive, but makes a nice stacking option for tournaments with Cousins.

 

FanDuel Defense - Week 1 DFS Pick

Arizona Cardinals - DEF vs Washington Redskins (FD - $4,100)

The Cardinals are at home in a lower scoring game, so this could be the time to roster their defense, against what should be a relatively non-threatening offense. I've always been a fan of spending down a bit a defense and with the Cardinals averaging about two sacks per game last season, with allowing about 20 points per game. The Redskins have an implied team total of 21.5, which is in the lower third of teams this week.

 

More Weekly DFS Analysis




REAL-TIME FANTASY NEWS

Patrick Mahomes

Takes Part in First OTA Practice on Tuesday
Los Angeles Chargers

Derwin James Jr. Becomes Highest-Paid Safety for the Second Time in his Career
Chris Brooks

Emerging as Top Handcuff to Stash?
MarShawn Lloyd

Sees Short-Term Value Soar
Jared McCain

Moves into Starting Five
Boston Celtics

Joe Mazzulla Wins Coach of the Year
Jalen Williams

is Ruled Out for Game 5 on Tuesday
Bucky Irving

is Expected to be Ready for Training Camp
Zion Williamson

to See More Versatile Role
Parker Washington

Jaguars Think Parker Washington Can Replicate Second-Half Production
Cleveland Cavaliers

Kenny Atkinson to Remain Cavaliers Head Coach Next Season
Josh Jacobs

Arrested on Five Charges, Booked Into Jail
Claude Giroux

Planning to Return for 20th NHL Campaign
Josh Sweat

Cardinals Receiving Trade Calls on Josh Sweat
Carter Hart

Aiming for Sixth Consecutive Win Tuesday
Tetairoa McMillan

Working With the Training Staff on Tuesday
Evgeni Malkin

Inks New One-Year Deal With Penguins
Mackenzie Blackwood

in Net for Game 4 Against Golden Knights
Valeri Nichushkin

a Game-Time Call Tuesday
Nathan MacKinnon

Will Suit Up Tuesday
Jerome Ford

Is it Time for Dynasty Managers to Drop Jerome Ford?
John Metchie III

Poised for Breakout Season with New Team in 2026?
Jalen Milroe

Is Jalen Milroe Still Worth Stashing in Dynasty Formats Entering 2026?
Kyle Pitts Sr.

Is Kyle Pitts Sr. a Dynasty Sell-High Candidate Coming Off Breakout Season?
Nico Collins

Agrees to Contract Adjustment with Texans
Chris Brooks

Carries Buy-Low Dynasty Appeal into 2026
Ben Griffin

Looking to Repeat This Week at Colonial
Rasmus Hojgaard

a Player to Avoid at Charles Schwab Challenge
Hideki Matsuyama

Needs Solid Driving Week at Charles Schwab Challenge
Justin Thomas

Trending Well Ahead of Charles Schwab Challenge
Akshay Bhatia

Lacking Driving Prowess Needed at Colonial Country Club
NFL

NFL Unlikely to Expand to 18 Regular-Season Games by 2027
Sahith Theegala

Searching For Swing at Charles Schwab Challenge
Lamar Jackson

in Attendance at OTAs This Week
Bucky Irving

Expected Back in the Summer or Fall
CFB

DJ Lagway Looking to Rebound at Baylor
CFB

Josh Hoover Tasked With Leading Indiana Back to the Playoffs
CFB

Braylon Staley the Next 1,000-Yard Tennessee Receiver?
Jalen Tolbert

Does Jalen Tolbert Have Short-Term Dynasty Appeal?
CFB

Ahmad Hardy's Return Timeline Remains Unclear
Travis Etienne Jr.

Is Travis Etienne Jr. Still a Dynasty RB1 Following Change of Scenery?
Breece Hall

Extension Solidifies His Dynasty Outlook
Evan Mobley

Finishes Season-Ending Loss With 15 Points
James Harden

Wants to Stay in Cleveland
Donovan Mitchell

Remains Committed to Cavaliers
Mikal Bridges

Cools Off in Game 4 Against Cavaliers
OG Anunoby

Active on Both Ends in Blowout Win
Karl-Anthony Towns

Leads Knicks in Scoring During Series-Clincher
Jalen Brunson

Named Eastern Conference Finals MVP
Ivan Demidov

Contributes an Assist in Losing Effort
Lane Hutson

Records Power-Play Goal in Game 3 Loss
Frederik Andersen

Enjoys Another Easy Night at the Office in Game 3
Shayne Gostisbehere

Scores First Postseason Goal
Taylor Hall

Ends Four-Game Goal Drought
Andrei Svechnikov

Scores Game 3 Winner in Overtime
Gage Jump

Athletics to Promote Top Pitching Prospect Gage Jump to Major Leagues
Tatsuya Imai

Two Relievers Combine to No-Hit the Rangers on Monday
Dennis Schröder

Dennis Schroder is Ruled Out for Game 4 on Monday
Michael Porter Jr.

Nets Could Trade Michael Porter Jr.
Ajay Mitchell

is Ruled Out for Game 5
Jalen Williams

is Tagged as Questionable for Game 5
Valeri Nichushkin

Nathan MacKinnon, Valeri Nichushkin Uncertain for Game 4
Oliver Kapanen

Sitting as Healthy Scratch Monday
Max Domi

Out Indefinitely Due to Offseason Surgery Complications
Dylan Cease

Heading to Injured List With Hamstring Injury
Daniel Suarez

Wins at Charlotte in Rain-Shortened Coca-Cola 600
Christopher Bell

Finishes as the Runner-Up in the Coca-Cola 600 at Charlotte
Denny Hamlin

Falls Short of Winning and Places Third at Charlotte
Tyler Reddick

Places Fourth After Leading Laps at Charlotte
Kyle Larson

Strong and Consistent Day Ends in Fifth at Charlotte
Devon Toews

Logs Two Assists In Game 3 Defeat
Brett Howden

Nets 10th Postseason Goal
Mitchell Marner

Delivers Two Assists in Comeback Victory
Mark Stone

Returns With Multi-Point Effort
Valeri Nichushkin

Exits Early Sunday
Nathan MacKinnon

Hurt in Game 3 Loss
Isaiah Hartenstein

Provides Steady Production in Defeat
Chet Holmgren

Has a Quiet Offensive Night on Sunday
Shai Gilgeous-Alexander

Held Under 20 Points in Game 4
Stephon Castle

Hands Out Six Assists in Game 4 Win
Devin Vassell

Tallies 13 Points in Game 4 Win
Dylan Cease

Removed From Sunday's Start With Hamstring Discomfort
Vladimir Guerrero Jr.

Exits Sunday's Game Early with Elbow Contusion
MLB

Reds-Cardinals Game Postponed on Sunday
Edward Cabrera

Cubs Place Edward Cabrera on the 15-Day Injured List
Denny Hamlin

the Favorite to Win at Charlotte
Tyler Reddick

on Pole for Coca-Cola 600
Christopher Bell

Could Break Out of Slump
Kyle Larson

May have A Solid Day at Charlotte
Ryan Blaney

Is A DFS Risk for Charlotte Lineups
William Byron

Could have A Great DFS Performance at Charlotte
Chase Briscoe

Is A Solid Tournament Option for Charlotte DFS Lineups
Ty Gibbs

May not be Worth his Salary for Charlotte DFS Lineups
Chris Buescher

May be a Sneaky Tournament Option for Charlotte Lineups
NASCAR

Bubba Wallace Has Favorable Upside for Charlotte DFS Lineups
Ross Chastain

Is A Strong Addition for DFS Lineups at Charlotte
Austin Dillon

Should Fantasy Managers Roster Austin Dillon for Charlotte DFS Lineups?
Chase Elliott

Should Be Strong at Charlotte
Carson Hocevar

Confident for Coca-Cola 600
Corey Heim

a Chalk DFS Pick at Charlotte
Michael McDowell

Is Michael McDowell A Tournament Option for Charlotte Lineups?
MLB

Orioles-Tigers Game Postponed on Saturday
MLB

Rays-Yankees Postponed on Saturday
Mickey Moniak

Heads to Injured List With Ankle Sprain
Jackson Merrill

has Sore Ribs, Expected to Avoid Injured List
CFB

Jaron-Keawe Sagapolutele Looking to Take Sophomore Leap
CFB

Jadan Baugh Primed to Lead Florida Offense in 2026
CFB

LSU Hires Ed Orgeron As Special Assistant
CFB

North Carolina and South Carolina Cancel Home-And-Home Series
CFB

Confidence High in Mississippi State's Kamario Taylor
MLB

Reds-Cardinals Game Postponed on Friday
Trevor Story

has Hernia Surgery, Expected to Miss 6-10 Weeks
Roman Anthony

Dealing With Sprained Ligament in his Finger
Ronald Acuña Jr.

Ronald Acuna Jr. Exits Early, X-Rays Come Back Negative
Robby Snelling

Will Undergo Tommy John Surgery
Jackson Merrill

Tweaks his Back on Wednesday, Pulled Early
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF